Objective To investigate the effects of Lycii Fructus(LF,Gou Qi Zi,枸杞子)and Salviae Miltiorrhizae Radix Ex Rhizoma(SM,Dan Shen,丹参)on the syndrome of deficiency with blood stasis in the RCS(rdy-/-,p-/-)rats with re...Objective To investigate the effects of Lycii Fructus(LF,Gou Qi Zi,枸杞子)and Salviae Miltiorrhizae Radix Ex Rhizoma(SM,Dan Shen,丹参)on the syndrome of deficiency with blood stasis in the RCS(rdy-/-,p-/-)rats with retinitis pigmentosa(RP).Methods A total of 32 RCS(rdy-/-,p-/-)rats were divided into 4 groups(equal amounts of female and male rats in each group):model group treated with 0.9%normal saline,LF group treated with LF formula granules,SM group treated with SM formula granules,and LF and SM(L·S)group treated with LF and SM formula granules.Eight RCS(rdy+/+,p+/+)rats(4 males and 4 females)were treated with 0.9%normal saline to serve as blank group.The contents of E2,PG,P-Selectin,plasma viscosity,whole blood relative index of the high shear rate and fibrinogen content in plasma,and the content of cAMP and cGMP in retinal homogenate were detected.The retina was evaluated by hematoxylin-eosin staining.Results The contents of E2,PG,P-Selectin,plasma viscosity,whole blood relative index of the high shear rate,and fibrinogen content in the plasma of L·S group significantly differed from those of model group(P<0.01),but were similar to those of blank group.The contents of cAMP and cGMP in the retinal homogenate of L·S group significantly differed from those in model group(P<0.01)but were similar to those in blank group(P>0.05).Conclusions LF and SM can effectively treat retinitis pigmentosa by ameliorating the syndrome of deficiency with blood stasis.展开更多
目的:观察赵飞白经验方外治急性乳腺炎的疗效。方法:选取急性乳腺炎患者108例,随机分为治疗组和对照组,每组54例。所有患者均给予青霉素640万U加入5%葡萄糖500 m L中静脉滴注治疗,治疗组在以上治疗的基础上加用经验方外敷治疗。结果:治...目的:观察赵飞白经验方外治急性乳腺炎的疗效。方法:选取急性乳腺炎患者108例,随机分为治疗组和对照组,每组54例。所有患者均给予青霉素640万U加入5%葡萄糖500 m L中静脉滴注治疗,治疗组在以上治疗的基础上加用经验方外敷治疗。结果:治疗组有效率92.60%,对照组有效率77.78%,治疗组优于对照组(P<0.05);热毒炽盛证有效率优于气滞热壅证、正虚邪恋证(P<0.05)。结论:赵飞白经验方外治急性乳腺炎疗效显著,以热毒炽盛证疗效最好。展开更多
基金funding support from the National Natural science Foundation of China Funding Project (No. 81804150)Hunan Provincial Natural Science Funding Project (No. 2019JJ40226)+4 种基金National Key Discipline of TCM Diagnostics Foundation Funding Project (No. 2015ZYZD02)Hunan Provincial Department of Education Innovation Platform Open Funding Project (No. 16K065)Chinese Medicine Key Laboratory of Prevention and Treatment of Disease in Hunan Province (No. 2017TP1018)Hunan Engineering Technology Research Center for the Prevention and Treatment of Otorhinolaryngologic Diseases and Protection of Visual Function with Chinese Medicine (No. 2018TP2008)Changsha Science and Technology Plan Project
文摘Objective To investigate the effects of Lycii Fructus(LF,Gou Qi Zi,枸杞子)and Salviae Miltiorrhizae Radix Ex Rhizoma(SM,Dan Shen,丹参)on the syndrome of deficiency with blood stasis in the RCS(rdy-/-,p-/-)rats with retinitis pigmentosa(RP).Methods A total of 32 RCS(rdy-/-,p-/-)rats were divided into 4 groups(equal amounts of female and male rats in each group):model group treated with 0.9%normal saline,LF group treated with LF formula granules,SM group treated with SM formula granules,and LF and SM(L·S)group treated with LF and SM formula granules.Eight RCS(rdy+/+,p+/+)rats(4 males and 4 females)were treated with 0.9%normal saline to serve as blank group.The contents of E2,PG,P-Selectin,plasma viscosity,whole blood relative index of the high shear rate and fibrinogen content in plasma,and the content of cAMP and cGMP in retinal homogenate were detected.The retina was evaluated by hematoxylin-eosin staining.Results The contents of E2,PG,P-Selectin,plasma viscosity,whole blood relative index of the high shear rate,and fibrinogen content in the plasma of L·S group significantly differed from those of model group(P<0.01),but were similar to those of blank group.The contents of cAMP and cGMP in the retinal homogenate of L·S group significantly differed from those in model group(P<0.01)but were similar to those in blank group(P>0.05).Conclusions LF and SM can effectively treat retinitis pigmentosa by ameliorating the syndrome of deficiency with blood stasis.
文摘目的:观察赵飞白经验方外治急性乳腺炎的疗效。方法:选取急性乳腺炎患者108例,随机分为治疗组和对照组,每组54例。所有患者均给予青霉素640万U加入5%葡萄糖500 m L中静脉滴注治疗,治疗组在以上治疗的基础上加用经验方外敷治疗。结果:治疗组有效率92.60%,对照组有效率77.78%,治疗组优于对照组(P<0.05);热毒炽盛证有效率优于气滞热壅证、正虚邪恋证(P<0.05)。结论:赵飞白经验方外治急性乳腺炎疗效显著,以热毒炽盛证疗效最好。
