Gastric cancer(GC),the third leading cause of cancer-related death globally,is complex and heterogeneous.This review explores multidisciplinary investigations of traditional Chinese medicine(TCM)combined with Western ...Gastric cancer(GC),the third leading cause of cancer-related death globally,is complex and heterogeneous.This review explores multidisciplinary investigations of traditional Chinese medicine(TCM)combined with Western medical practices,emphasizing the development of nutraceuticals for cancer prevention.Using advanced analytical chemistry and food chemistry techniques,this study investigated how TCM components may be optimized for nutraceutical development.Focusing on molecular interactions with GC pathways,particularly the NF-κB,PI3K/Akt,and Wnt/β-catenin pathways,we examined the effects of TCM polyherbal formulas,extracts,and isolated compounds.These agents modulate apoptosis and cellular proliferation,underscoring their potential in preventive strategies.The convergence of nutraceutical and medicine food homology studies highlights a significant shift towards integrating TCM-derived compounds in a preventive health framework.This approach aims not only to enhance efficacy and reduce side effects but also to champion a preventive paradigm using personalized medicine to advance proactive health maintenance and disease prevention.The combination of TCM and western medical practices offers promising avenues for future research and practical applications in GC prevention.展开更多
Carbon-based selenium-containing materials are novel materials just being invented recently.Owing to the low cost and bio-compatible features of carbon and selenium,these materials are practical.The unique chemical-an...Carbon-based selenium-containing materials are novel materials just being invented recently.Owing to the low cost and bio-compatible features of carbon and selenium,these materials are practical.The unique chemical-and bio-activities of selenium endow them wide range of applications in catalysis,environment-protection,fertilizer and biocide development etc.Recent progresses in this field are summarized and prospected from the engineering application viewpoint in this mini-review.展开更多
文摘Gastric cancer(GC),the third leading cause of cancer-related death globally,is complex and heterogeneous.This review explores multidisciplinary investigations of traditional Chinese medicine(TCM)combined with Western medical practices,emphasizing the development of nutraceuticals for cancer prevention.Using advanced analytical chemistry and food chemistry techniques,this study investigated how TCM components may be optimized for nutraceutical development.Focusing on molecular interactions with GC pathways,particularly the NF-κB,PI3K/Akt,and Wnt/β-catenin pathways,we examined the effects of TCM polyherbal formulas,extracts,and isolated compounds.These agents modulate apoptosis and cellular proliferation,underscoring their potential in preventive strategies.The convergence of nutraceutical and medicine food homology studies highlights a significant shift towards integrating TCM-derived compounds in a preventive health framework.This approach aims not only to enhance efficacy and reduce side effects but also to champion a preventive paradigm using personalized medicine to advance proactive health maintenance and disease prevention.The combination of TCM and western medical practices offers promising avenues for future research and practical applications in GC prevention.
基金the Natural Science Foundation of Guangling College(No.ZKZZ18001)Jiangsu Provincial Six Talent Peaks Project(No.XCL-090)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)for financial support。
文摘Carbon-based selenium-containing materials are novel materials just being invented recently.Owing to the low cost and bio-compatible features of carbon and selenium,these materials are practical.The unique chemical-and bio-activities of selenium endow them wide range of applications in catalysis,environment-protection,fertilizer and biocide development etc.Recent progresses in this field are summarized and prospected from the engineering application viewpoint in this mini-review.
