Fluid-attenuated inversion recovery （FLAIR） vascular hyperintensity （FVH） is used to assess leptomeningeal collateral circulation, but clinical outcomes of patients with FVH can be very different. The aim of the p...Fluid-attenuated inversion recovery （FLAIR） vascular hyperintensity （FVH） is used to assess leptomeningeal collateral circulation, but clinical outcomes of patients with FVH can be very different. The aim of the present study was to assess a FVH score and explore its relationship with clinical outcomes. Patients with acute ischemic stroke due to middle cerebral artery M1 occlusion underwent magnetic resonance imaging and were followed up at 10 days （National Institutes of Health Stroke Scale） and 90 days （modified Rankin Scale） to determine short-term clinical outcomes. Effective collateral circulation indirectly improved recovery of neurological function and short-term clinical outcome by extending the size of the pial penumbra and reducing infarct lesions. FVH score showed no correlation with 90-day functional clinical outcome and was not sufficient as an independent predictor of short-term clinical outcome.展开更多
The diagnosis of sporadic Creutzfeldt-Jakob disease （sCJD） is extremely difficult. Diffusion-weighted imaging has been shown to be the most sensitive technique for the detection of signal alterations in sCJD patient...The diagnosis of sporadic Creutzfeldt-Jakob disease （sCJD） is extremely difficult. Diffusion-weighted imaging has been shown to be the most sensitive technique for the detection of signal alterations in sCJD patients. The present study analyzed the diagnostic value of diffusion-weighted imaging and fluid-attenuated inversion recovery sequence in the early stage of sCJD in one female patient and correlated the clinical symptoms during disease course and magnetic resonance manifestations. Thalamic and basal ganglia hyperintensities were observed on magnetic resonance images in a very early stage, i.e., when the clinical typical manifestations of the disease were not present. With the progression of the disease, cortical and basal ganglia hyperintensities were observed on magnetic resonance images, showing an obvious cerebral atrophy. These findings suggest that diffusion-weighted imaging and fluid-attenuated inversion recovery sequence are helpful in diagnosing sCJD.展开更多
目的探讨不同扫描参数对FLAIR序列金属伪影的影响,以通过调整扫描参数来减小金属伪影。方法选用镍铬合金制成左下6标准桩核冠模型。应用1.5 T MRI扫描仪对桩核冠模型行横断面FLAIR扫描,扫描参数为西门子1.5T MR扫描仪的推荐值。保持其...目的探讨不同扫描参数对FLAIR序列金属伪影的影响,以通过调整扫描参数来减小金属伪影。方法选用镍铬合金制成左下6标准桩核冠模型。应用1.5 T MRI扫描仪对桩核冠模型行横断面FLAIR扫描,扫描参数为西门子1.5T MR扫描仪的推荐值。保持其它参数与标准扫描序列参数一致,逐一改变以下各参数进行成像:TR、TE、FOV、Matrix、BW、NEX、ETL、Thk、FA。确定伪影最大的层面并测量伪影面积。应用SAS V8统计学软件进行统计学分析。结果调整不同FOV值,不同Matrix值及FA值,镍铬合金伪影大小差异有统计学意义(F值分别为F=67.04,F=48.75,F=5.61,P<0.05)。结论在FLAIR序列中,可以通过减小视野、增加矩阵,增大翻转角减小金属伪影。展开更多
基金supported by the National Natural Science Foundation of China,No.81371521
文摘Fluid-attenuated inversion recovery （FLAIR） vascular hyperintensity （FVH） is used to assess leptomeningeal collateral circulation, but clinical outcomes of patients with FVH can be very different. The aim of the present study was to assess a FVH score and explore its relationship with clinical outcomes. Patients with acute ischemic stroke due to middle cerebral artery M1 occlusion underwent magnetic resonance imaging and were followed up at 10 days （National Institutes of Health Stroke Scale） and 90 days （modified Rankin Scale） to determine short-term clinical outcomes. Effective collateral circulation indirectly improved recovery of neurological function and short-term clinical outcome by extending the size of the pial penumbra and reducing infarct lesions. FVH score showed no correlation with 90-day functional clinical outcome and was not sufficient as an independent predictor of short-term clinical outcome.
文摘The diagnosis of sporadic Creutzfeldt-Jakob disease （sCJD） is extremely difficult. Diffusion-weighted imaging has been shown to be the most sensitive technique for the detection of signal alterations in sCJD patients. The present study analyzed the diagnostic value of diffusion-weighted imaging and fluid-attenuated inversion recovery sequence in the early stage of sCJD in one female patient and correlated the clinical symptoms during disease course and magnetic resonance manifestations. Thalamic and basal ganglia hyperintensities were observed on magnetic resonance images in a very early stage, i.e., when the clinical typical manifestations of the disease were not present. With the progression of the disease, cortical and basal ganglia hyperintensities were observed on magnetic resonance images, showing an obvious cerebral atrophy. These findings suggest that diffusion-weighted imaging and fluid-attenuated inversion recovery sequence are helpful in diagnosing sCJD.
文摘目的探讨不同扫描参数对FLAIR序列金属伪影的影响,以通过调整扫描参数来减小金属伪影。方法选用镍铬合金制成左下6标准桩核冠模型。应用1.5 T MRI扫描仪对桩核冠模型行横断面FLAIR扫描,扫描参数为西门子1.5T MR扫描仪的推荐值。保持其它参数与标准扫描序列参数一致,逐一改变以下各参数进行成像:TR、TE、FOV、Matrix、BW、NEX、ETL、Thk、FA。确定伪影最大的层面并测量伪影面积。应用SAS V8统计学软件进行统计学分析。结果调整不同FOV值,不同Matrix值及FA值,镍铬合金伪影大小差异有统计学意义(F值分别为F=67.04,F=48.75,F=5.61,P<0.05)。结论在FLAIR序列中,可以通过减小视野、增加矩阵,增大翻转角减小金属伪影。
