Study on Female Sexual Dysfunction in Type 2 Diabetic Chinese Women

Abstract Objective To investigate the female sexual dysfunction （FSD） in type 2 diabetes patients, by comparing the sexual function between type 2 diabetic women and non-diabetic women with Female Sexual Function Index （FSFI）. Methods 215 type 2 diabetic women and 107 age-matched non-diabetes women were enrolled with similar backgrounds. Their sexual functions were evaluated with FSFI. Metabolic parameters such as body mass index, blood lipid profile, hemoglobin AlC, plasma glucose were also collected. Results Total score of FSFI of the type 2 diabetic women were significantly lower than that of the non-diabetic controls （18.27±8.96 vs. 23.02±5.78, P=0.000）. Scores of the FSFI domains （desire, arousal, lubrication, orgasm, satisfaction, pain） of the type 2 diabetic group were also lower than those of the control group. According to the FSD criterion （FSFI〈25） available in China, the percentage of FSD in the type 2 diabetic group was significantly higher than that of the control group （79.2% vs. 55.0%, P〈0.001）. These trends seemed more prominent in pre-menopause subgroups. The logistic regression analysis indicated that age and diabetes were independent risk factors of FSD. Body Mass Index （BMI） also had influence in the diabetes group. Conclusion Findings from this study showed that there are more FDS in Chinese type 2 diabetic women than in their non-diabetic counterparts, especially in pre-menopause participants.

Female Sexual Dysfunction among Chinese Primiparous Women

Objective: To compare sexual function between primiparous women who underwent cesarean section (CS) and those who delivered vaginally. Methods: This cross-sectional study was conducted from October 2011 to April 2012 in Beijing, China. The target population included women aged 18 - 45 years who had given birth only once at least 6 months prior. The questionnaire was self-administered including female sexual function measured using the Female Sexual Function Index (FSFI). Data were analyzed using R software with the significance level of 0.05. Results: A total of 1456 participants were included and 102 women (7.0%) declined. The median age of the participants was 35 years. The median time interval after childbirth was 6 years. The median FSFI score was 26.9 and prevalence of female sexual dysfunction (FSD) was 34.2%. Both the FSFI scores and the proportions of individuals with sexual disorders were similar between women undergoing CS and those having vaginal delivery for both individual domains and the full scale. Conclusion: There were insignificant differences in female sexual function scores and FSD prevalence between women undergoing CS versus vaginal delivery.

Relationship between Female Sexual Function and Depression or Anxiety in Japan

Background: Sexual dysfunction is sexual complaints or disorders. There are various causes, but the onset leads to deterioration of relationships and quality of life with partners. There is still a deep-rooted awareness that sexuality is a secret in Japan. Aim: This study aims to clarify the relationship between female sexual function and depression or anxiety. Method: Four hundred and fifty-eight Japanese healthy women who worked in four randomly selected medical institutions in Okinawa Prefecture in Japan from March to May 2012 were asked to agree to a consent form of their own free will and participate in self-reported questionnaires. For their evaluation, the Female Sexual Function Index (FSFI;Rosen et al. 2000, which includes the six domains of desire, arousal, lubrication, orgasm, pain, and satisfaction) and the Kessler Psychological Distress Scale (K6;Kessler, 2002, which includes the following six items: felt nervous, hopeless, restless or fidgety, worthless, depressed, and felt that everything was an effort) was used. Moreover, participants’ characteristics showed age, marriage, menopause, annual income, and drinking. In addition, JMP16.2 and R 4.2.0 was used to perform Pearson’s chi-square test, Fisher’s exact test, Mann-Whitney U test, Kruskal-Wallis test, Steel-Dwass test, Spearman’s Rank-Order Correlation, and Cronbach’s alpha. This study was approved by the university and the medical institutional review board (IRB). Results: 178 women were included in the final analysis, and the median (IQR, interquartile range) was 39 (32 - 48) years old, and the mean ± SD (standard deviation) was 40.2 ± 10.4 years old. The median (IQR) and mean ± SD of FSFI Total Score were 22.0 (9.3 - 26.6) and 19.2 ± 9.6. The median (IQR) and the mean ± SD of K6 Total Score were 3 (0 - 7) and 4.2 ± 4.5. 16% of all women with a K6 Total Score of 10 and more, and 5% of all women with a K6 Total Score of 13 and more considered a serious mental illness. There was no clear association between female sexual function and depression or anxiety in all health worker participants between FSFI Total Score and K6 Total Score by Spearman’s Rank-Order Correlation Coefficient (ρ). However, there was a moderate correlation between the K6 Total Score and the FSFI Total Score in health worker participants with a K6 Total Score of 11 or more (n =19, ρ = ?0.62, P = 0.005). Moreover, there was a weak correlation between them in both married and drinking women or married and non-menopausal women. In the Mann-Whitney U test where few participants had morbid depression, significant relationships were found in the association between a sexual function with high depression or anxiety, whereas the low group had a K6 cut-off value of 11. Conclusion: Female sexual morbidity for high depression or anxiety should be managed with interventions. Especially, the intervention for decreasing female sexual function in the K6 Total Score of 11 or more will be needed, and a randomized study is required for more evidence.

Sexual Function in Pregnant Women in the Public Health System

Introduction: Pregnancy is a unique situation and involves changes in sexuality. The aim is to evaluate sexual function and satisfaction in pregnant women under prenatal care provided by the public health system. Method: Cross-sectional study with pregnant women receiving ambulatory care in the public health system in the Southern region of Brazil conducted between November 2014 and September 2015. Results: 283 pregnant women were studied. The mean age was 27.7 ± 6.3 years;64% were white and 31.1% were nulliparous. In the total sample, 8.50% were in the first trimester of pregnancy, 37.4% were in the second trimester, and 54.1% were in the third trimester. The rate of global sexual dysfunction (score 26 points) was 55.5%, following the application of The Female Sexual Function Index (FSFI). Sexual dysfunction was significantly more prevalent in the third trimester (62%) compared to the first (33.3%) and second (50.9%) trimesters (p = 0.015). There was a significant difference in all domains, except in the desired domain, according to the trimester. Pregnant women in the third trimester showed significantly lower scores compared to those in the first trimester in the domains with significance. Conclusion: The prevalence of sexual dysfunction among pregnant women in the public system was high. Knowing that more than 50% of the pregnant women presented sexual dysfunction, it is essential to approach sexuality during prenatal care involving the couple.

Sexual dysfunctions and their treatment in liver diseases

Sexual dysfunction(SD)is a prevalent but very commonly ignored aspect in the treatment of liver diseases and cirrhosis.The etiology of SD is multifactorial and therefore treatment strategies are complex,especially in females.Phosphodiesterase inhibitors are useful and effective in erectile dysfunction in males but in females,no single drug is available for SD,therefore multimodal treatment is required depending upon the cause.The foremost and fundamental requirement in both genders is to be stress-free and have adequate control of liver diseases.Improved quality of life is helpful in improving SD and vice versa is also true.Therefore,patients suffering from liver diseases should come forward and ask for treatment for SD,and physicians should actively enquire about SD while history taking and evaluating these patients.SD results in deterioration of quality of life,and both are modifiable and treatable aspects of liver diseases,which are never addressed actively,due to social taboos and fears of SD treatment in the presence of liver diseases.The diagnosis of SD does not require costly investigations,as the diagnosis can be established based on validated questionnaires available for both genders,therefore detailed targeted history taking using questionnaires is essential.Data are emerging in this area but is still at an early stage.More studies should be dedicated to SD in liver diseases.

长期使用不同给药方式的雌激素对绝经泌尿生殖道综合征的疗效及安全性分析

目的 探讨长期使用不同给药方式的雌激素对绝经泌尿生殖道综合征的疗效及安全性情况。方法 选取北京市顺义区妇幼保健院2019年2月至2022年1月收治的绝经泌尿生殖道综合征患者95例为研究对象,采用随机纸片法分为两组,治疗A组45例,经口服给药雌激素治疗,治疗B组50例,经阴道给予结合雌激素乳膏治疗。比较两组患者治疗前、治疗6个月后阴道症状评分、性交痛症状评分、女性性功能量表(FSFI)、阴道健康指数评分(VHIS)、尿失禁影响程度(IIQ-7)评分。比较两组患者临床症状加重、泌尿生殖道出血、泌尿生殖道感染、乳腺胀痛发生情况。结果 治疗前,两组患者阴道症状评分、性交痛症状评分、FSFI、VHIS、IIQ-7比较,差异均无统计学意义(P> 0.05);治疗6个月后,两组患者阴道症状评分、性交痛症状评分均低于同组治疗前,治疗B组IIQ-7低于同组治疗前,FSFI、VHIS均高于同组治疗6个月后,治疗B组阴道症状评分、性交痛症状评分、IIQ-7均低于治疗A组,FSFI、VHIS均高于治疗A组,差异有统计学意义(P <0.05)。两组患者临床症状加重、泌尿生殖道感染发生率比较,差异无统计学意义(P> 0.05);治疗B组患者泌尿生殖道出血、乳腺胀痛发生率低于治疗A组,差异有统计学意义(P <0.05)。结论 经阴道给予结合雌激素乳膏治疗绝经泌尿生殖道综合征患者,可以改善患者临床症状、提高性功能,安全性高,值得临床推广应用。

非手术治疗产后性功能障碍的研究进展

产后性功能障碍(postpartum sexual dysfunction,PSD)是女性发病率较高的疾病,病因复杂,治疗方法多样,包括心理治疗、药物治疗、行为治疗、物理康复治疗和手术治疗等,目前PSD主要治疗措施仍是非手术治疗。盆底科医生应对产后女性恢复性生活过程中遇到的问题给予专业指导;药物治疗可有效缓解阴道干燥和灼热感;电刺激和生物反馈均可减轻性交痛,且生物反馈比电刺激在提高性欲、增加阴道润滑度方面更有优势;磁刺激不仅能提升盆底肌力,对产后性交痛也有一定疗效;盆底肌筋膜痛手法治疗则需要与其他治疗方式联合应用;射频治疗多用于改善阴道松弛及干涩。综述PSD非手术治疗中的干预措施及其适应证并评价其治疗效果,为探寻PSD的最佳非手术治疗方法提供可靠临床依据。

Prevalence and Factors Associated with Female Sexual Dysfunction in Beijing, China

Background： Female sexual dysfunction （FSD） is a highly prevalent and often underestimated problem. However, large-scale, population-based epidemiological surveys of FSD are scarce in China. The present study was conducted to evaluate the prevalence and the potential risk factors of FSD across a selection of social groups in Beijing, China, based on the Female Sexual Function Index （FSFI）. Methods： A cross-sectional study based on the multiple-stage cluster sampling was performed with adult women throughout the Dongcbeng and Shunyi districts of Beijing. The Chinese version of FSFI was used, as well as questions on demographic characteristics, the disease-related context, and social relationships. Results： A total of 6000 consecutive women entered this study, with an actual response from 5024 women, corresponding to a response rate of 83.7%. A total of 4697 （78.3%） questionnaires were effective. The prevalence of adult FSD in Beijing was 2973 （63.3%） using a score of 26.55 as the boundary value, whereas the total mean FSFI score was 23.92 ~ 6.37. However, 1423 （30.3%） women did not seek help. By multivariate logistic regression analysis, the possible potential risk factors included age （odds ratio [OR] = 1.051 ）, dissatisfaction with the spouse＇s sexual ability （OR = 3.520）, poor marital affection （OR = 2.087）, spouse sexual difficulties （OR = 1.720）, dissatisfaction with married life （OR = 1.476）, living in a rural area （OR = 1.292）, chronic pelvic pain （OR = 1.261）, chronic disease （OR = 1.534）, previous pelvic surgery （OR = 1.605）, vaginal delivery （OR = 2.285）, lower education （OR = 3.449） and postmenopausal （OR = 3.183）. Conclusions： As suggested by the FSFI scores, female sexual problems are highly prevalent in Beijing. Dissatisfaction with the spouse＇s sexual ability, poor marital affection, sexual difficulties of the spouse, dissatisfaction with the marriage, rural life, CPP, and postmenopausal were conceivable risk factors for FSD in Beijing women.

女性性功能指数的使用现状

本文介绍女性性功能指数(FSFI)量表的使用现状、使用注意事项和评分计算方法。

北京及周边地区围绝经期女性性功能现状调查分析

目的调查中国北京周边地区围绝经期女性性功能障碍的患病率和患病类型,分析围绝经期女性性功能的影响因素。方法采用横断面研究方法,使用女性性功能指数量表(Female Sexual Function Index,FSFI)和Kupperman评分量表和自制量表对北京及周边地区围绝经期女性进行问卷调查,并分析和探讨调查结果。结果共发放407份问卷,回收308例有效问卷进入统计学分析,有效回收率75.6%。北京周边地区围绝经期女性性功能障碍总体发病率为84.1%,性欲障碍、性唤起障碍、阴道润滑、性高潮、性交痛和性满意度发生率分别为95.5%、69.8%、60.7%、66.9%、69.5%和69.2%。不同年龄组围绝经期女性在性欲障碍、性唤起障碍、阴道的润滑度、性高潮障碍、性满意障碍以及性交痛等6个维度的得分差异有统计学意义(P<0.05)。结论影响围绝经期女性性功能的主要因素有年龄、绝经、激素补充、经济水平和身体健康状况。

成都市女性性功能障碍的调查与相关因素的探析

目的:对成都市区FSD的患病情况进行调查,并探寻可能对其造成影响的相关因素。方法:以2015年7月至12月于四川大学华西医院健康体检中心进行体检的女性作为调查对象,应用中文版女性性功能指数量表(CVFSFI)及Beck抑郁问卷第二版(BDⅠ-Ⅱ)进行问卷调查,应用SPSS19.0建立数据库进行统计分析。结果:本次研究共发放问卷1237份,回收完整填写问卷1116份(回收率为90.2%)。女性性功能障碍(FSD)的发生率为26.1%,6个维度出现问题的比例由高到低依次为:性交疼痛23.4%,性满意度低22.6%,性高潮障碍21.5%,阴道润滑困难19.1%,性欲低下17.2%,性唤起困难15.9%。总体CVFSFI平均总分为(25.756±3.878)分。CVFSFI总分及6个维度的得分随着年龄的增长而减小。各个年龄组FSD发生率分别为:20~29岁组16.7%;30~39岁组21.9%;40~49岁组24.6%;≥50岁组64.7%。不同年龄组间,FSD发生率及各维度出现问题的比例差异均有统计学意义(P均<0.001),且随着年龄的增长有明显的增加。多因素Logistics回归分析显示,受教育(OR=0.654)是FSD的保护因素;年龄(OR=1.042)、BMI(OR=1.073)、绝经(OR=3.498)以及抑郁(OR=1.033)为FSD的危险因素。结论:成都市女性发生性功能障碍的比例约为26.1%,其中性交疼痛和性满意度低为主要表现。分析得出女性发生性功能障碍可能与年龄、BMI较大,受教育水平较低,以及处于绝经、抑郁状态有关。

妇科良性疾病与女性性功能障碍相关性分析

目的探讨妇科良性疾病与女性性功能障碍(FSD)相关性,为防治FSD的发生及防治提供理论依据。方法采用横断面调查方法,选取中等收入城市及农村居民区20岁及其以上女性进行问卷调查,收集其人口学特征及目前所患妇科疾病(经诊断确诊过的疾病)等信息。采用中文版女性性功能量表(FSFI)进行FSD评估,总分小于26.55说明存在FSD。应用多因素非条件Logistic回归模型分析妇科良性疾病与FSD相关性。结果发放问卷1 130份,收回1 068份(回收率94.5%),去除不符合要求问卷80份,共纳入有效问卷988份。988例被访者中妇科良性疾病患者占39.8%(393/988),为患病组,其余为健康组。393例患者中,性功能障碍者占71.2%(280/393),高于健康组性功能障碍患病率(P<0.05)。与健康组相比,患病组在总分及性欲、性唤起、性高潮方面的评分分值均较健康组低(P<0.05)。多因素非条件Logistic回归分析显示,妇科良性疾病、年龄(≥40岁)及绝经是FSD的独立危险因素,较高的教育水平是其保护性因素。结论 FSD是一个重要的公共卫生问题,甘肃省在妇科良性疾病者中FSD现患率较高,应加强性健康教育,降低FSD发生率。

多囊卵巢综合征女性性功能与性激素和甲状腺激素的相关性

目的分析多囊卵巢综合征(PCOS)患者的性功能与性激素及甲状腺激素的相关性。方法采用横断面研究方法,对2019年1~12月就诊北京妇产医院妇科内分泌科的PCOS患者,使用女性性功能指数量表(female Sexual Function Index,FSFI)评估性功能;测量其基本体质指标并测定基础血清性激素水平,包括卵泡刺激素(FSH)、黄体生成素(LH)、催乳素(PRL)、总睾酮(TT)及性激素结合球蛋白(SHBG);检测甲状腺功能,包括促甲状腺激素(TSH)、总三碘甲状腺原氨酸(TT3)、游离三碘甲状腺原氨酸(FT3)、总甲状腺激素(TT4)、游离甲状腺激素(FT4)水平。分析基本体质指标、性激素水平及甲状腺功能指标与FSFI评分的相关性。结果共有234例PCOS女性纳入统计分析,FSFI总分平均值为(24.21±2.93),79.06%的患者被认为有性功能障碍高风险(cut-off值26.55)。斯皮尔曼相关性分析显示,年龄、BMI、腰围、腰臀比与FSFI得分呈负相关(P<0.05);总睾酮与性满意度得分呈负相关(r=-0.213,P=0.041),游离雄激素指数(FAI)与性高潮得分呈正相关(r=0.167,P=0.035);TSH与性欲及阴道润滑得分呈负相关(分别为r=-0.162,P=0.032;r=-0.185,P=0.017),FT4与FSFI总分呈正相关(r=0.223,P=0.031)。其余性激素和甲状腺激素及SHBG、PRL与FSFI得分之间未显示显著相关性(P>0.05)。结论PCOS患者的性功能与雄激素水平及甲状腺功能有关,临床诊疗中对PCOS患者的高雄激素及甲状腺功能异常应予以重视和管理。

苓芍枣仁配方颗粒联合酒石酸托特罗定治疗女性膀胱过度活动伴性功能障碍临床观察

目的:初步评价苓芍枣仁配方颗粒联合酒石酸托特罗定治疗青年女性膀胱过度活动症伴性功能障碍患者的临床疗效。方法:选择2017年4月至2017年11月中国中医科学院西苑医院泌尿外科门诊治疗的符合膀胱过度活动症诊断(膀胱过度活动症状评分问卷(OABSS)总得分≥3分,尿急症状得分≥2分。)年龄范围26岁～40岁的女性、有性生活史、女性性功能指数(FSFI)<25分、病程≥3个月例的患者10例。给予酒石酸托特罗定缓释片,每日一次,每次1片。同时配合口服苓芍枣仁配方颗粒。每天2次,每次1袋,连续治疗4周。比较10例患者治疗前后的OABSS评分、女性性功能指数(FSFI)评分。结果:治疗4周后10例患者的OABSS评分总分、尿急评分、尿失禁评分、FSFI评分总分,和治疗前相比较,差异具有统计学意义(P <0. 001)。其中FSFI评分中的性高潮评分和治疗前相比较,差异无统计学意义(P=0. 03)。性欲评分、性兴奋评分、阴道润滑评分、性交疼痛评分、性满意度评分和治疗前相比较,均有显著升高,差异具有统计学意义(P <0. 05)。结论:苓芍枣仁配方颗粒联合酒石酸托特罗定缓释片不仅可以缓解患者的尿频、尿急症状,也具有对患者的性功能障碍存在治疗作用。

妇科恶性肿瘤患者治疗后性生活状况的研究

目的:研究妇科恶性肿瘤患者治疗后性生活状况及保留卵巢对性生活的影响。方法:对110例北京大学第一医院收治的妇科恶性肿瘤手术、放化疗后3个月以上的女性进行问卷调查,并比较保留卵巢组和卵巢缺失组间性生活状况的差异。结果:110例患者中子宫内膜癌31例、卵巢恶性肿瘤38例、宫颈癌41例,不同肿瘤治疗后女性性功能指数量表(FSFI)性欲评分中位数的差异具有统计学意义(P=0.042)。保留卵巢组与卵巢缺失组治疗后性生活恢复时间及FSFI各项评分的影响的差异均有统计学意义。结论:妇科恶性肿瘤患者治疗后性生活质量明显下降,保留卵巢对妇科肿瘤患者性生活恢复有重要意义,严格掌握卵巢切除适应症,重视对患者性健康教育,有助于提高患者性生活质量。

口服避孕药对多囊卵巢综合征患者性功能的影响

目的评估口服避孕药(oral contraceptives,OCs)对多囊卵巢综合征(polycystic ovary syndrome,PCOS)患者性功能的影响,并分析其女性性功能障碍(female sexual dysfunction,FSD)发生的危险因素。方法研究共纳入210例门诊PCOS患者,其中服用口服避孕药者126例(OC组),未服用者84例(NOC组)。采用网络女性性功能指数(Female Sexual Function Index,FSFI)量表,并补充附加问题,评估参与者的基本信息、避孕方法、性伴侣关系稳定程度、孕产史等多个女性性功能的潜在影响因素。结果OC组FSFI总分中位数为26.35分,50.79%表现为FSD高风险;NOC组FSFI总分中位数26.85分,47.62%显示FSD高风险;两组得分相比差异无统计学意义(P=0.635)。在口服避孕药使用者中,服用35μg炔雌醇/2 mg醋酸环丙孕酮、30μg炔雌醇/3mg屈螺酮、30μg炔雌醇/150μg去氧孕烯三种不同成分口服避孕药的患者之间,FSFI得分差异无统计学意义。经Logistic回归分析,性生活是否主动、伴侣关系是否稳定是PCOS患者性功能的影响因素。结论 PCOS患者中,是否服用口服避孕药、服用不同类型口服避孕药的患者之间性功能评分差异均无统计学意义。PCOS患者性功能的潜在影响因素中,性生活是否主动、伴侣关系是否稳定与FSD高风险的发生相关。

多囊卵巢综合征女性性功能现状及性功能障碍的危险因素调查分析

目的:调查多囊卵巢综合征(polycystic ovary syndrome,PCOS)患者的性功能现状,探讨PCOS女性性功能障碍(female sexual dysfunction,FSD)的危险因素。方法:采用横断面研究方法,对首都医科大学附属北京妇产医院(我院)内分泌科2019年1—12月就诊的PCOS患者使用女性性功能指数(Female Sexual Function Index,FSFI)量表,并补充附加问题,年龄、身高、体质量、腰围、臀围、高雄激素临床表现、学历、职业分类、收入水平、避孕、怀孕意愿、生活及工作压力和有氧运动等多个可能影响女性性功能的因素进行问卷调查。结果:本次调查共发放946份调查问卷,回收有效问卷712份(75.26%)。PCOS患者的FSFI总分平均(24.19±2.87)分,取Cut-off值为26.55分时,566例(79.49%)为FSD高风险者。选取各维度的最大值的33%为Cut-off值,阴道润滑障碍、性高潮障碍、性欲障碍、性交痛障碍、性唤起障碍和性满意度障碍的高风险者分别为67例(9.41%)、38例(5.34%)、19例(2.67%)、17例(2.39%)、12例(1.69%)和3例(0.42%)。多重线性回归分析显示,怀孕意愿、避孕、体质量指数(BMI)、高雄激素临床表现、年龄是PCOS女性性功能障碍的相关因素。结论:PCOS患者是FSD的高危人群,对于怀孕意愿、肥胖、高雄激素临床表现、年龄增加等危险因素应该予以重视和管理。

肾移植后生育期女性的月经、性生活及生育状况

背景:理论上讲成功的肾移植可以使生育年龄段女性月经正常化,性生活明显改善,肾移植后可以生育,但国内报道不多。目的:通过自制的"生育年龄段女性肾移植后的月经、性生活、生育状况调查表"并配合生活质量评分表、女性性功能指标量表调查不同生育年龄段女性肾移植前后月经、性生活及移植后生育状况,探讨其影响因素。方法:选择2006年1月至2011年12月在长征医院施行肾移植的生育年龄段患者68例,依据年龄段分为低年组(n=41)和中年组(n=27),以自制的"生育年龄段女性肾移植后的月经、性生活、生育状况调查表"并配合生活质量评分表、女性性功能指标量表进行门诊和电话随访,观察两组患者移植后3年与血液透析期的月经、性生活、生育状况,并分析其影响因素。结果与结论:54例在肾移植后(3.46±1.23)个月月经改善(低年组38例,中年组16例),11例改善不明显(低年组3例,中年组8例),3例较透析前恶化(低年组0例,中年组3例),其中因月经量过多2例行诊刮术,1例行宫腔镜止血术;45例在肾移植后(3.43±1.27)个月性生活改善(低年组34例,中年组11例),11例无明显改善(低年组2例,中年组9例),12例移植后无性生活史(低年组5例,中年组7例)。7例肾移植后(30.24±7.86)个月受孕(低年组5例,中年组2例),其中2例生育子女(均为低年组),5例流产。通过患者肾移植后及移植前进行SF-36量表的调查比较,发现受者在躯体功能、生理职能、躯体疼痛、总体健康、活力领域分值均较移植前明显升高(P<0.05),但在情感职能、心理健康及社会功能领域分值与移植前比较,差异无显著性意义(P>0.05)。肾移植后与肾移植前患者FSFI量表评分比较,发现肾移植后患者性生活质量各指标中,性欲望、性兴奋、阴道润滑、高潮、满意度分值升高,疼痛分值下降,差异均有显著性意义(P<0.05)。结果可见年龄较大受者月经、性生活状况改善也不明显,在严密监护并认真掌控受孕标准的情况下,女性肾移植受者妊娠是可行、安全的。

医院就诊女性患者性功能障碍调查(附420例资料分析)

目的总结在我院就诊的女性患者性功能障碍的患病率和患病类型,探讨其影响因素。方法选取420例就诊于北京妇产医院内分泌科的围绝经期女性及女性家属,采用女性性功能指数量表(female sexual function in-dex,FSFI)和自制量表进行问卷调查,并进行统计学分析。结果本组女性患者性功能障碍总体发病率为84.1%,性欲障碍、性唤起障碍、阴道润滑、性高潮、性交痛和性满意度发生率分别为95.5%,69.4%,57.9%,66.9%,68.5%和69.1%。不同年龄、月经情况、收入及是否有合并症/激素补充治疗女性性功能FSD发生率差异均有统计学意义(P<0.05)。结论影响女性性功能的主要因素有年龄、绝经、激素补充、经济水平和身体健康状况。

无精子症患者配偶性生活质量的探讨

目的探讨无精子症患者配偶的性生活质量。方法选择自愿接受性生活质量问卷调查的64例不孕女性,按其男方精液质量进行分组,无精子症组28例为研究组,精液正常因输卵管因素就诊者36例为对照组,调查2组配偶性生活质量及男性性功能状况。结果 64例女性性生活质量与职业及文化程度无关,无精子症组配偶性生活总体满意度、同房时间低于对照组,差异有统计学意义(P<0.05);同房频率、性冷淡发生率高于对照组,差异有统计学意义(P<0.05)。结论无精子症患者配偶性生活满意度相对较低,应积极改善不孕不育患者性心理状况。