Buerger’s disease, also called thromboangiitis obliterans (TAO), is an inflammatory disease affecting small and medium size blood vessels of the limbs. Several risk factors are strongly associated with this disease. ...Buerger’s disease, also called thromboangiitis obliterans (TAO), is an inflammatory disease affecting small and medium size blood vessels of the limbs. Several risk factors are strongly associated with this disease. In fact, heavy smokers represent 99% of patients diagnosed with Buerger’s disease and smoking cessation can slow down the progression of the pathology. Ulcers and gangrene are very common complications and TAO may also cause a vasculitis as well as ischemic damage to the distal part of the limbs that can eventually lead to limb amputation. Here, we report the case of a 43 years old patient, a flight personnel working in a Tunisian airline company who consults for a lesion of the left toe that appeared 2 weeks ago. He is a chronic inveterate smoker with 36 pack-years. The diagnosis of TAO was made based on the clinical presentation and the results of the Doppler Ultrasound of the left toe. This disease has a major impact on the quality of life due to the risk of necrotic ulcers and amputation. Navigation is a profession that requires a high level of physical and mental fitness. According to the international and Tunisian standards, the applicant or the holder of medical certificate must not have a cardiovascular condition that may affect the safety of the exercise.展开更多
目的 分析某军飞行人员糖尿病前期(PDM)流行现状,为糖尿病(DM)的防控提供参考依据。方法 采取整群抽样法随机抽取2018年4月至10月在某军两所特勤疗养中心疗养的飞行人员1 092人。设计调查问卷,收集飞行机种、人员类别、年龄、吸烟史、D...目的 分析某军飞行人员糖尿病前期(PDM)流行现状,为糖尿病(DM)的防控提供参考依据。方法 采取整群抽样法随机抽取2018年4月至10月在某军两所特勤疗养中心疗养的飞行人员1 092人。设计调查问卷,收集飞行机种、人员类别、年龄、吸烟史、DM家族史,同时测量受调查者血压、身高、体质量,计算体质量指数(BMI),抽取受调查者空腹肘静脉血,检测空腹血糖(FPG)及服用75 g葡萄糖粉负荷后2 h血糖(2 h PG)水平。结果 飞行人员中PDM的患病率为7.05%(77/1 092),其中空腹血糖受损(IFG)、糖耐量减低(IGT)及IFG合并IGT所占比例分别为27.27%(21/77)、68.83%(53/77)和3.90%(3/77)。不同年龄组的比较显示,20~30岁、>30~40岁、>40~50岁和>50岁飞行人员的PDM患病率分别为3.35%(6/179)、5.98%(30/502)、9.68%(27/279)、11.29%(14/124),各组PDM患病率(P<0.05)、FPG及糖负荷后2 h PG均具有统计学差异(P<0.01),随着年龄的增长,PDM患病率、FPG及2 h PG均逐渐上升。根据BMI将飞行人员分为正常、超重和肥胖组,三组PDM患病率分别为4.35%(20/460)、9.92%(50/554)、11.11%(7/70),差异具有统计学意义(P<0.05),PDM患病率及FPG、2 h PG血糖随着BMI的增大逐渐升高。不同机种(歼击机、轰炸机、直升机、运输机、无人机)飞行人员、不同人员类别飞行人员(飞行员、技勤或战勤人员)PDM患病率无显著差异(P>0.05)。与血糖正常的飞行人员相比,PDM组具有年龄大,BMI、FPG、糖负荷后2 h PG高的特点(P<0.05)。结论 PDM飞行人员以IGT为主,随着年龄的增加及BMI的增大,飞行人员PDM患病率及FPG、糖负荷后2 h PG水平逐步升高。对于年龄超过40岁或体型为超重、肥胖的飞行人员,应当有针对性地进行糖耐量筛查,做好DM防控工作。展开更多
文摘Buerger’s disease, also called thromboangiitis obliterans (TAO), is an inflammatory disease affecting small and medium size blood vessels of the limbs. Several risk factors are strongly associated with this disease. In fact, heavy smokers represent 99% of patients diagnosed with Buerger’s disease and smoking cessation can slow down the progression of the pathology. Ulcers and gangrene are very common complications and TAO may also cause a vasculitis as well as ischemic damage to the distal part of the limbs that can eventually lead to limb amputation. Here, we report the case of a 43 years old patient, a flight personnel working in a Tunisian airline company who consults for a lesion of the left toe that appeared 2 weeks ago. He is a chronic inveterate smoker with 36 pack-years. The diagnosis of TAO was made based on the clinical presentation and the results of the Doppler Ultrasound of the left toe. This disease has a major impact on the quality of life due to the risk of necrotic ulcers and amputation. Navigation is a profession that requires a high level of physical and mental fitness. According to the international and Tunisian standards, the applicant or the holder of medical certificate must not have a cardiovascular condition that may affect the safety of the exercise.
文摘目的 分析某军飞行人员糖尿病前期(PDM)流行现状,为糖尿病(DM)的防控提供参考依据。方法 采取整群抽样法随机抽取2018年4月至10月在某军两所特勤疗养中心疗养的飞行人员1 092人。设计调查问卷,收集飞行机种、人员类别、年龄、吸烟史、DM家族史,同时测量受调查者血压、身高、体质量,计算体质量指数(BMI),抽取受调查者空腹肘静脉血,检测空腹血糖(FPG)及服用75 g葡萄糖粉负荷后2 h血糖(2 h PG)水平。结果 飞行人员中PDM的患病率为7.05%(77/1 092),其中空腹血糖受损(IFG)、糖耐量减低(IGT)及IFG合并IGT所占比例分别为27.27%(21/77)、68.83%(53/77)和3.90%(3/77)。不同年龄组的比较显示,20~30岁、>30~40岁、>40~50岁和>50岁飞行人员的PDM患病率分别为3.35%(6/179)、5.98%(30/502)、9.68%(27/279)、11.29%(14/124),各组PDM患病率(P<0.05)、FPG及糖负荷后2 h PG均具有统计学差异(P<0.01),随着年龄的增长,PDM患病率、FPG及2 h PG均逐渐上升。根据BMI将飞行人员分为正常、超重和肥胖组,三组PDM患病率分别为4.35%(20/460)、9.92%(50/554)、11.11%(7/70),差异具有统计学意义(P<0.05),PDM患病率及FPG、2 h PG血糖随着BMI的增大逐渐升高。不同机种(歼击机、轰炸机、直升机、运输机、无人机)飞行人员、不同人员类别飞行人员(飞行员、技勤或战勤人员)PDM患病率无显著差异(P>0.05)。与血糖正常的飞行人员相比,PDM组具有年龄大,BMI、FPG、糖负荷后2 h PG高的特点(P<0.05)。结论 PDM飞行人员以IGT为主,随着年龄的增加及BMI的增大,飞行人员PDM患病率及FPG、糖负荷后2 h PG水平逐步升高。对于年龄超过40岁或体型为超重、肥胖的飞行人员,应当有针对性地进行糖耐量筛查,做好DM防控工作。
