Three hundred and eighty four women in Shanghai who delivered vaginally and chose IUD for contraception received the copper T 380A IUD inserted vaginally within 10 min after delivery of the placenta(i.e.,immediate pos...Three hundred and eighty four women in Shanghai who delivered vaginally and chose IUD for contraception received the copper T 380A IUD inserted vaginally within 10 min after delivery of the placenta(i.e.,immediate postplacental insertion, IPPI). Among them, 98.70% were primipara. The women were randomly divided into two groups: IUD inserted by hand and IUD insreted by ring forceps. Using Life Table Method and χ 2 test, expulsion and other discontinuation rates were compared at 6, 12, 24, and 36 months post insertion between these two different groups. No uterine perforation, infection or prolonged period of lochia occurred in the 384 cases. Expulsions were the main reason for discontinuation. From 6 months to 36 months, the gross cumulative rates of all discontinuation events (expulsion, pregnancy, removal for bleeding/pain, etc.) were not statistically significantly different (P>0.05). The results suggest that these two different insertion techniques do not significantly affect discontinuation rate in vaginal IPPI using the TCu 380 A, which appears to be suitable for postpartum insertion in Chinese women. Other relevant issues, such as breast feeding and IUD position in uterine cavity, are also analyzed and discussed in this paper.展开更多
To study the mechanism of repair of pancreas following acute pancreatitis (AP).Methods NIH Swiss mice were randomized into the saline control group and AP group.AP was induced by intraperitoneal injection of 50 ug/kg ...To study the mechanism of repair of pancreas following acute pancreatitis (AP).Methods NIH Swiss mice were randomized into the saline control group and AP group.AP was induced by intraperitoneal injection of 50 ug/kg body weight cearulein for 4 times,once per hour.The cellular proliferation was detected using flow cytometry.Collagen Ⅰ was detected with immunohistochemistry.Protein zymography was used to evaluate the expression of matrix metalloproteinase-3 (MMP-3).Results In the AP group,the pancreatic lesions were the severest in 8 h and then recovered on the 7th d after induction of AP.Flow cytometry showed that there were three stages of cell proliferation after AP:the active proliferation in early stage,inhibition of proliferation in middle stage and high proliferation in the late stage.The expression level of collage Ⅰ and MMP-3 was markedly higher in the AP group than in the saline control group.Conclusion The pancreas can be repaired after AP.The regeneration mechanism includes intersitial fibrosis and acinar cell replication.7 refs,4 figs.展开更多
文摘Three hundred and eighty four women in Shanghai who delivered vaginally and chose IUD for contraception received the copper T 380A IUD inserted vaginally within 10 min after delivery of the placenta(i.e.,immediate postplacental insertion, IPPI). Among them, 98.70% were primipara. The women were randomly divided into two groups: IUD inserted by hand and IUD insreted by ring forceps. Using Life Table Method and χ 2 test, expulsion and other discontinuation rates were compared at 6, 12, 24, and 36 months post insertion between these two different groups. No uterine perforation, infection or prolonged period of lochia occurred in the 384 cases. Expulsions were the main reason for discontinuation. From 6 months to 36 months, the gross cumulative rates of all discontinuation events (expulsion, pregnancy, removal for bleeding/pain, etc.) were not statistically significantly different (P>0.05). The results suggest that these two different insertion techniques do not significantly affect discontinuation rate in vaginal IPPI using the TCu 380 A, which appears to be suitable for postpartum insertion in Chinese women. Other relevant issues, such as breast feeding and IUD position in uterine cavity, are also analyzed and discussed in this paper.
文摘To study the mechanism of repair of pancreas following acute pancreatitis (AP).Methods NIH Swiss mice were randomized into the saline control group and AP group.AP was induced by intraperitoneal injection of 50 ug/kg body weight cearulein for 4 times,once per hour.The cellular proliferation was detected using flow cytometry.Collagen Ⅰ was detected with immunohistochemistry.Protein zymography was used to evaluate the expression of matrix metalloproteinase-3 (MMP-3).Results In the AP group,the pancreatic lesions were the severest in 8 h and then recovered on the 7th d after induction of AP.Flow cytometry showed that there were three stages of cell proliferation after AP:the active proliferation in early stage,inhibition of proliferation in middle stage and high proliferation in the late stage.The expression level of collage Ⅰ and MMP-3 was markedly higher in the AP group than in the saline control group.Conclusion The pancreas can be repaired after AP.The regeneration mechanism includes intersitial fibrosis and acinar cell replication.7 refs,4 figs.
