The Relation of Fetal Colon Diameter with Estimation of Gestational Age

Background: Conventional ultrasound dating is not very accurate after 34 weeks of gestation and has standard deviation of about 2 weeks. Objective: Verify whether fetal colon diameter can be used as a tool for estimating gestational age (GA) of fetuses between 34 to 40 weeks. Materials and Methods: This was a prospective cross-sectional study conducted at Obstetrics and Gynecology University Hospital, Damascus, Syria, during the period from September 2019-September 2020. The study enrolled 395 women with uncomplicated singleton pregnancies at 34 - 40 weeks of gestation. Fetal bi-parietal diameter, head circumference, abdominal circumference, and femoral lengths were assessed by ultrasound. In addition, descending colon diameter was assessed at the level of colonic haustra. The correlation between GA and colon diameter was assessed by the Pearson correlation test. Results: Significant correlation between fetal colon diameter and gestational age was observed P < 0.0001 (r = 0.852). In addition, a highly significant correlation between colon diameter and bi-parietal diameter, femoral length, head circumference and abdominal circumference were found with P values < 0.0001. The correlation between gestational age at 3rd trimester and colon diameter was significantly stronger than the correlation between gestational age and bi-parietal diameter, head circumference, and abdominal circumference. Whereas, no significant difference was found when comparing colon diameter and femoral lengths (P = 0.089). Conclusion: The present study suggested that colon diameter can be used for predicting third trimester gestational age.

超声评估子痫前期患者胎儿成熟度的预测方法及其对临床的指导价值

目的探讨超声评估子痫前期患者其胎儿成熟度,超声评估子痫前期患者胎儿成熟度的预测方法及其对临床的指导价值。方法选取子痫前期患者102例,均行剖宫产提前分娩终止妊娠,根据早产儿的体质量分为≥2 kg组66例(A组)和<2 kg组36例(B组)。比较分析两组孕期超声检查的各项指标,并根据早产儿是否需要进入保暖箱治疗为标准建立超声测量参考值。结果 A组早产儿均未进入保暖箱治疗,其中双顶径≥80 mm者占92.4%,股骨长度≥63 mm者占95.5%,结肠宽度≥9 mm者占90.9%,胎肺回声高于胎肝回声者占97.0%。B组早产儿均进入保暖箱治疗,其中双顶径<80 mm者占86.1%,股骨长度<63 mm者占94.4%,结肠宽度<9 mm者占91.7%,胎肺回声低于胎肝回声者占97.2%。无需进入保暖箱治疗的早产儿其超声特征至少具备下列条件中的三项:胎儿双顶径≥80 mm,股骨长度≥63 mm,结肠宽度≥9 mm,内可见胎粪或气体回声,胎肺回声高于胎肝回声。结论通过超声检查胎儿双顶径、股骨长度、胎肺与胎肝回声、结肠宽度,可直观准确掌握胎儿宫内发育成熟情况,为临床提高早产儿存活率及生存质量提供指导。

人胚结肠亮氨酸－脑啡肽的分布

本文用免疫细胞化学技术（ＩＣＣ）对３个月人胚结肠亮氨酸－脑啡肽（Ｌ－ＥＮＫ）的分布，来源及性质进行了观察。结果表明：人胚结肠在肌层、粘膜下层和粘膜层均有Ｌ－ＥＮＫ免疫反应性神经分布，在肌间神经丛可见成层排列的Ｌ－ＥＮＫ神经元细胞体，由其发出的神经纤维由环肌层向粘膜方向投射。上述分布特征说明，Ｌ－ＥＮＫ神经可能与结肠的运动和腺体的分泌调节有关。