When the Combination of a Chinese Flap and Dufourmentel Makes It Possible to Treat a Hopeless Case of Squamous Cell Carcinoma of the Upper Lip

Cancers of the lip are the leading cause of labial defects, and treatment is essentially surgical. The success of a repair is assessed by two essential criteria: The functional character of the lip (restoration of continence allowing feeding) and the aesthetic quality of the repair. However, for many patients from countries whose medical infrastructure does not allow them to undertake complex reconstructions locally, medical transfers represent their only chance of treatment. The aim of this article is to share with you an extreme clinical case of labial reconstruction, the management of which was a real challenge, using two major flaps: the free ante-brachial flap and the DUFOURMENTEL-type bi-pediculated scalp flap.

Clinical observation of removal of the necrotic corneal tissue combined with conjunctival flap covering surgery under the guidance of the AS-OCT in treatment of fungal keratitis

AIM: To study the clinical observation of removal of the necrotic corneal tissue combined with conjunctival flap covering surgery under the guidance of the AS-OCT in treatment of fungal keratitis. METHODS:A retrospective study was done to 10 patients (10 eyes) who had accepted removal of the necrotic corneal tissue combined with conjunctival flap covering surgery for fungal keratitis,the diagnosis by corneal scraping and smear examination or confocal microscopy check hyphae. Local and systemic antifungal therapy more than one week for all patients, corneal ulcer enlarge or no shrink. Slit lamp microscope examination the diameter of corneal ulcer about 2mm-4mm. Anterior segment optical coherence tomography (AS-OCT)examine the depth of corneal ulcer between 1/3-1/2, infiltrate corneal stroma about 20um-80um,the diameter of corneal ulcer about 3mm-6mm.Type-B ultrasonic exclusion endophthalmitis. Complete removal lesions until transparent of stoma, make conjunctival flap equal or greater than ulcer 1mm nearby conjunctiva. Continued antifungal therapy. The vision, fungal recurrence, conjunctival flap rollback or desquamate were analysed. ' RESULTS:Ten patients had success done this surgery, the corneal ulcer was not enlarge and healing afteroperation. 7 cases were bridging conjunctival flap and 3cases were single conjunctival flap. Preoperation vision above 0.1 had 8 cases,7 cases had vision above 0.1 one week after surgery, while 1 cases vision droped from 0.3 to 0.05.There was not recurrent for fungal,2 cases conjunctival flap rollback:1 case was bridging and 1case was single flap, no conjunctival flap desquamate. CONCLUSION: It is safe and effective to perform removal of the necrotic corneal tissue combined with conjunctival flap covering surgery under the guidance of the AS-OCT in treatment of fungal keratitis which werenot sensitive or aggravate for antifungal drugs.

Erector Spinae Plane Block for Mastectomy and Breast Flap Reconstructive Surgery: A Three Case Series

Uncontrolled pain after breast surgery can have early to chronic repercussions. The repertoire of pre-emptive opioid-sparing analgesic options includes regional blocks such as paravertebral blocks to myofascial blocks and more recently the Erector Spinae (ESP) block. Case 1 demonstrates the ESP block as an easy and conveniently performed post-operative rescue block for a patient who still experienced uncontrolled pain despite a combination of myofascial blocks and systemic analgesics. Case 2 and 3 demonstrate the advantage of providing an extensive coverage of surgical field in breast reconstruction surgery covering variable donor sites. It was due to the extent of coverage, that allowed the placement of ESP block catheter distantly without interrupting the surgical site. Post operative prolongation of pain relief was also successful by titrating analgesia via intermittent boluses. In our case series, the ESP block consistently and safely provided satisfactory pain relief for breast reconstruction surgery. It can be a viable option for peri-operative analgesia compared to other more invasive or less extensive alternatives.

Histological Findings of a Local Adipofascial Flap That Was Implanted during Breast Conserving Surgery

We report a patient with breast cancer whose breast was immediately reconstructed using a local adipofascial flap and was then subsequently resected 3 years after the original surgical procedure due to local recurrence. In order to achieve local control of the solitary recurrent lesion, we resected the remnant breast, which gave us a useful opportunity to examine the previously implanted flap histologically. A 33-year-old Japanese female was diagnosed with T2N0M0 breast cancer in the outer area of her left breast and underwent partial mastectomy with immediate reconstruction using a local adipofascial flap. The breast lesion was considered to be invasive ductal carcinoma, scirrhous carcinoma, lymphatic invasion+, venous invasion-, estrogen receptor+, progesterone receptor+, and HER2/neu-. Involvement was noted in three of the twenty-five resected axillary lymph nodes. She received adjuvant hormone therapy, but developed a solitary local recurrence of the skin forty-five months after the initial procedure, for which she received total mastectomy, systemic chemotherapy, and hormone therapy. During the histological examination of the local adipofascial flap that had been implanted into the partial breast defect, normal fatty tissue and the implanted fascia were seen at the implantation site. This is a rare report in which a local flap that was implanted during oncoplastic breast surgery was histologically examined.

A Case Report of Immediate Implant Placement Combined with Flap Surgery,Guided Bone Regeneration and Non-submerged Healing with a Labial Bone Wall Defect in the Esthetic Zone

[Basckground]This case report presented a methodology for immediate implantation in the esthetic zone with a facial bone defect along with flap surgery,guided bone regeneration,and non-submerged healing.[Case presentation]A 27-year-old female patient was complaining of the aesthetic complication that was caused via metallic staining of the neck of ceramic crowns in the maxillary right anterior region for one year.She has experienced immediate implantation along with flap surgery,guided bone regeneration(GBR),and non-submerged healing.The torque of the implant reached to the 35 N·cm to confirm primary stability.Six months after surgery,the healing abutment and the implant were fixed,the gingiva was healthy in the surgical area,and the nearby teeth and the opposite teeth were normal.[Results]The results of cone-beam computer tomography(CBCT)revealed that bone defects were filled with the newly formed bone.At the same time,the final impressions accomplished,and an all-ceramic crown was fit-placed.As a whole,the patient satisfaction rate was high.[Conclusions]Immediate implant placement with flap surgery,GBR,and non-submerged healing with a facial bone wall defect in the esthetic zone is an achievable process.

Surgical Outcomes Following Partial Breast Reconstruction with Chest Wall Perforator Flaps

Introduction: In the last two decades, chest wall perforator flaps (CWPF) have become a versatile tissue replacement technique for partial breast reconstruction following breast-conserving surgery (BCS) in well-selected cases. We present the surgical outcome of 81 patients with chest wall perforator flaps used for breast-conserving surgery. Methods: We recorded the outcomes of three oncoplastic breast surgeons who performed partial breast reconstruction with chest wall perforator flaps from 1st January 2018 to 30th June 2022 at Sherwood Forest Hospitals NHS Foundation Trust. Data were collected on patient demographics, including age, BMI, smoking status, bra size, previous treatments, type of CWPF procedure, tumor size (measured clinically, via imaging and histologically), biopsy results, specimen weight, margins involvement, re-operation rate, surgical site infection (SSI), flap loss, flap shrinkage, hematoma, and seroma rates. Results: A total of 81 patients were included in this study, with an average age of 55.7 years and a body mass index (BMI) of 26.7 kg/m2. The bra size varied between A to FF with A (7.4%), B (28.3%), C (38.2%), D (13.6%), DD (11.1%), and FF (1.2%). 14.8% of the patients had neoadjuvant chemotherapy (NACT). For 45 patients, LICAP (lateral intercostal artery perforator), 16 AICAP (anterior intercostal artery perforator), 13 MICAP (medial intercostal artery perforator), and for seven patients, LTAP (lateral thoracic artery perforator) flaps were used. The average tumor was measured at 15.75 mm clinically, 19.1 mm via imaging, and 19.6 mm histologically. Biopsy showed that 16% of the tumors were ductal carcinoma in situ (DCIS), and 84% were invasive. 16% of patients had involved margins, and re-excision was required in 10 patients, and completion mastectomy was performed in 2 patients. A thirty-day SSI rate was 6.2%, with flap-related complications, including flap loss and shrinkage, at 3.7% and 4.9%, respectively. In addition, 3.7% had a hematoma, and 17.3% had other complications. Conclusion: Partial breast reconstruction with perforator flaps is an excellent volume replacement technique in breast-conserving surgery with acceptable complications in well-selected cases.

System describing surgical field extension associated with flap reconstruction after resection of a superficial malignant soft tissue tumor

BACKGROUND Flap reconstruction after resection of a superficial malignant soft tissue tumor extends the surgical field and is an indicator for potential recurrence sites.AIM To describe a grading system for surgical field extension of soft tissue sarcomas.METHODS Grading system:CD-grading is a description system consisting of C and D values in the surgical field extension,which are related to the compartmental position of the flap beyond the nearby large joint and deeper extension for the pedicle,respectively.C1/D1 are positive values and C0/D0 are negative.With a known location,1/0 values can be"p"(proximal),"d"(distal),and"b"(in the tumor bed),and the description method is as follows:flap type,CxDx[x=0,1,p,d or b].RESULTS Four representative patients with subcutaneous sarcomas who underwent reconstruction using fasciocutaneous flaps are presented.The cases involved a distal upper arm(elbow)synovial sarcoma reconstructed using a pedicled latissimus dorsi(pedicled flap:CpDp);a distal upper arm(elbow)pleomorphic rhabdomyosarcoma reconstructed using a transpositional flap from the forearm(transpositional flap:CdD0);an undifferentiated pleomorphic sarcoma in the buttocks reconstructed using a transpositional flap(transpositional flap:C0D0);and a myxofibrosarcoma in the buttocks reconstructed using a propeller flap from the thigh(pedicled flap:CdDd).CONCLUSION The reconstruction method is chosen by the surgeon based on size,location,and other tumor characteristics;however,the final surgical field cannot be determined based on preoperative images alone.CD-grading is a description system consisting of C and D values in the surgical field extension that are related to the compartmental position of the flap beyond the nearby large joint and deeper extension for the pedicle,respectively.The CD-grading system gives a new perspective to the flap reconstruction classification.The CD-grading system also provides important information for follow-up imaging of a possible recurrence.

改良膜龈手术在牙龈退缩治疗中的应用

随着人们对美观需求的日益提升,治疗牙龈退缩已经成为牙周科临床常见的患者诉求。临床上主要通过手术的方式治疗牙龈退缩,常见的手术包括游离龈移植术、带蒂瓣技术和双层瓣技术,适应证选择恰当时,通常可以获得满意的效果,但上述术式仍存在一定的不足,如根面覆盖效果不理想等。近年来,学者们针对这些不足陆续提出了一些改良方案来治疗不同程度的牙龈退缩,如改良游离龈移植术,即包含龈乳头及游离龈的牙龈单元移植,可改善受体区血供,提高根面覆盖效果,其针对轻度退缩的部位可获得良好的根面覆盖,同时可增宽角化龈和加深前庭沟,但应用于上颌美学区时可能存在术后牙龈颜色、形态不协调,美学效果欠佳的问题。牙龈瓣采用半厚-全厚-半厚的技术进行制备的改良冠向复位瓣,用于多颗牙牙龈退缩时,以退缩最严重牙为中心的改良切口设计的冠向复位信封瓣技术,可提高根面覆盖效果。不离断龈乳头,使龈瓣形成隧道,以容纳移植物的隧道技术及各种改良的隧道技术,可以有效减少术区的组织损伤,并促进创面愈合。本文通过对各类术式的阐述和文献回顾,总结改良膜龈手术治疗牙龈退缩的临床应用及注意事项,并提出牙龈退缩的治疗方案建议,同时强调牙龈退缩的对因治疗,以达到稳定的根面覆盖效果。创伤小、疗效稳定的手术方式和治疗方法是今后膜龈手术的发展方向。

52例猫坏死性角膜炎病例报告

猫坏死性角膜炎是一种常见的猫角膜疾病,我国针对该病的研究较少,治疗方案不一。本试验收集2019年1月─2021年1月在中国农业大学动物医院就诊的52例猫坏死性角膜炎病例(共56只患眼),对病例统计分析,总结该病特征性的临床症状,讨论不同治疗方案的优缺点。结果显示,猫坏死性角膜炎高发品种为异国短毛猫(22/52,42.3%),高发年龄段为<7岁(50/52,96.2%),慢性角膜刺激是该病的常见病因。在52例患猫病例中,34例(共38只患眼)进行角膜切除术治疗,其中22只患眼同时进行了第三眼睑遮盖术,另外16只患眼同时进行了结膜瓣遮盖术。2例患猫病例术后出现坏死性角膜炎复发,均为年轻斯芬克斯猫。结果表明,角膜切除术是治疗猫坏死性角膜炎的首选治疗方案,坏死角膜的残留可能造成术后复发。

鼻内镜下经翼突入路手术中同侧鼻中隔黏膜瓣血运的保护及应用

目的 探讨鼻内镜下经翼突入路颅底手术中制备同侧鼻中隔黏膜瓣的技术要点及其有效性。方法 回顾性分析我科2021年3月~2022年2月鼻内镜下经翼突入路切除病变的7例放疗后鼻咽坏死和5例蝶窦侧隐窝脑膜脑膨出患者。术中,将同侧鼻中隔黏膜瓣根蒂分离到蝶腭孔周围后,再将黏膜瓣蒂部向外侧翻转以暴露翼突并保留供血动脉。总结术中同侧鼻中隔黏膜瓣的制备要点及其有效性。结果 本组12例患者同侧鼻中隔黏膜瓣全部成活,创面上皮化良好。术后,放疗后鼻咽坏死患者头痛和鼻腔恶臭症状均明显缓解,均未发生面部或软腭、硬颚麻木感;蝶窦侧隐窝脑膜脑膨出患者脑脊液鼻漏均治愈,但在术后,有2例出现面部麻木,3例软腭及硬颚麻木。结论 鼻内镜下经翼突入路手术中保留同侧鼻中隔黏膜瓣及其血运,能有效修补鼻咽部和蝶窦侧隐窝创面及颅底缺损。

基于预见性策略的精准护理用于口腔颌面肿瘤皮瓣修复术后的临床观察

目的 探讨基于预见性策略的精准护理用于口腔颌面肿瘤皮瓣修复术后的临床效果。方法 本研究选取2021年6月至2023年6月于新乡市中心医院收治的口腔颌面肿瘤皮瓣修复术后患者81例,所有患者均接受基于预见性策略的精准护理,对患者护理前后康复情况进行比较分析。结果 患者术后3 d的疼痛、皮瓣颜色、温度及毛细血管充盈度评分较术后6 h显著降低,差异有统计学意义(P<0.05)。本组患者中发生轻微感染2例,皮肤感觉异常1例,血管危象1例患者,并发症发生率为4.94%(4/81)。护理后患者生活质量评分较护理前高,差异有统计学意义(P<0.05),护理满意度为96.30%。结论口腔颌面肿瘤皮瓣修复术后应用基于预见性策略的精准护理可改善皮瓣状态,减少并发症,患者生活质量及护理满意度高。

乳腺癌改良根治术后皮瓣坏死的危险因素分析

目的分析探讨乳腺癌改良根治术后皮瓣坏死的危险因素。方法选取2021年1月至2022年2月河南科技大学第一附属医院收治的92例拟行乳腺癌改良根治术治疗的乳腺癌患者作为研究对象,收集患者年龄、乳腺癌分期、病灶部位、肿瘤长径、病理分型、皮瓣厚度、皮瓣张力、包扎压力、是否合并糖尿病、术后是否发生皮瓣坏死等临床资料,并依据术后皮瓣坏死发生情况将其分为正常组与坏死组,多因素Logistic回归分析乳腺癌改良根治术后皮瓣坏死的危险因素。结果92例乳腺癌患者中乳腺癌改良根治术后出现皮瓣坏死30例(3261%),设为坏死组;未出现皮瓣坏死62例(6739%),设为正常组。单因素分析结果显示,坏死组皮瓣薄、皮瓣张力高、包扎过紧、合并糖尿病的患者比例均明显高于正常组(χ^(2)=6550、6753、6418、6332,P=0010、0009、0011、0012);多因素Logistic回归分析结果显示,皮瓣薄、皮瓣张力高、包扎过紧以及合并糖尿病是乳腺癌改良根治术后皮瓣坏死的独立危险因素(95%CI为1313~4533、1059~2640、1124~4277、1180~3899,P=0005、0028、0022、0013)。结论皮瓣薄、皮瓣张力高、包扎过紧以及合并糖尿病是乳腺癌改良根治术后皮瓣坏死的独立危险因素。

去骨瓣减压术治疗颅脑损伤后血肿增大的风险因素分析

目的研究去骨瓣减压术治疗颅脑损伤后血肿增大的风险因素。方法回顾性分析2022年1月至2023年8月本院收治的颅脑损伤117例,所有患者均行去骨瓣减压术,根据术后CT检查血肿是否增大分为发生组(n=62)与未发生组(n=55)。比较两组一般资料及鹿特丹CT评分(Rotterdam CT)、格拉斯哥昏迷评分(GCS)间的差异,经多因素Logistic回归分析去骨瓣减压术治疗颅脑损伤后血肿增大的危险因素。结果两组患者性别、合并高血压、高脂血症、冠心病比较差异无统计学意义(P>0.05),发生组年龄≥65岁、瞳孔散大、发病至开颅时间<4h占比及RotterdamCT评分、血糖、骨瓣最大径明显高于非血肿增大组,GCS评分低于未发生组,差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,年龄、Rotterdam CT评分、GCS评分、瞳孔状态、发病至开颅时间、血糖、骨瓣最大径是颅脑损伤患者术后血肿增大的危险因素(P<0.05)。结论颅脑损伤患者术后血肿增大受诸多因素影响,其中年龄、瞳孔状态、GCS评分、Rotterdam CT评分、发病至开颅时间、血糖、骨瓣最大径可预测患者术后血肿情况,应予以密切关注。

基于加速康复外科理念的集束化护理模式对游离穿支皮瓣修复上肢创面患者疾病预后的影响

目的研究基于加速康复外科理念的集束化护理模式对游离穿支皮瓣修复上肢创面患者疾病预后的影响。方法回顾性分析2020年3月~2022年11月于南阳市中心医院骨科接受游离穿支皮瓣修复上肢创面患者48例。根据入院时间不同分为对照组和试验组,对照组(24例)入院时间为2020年3月~2021年6月采用常规护理,试验组(24例)入院时间为2021年7月~2022年11月采用加速康复外科理念的集束化护理。分析两组患者术后创面愈合时间、住院时间、疼痛程度、修复效果、术后并发症、患者满意度。结果试验组患者创面愈合时间和住院时间、术后6h、24h、36h、72hNRS得分、术后1月VSS总分及各项评分以及术后并发症发生率均低于对照组,试验组患者满意度高于对照组,差异有统计学意义(P﹤0.05)。结论在游离穿支皮瓣修复上肢创面患者应用基于加速康复外科理念的集束化护理模式可以缩短患者术后创面愈合时间和住院时间、缓解疼痛程度、提高修复效果和患者满意度、降低术后并发症。

愈灵液对乳腺癌术后皮瓣恢复影响的临床疗效观察

目的:观察愈灵液对乳腺癌术后皮瓣恢复的临床效果。方法:将2018年1月—2022年1月,安徽中医药大学附属滁州中西医结合医院普外科行乳腺癌改良根治术40例患者,随机分为对照组和观察组,每组20例。两组患者均予以相同的改良根治手术以及术后相同的护理方式,对照组采用常规碘伏消毒,观察组在对照组基础上加用愈灵液外敷换药,每三天换药一次,观察15天内住院期间患者皮瓣愈合情况。结果:观察组20例患者皮瓣均无坏死,总有效率100%,对照组无坏死15例,轻度坏死4例,中度坏死1例,总有效率75%,两组比较差异具有统计学意义(P=0.047)。结论:愈灵液能有效减少皮瓣坏死的发生,促进皮瓣恢复,值得临床推广。

手外科血管危象预防护理质量评价指标的构建及应用

目的构建手外科血管危象预防护理质量评价指标,并评价应用效果。方法以三维质量结构模式为理论框架,通过文献分析、半结构访谈及专家函询构建手外科血管危象预防护理质量评价指标。将200例单指断指再植或皮瓣移植患者按照入院时间分为对照组和观察组各100例,对照组给予常规护理,观察组根据构建的手外科血管危象预防护理质量评价指标进行护理。结果构建的手外科血管危象预防护理质量评价指标体系包含结构质量、过程质量、结果质量3项一级指标,10项二级指标及47项三级指标。质量评价指标应用后,观察组血管危象及时发现率、断指再植或移植皮瓣成活率及患者满意度评分显著高于对照组,患者血管危象发生率显著低于对照组(均P<0.05)。结论构建并应用手外科血管危象预防护理质量指标有利于及时发现血管危象,降低血管危象发生率,提高再植手指或移植皮瓣成活率及患者满意度。

颅骨缺损颅骨修补术后应用中药“独一味”对皮瓣下积液的疗效

目的探讨颅骨缺损颅骨修补术后应用中药独一味对皮瓣下积液疗效的研究。方法该研究所有病例均来自于2019年1月—2023年9月期间医院脑外科收治符合纳入标准的颅骨修补术后合并皮瓣下积液患者共92例,根据随机数字法将所有患者分为试验组(46例)与对照组(46例)。所有颅骨修补手术均在相同手术消毒标准的手术室内进行,对照组根据皮瓣下积液情况予以对症处理,试验组在对照组的基础上予以中药独一味。对比两组临床治疗效果、血清肿瘤坏死因子-α(Serum tumor necrosis factor-α,TNF-α)、白细胞介素-8(Interleukin-8,IL-8)、降钙素原(procalcitonin,PCT)水平、生活质量、并发症反应情况。应用SPSS24.0统计进行统计分析。结果与对照组相比,试验组临床有效率较高(P<0.05)。与治疗前相比,治疗后血清TNF-α、IL-8及PCT水平降低(P<0.05);疗后与对照组相比,试验组血清TNF-α、IL-8及PCT水平较低(P<0.05)。与治疗前相比,治疗后功能领域、总体健康状况等生活质量评分升高,症状领域评分降低(P<0.05);疗后与对照组相比,试验组功能领域、总体健康状况方面生活质量评分较高,症状领域评分较低(P<0.05)。与对照组相比,试验组并发症发生率较低(P<0.05)。结论将中药独一味应用于颅骨缺损颅骨修补术后合并皮瓣下积液的治疗中,能够显著提高疗效及生活质量,副作用少,其治疗机制可能与抑制TNF-α、IL-8及PCT水平有相关性。

香蕉-下颌模型在牙周翻瓣术实验教学中的效果评价

目的评价香蕉-下颌模型用于牙周翻瓣术实验教学中的效果。方法于2022年4月—5月招募西北民族大学66名四年级本科生,采用随机数表法将其分为单纯使用香蕉模型(B)、单纯使用传统下颌模型(T)和使用香蕉-下颌联合模型(B-T)3组,每组22名。B组使用香蕉模型作为牙周翻瓣术训练模型;T组使用传统下颌模型作为牙周翻瓣术训练模型;B-T组先使用香蕉模型训练,后使用下颌模型训练。训练时间为2 h。3组均进行牙周翻瓣术临床前模拟训练。每组按顺序进行理论知识教学、第一次理论测试、牙周翻瓣术操作练习、第二次理论测试、操作考核和满意度调查。比较3组实验训练前后的理论测试评分、操作考核评分和满意度。结果3组实验组训练前理论测试成绩比较,差异无统计学意义(P>0.05);B-T组的训练后理论测试成绩[(77.27±15.73)分]高于训练前理论测试[(58.52±17.84)分],差异有统计学意义(P<0.05);B组训练后理论测试成绩[(63.64±16.77)分]亦高于训练前测试考试[(53.41±13.46)分],差异有统计学意义(P<0.05),而T组2次训练前后理论成绩比较[(50.57±20.59)分vs.(53.41±10.34)分],差异无统计学意义(P>0.05)。操作考核从高到低排名依次是B-T组、T组和B组[(79.66±3.56)分、(76.20±6.31)分、(73.18±3.81)分],差异有统计学意义(P<0.05)。满意度调查显示B-T组更利于理论知识的巩固和临床技能的提高,差异有统计学意义(P<0.05),B组及T组在课堂丰富度、引入必要性、增加操作信心、巩固理论知识、提高临床技能和操作主观感受比较,差异均无统计学意义(P>0.05)。结论运用香蕉-下颌模型进行牙周翻瓣术教学,能够提高口腔医学生理论知识和操作技能,为牙周翻瓣术实验教学提供一种可选策略。

微创术治疗自发性脑出血灶周水肿的效果

目的探讨微创术治疗自发性脑出血灶周水肿的疗效及对脑水肿指数、脑脊液水平的影响,以期为临床优化治疗方案提供理论依据。方法采用前瞻性随机对照研究,选取2020年6月至2022年6月收治的78例自发性脑出血合并出血灶周水肿患者作为研究对象,采用随机数字表、密封信法分为观察组(39例)与对照组(39例),对照组接受开颅大骨瓣减压术治疗,观察组接受立体定向手术抽吸治疗。观察两组患者术后3个月的手术疗效,记录两组围手术期指标(手术、住院时间),比较两组术前、术后14 d的脑水肿指数、脑脊液水平[白细胞介素-1β(IL-1β)、S-100钙结合蛋白β(S-100β)]以及术后并发症发生情况。结果术后3个月,观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。观察组手术、住院时间短于对照组,差异有统计学意义(P<0.05)。术后5 d,两组患者脑水肿指数均下降,且观察组小于对照组,差异有统计学意义(P<0.05)。术后14 d,两组患者脑脊液IL-1β、S-100β水平均下降,且观察组低于对照组,差异有统计学意义(P<0.05)。两组患者术后均出现并发症,但差异无统计学意义(P>0.05)。结论微创术能够有效治疗自发性脑出血灶周水肿,改善脑水肿程度,减轻脑损伤程度,值得临床推广应用。

快速康复外科干预在口腔癌术后口腔皮瓣修复术患者中的应用效果

目的探讨快速康复外科(FTS)干预在口腔癌术后口腔皮瓣修复术患者中的应用效果。方法将2019年1月至2020年5月接受常规干预的49例口腔癌术后口腔皮瓣修复术患者纳入常规组,2020年6月至2022年1月接受FTS干预的49例口腔癌术后口腔皮瓣修复术患者纳入FTS组。比较两组患者的手术相关指标、疼痛程度[视觉模拟评分法(VAS)]、吞咽功能及并发症发生情况。结果FTS组患者引流管拔除时间、恢复进食时间、卧床时间、输液时间、住院时间均明显短于常规组(P﹤0.01)。术后6、24、48、72 h,FTS组患者的VAS评分均明显低于常规组(P﹤0.01)。术后2周,FTS组患者的吞咽功能明显优于常规组(P﹤0.01)。FTS组患者的术后并发症总发生率低于常规组(P﹤0.05)。结论FTS干预可促进口腔癌术后口腔皮瓣修复术患者快速恢复,降低疼痛程度及并发症发生率,改善吞咽功能。