BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT ...BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT combined with mental health education as a treatment for schizophrenia compared with mental health education alone.METHODS In all,120 schizophrenia out-patients were randomized into CBGT combined with mental health education or single mental health education.The primary outcomes were positive and negative symptoms,cognitive function,excitatory factor,anxiety and depression symptom improvements on the positive and negative syndrome scale score.Secondary outcome measures included social function and drug compliance.RESULTS There were significant differences between CBGT combined with mental health education and single mental health education on measures of positive and negative symptoms,cognitive functions,excitatory factor,anxiety and depression symptoms,and social functions.No other significant difference in outcomes was observed.CONCLUSION CBGT combined with mental health education may be relevant beneficial treatment method in reducing symptoms,cognitive and social functions of patients with schizophrenia.展开更多
目的探讨综合心理干预对改善稳定期精神分裂症患者执行功能和社会功能的效果。方法纳入80例稳定期精神分裂症患者随机分为2组。试验组接受综合心理干预,对照组只接受医院提供的一般药物治疗以及常规心理相关知识宣教。在基线、干预结束...目的探讨综合心理干预对改善稳定期精神分裂症患者执行功能和社会功能的效果。方法纳入80例稳定期精神分裂症患者随机分为2组。试验组接受综合心理干预,对照组只接受医院提供的一般药物治疗以及常规心理相关知识宣教。在基线、干预结束后(第12周)评估症状严重程度、执行功能和社会功能。结果治疗12周后,试验组的阳性和阴性症状量表(Positive and Negative Syndrome Scale,PANSS)总分、阴性症状量表和一般精神病理量表分均低于对照组(P<0.05);威斯康星卡片分类测试(Wisconsin Card Sorting Test,WCST)持续性错误数和非持续性错误数低于对照组(P<0.05),连线测验(Trail Making Test,TMT)中A、B测验反应时间低于对照组(P<0.05),Stroop色词测验(Stroop Color Word Test,CWT)卡片A、B、C耗时、反映干扰量(stroop interference effect,SIE)耗时数和正确率低于对照组(P<0.05),卡片A、B、C正确率高于对照组(P<0.05);个体和社会功能量表(Personal and Social Performance Scale,PSP)评分高于对照组(P<0.05)。结论综合心理干预有助于减少稳定期精神分裂症患者的阴性症状,改善执行功能,提高社会功能。展开更多
目的:研究在线干预对精神分裂症患者依从性及社会功能的影响。方法:选取江西省精神病院三病区2021年10月—2022年4月收治的94例精神分裂症患者,采用随机数字表法分为对照组(n=47)与观察组(n=47)。对照组接受常规干预,观察组采用在线干预...目的:研究在线干预对精神分裂症患者依从性及社会功能的影响。方法:选取江西省精神病院三病区2021年10月—2022年4月收治的94例精神分裂症患者,采用随机数字表法分为对照组(n=47)与观察组(n=47)。对照组接受常规干预,观察组采用在线干预,对两组患者均进行为期9个月的干预。比较两组阳性和阴性精神症状评定量表(positive and negative syndrome scale,PANSS)评分、治疗依从性、个人与社会表现量表(personal and social performance scale,PSP)评分、疾病复发率和再住院率。结果:干预后两组阳性症状、阴性症状、一般精神病理评分及PANSS总分均显著低于干预前,且观察组阳性症状、阴性症状、一般精神病理评分及PANSS总分均显著低于对照组(P<0.05);干预后,观察组治疗依从性为93.62%,显著高于对照组的76.60%(P<0.05);干预后观察组社会有益活动、个人和社会关系、自我照料、扰乱及攻击行为评分均显著低于对照组,PSP总分显著高于对照组(P<0.05);干预后,观察组复发率为4.26%,显著低于对照组的19.15%(P<0.05),两组再住院率比较,差异无统计学意义(P>0.05)。结论:对精神分裂症患者采用在线干预可显著改善患者精神状况,提高患者治疗依从性,同时可改善患者社会功能,降低复发率和再住院率。展开更多
基金Supported by Science and Technology Innovation Bureau,Longhua District,Shenzhen,Guangdong Province,China,No.2020202.
文摘BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT combined with mental health education as a treatment for schizophrenia compared with mental health education alone.METHODS In all,120 schizophrenia out-patients were randomized into CBGT combined with mental health education or single mental health education.The primary outcomes were positive and negative symptoms,cognitive function,excitatory factor,anxiety and depression symptom improvements on the positive and negative syndrome scale score.Secondary outcome measures included social function and drug compliance.RESULTS There were significant differences between CBGT combined with mental health education and single mental health education on measures of positive and negative symptoms,cognitive functions,excitatory factor,anxiety and depression symptoms,and social functions.No other significant difference in outcomes was observed.CONCLUSION CBGT combined with mental health education may be relevant beneficial treatment method in reducing symptoms,cognitive and social functions of patients with schizophrenia.
文摘目的探讨综合心理干预对改善稳定期精神分裂症患者执行功能和社会功能的效果。方法纳入80例稳定期精神分裂症患者随机分为2组。试验组接受综合心理干预,对照组只接受医院提供的一般药物治疗以及常规心理相关知识宣教。在基线、干预结束后(第12周)评估症状严重程度、执行功能和社会功能。结果治疗12周后,试验组的阳性和阴性症状量表(Positive and Negative Syndrome Scale,PANSS)总分、阴性症状量表和一般精神病理量表分均低于对照组(P<0.05);威斯康星卡片分类测试(Wisconsin Card Sorting Test,WCST)持续性错误数和非持续性错误数低于对照组(P<0.05),连线测验(Trail Making Test,TMT)中A、B测验反应时间低于对照组(P<0.05),Stroop色词测验(Stroop Color Word Test,CWT)卡片A、B、C耗时、反映干扰量(stroop interference effect,SIE)耗时数和正确率低于对照组(P<0.05),卡片A、B、C正确率高于对照组(P<0.05);个体和社会功能量表(Personal and Social Performance Scale,PSP)评分高于对照组(P<0.05)。结论综合心理干预有助于减少稳定期精神分裂症患者的阴性症状,改善执行功能,提高社会功能。
文摘目的:研究在线干预对精神分裂症患者依从性及社会功能的影响。方法:选取江西省精神病院三病区2021年10月—2022年4月收治的94例精神分裂症患者,采用随机数字表法分为对照组(n=47)与观察组(n=47)。对照组接受常规干预,观察组采用在线干预,对两组患者均进行为期9个月的干预。比较两组阳性和阴性精神症状评定量表(positive and negative syndrome scale,PANSS)评分、治疗依从性、个人与社会表现量表(personal and social performance scale,PSP)评分、疾病复发率和再住院率。结果:干预后两组阳性症状、阴性症状、一般精神病理评分及PANSS总分均显著低于干预前,且观察组阳性症状、阴性症状、一般精神病理评分及PANSS总分均显著低于对照组(P<0.05);干预后,观察组治疗依从性为93.62%,显著高于对照组的76.60%(P<0.05);干预后观察组社会有益活动、个人和社会关系、自我照料、扰乱及攻击行为评分均显著低于对照组,PSP总分显著高于对照组(P<0.05);干预后,观察组复发率为4.26%,显著低于对照组的19.15%(P<0.05),两组再住院率比较,差异无统计学意义(P>0.05)。结论:对精神分裂症患者采用在线干预可显著改善患者精神状况,提高患者治疗依从性,同时可改善患者社会功能,降低复发率和再住院率。
