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Dynamic Event-Triggered Fixed-Time Consensus Control and Its Applications to Magnetic Map Construction
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作者 Jiayu Chai Qiang Lu +2 位作者 Xudong Tao Dongliang Peng Botao Zhang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第10期2000-2013,共14页
This article deals with the consensus problem of multi-agent systems by developing a fixed-time consensus control approach with a dynamic event-triggered rule. First, a new fixedtime stability condition is obtained wh... This article deals with the consensus problem of multi-agent systems by developing a fixed-time consensus control approach with a dynamic event-triggered rule. First, a new fixedtime stability condition is obtained where the less conservative settling time is given such that the theoretical settling time can well reflect the real consensus time. Second, a dynamic event-triggered rule is designed to decrease the use of chip and network resources where Zeno behaviors can be avoided after consensus is achieved, especially for finite/fixed-time consensus control approaches. Third, in terms of the developed dynamic event-triggered rule, a fixed-time consensus control approach by introducing a new item is proposed to coordinate the multi-agent system to reach consensus. The corresponding stability of the multi-agent system with the proposed control approach and dynamic eventtriggered rule is analyzed based on Lyapunov theory and the fixed-time stability theorem. At last, the effectiveness of the dynamic event-triggered fixed-time consensus control approach is verified by simulations and experiments for the problem of magnetic map construction based on multiple mobile robots. 展开更多
关键词 Dynamic event-triggered rule fixed-time consensus control fixed-time stability condition magnetic map construction multi-agent system
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Fixed-time Consensus for Leader-follower Second-order Multi-agent Systems 被引量:1
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作者 CHEN Mao-li WANG Xiao 《Chinese Quarterly Journal of Mathematics》 2019年第3期290-300,共11页
We analyse the fixed-time consensus problem for multi-agent systems with leaderfollower mode. Based on a follower’s observation structure for the leader’s information, it is proved that the estimation errors can be ... We analyse the fixed-time consensus problem for multi-agent systems with leaderfollower mode. Based on a follower’s observation structure for the leader’s information, it is proved that the estimation errors can be converged to zero at a fixed time. From this stability and a sliding mode structure, we derive a control input of followers, which provides a critical support for fixed-time consensus. The simulation results demonstrate that this control approach does conduce to the implementation of the fixed-time synchronization. 展开更多
关键词 LEADER-FOLLOWER SYNCHRONIZATION fixed-time STABILITY MULTI-AGENT SYSTEMS
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Event-Triggered Fixed-Time Consensus of Second-Order Nonlinear Multi-Agent Systems with Delay and Switching Topologies
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作者 XING Youjing GAO Jinfeng +1 位作者 LIU Xiaoping WU Ping 《Journal of Shanghai Jiaotong university(Science)》 EI 2024年第4期625-639,共15页
To address fixed-time consensus problems of a class of leader-follower second-order nonlinear multi-agent systems with uncertain external disturbances,the event-triggered fixed-time consensus protocol is proposed.Firs... To address fixed-time consensus problems of a class of leader-follower second-order nonlinear multi-agent systems with uncertain external disturbances,the event-triggered fixed-time consensus protocol is proposed.First,the virtual velocity is designed based on the backstepping control method to achieve the system consensus and the bound on convergence time only depending on the system parameters.Second,an event-triggered mechanism is presented to solve the problem of frequent communication between agents,and triggered condition based on state information is given for each follower.It is available to save communication resources,and the Zeno behaviors are excluded.Then,the delay and switching topologies of the system are also discussed.Next,the system stabilization is analyzed by Lyapunov stability theory.Finally,simulation results demonstrate the validity of the presented method. 展开更多
关键词 event-triggered mechanism fixed-time consensus multi-agent systems switching topologies
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Fixed-Time Antidisturbance Consensus Tracking for Nonlinear Multiagent Systems With Matching and Mismatching Disturbances
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作者 Xiangmin Tan Chunyan Hu +3 位作者 Guanzhen Cao Qinglai Wei Wei Li Bo Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第6期1410-1423,共14页
In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is prop... In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is proposed,which consists of a distributed fixed-time observer,a fixed-time disturbance observer,a nonsmooth antidisturbance backstepping controller,and the fixed-time stability analysis is conducted by using the Lyapunov theory correspondingly.This paper includes three main improvements.First,a distributed fixed-time observer is developed for each follower to obtain an estimate of the leader’s output by utilizing the topology of the communication network.Second,a fixed-time disturbance observer is given to estimate the lumped disturbances for feedforward compensation.Finally,a nonsmooth antidisturbance backstepping tracking controller with feedforward compensation for lumped disturbances is designed.In order to mitigate the“explosion of complexity”in the tradi-tional backstepping approach,we have implemented a modified nonsmooth command filter to enhance the performance of the closed-loop system.The simulation results show that the pro-posed method is effective. 展开更多
关键词 Antidisturbance BACKSTEPPING consensus tracking fixed-time stability multiagent system(MASs) strict feedback affine nonlinear systems.
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Fixed-time group consensus of second-order multi-agent systems based on event-triggered control
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作者 武肖帅 孙凤兰 +1 位作者 朱伟 Jürgen Kurths 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第7期329-336,共8页
The problem of fixed-time group consensus for second-order multi-agent systems with disturbances is investigated.For cooperative-competitive network,two different control protocols,fixed-time group consensus and fixed... The problem of fixed-time group consensus for second-order multi-agent systems with disturbances is investigated.For cooperative-competitive network,two different control protocols,fixed-time group consensus and fixed-time eventtriggered group consensus,are designed.It is demonstrated that there is no Zeno behavior under the designed eventtriggered control.Meanwhile,it is proved that for an arbitrary initial state of the system,group consensus within the settling time could be obtained under the proposed control protocols by using matrix analysis and graph theory.Finally,a series of numerical examples are propounded to illustrate the performance of the proposed control protocol. 展开更多
关键词 event-triggered control group consensus multi-agent system fixed-time
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Fixed-Time Gradient Flows for Solving Constrained Optimization: A Unified Approach
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作者 Xinli Shi Xiangping Xu +1 位作者 Guanghui Wen Jinde Cao 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第8期1849-1864,共16页
The accelerated method in solving optimization problems has always been an absorbing topic.Based on the fixedtime(FxT)stability of nonlinear dynamical systems,we provide a unified approach for designing FxT gradient f... The accelerated method in solving optimization problems has always been an absorbing topic.Based on the fixedtime(FxT)stability of nonlinear dynamical systems,we provide a unified approach for designing FxT gradient flows(FxTGFs).First,a general class of nonlinear functions in designing FxTGFs is provided.A unified method for designing first-order FxTGFs is shown under Polyak-Łjasiewicz inequality assumption,a weaker condition than strong convexity.When there exist both bounded and vanishing disturbances in the gradient flow,a specific class of nonsmooth robust FxTGFs with disturbance rejection is presented.Under the strict convexity assumption,Newton-based FxTGFs is given and further extended to solve time-varying optimization.Besides,the proposed FxTGFs are further used for solving equation-constrained optimization.Moreover,an FxT proximal gradient flow with a wide range of parameters is provided for solving nonsmooth composite optimization.To show the effectiveness of various FxTGFs,the static regret analyses for several typical FxTGFs are also provided in detail.Finally,the proposed FxTGFs are applied to solve two network problems,i.e.,the network consensus problem and solving a system linear equations,respectively,from the perspective of optimization.Particularly,by choosing component-wisely sign-preserving functions,these problems can be solved in a distributed way,which extends the existing results.The accelerated convergence and robustness of the proposed FxTGFs are validated in several numerical examples stemming from practical applications. 展开更多
关键词 consensus constrained optimization disturbance rejection linear equations fixed-time gradient flow(FxTGF).
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Hyperbolic Tangent Function-Based Protocols for Global/Semi-Global Finite-Time Consensus of Multi-Agent Systems
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作者 Zongyu Zuo Jingchuan Tang +1 位作者 Ruiqi Ke Qing-Long Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第6期1381-1397,共17页
This paper investigates the problem of global/semi-global finite-time consensus for integrator-type multi-agent sys-tems.New hyperbolic tangent function-based protocols are pro-posed to achieve global and semi-global ... This paper investigates the problem of global/semi-global finite-time consensus for integrator-type multi-agent sys-tems.New hyperbolic tangent function-based protocols are pro-posed to achieve global and semi-global finite-time consensus for both single-integrator and double-integrator multi-agent systems with leaderless undirected and leader-following directed commu-nication topologies.These new protocols not only provide an explicit upper-bound estimate for the settling time,but also have a user-prescribed bounded control level.In addition,compared to some existing results based on the saturation function,the pro-posed approach considerably simplifies the protocol design and the stability analysis.Illustrative examples and an application demonstrate the effectiveness of the proposed protocols. 展开更多
关键词 consensus protocol finite-time consensus hyper-bolic tangent function multi-agent systems.
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A Novel Disturbance Observer Based Fixed-Time Sliding Mode Control for Robotic Manipulators With Global Fast Convergence
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作者 Dan Zhang Jiabin Hu +2 位作者 Jun Cheng Zheng-Guang Wu Huaicheng Yan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期661-672,共12页
This paper proposes a new global fixed-time sliding mode control strategy for the trajectory tracking control of uncertain robotic manipulators.First,a fixed-time disturbance observer(FTDO) is designed to deal with th... This paper proposes a new global fixed-time sliding mode control strategy for the trajectory tracking control of uncertain robotic manipulators.First,a fixed-time disturbance observer(FTDO) is designed to deal with the adverse effects of model uncertainties and external disturbances in the manipulator systems.Then an adaptive scheme is used and the adaptive FTDO(AFTDO) is developed,so that the priori knowledge of the lumped disturbance is not required.Further,a new non-singular fast terminal sliding mode(NFTSM) surface is designed by using an arctan function,which helps to overcome the singularity problem and enhance the robustness of the system.Based on the estimation of the lumped disturbance by the AFTDO,a fixed-time non-singular fast terminal sliding mode controller(FTNFTSMC)is developed to guarantee the trajectory tracking errors converge to zero within a fixed time.The settling time is independent of the initial state of the system.In addition,the stability of the AFTDO and FTNFTSMC is strictly proved by using Lyapunov method.Finally,the fixed-time NFESM(FTNFTSM) algorithm is validated on a 2-link manipulator and comparisons with other existing sliding mode controllers(SMCs) are performed.The comparative results confirm that the FTNFTSMC has superior control performance. 展开更多
关键词 Disturbance observer(DO) fixed-time non-singular sliding mode control robotic manipulator trajectory tracking
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Bipartite consensus problems of Lurie multi-agent systems over signed graphs: A contraction approach
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作者 张晓娇 吴祥 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期137-145,共9页
This paper examines the bipartite consensus problems for the nonlinear multi-agent systems in Lurie dynamics form with cooperative and competitive communication between different agents. Based on the contraction theor... This paper examines the bipartite consensus problems for the nonlinear multi-agent systems in Lurie dynamics form with cooperative and competitive communication between different agents. Based on the contraction theory, some new conditions for the nonlinear Lurie multi-agent systems reaching bipartite leaderless consensus and bipartite tracking consensus are presented. Compared with the traditional methods, this approach degrades the dimensions of the conditions, eliminates some restrictions of the system matrix, and extends the range of the nonlinear function. Finally, two numerical examples are provided to illustrate the efficiency of our results. 展开更多
关键词 contraction theory virtual system bipartite consensus Lurie multi-agent systems
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CRBFT:A Byzantine Fault-Tolerant Consensus Protocol Based on Collaborative Filtering Recommendation for Blockchains
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作者 Xiangyu Wu Xuehui Du +3 位作者 Qiantao Yang Aodi Liu Na Wang Wenjuan Wang 《Computers, Materials & Continua》 SCIE EI 2024年第7期1491-1519,共29页
Blockchain has been widely used in finance,the Internet of Things(IoT),supply chains,and other scenarios as a revolutionary technology.Consensus protocol plays a vital role in blockchain,which helps all participants t... Blockchain has been widely used in finance,the Internet of Things(IoT),supply chains,and other scenarios as a revolutionary technology.Consensus protocol plays a vital role in blockchain,which helps all participants to maintain the storage state consistently.However,with the improvement of network environment complexity and system scale,blockchain development is limited by the performance,security,and scalability of the consensus protocol.To address this problem,this paper introduces the collaborative filtering mechanism commonly used in the recommendation system into the Practical Byzantine Fault Tolerance(PBFT)and proposes a Byzantine fault-tolerant(BFT)consensus protocol based on collaborative filtering recommendation(CRBFT).Specifically,an improved collaborative filtering recommendation method is designed to use the similarity between a node’s recommendation opinions and those of the recommender as a basis for determining whether to adopt the recommendation opinions.This can amplify the recommendation voice of good nodes,weaken the impact of cunningmalicious nodes on the trust value calculation,andmake the calculated resultsmore accurate.In addition,the nodes are given voting power according to their trust value,and a weight randomelection algorithm is designed and implemented to reduce the risk of attack.The experimental results show that CRBFT can effectively eliminate various malicious nodes and improve the performance of blockchain systems in complex network environments,and the feasibility of CRBFT is also proven by theoretical analysis. 展开更多
关键词 Blockchain consensus byzantine fault-tolerant collaborative filtering TRUST
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Evidence-based expert consensus on clinical management of safety of Bruton’s tyrosine kinase inhibitors(2024)
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作者 Zaiwei Song Dan Jiang +19 位作者 Lingling Yu Yixuan Chen Daobin Zhou Yue Li Depei Wu Lingli Zhang Liyan Miao Jun Ma Jun Zhu Hongmei Jing Rongsheng Zhao the Steering Committee,the Consensus Panel and the Evidence Synthesis Group Evidence-based Pharmacy Professional Committee of Chinese Pharmaceutical Association(CPA) Hospital Pharmacy Professional Committee of Chinese Pharmaceutical Association(CPA) Division of Therapeutic Drug Monitoring of Chinese Pharmacological Society(CPS) Expert Committee on Lymphoma of Chinese Society of Clinical Oncology(CSCO) Expert Committee on Leukemia of Chinese Society of Clinical Oncology(CSCO) Society of Integrative Cardio-Oncology of China Anti-Cancer Association(CACA) Chinese Society of Hematology of Chinese Medical Association(CMA) Hospital Pharmacy Professional Committee of Cross-Straits Medicine Exchange Association(SMEA) 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2024年第3期240-256,共17页
Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell lymphomas.However,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A... Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell lymphomas.However,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A comprehensive and systematic expert consensus from a pharmacological perspective is lacking for safety issues associated with BTKi treatment.A multidisciplinary consensus working group was established,comprising 35 members from the fields of hematology,cardiovascular disease,cardio-oncology,clinical pharmacy,and evidencebased medicine.This evidence-based expert consensus was formulated using an evidence-based approach and the Delphi method.The Joanna Briggs Institute Critical Appraisal(JBI)tool and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)approach were used to rate the quality of evidence and grade the strength of recommendations,respectively.This consensus provides practical recommendations for BTKis medication based on nine aspects within three domains,including the management of common adverse drug events such as bleeding,cardiovascular events,and hematological toxicity,as well as the management of drug-drug interactions and guidance for special populations.This multidisciplinary expert consensus could contribute to promoting a multi-dimensional,comprehensive and standardized management of BTKis. 展开更多
关键词 consensus BTK inhibitors SAFETY adverse drug events drug-drug interactions
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Designing Proportional-Integral Consensus Protocols for Second-Order Multi-Agent Systems Using Delayed and Memorized State Information
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作者 Honghai Wang Qing-Long Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期878-892,共15页
This paper is concerned with consensus of a secondorder linear time-invariant multi-agent system in the situation that there exists a communication delay among the agents in the network.A proportional-integral consens... This paper is concerned with consensus of a secondorder linear time-invariant multi-agent system in the situation that there exists a communication delay among the agents in the network.A proportional-integral consensus protocol is designed by using delayed and memorized state information.Under the proportional-integral consensus protocol,the consensus problem of the multi-agent system is transformed into the problem of asymptotic stability of the corresponding linear time-invariant time-delay system.Note that the location of the eigenvalues of the corresponding characteristic function of the linear time-invariant time-delay system not only determines the stability of the system,but also plays a critical role in the dynamic performance of the system.In this paper,based on recent results on the distribution of roots of quasi-polynomials,several necessary conditions for Hurwitz stability for a class of quasi-polynomials are first derived.Then allowable regions of consensus protocol parameters are estimated.Some necessary and sufficient conditions for determining effective protocol parameters are provided.The designed protocol can achieve consensus and improve the dynamic performance of the second-order multi-agent system.Moreover,the effects of delays on consensus of systems of harmonic oscillators/double integrators under proportional-integral consensus protocols are investigated.Furthermore,some results on proportional-integral consensus are derived for a class of high-order linear time-invariant multi-agent systems. 展开更多
关键词 consensus protocol Hurwitz stability multi-agent systems quasi-polynomials time delay
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A Bitcoin Address Multi-Classification Mechanism Based on Bipartite Graph-Based Maximization Consensus
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作者 Lejun Zhang Junjie Zhang +4 位作者 Kentaroh Toyoda Yuan Liu Jing Qiu Zhihong Tian Ran Guo 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期783-800,共18页
Bitcoin is widely used as the most classic electronic currency for various electronic services such as exchanges,gambling,marketplaces,and also scams such as high-yield investment projects.Identifying the services ope... Bitcoin is widely used as the most classic electronic currency for various electronic services such as exchanges,gambling,marketplaces,and also scams such as high-yield investment projects.Identifying the services operated by a Bitcoin address can help determine the risk level of that address and build an alert model accordingly.Feature engineering can also be used to flesh out labeled addresses and to analyze the current state of Bitcoin in a small way.In this paper,we address the problem of identifying multiple classes of Bitcoin services,and for the poor classification of individual addresses that do not have significant features,we propose a Bitcoin address identification scheme based on joint multi-model prediction using the mapping relationship between addresses and entities.The innovation of the method is to(1)Extract as many valuable features as possible when an address is given to facilitate the multi-class service identification task.(2)Unlike the general supervised model approach,this paper proposes a joint prediction scheme for multiple learners based on address-entity mapping relationships.Specifically,after obtaining the overall features,the address classification and entity clustering tasks are performed separately,and the results are subjected to graph-basedmaximization consensus.The final result ismade to baseline the individual address classification results while satisfying the constraint of having similarly behaving entities as far as possible.By testing and evaluating over 26,000 Bitcoin addresses,our feature extraction method captures more useful features.In addition,the combined multi-learner model obtained results that exceeded the baseline classifier reaching an accuracy of 77.4%. 展开更多
关键词 Bitcoin multi-service classification graph maximization consensus data security
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Fixed-Time Sliding Mode Control With Varying Exponent Coefficient for Modular Reconfigurable Flight Arrays
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作者 Jianquan Yang Chunxi Yang +1 位作者 Xiufeng Zhang Jing Na 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第2期514-528,共15页
The modular system can change its physical structure by self-assembly and self-disassembly between modules to dynamically adapt to task and environmental requirements. Recognizing the adaptive capability of modular sy... The modular system can change its physical structure by self-assembly and self-disassembly between modules to dynamically adapt to task and environmental requirements. Recognizing the adaptive capability of modular systems, we introduce a modular reconfigurable flight array(MRFA) to pursue a multifunction aircraft fitting for diverse tasks and requirements,and investigate the attitude control and the control allocation problem by using the modular reconfigurable flight array as a platform. First, considering the variable and irregular topological configuration of the modular array, a center-of-mass-independent flight array dynamics model is proposed to allow control allocation under over-actuated situations. Secondly, in order to meet the stable, fast and accurate attitude tracking performance of the MRFA, a fixed-time convergent sliding mode controller with state-dependent variable exponent coefficients is proposed to ensure fast convergence rate both away from and near the system equilibrium point without encountering the singularity. It is shown that the controller also has fixed-time convergent characteristics even in the presence of external disturbances. Finally,simulation results are provided to demonstrate the effectiveness of the proposed modeling and control strategies. 展开更多
关键词 Control allocation dynamic model fixed-time stabilization modular reconfigurable flight array(MRFA) sliding mode
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Fully Completed Spherical Fuzzy Approach-Based Z Numbers(PHIModel)for Enhanced Group Expert Consensus
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作者 Phi-Hung Nguyen 《Computers, Materials & Continua》 SCIE EI 2024年第7期1655-1675,共21页
This study aims to establish an expert consensus and enhance the efficacy of decision-making processes by integrating Spherical Fuzzy Sets(SFSs)and Z-Numbers(SFZs).A novel group expert consensus technique,the PHImodel... This study aims to establish an expert consensus and enhance the efficacy of decision-making processes by integrating Spherical Fuzzy Sets(SFSs)and Z-Numbers(SFZs).A novel group expert consensus technique,the PHImodel,is developed to address the inherent limitations of both SFSs and the traditional Delphi technique,particularly in uncertain,complex scenarios.In such contexts,the accuracy of expert knowledge and the confidence in their judgments are pivotal considerations.This study provides the fundamental operational principles and aggregation operators associated with SFSs and Z-numbers,encompassing weighted geometric and arithmetic operators alongside fully developed operators tailored for SFZs numbers.Subsequently,a case study and comparative analysis are conducted to illustrate the practicality and effectiveness of the proposed operators and methodologies.Integrating the PHI model with SFZs numbers represents a significant advancement in decision-making frameworks reliant on expert input.Further,this combination serves as a comprehensive tool for decision-makers,enabling them to achieve heightened levels of consensus while concurrently assessing the reliability of expert contributions.The case study results demonstrate the PHI model’s utility in resolving complex decision-making scenarios,showcasing its ability to improve consensus-building processes and enhance decision outcomes.Additionally,the comparative analysis highlights the superiority of the integrated approach over traditional methodologies,underscoring its potential to revolutionize decision-making practices in uncertain environments. 展开更多
关键词 Spherical fuzzy sets Delphi method Z-numbers expert consensus PHI model uncertainty
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Transperineal laser ablation of the prostate as a treatment for benign prostatic hyperplasia and prostate cancer: The results of a Delphi consensus project
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作者 Andrea Cocci Marta Pezzoli +35 位作者 Fernando Bianco Franco Blefari Pierluigi Bove Francois Cornud Gaetano De Rienzo Paolo Destefanis Danilo Di Trapani Alessandro Giacobbe Luca Giovanessi Antonino Laganà Giovanni Lughezzani Guglielmo Manenti Gianluca Muto Gianluigi Patelli Novello Pinzi Stefano Regusci Giorgio I.Russo Juan I.M.Salamanca Matteo Salvi Luigi Silvestri Fabrizio Verweij Eric Walser Riccardo GBertolo Valerio Iacovelli Alessandro Bertaccini Debora Marchiori Hugo Davila Pasquale Ditonno Paolo Gontero Gennaro Iapicca Theo M De Reijke Vito Ricapito Pierluca Pellegrini Andrea Minervini Sergio Serni Francesco Sessa 《Asian Journal of Urology》 CSCD 2024年第2期271-279,共9页
Objective: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) u... Objective: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) using the Delphi consensus method.Methods: Italian and international experts on BPH and PCa participated in a collaborative consensus project. During two rounds, they expressed their opinions on Echolaser® TPLA for the treatment of BPH and PCa answering online questionnaires on indications, methodology, and potential complications of this technology. Level of agreement or disagreement to reach consensus was set at 75%. If the consensus was not achieved, questions were modified after each round. A final round was performed during an online meeting, in which results were discussed and finalized.Results: Thirty-two out of forty invited experts participated and consensus was reached on all topics. Agreement was achieved on recommending Echolaser® TPLA as a treatment of BPH in patients with ample range of prostate volume, from <40 mL (80%) to >80 mL (80%), comorbidities (100%), antiplatelet or anticoagulant treatment (96%), indwelling catheter (77%), and strong will of preserving ejaculatory function (100%). Majority of respondents agreed that Echolaser® TPLA is a potential option for the treatment of localized PCa (78%) and recommended it for low-risk PCa (90%). During the final round, experts concluded that it can be used for intermediate-risk PCa and it should be proposed as an effective alternative to radical prostatectomy for patients with strong will of avoiding urinary incontinence and sexual dysfunction. Almost all participants agreed that the transperineal approach of this organ-sparing technique is safer than transrectal and transurethral approaches typical of other techniques (97% of agreement among experts). Pre-procedural assessment, technical aspects, post-procedural catheterization, pharmacological therapy, and expected outcomes were discussed, leading to statements and recommendations.Conclusion: Echolaser® TPLA is a safe and effective procedure that treats BPH and localized PCa with satisfactory functional and sexual outcomes. 展开更多
关键词 Transperineal laser ablation Prostatecancer Benignprostatic hyperplasia Delphi consensus
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Overlapping approach Proton Pump Inhibitors/Nux vomica-Heel as new intervention for gastro-esophageal reflux management:Delphi consensus study
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作者 Edda Battaglia Luciano Bertolusso +2 位作者 Marco Del Prete Marco Monzani Marco Astegiano 《World Journal of Gastroenterology》 SCIE CAS 2024年第18期2467-2478,共12页
BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitor... BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitors(PPIs)are considered the referring medications for GERD.Nevertheless,PPIs must be managed carefully because their use,especially chronic,could be linked with some adverse effects.An effective and safe alternative pharmacological tool for GERD is needed.After the identification of potentially new medications to flank PPIs,it is mandatory to revise and improve good clinical practices even through a consensus process.AIM To optimize diagnosis and treatment guidelines for GERD through a consensus based on Delphi method.METHODS The availability of clinical studies describing the action of the multicomponent/multitarget medication Nux vomica-Heel,subject of the consensus,is the basic prerequisite for the consensus itself.A modified Delphi process was used to reach a consensus among a panel of Italian GERD specialists on the overlapping approach PPIs/Nux vomica-Heel as a new intervention model for the management of GERD.The Voting Consensus group was composed of 49 Italian Medical Doctors with different specializations:Gastroenterology,otolaryngology,geriatrics,and general medicine.A scientific committee analyzed the literature,determined areas that required investigation(in agreement with the multiple-choice questionnaire results),and identified two topics of interest:(1)GERD disease;and(2)GERD treatment.Statements for each of these topics were then formulated and validated.The Delphi process involved two rounds of questioning submitted to the panel experts using an online platform.RESULTS According to their routinary GERD practice and current clinical evidence,the panel members provided feedback to each questionnaire statement.The experts evaluated 15 statements and reached consensus on all 15.The statements regarding the GERD disease showed high levels of agreement,with consensus ranging from 70%to 92%.The statements regarding the GERD treatment also showed very high levels of agreement,with consensus ranging from 90%to 100%.This Delphi process was able to reach consensus among physicians in relevant aspects of GERD management,such as the adoption of a new approach to treat patients with GERD based on the overlapping between PPIs and Nux vomica-Heel.The consensus was unanimous among the physicians with different specializations,underlying the uniqueness of the agreement reached to identify in the overlapping approach between PPIs and Nux vomica-Heel a new intervention model for GERD management.The results support that an effective approach to deprescribe PPIs through a progressive decalage timetable(reducing PPIs administration to as-needed use),should be considered.CONCLUSION Nux vomica-Heel appears to be a valid opportunity for GERD treatment to favor the deprescription of PPIs and to maintain low disease activity together with the symptomatology remission. 展开更多
关键词 Gastro-esophageal reflux disease Proton Pump Inhibitors consensus Nux vomica-Heel OVERLAPPING Decalage
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Mean nocturnal baseline impedance in gastro-esophageal reflux disease diagnosis:Should we strictly follow the Lyon 2 Consensus?
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作者 Theodoros A Voulgaris Georgios P Karamanolis 《World Journal of Gastroenterology》 SCIE CAS 2024年第26期3253-3256,共4页
Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux dis... Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux disease(GERD)is the one produced by the Lyon Consensus.Recently an updated second version has been released.Mean nocturnal baseline impedance(MNBI)was proposed by the first Consensus to act as supportive evidence for GERD diagnosis.Originally a cut-off of 2292 Ohms was proposed,a value revised in the second edition.The updated Consensus recommended that an MNBI<1500 Ohms strongly suggests GERD while a value>2500 Ohms can be used to refute GERD.The proposed cut-offs move in the correct direction by diminishing the original cut-off,nevertheless they arise from a study of normal subjects where cut-offs were provided by measuring the mean value±2SD and not in symptomatic patients.However,data exist that even symptomatic patients with inconclusive disease or reflux hypersensitivity(RH)show lower MNBI values in comparison to normal subjects or patients with functional heartburn(FH).Moreover,according to the data,MNBI,even among symptomatic patients,is affected by age and body mass index.Also,various studies have proposed different cut-offs by using receiver operating characteristic curve analysis even lower than the one proposed.Finally,no information is given for patients submitted to on-proton pump inhibitors pH-impedance studies even if new and extremely important data now exist.Therefore,even if MNBI is an extremely important tool when trying to approach patients with reflux symptoms and could distinguish conclusive GERD from RH or FH,its values should be interpreted with caution. 展开更多
关键词 Mean nocturnal baseline impedance Gastro-esophageal reflux disease Lyon 2 consensus pH-impedance DIAGNOSIS
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Opinion consensus incorporating higher-order interactions in individual-collective networks
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作者 叶顺 涂俐兰 +2 位作者 王先甲 胡佳 王薏潮 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期105-115,共11页
In the current information society, the dissemination mechanisms and evolution laws of individual or collective opinions and their behaviors are the research hot topics in the field of opinion dynamics. First, in this... In the current information society, the dissemination mechanisms and evolution laws of individual or collective opinions and their behaviors are the research hot topics in the field of opinion dynamics. First, in this paper, a two-layer network consisting of an individual-opinion layer and a collective-opinion layer is constructed, and a dissemination model of opinions incorporating higher-order interactions(i.e. OIHOI dissemination model) is proposed. Furthermore, the dynamic equations of opinion dissemination for both individuals and groups are presented. Using Lyapunov's first method,two equilibrium points, including the negative consensus point and positive consensus point, and the dynamic equations obtained for opinion dissemination, are analyzed theoretically. In addition, for individual opinions and collective opinions,some conditions for reaching negative consensus and positive consensus as well as the theoretical expression for the dissemination threshold are put forward. Numerical simulations are carried to verify the feasibility and effectiveness of the proposed theoretical results, as well as the influence of the intra-structure, inter-connections, and higher-order interactions on the dissemination and evolution of individual opinions. The main results are as follows.(i) When the intra-structure of the collective-opinion layer meets certain characteristics, then a negative or positive consensus is easier to reach for individuals.(ii) Both negative consensus and positive consensus perform best in mixed type of inter-connections in the two-layer network.(iii) Higher-order interactions can quickly eliminate differences in individual opinions, thereby enabling individuals to reach consensus faster. 展开更多
关键词 two-layer social networks individual and collective opinions higher-order interactions consensus Lyapunov's first method
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Dynamic Event-Triggered Consensus Control for Input Constrained Multi-Agent Systems With a Designable Minimum Inter-Event Time
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作者 Meilin Li Yue Long +2 位作者 Tieshan Li Hongjing Liang C.L.Philip Chen 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期649-660,共12页
This paper investigates the consensus control of multi-agent systems(MASs) with constrained input using the dynamic event-triggered mechanism(ETM).Consider the MASs with small-scale networks where a centralized dynami... This paper investigates the consensus control of multi-agent systems(MASs) with constrained input using the dynamic event-triggered mechanism(ETM).Consider the MASs with small-scale networks where a centralized dynamic ETM with global information of the MASs is first designed.Then,a distributed dynamic ETM which only uses local information is developed for the MASs with large-scale networks.It is shown that the semi-global consensus of the MASs can be achieved by the designed bounded control protocol where the Zeno phenomenon is eliminated by a designable minimum inter-event time.In addition,it is easier to find a trade-off between the convergence rate and the minimum inter-event time by an adjustable parameter.Furthermore,the results are extended to regional consensus of the MASs with the bounded control protocol.Numerical simulations show the effectiveness of the proposed approach. 展开更多
关键词 Constrained input designable minimum inter-event time directed communication topology dynamic event-triggered mechanism MASs consensus control
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