Fluid-attenuated inversion recovery （FLAIR） vascular hyperintensity （FVH） is used to assess leptomeningeal collateral circulation, but clinical outcomes of patients with FVH can be very different. The aim of the p...Fluid-attenuated inversion recovery （FLAIR） vascular hyperintensity （FVH） is used to assess leptomeningeal collateral circulation, but clinical outcomes of patients with FVH can be very different. The aim of the present study was to assess a FVH score and explore its relationship with clinical outcomes. Patients with acute ischemic stroke due to middle cerebral artery M1 occlusion underwent magnetic resonance imaging and were followed up at 10 days （National Institutes of Health Stroke Scale） and 90 days （modified Rankin Scale） to determine short-term clinical outcomes. Effective collateral circulation indirectly improved recovery of neurological function and short-term clinical outcome by extending the size of the pial penumbra and reducing infarct lesions. FVH score showed no correlation with 90-day functional clinical outcome and was not sufficient as an independent predictor of short-term clinical outcome.展开更多
The diagnosis of sporadic Creutzfeldt-Jakob disease （sCJD） is extremely difficult. Diffusion-weighted imaging has been shown to be the most sensitive technique for the detection of signal alterations in sCJD patient...The diagnosis of sporadic Creutzfeldt-Jakob disease （sCJD） is extremely difficult. Diffusion-weighted imaging has been shown to be the most sensitive technique for the detection of signal alterations in sCJD patients. The present study analyzed the diagnostic value of diffusion-weighted imaging and fluid-attenuated inversion recovery sequence in the early stage of sCJD in one female patient and correlated the clinical symptoms during disease course and magnetic resonance manifestations. Thalamic and basal ganglia hyperintensities were observed on magnetic resonance images in a very early stage, i.e., when the clinical typical manifestations of the disease were not present. With the progression of the disease, cortical and basal ganglia hyperintensities were observed on magnetic resonance images, showing an obvious cerebral atrophy. These findings suggest that diffusion-weighted imaging and fluid-attenuated inversion recovery sequence are helpful in diagnosing sCJD.展开更多
目的探讨急性脑梗死(ACI)患者弥散加权成像(DWI)病变体积(VDWI)、T2液体衰减反转恢复序列(T2Flair)病变体积(VFlair)与发病时间的关系,及ACI患者DWI与磁敏感加权成像(SWI)区域显示一致程度与预后的关系。方法选取2019年8月至2021年12月...目的探讨急性脑梗死(ACI)患者弥散加权成像(DWI)病变体积(VDWI)、T2液体衰减反转恢复序列(T2Flair)病变体积(VFlair)与发病时间的关系,及ACI患者DWI与磁敏感加权成像(SWI)区域显示一致程度与预后的关系。方法选取2019年8月至2021年12月包钢集团第三职工医院收治的93例ACI患者作为研究对象。运用线性回归分析VFlair、VDWI的体积差与发病时间(T)的关系,分析DWI图像、SWI图像显示区域一致程度与预后的关系。结果线性回归分析结果显示,症状出现6 h内ACI患者VFlair、VDWI与发病时间(T)存在以下关系:(VFlair−VDWI)/VDWI=−0.573+0.103×T;症状出现6~48 h ACI患者VFlair、VDWI与T存在以下关系:(VFlair−VDWI)/VDWI=−0.049+0.013×T。DWI-SWI图像显示区域一致22例,溶栓有效12例(54.55%);DWI-SWI图像显示区域不一致19例,溶栓有效4例(21.05%),两者比较差异有统计学意义(P<0.05)。结论ACI患者VFlair与VDWI差异能有效预测ACI患者发病时间,DWI-SWI区域显示一致程度能够较好预测ACI患者的预后。展开更多
基金supported by the National Natural Science Foundation of China,No.81371521
文摘Fluid-attenuated inversion recovery （FLAIR） vascular hyperintensity （FVH） is used to assess leptomeningeal collateral circulation, but clinical outcomes of patients with FVH can be very different. The aim of the present study was to assess a FVH score and explore its relationship with clinical outcomes. Patients with acute ischemic stroke due to middle cerebral artery M1 occlusion underwent magnetic resonance imaging and were followed up at 10 days （National Institutes of Health Stroke Scale） and 90 days （modified Rankin Scale） to determine short-term clinical outcomes. Effective collateral circulation indirectly improved recovery of neurological function and short-term clinical outcome by extending the size of the pial penumbra and reducing infarct lesions. FVH score showed no correlation with 90-day functional clinical outcome and was not sufficient as an independent predictor of short-term clinical outcome.
文摘The diagnosis of sporadic Creutzfeldt-Jakob disease （sCJD） is extremely difficult. Diffusion-weighted imaging has been shown to be the most sensitive technique for the detection of signal alterations in sCJD patients. The present study analyzed the diagnostic value of diffusion-weighted imaging and fluid-attenuated inversion recovery sequence in the early stage of sCJD in one female patient and correlated the clinical symptoms during disease course and magnetic resonance manifestations. Thalamic and basal ganglia hyperintensities were observed on magnetic resonance images in a very early stage, i.e., when the clinical typical manifestations of the disease were not present. With the progression of the disease, cortical and basal ganglia hyperintensities were observed on magnetic resonance images, showing an obvious cerebral atrophy. These findings suggest that diffusion-weighted imaging and fluid-attenuated inversion recovery sequence are helpful in diagnosing sCJD.
文摘目的探讨急性脑梗死(ACI)患者弥散加权成像(DWI)病变体积(VDWI)、T2液体衰减反转恢复序列(T2Flair)病变体积(VFlair)与发病时间的关系,及ACI患者DWI与磁敏感加权成像(SWI)区域显示一致程度与预后的关系。方法选取2019年8月至2021年12月包钢集团第三职工医院收治的93例ACI患者作为研究对象。运用线性回归分析VFlair、VDWI的体积差与发病时间(T)的关系,分析DWI图像、SWI图像显示区域一致程度与预后的关系。结果线性回归分析结果显示,症状出现6 h内ACI患者VFlair、VDWI与发病时间(T)存在以下关系:(VFlair−VDWI)/VDWI=−0.573+0.103×T;症状出现6~48 h ACI患者VFlair、VDWI与T存在以下关系:(VFlair−VDWI)/VDWI=−0.049+0.013×T。DWI-SWI图像显示区域一致22例,溶栓有效12例(54.55%);DWI-SWI图像显示区域不一致19例,溶栓有效4例(21.05%),两者比较差异有统计学意义(P<0.05)。结论ACI患者VFlair与VDWI差异能有效预测ACI患者发病时间,DWI-SWI区域显示一致程度能够较好预测ACI患者的预后。
