Introduction Herpes zoster is a skin disease caused by activation of the varicella zoster virus,which is latent in neurons.It can be accompanied by severe neuralgia.Some herpes zoster patients may have pain allergy,ge...Introduction Herpes zoster is a skin disease caused by activation of the varicella zoster virus,which is latent in neurons.It can be accompanied by severe neuralgia.Some herpes zoster patients may have pain allergy,general discomfort,loss of appetite and other prodromal symptoms,typical clinical manifestation as a cluster of blisters distribution along unilateral peripheral nerve,often accompanied by obvious neuralgia[1].展开更多
Objective:To evaluate the effectiveness and safety of fire needling for herpes zoster from randomized clinical trials (RCTs).Methods:We searched Cochrane Central Register of Controlled Trials,Pubmed,Sino-Med,CNKI,VIP,...Objective:To evaluate the effectiveness and safety of fire needling for herpes zoster from randomized clinical trials (RCTs).Methods:We searched Cochrane Central Register of Controlled Trials,Pubmed,Sino-Med,CNKI,VIP,WanFang databases,and conference proceedings to November,2017.RCTs were eligible if they tested fire needling for treating herpes zoster more than 3 times.Two authors screened all references,assessed the risk of bias,extracted data,independently,and analyzed data using Trial Sequential Analysis (TSA).Treatment effects were presented as risk ratio (RR)for binary data and standardized mean difference (SMD) for continuous data with 95% confidence interval (CI).Results:We included 27 RCTs with a total of 1933 participants.Only one RCT had low risk of bias,and the others were of high or moderate risk of bias.For total effectiveness rate (proportion of total number of people who were cured or significant symptom improved),there was no significant difference between Western medicine (acyclovir,valacyclovir,adenosine cobalamin) and fire needling (risk ratio 1.05,95% CI 0.98 to 1.12;n =5).For pain relief (VAS scale):fire needling used alone showed lower scores than Western medicine (SMD-1.37,95% CI-1.77 to-0.97;n =2) or external medicine (diclofenac) (SMD-2.23,95% CI-2.81 to-1.64;n =1).Combination of fire needling and Western medicine was better than Western medicine alone in relieving pain (VAS scale) (SMD-2.19,95% CI-3.40 to-0.97,I2 =94%;n =4).Patients receiving fire needling had lower incidence of neuralgia than those receiving Western medicine (3.3% vs 26.7%,RR 0.09,95% Cl 0.01 to 0.82;n =1) at follow up for 30 days.No serious adverse events such as infection were reported.Conclusion:Fire needling appears to offer relief for alleviating pain in herpes zoster.As the sample size of included trials was small and the quality of studies was generally low,rigorous clinical trials with robust reporting and appropriate outcome measures are still needed.展开更多
Objective:To compare the effectiveness of fire needle versus Western medicine in the treatment of herpes zoster.Methods:Randomized controlled trials comparing fire needle with Western medicine in the treatment of herp...Objective:To compare the effectiveness of fire needle versus Western medicine in the treatment of herpes zoster.Methods:Randomized controlled trials comparing fire needle with Western medicine in the treatment of herpes zoster were identified using 8 databases.A meta-analysis was performed using RevMan 5.3 software.Results:Eight trials involving 569 patients were included in this meta-analysis,and the results showed that fire needle was superior to Western medicine comparing the effective rate[risk ratio(RR)=1.13,95%confidence interval(Cl):1.06 to 1.20;P=0.0002],the visual analog scale(VAS)score[mean difference(MD)=-7.95;95%Cl:-10.71 to-5.20;P<0.00001],time of pain disappearance(MD=-7.61;95%CI:-9.38 to-5.84;P<0.00001),time of blister-stop(MD=-1.34,95%CI:-1.51 to-1.18;P<0.00001),time of crusted scab(MD=-2.92,95%CI:-3.62 to-2.23;P<0.00001);and time of scab off(MD=-4.64,95%CI:-5.83 to-3.46;P<0.00001).In addition,a significantly lower incidence of postherpetic neuralgia was found in the fire needle group in 30 d(RR=0.23,95%CI:0.11 to 0.51;P=0.0002)and 60 d(RR=0.33,95%CI:0.12 to 0.91;P=0.03)after treatment.Conclusion:Fire needle has a favorable effect in increasing the effective rate,relieving pain,recovering skin lesions and decreasing incidence of postherpetic neuralgia in the treatment of herpes zoster.However,considering the limitations in this study,the findings should be interpreted cautiously.展开更多
In recent 2 years, the author used a three-edged needle to scratch the vesicles for treatment of herpes zoster and obtained good therapeutic results as reported in the following. General Data 21 cases were observed in...In recent 2 years, the author used a three-edged needle to scratch the vesicles for treatment of herpes zoster and obtained good therapeutic results as reported in the following. General Data 21 cases were observed in this series, including 12 males and 9 females, with ages ranging from 4 to 72 years. The shortest disease course was 1 day and the longest. 2 weeks. Clinical Manifestations There were 15 cases with groups展开更多
Objective:To discuss the effectiveness and safety of swift needling with fire needle plus medication in treating herpes zoster and the change of substance P.Methods:Seventy-nine patients with herpes zoster were select...Objective:To discuss the effectiveness and safety of swift needling with fire needle plus medication in treating herpes zoster and the change of substance P.Methods:Seventy-nine patients with herpes zoster were selected and randomized into a fire-acupuncture group(41 cases)and a Westernmedication group(38 cases).The fire-acupuncture group was intervened by swift needling with fire needle,and simultaneously prescribed with Valaciclovir Hydrochloride tablets and Vitamin B1;the Western-medication group was by the same oral medicines alone.The therapeutic efficacies were evaluated afterwards.Results:The total effective rate was 95.1%in the fire-acupuncture group versus 89.5%in the Western-medication group,and the difference was statistically significant(P<0.05).After treatment,the concentration of substance P and visual analogue scale(VAS)score dropped significantly in both groups(both P<0.05);the inter-group differences were statistically significant(both P<0.05).Conclusion:Swift needling with fire needle plus medication has better therapeutic efficacy than medication alone in treating herpes zoster.展开更多
Objective To compare the difference of clinical efficacy of thin cotton moxibustion combined with plum-blossom needle and western medication in treatment of herpes zoster.Method Eighty patients with herpes zoster were...Objective To compare the difference of clinical efficacy of thin cotton moxibustion combined with plum-blossom needle and western medication in treatment of herpes zoster.Method Eighty patients with herpes zoster were divided into thin cotton moxibustion group（group A,n=40） and western medication group（group B,n=40） according to the sequence of admission.Patients in group A received thin cotton moxibustion that the colton was used as thin as a cicada＇s wings,combined with plum-blossom needle,and patients in group B received intravenous infusion with 0.25 g of acyclovir once a day,and acyclovir ointment application on affected part for 3-5 times per day.Five days were considered as a course of treatment.Analgesic effect and the incidence of postherpetic neuralgia were observed after two consecutive courses.Result The total effective rate was 97.5%（39/40） in group A,and80.0%（32/40） in group B（P〈0.05）;it was shown from the comparison of course between two groups that the cure rate after one in group A was markedly higher than that in group B（P〈0.01,P〈0.05）;the differences in effectual time and analgesic time between group A and group B were statistically significant（P〈0.05）;after treatment,the incidence of postherpetic neuralgia in group A was markedly lower than that in group B（P〈0.05）.Conclusion Thin cotton moxibustion combined with plum-blossom needle in treatment of herpes zoster can obviously shorten the time of therapy,effectively control pain,and reduce the incidence of postherpetic neuralgia.展开更多
Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan （龙眼, Extra） acupoint. M...Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan （龙眼, Extra） acupoint. Methods According to the random mumber table, 104 cases of herpes zoster were randomized into an observation group and a control group, 52 cases in each one. In the observation group, the blocking method was used at the starting site and the ending site of herpetic zone, the surrounding needling method was applied toward the center of the painful zone, with horizontal needling technique; and the local pricking and cupping methods as well as the bloodletting at Longyan （Extra） acupoint were adopted. In the control group, Jiáj （夹脊 EX-B 2） at the corresponding affected nerve segments and the local Ashi points were selected and stimulated with electroacupuncture. The visual analogue scale （VAS） was adopted to determine the analgesic effect 20 min, 1, 6, 12, 24 and 48 h after treatment separately in each group. Results The onset time of analgesic effect in the observation group was shorter than that in the control group and the efficacy time of duration was longer than that in the control group （all P0.05）. The analgesic effect and the result of comprehensive efficacy assessment were superior to those of the control group （both P0.05）. Conclusion The comprehensive therapy of blocking, surrounding needling, pricking and cupping method combined with bloodletting at Longyan （Extra） achieves the significant analgesic effect on herpes zoster.展开更多
Two cases of herpes zoster neuralgia treated by shallow needling combined with electroacupuncture were introduced. The literature basis and possible mechanisms were discussed.
Objective： To compare the clinical efficacies between thin-cotton moxibustion plus surround needling and Western medication in treating herpes zoster （HZ）. Methods： Eighty-three HZ patients were divided into two g...Objective： To compare the clinical efficacies between thin-cotton moxibustion plus surround needling and Western medication in treating herpes zoster （HZ）. Methods： Eighty-three HZ patients were divided into two groups according to their admission sequence, 41 cases in the thin-cotton moxibustion group and 42 cases in the Western medication group. The thin-cotton moxibustion group received thin-cotton moxibustion on the surface of lesions plus surround needling around the lesions, once a day. The Western medication group was intervened by Acyclovir intravenous injection, 0.25 g per dose, once a day, along with external application of Acyclovir cream 3-5 times a day. After 10-day treatment, the blister-healing time, crusting time, pain-reducing time, onset time of action, lesion-healed time, and occurrence of post-herpetic neuralgia （PHN） were compared. Results： During the study, a case dropped out in the thin-cotton moxibustion group, and 2 cases dropped out in the Western medication group. The recovery and markedly-effective rate was 92.5% and total effective rate was 97.5% in the thin-cotton moxibustion group, versus 72.5% and 87.5% in the Western medication group, and the between-group differences were statistically significant （P^0.05）. The blister-healing time, crusting time, pain-reducing time, onset time of action and lesion-healed time in the thin-cotton moxibustion group were significantly shorter than those in the Western medication group （P〈0.05）. The occurrence rate of PHN was 2.07% in the thin-cotton moxibustion group, significantly lower than 9.19% in the Western medication group （P〈0.01）. Conclusion： Thin-cotton moxibustion plus surround needling can produce a more significant efficacy than Acyclovir in treating HZ, and it can markedly reduce the occurrence of PHN.展开更多
文摘Introduction Herpes zoster is a skin disease caused by activation of the varicella zoster virus,which is latent in neurons.It can be accompanied by severe neuralgia.Some herpes zoster patients may have pain allergy,general discomfort,loss of appetite and other prodromal symptoms,typical clinical manifestation as a cluster of blisters distribution along unilateral peripheral nerve,often accompanied by obvious neuralgia[1].
文摘Objective:To evaluate the effectiveness and safety of fire needling for herpes zoster from randomized clinical trials (RCTs).Methods:We searched Cochrane Central Register of Controlled Trials,Pubmed,Sino-Med,CNKI,VIP,WanFang databases,and conference proceedings to November,2017.RCTs were eligible if they tested fire needling for treating herpes zoster more than 3 times.Two authors screened all references,assessed the risk of bias,extracted data,independently,and analyzed data using Trial Sequential Analysis (TSA).Treatment effects were presented as risk ratio (RR)for binary data and standardized mean difference (SMD) for continuous data with 95% confidence interval (CI).Results:We included 27 RCTs with a total of 1933 participants.Only one RCT had low risk of bias,and the others were of high or moderate risk of bias.For total effectiveness rate (proportion of total number of people who were cured or significant symptom improved),there was no significant difference between Western medicine (acyclovir,valacyclovir,adenosine cobalamin) and fire needling (risk ratio 1.05,95% CI 0.98 to 1.12;n =5).For pain relief (VAS scale):fire needling used alone showed lower scores than Western medicine (SMD-1.37,95% CI-1.77 to-0.97;n =2) or external medicine (diclofenac) (SMD-2.23,95% CI-2.81 to-1.64;n =1).Combination of fire needling and Western medicine was better than Western medicine alone in relieving pain (VAS scale) (SMD-2.19,95% CI-3.40 to-0.97,I2 =94%;n =4).Patients receiving fire needling had lower incidence of neuralgia than those receiving Western medicine (3.3% vs 26.7%,RR 0.09,95% Cl 0.01 to 0.82;n =1) at follow up for 30 days.No serious adverse events such as infection were reported.Conclusion:Fire needling appears to offer relief for alleviating pain in herpes zoster.As the sample size of included trials was small and the quality of studies was generally low,rigorous clinical trials with robust reporting and appropriate outcome measures are still needed.
文摘Objective:To compare the effectiveness of fire needle versus Western medicine in the treatment of herpes zoster.Methods:Randomized controlled trials comparing fire needle with Western medicine in the treatment of herpes zoster were identified using 8 databases.A meta-analysis was performed using RevMan 5.3 software.Results:Eight trials involving 569 patients were included in this meta-analysis,and the results showed that fire needle was superior to Western medicine comparing the effective rate[risk ratio(RR)=1.13,95%confidence interval(Cl):1.06 to 1.20;P=0.0002],the visual analog scale(VAS)score[mean difference(MD)=-7.95;95%Cl:-10.71 to-5.20;P<0.00001],time of pain disappearance(MD=-7.61;95%CI:-9.38 to-5.84;P<0.00001),time of blister-stop(MD=-1.34,95%CI:-1.51 to-1.18;P<0.00001),time of crusted scab(MD=-2.92,95%CI:-3.62 to-2.23;P<0.00001);and time of scab off(MD=-4.64,95%CI:-5.83 to-3.46;P<0.00001).In addition,a significantly lower incidence of postherpetic neuralgia was found in the fire needle group in 30 d(RR=0.23,95%CI:0.11 to 0.51;P=0.0002)and 60 d(RR=0.33,95%CI:0.12 to 0.91;P=0.03)after treatment.Conclusion:Fire needle has a favorable effect in increasing the effective rate,relieving pain,recovering skin lesions and decreasing incidence of postherpetic neuralgia in the treatment of herpes zoster.However,considering the limitations in this study,the findings should be interpreted cautiously.
文摘In recent 2 years, the author used a three-edged needle to scratch the vesicles for treatment of herpes zoster and obtained good therapeutic results as reported in the following. General Data 21 cases were observed in this series, including 12 males and 9 females, with ages ranging from 4 to 72 years. The shortest disease course was 1 day and the longest. 2 weeks. Clinical Manifestations There were 15 cases with groups
基金the support of Xinjiang Urumqi Hospital of Traditional Chinese Medicine
文摘Objective:To discuss the effectiveness and safety of swift needling with fire needle plus medication in treating herpes zoster and the change of substance P.Methods:Seventy-nine patients with herpes zoster were selected and randomized into a fire-acupuncture group(41 cases)and a Westernmedication group(38 cases).The fire-acupuncture group was intervened by swift needling with fire needle,and simultaneously prescribed with Valaciclovir Hydrochloride tablets and Vitamin B1;the Western-medication group was by the same oral medicines alone.The therapeutic efficacies were evaluated afterwards.Results:The total effective rate was 95.1%in the fire-acupuncture group versus 89.5%in the Western-medication group,and the difference was statistically significant(P<0.05).After treatment,the concentration of substance P and visual analogue scale(VAS)score dropped significantly in both groups(both P<0.05);the inter-group differences were statistically significant(both P<0.05).Conclusion:Swift needling with fire needle plus medication has better therapeutic efficacy than medication alone in treating herpes zoster.
文摘Objective To compare the difference of clinical efficacy of thin cotton moxibustion combined with plum-blossom needle and western medication in treatment of herpes zoster.Method Eighty patients with herpes zoster were divided into thin cotton moxibustion group（group A,n=40） and western medication group（group B,n=40） according to the sequence of admission.Patients in group A received thin cotton moxibustion that the colton was used as thin as a cicada＇s wings,combined with plum-blossom needle,and patients in group B received intravenous infusion with 0.25 g of acyclovir once a day,and acyclovir ointment application on affected part for 3-5 times per day.Five days were considered as a course of treatment.Analgesic effect and the incidence of postherpetic neuralgia were observed after two consecutive courses.Result The total effective rate was 97.5%（39/40） in group A,and80.0%（32/40） in group B（P〈0.05）;it was shown from the comparison of course between two groups that the cure rate after one in group A was markedly higher than that in group B（P〈0.01,P〈0.05）;the differences in effectual time and analgesic time between group A and group B were statistically significant（P〈0.05）;after treatment,the incidence of postherpetic neuralgia in group A was markedly lower than that in group B（P〈0.05）.Conclusion Thin cotton moxibustion combined with plum-blossom needle in treatment of herpes zoster can obviously shorten the time of therapy,effectively control pain,and reduce the incidence of postherpetic neuralgia.
文摘Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan （龙眼, Extra） acupoint. Methods According to the random mumber table, 104 cases of herpes zoster were randomized into an observation group and a control group, 52 cases in each one. In the observation group, the blocking method was used at the starting site and the ending site of herpetic zone, the surrounding needling method was applied toward the center of the painful zone, with horizontal needling technique; and the local pricking and cupping methods as well as the bloodletting at Longyan （Extra） acupoint were adopted. In the control group, Jiáj （夹脊 EX-B 2） at the corresponding affected nerve segments and the local Ashi points were selected and stimulated with electroacupuncture. The visual analogue scale （VAS） was adopted to determine the analgesic effect 20 min, 1, 6, 12, 24 and 48 h after treatment separately in each group. Results The onset time of analgesic effect in the observation group was shorter than that in the control group and the efficacy time of duration was longer than that in the control group （all P0.05）. The analgesic effect and the result of comprehensive efficacy assessment were superior to those of the control group （both P0.05）. Conclusion The comprehensive therapy of blocking, surrounding needling, pricking and cupping method combined with bloodletting at Longyan （Extra） achieves the significant analgesic effect on herpes zoster.
文摘Two cases of herpes zoster neuralgia treated by shallow needling combined with electroacupuncture were introduced. The literature basis and possible mechanisms were discussed.
文摘Objective： To compare the clinical efficacies between thin-cotton moxibustion plus surround needling and Western medication in treating herpes zoster （HZ）. Methods： Eighty-three HZ patients were divided into two groups according to their admission sequence, 41 cases in the thin-cotton moxibustion group and 42 cases in the Western medication group. The thin-cotton moxibustion group received thin-cotton moxibustion on the surface of lesions plus surround needling around the lesions, once a day. The Western medication group was intervened by Acyclovir intravenous injection, 0.25 g per dose, once a day, along with external application of Acyclovir cream 3-5 times a day. After 10-day treatment, the blister-healing time, crusting time, pain-reducing time, onset time of action, lesion-healed time, and occurrence of post-herpetic neuralgia （PHN） were compared. Results： During the study, a case dropped out in the thin-cotton moxibustion group, and 2 cases dropped out in the Western medication group. The recovery and markedly-effective rate was 92.5% and total effective rate was 97.5% in the thin-cotton moxibustion group, versus 72.5% and 87.5% in the Western medication group, and the between-group differences were statistically significant （P^0.05）. The blister-healing time, crusting time, pain-reducing time, onset time of action and lesion-healed time in the thin-cotton moxibustion group were significantly shorter than those in the Western medication group （P〈0.05）. The occurrence rate of PHN was 2.07% in the thin-cotton moxibustion group, significantly lower than 9.19% in the Western medication group （P〈0.01）. Conclusion： Thin-cotton moxibustion plus surround needling can produce a more significant efficacy than Acyclovir in treating HZ, and it can markedly reduce the occurrence of PHN.
