The Fe3O4@SiO2 composite nanoparticles were obtained from as-synthesized magnetite (Fe3O4) nanoparticles through the modified St?ber method. Then, the Fe3O4 nanoparticles and Fe3O4@SiO2 composite nanoparticles were ch...The Fe3O4@SiO2 composite nanoparticles were obtained from as-synthesized magnetite (Fe3O4) nanoparticles through the modified St?ber method. Then, the Fe3O4 nanoparticles and Fe3O4@SiO2 composite nanoparticles were characterized by means of X-ray diffraction (XRD), Raman spectra, scanning electron microscope (SEM) and vibrating sample magnetometer (VSM). Recently, the studies focus on how to improve the dispersion of composite particle and achieve good magnetic performance. Hence effects of the volume ratio of tetraethyl orthosilicate (TEOS) and magnetite colloid on the structural, morphological and magnetic properties of the composite nanoparticles were systematically investi-gated. The results revealed that the Fe3O4@SiO2 had better thermal stability and dispersion than the magnetite nanoparticles. Furthermore, the particle size and magnetic property of the Fe3O4@SiO2 composite nanoparticles can be adjusted by changing the volume ratio of TEOS and magnetite colloid.展开更多
Enrichment of trace bioactive constituents and metabolites from complex biological samples is challenging.This study presented a one-pot synthesis of magnetic polydopamine nanoparticles(Fe3O4@-SiO2@PDA NPs)with multip...Enrichment of trace bioactive constituents and metabolites from complex biological samples is challenging.This study presented a one-pot synthesis of magnetic polydopamine nanoparticles(Fe3O4@-SiO2@PDA NPs)with multiple recognition sites for the magnetic dispersive solid-phase extraction(MDSPE)of ginsenosides from rat plasma treated with white ginseng.The extracted ginsenosides were characterized by combining an ultra-high-performance liquid chromatography coupled to a highresolution mass spectrometry with supplemental UNIFI libraries.Response surface methodology was statistically used to optimize the extraction procedure of the ginsenosides.The reusability of Fe3O4@-SiO2@PDA NPs was also examined and the results showed that the recovery rate exceeded 80%after recycling 6 times.Furthermore,the proposed method showed greater enrichment efficiency and could rapidly determine and characterize 23 ginsenoside prototypes and metabolites from plasma.In comparison,conventional methanol method can only detect 8 ginsenosides from the same plasma samples.The proposed approach can provide methodological reference for the trace determination and characterization of different bioactive ingredients and metabolites of traditional Chinese medicines and food.展开更多
Novel magnetic core/shell bimetallic Au/Cu nanoparticles(Fe_3O_4@SiO_2-Au/Cu NPs) were prepared using SiO_2-coated iron oxide(Fe_3O_4@SiO_2) as a supported material. The magnetic Fe_3O_4 colloidal nanocrystal clus...Novel magnetic core/shell bimetallic Au/Cu nanoparticles(Fe_3O_4@SiO_2-Au/Cu NPs) were prepared using SiO_2-coated iron oxide(Fe_3O_4@SiO_2) as a supported material. The magnetic Fe_3O_4 colloidal nanocrystal clusters(CNCs) as nano-core were modified with a silica coating for improvement stability and superficial area of the Au-Cu particles. The morphological structure and chemical composition of the Fe_3O_4@SiO_2-Au/Cu NPs were characterized with high-resolution transmission electron microscopy(HRTEM), energy-dispersive X-ray(EDX) and X-ray photoelectron spectroscopy(XPS) analyses. The Au and Cu NPs were deposited on the SiO_2 surface in a highly dense and well dispersed manner with an average size of approximately 5 nm. The Fe_3O_4@SiO_2-Au/Cu NPs as magnetic nano-catalysts were applied to the Ullmann coupling reaction of bromamine acid to synthesize 4,40-diamino-1,10-dianthraquinonyl-3,30-disulfonic acid(DAS). The prepared Fe_3O_4@SiO_2-Au/Cu NPs exhibited efficient catalytic activity with higher conversion and selectivity. A bromamine acid conversion of 97.35% and selectivity for DAS of 88.67% were obtained in aqueous medium. The magnetic nano-catalysts can be readily separated from the reaction system and reused. This new nano-catalytic reaction represents a useful and attractive cleaner production system. The new catalyst system has important and potential applications in dye and pigment industry.展开更多
Novel multifunctional nanoparticles containing a magnetic Fe3O4@SiO2 sphere and a biocompatible block copolymer poly(ethylene glycol)-b-poly(aspartate)(PEG-b-PAsp) were prepared.The silica coated on the superparamagne...Novel multifunctional nanoparticles containing a magnetic Fe3O4@SiO2 sphere and a biocompatible block copolymer poly(ethylene glycol)-b-poly(aspartate)(PEG-b-PAsp) were prepared.The silica coated on the superparamagnetic core was able to achieve a magnetic dispersivity,as well as to protect Fe3O4 against oxidation and acid corrosion.The PAsp block was grafted to the surface of Fe3O4@SiO2 nanoparticles by amido bonds,and the PEG block formed the outermost shell.The anticancer agent doxorubicin(DOX) was loaded into the hybrid nanoparticles via an electrostatic interaction between DOX and PAsp.The release rate of DOX could be adjusted by the pH value.展开更多
In this study, silicone-oil-based γ-Fe2O3 mag- netic fluid was successfully prepared by thermal oxidizing of Fe3O4 magnetic nanoparticles, which were prepared by chemical co-precipitation with FeSO4-7H2O and FeCl3- 6...In this study, silicone-oil-based γ-Fe2O3 mag- netic fluid was successfully prepared by thermal oxidizing of Fe3O4 magnetic nanoparticles, which were prepared by chemical co-precipitation with FeSO4-7H2O and FeCl3- 6H2O, and their surface was modified by oleate ligands. Silicone oil was used as carrier liquid and oleic acid was as surfactant for preparing γ-Fe2O3 magnetic fluid. It is found that the Fe3O4 nanoparticles surrounded by oleate ligands are not damaged during the thermal oxidizing. The shape of γ-Fe2O3 magnetic nanoparticles prepared is similar to spherical, and their mean size is about 10-20 nm, which has nothing obvious difference compared with Fe3O4. Thesaturation magnetization of γ-Fe2O3 magnetic fluid pre-pared is 14.25 A.me.kg-1 and that of γ-Fe2O3 nanoparti-cles is 57.56 A.m2.kg-1. The needle of γ-Fe2O3 magneticfluid is much bigger than that of Fe3O4 magnetic fluidunder the same magnetic field, which shows better mag-netic properties.展开更多
文摘The Fe3O4@SiO2 composite nanoparticles were obtained from as-synthesized magnetite (Fe3O4) nanoparticles through the modified St?ber method. Then, the Fe3O4 nanoparticles and Fe3O4@SiO2 composite nanoparticles were characterized by means of X-ray diffraction (XRD), Raman spectra, scanning electron microscope (SEM) and vibrating sample magnetometer (VSM). Recently, the studies focus on how to improve the dispersion of composite particle and achieve good magnetic performance. Hence effects of the volume ratio of tetraethyl orthosilicate (TEOS) and magnetite colloid on the structural, morphological and magnetic properties of the composite nanoparticles were systematically investi-gated. The results revealed that the Fe3O4@SiO2 had better thermal stability and dispersion than the magnetite nanoparticles. Furthermore, the particle size and magnetic property of the Fe3O4@SiO2 composite nanoparticles can be adjusted by changing the volume ratio of TEOS and magnetite colloid.
基金This work was supported by grants from the National Natural Science Foundation of China Key Program(NO.81530094)General Program(NO.81573574,81873193)the Science and Technology Development Project of Jilin Province(20190201283JC).
文摘Enrichment of trace bioactive constituents and metabolites from complex biological samples is challenging.This study presented a one-pot synthesis of magnetic polydopamine nanoparticles(Fe3O4@-SiO2@PDA NPs)with multiple recognition sites for the magnetic dispersive solid-phase extraction(MDSPE)of ginsenosides from rat plasma treated with white ginseng.The extracted ginsenosides were characterized by combining an ultra-high-performance liquid chromatography coupled to a highresolution mass spectrometry with supplemental UNIFI libraries.Response surface methodology was statistically used to optimize the extraction procedure of the ginsenosides.The reusability of Fe3O4@-SiO2@PDA NPs was also examined and the results showed that the recovery rate exceeded 80%after recycling 6 times.Furthermore,the proposed method showed greater enrichment efficiency and could rapidly determine and characterize 23 ginsenoside prototypes and metabolites from plasma.In comparison,conventional methanol method can only detect 8 ginsenosides from the same plasma samples.The proposed approach can provide methodological reference for the trace determination and characterization of different bioactive ingredients and metabolites of traditional Chinese medicines and food.
基金financially supported by the Shanghai Natural Science Foundation (No. 13ZR1400300)National Key R&D Program of China (No. 2017YFB030900)
文摘Novel magnetic core/shell bimetallic Au/Cu nanoparticles(Fe_3O_4@SiO_2-Au/Cu NPs) were prepared using SiO_2-coated iron oxide(Fe_3O_4@SiO_2) as a supported material. The magnetic Fe_3O_4 colloidal nanocrystal clusters(CNCs) as nano-core were modified with a silica coating for improvement stability and superficial area of the Au-Cu particles. The morphological structure and chemical composition of the Fe_3O_4@SiO_2-Au/Cu NPs were characterized with high-resolution transmission electron microscopy(HRTEM), energy-dispersive X-ray(EDX) and X-ray photoelectron spectroscopy(XPS) analyses. The Au and Cu NPs were deposited on the SiO_2 surface in a highly dense and well dispersed manner with an average size of approximately 5 nm. The Fe_3O_4@SiO_2-Au/Cu NPs as magnetic nano-catalysts were applied to the Ullmann coupling reaction of bromamine acid to synthesize 4,40-diamino-1,10-dianthraquinonyl-3,30-disulfonic acid(DAS). The prepared Fe_3O_4@SiO_2-Au/Cu NPs exhibited efficient catalytic activity with higher conversion and selectivity. A bromamine acid conversion of 97.35% and selectivity for DAS of 88.67% were obtained in aqueous medium. The magnetic nano-catalysts can be readily separated from the reaction system and reused. This new nano-catalytic reaction represents a useful and attractive cleaner production system. The new catalyst system has important and potential applications in dye and pigment industry.
基金supported by the National Natural Science Foundation of China (Grant Nos 20774051,50625310,and 50830103)the Opening Foundation of Sichuan University
文摘Novel multifunctional nanoparticles containing a magnetic Fe3O4@SiO2 sphere and a biocompatible block copolymer poly(ethylene glycol)-b-poly(aspartate)(PEG-b-PAsp) were prepared.The silica coated on the superparamagnetic core was able to achieve a magnetic dispersivity,as well as to protect Fe3O4 against oxidation and acid corrosion.The PAsp block was grafted to the surface of Fe3O4@SiO2 nanoparticles by amido bonds,and the PEG block formed the outermost shell.The anticancer agent doxorubicin(DOX) was loaded into the hybrid nanoparticles via an electrostatic interaction between DOX and PAsp.The release rate of DOX could be adjusted by the pH value.
基金financially supported by the National Natural Science Foundation of China (No.51274039)
文摘In this study, silicone-oil-based γ-Fe2O3 mag- netic fluid was successfully prepared by thermal oxidizing of Fe3O4 magnetic nanoparticles, which were prepared by chemical co-precipitation with FeSO4-7H2O and FeCl3- 6H2O, and their surface was modified by oleate ligands. Silicone oil was used as carrier liquid and oleic acid was as surfactant for preparing γ-Fe2O3 magnetic fluid. It is found that the Fe3O4 nanoparticles surrounded by oleate ligands are not damaged during the thermal oxidizing. The shape of γ-Fe2O3 magnetic nanoparticles prepared is similar to spherical, and their mean size is about 10-20 nm, which has nothing obvious difference compared with Fe3O4. Thesaturation magnetization of γ-Fe2O3 magnetic fluid pre-pared is 14.25 A.me.kg-1 and that of γ-Fe2O3 nanoparti-cles is 57.56 A.m2.kg-1. The needle of γ-Fe2O3 magneticfluid is much bigger than that of Fe3O4 magnetic fluidunder the same magnetic field, which shows better mag-netic properties.