Hepatocellular carcinoma （HCC） is one of the most frequent complications in patients with .liver cirrhosis. HCC without cirrhosis is rareand obviously a different entity. Treatment depends on tumor stage, liver func...Hepatocellular carcinoma （HCC） is one of the most frequent complications in patients with .liver cirrhosis. HCC without cirrhosis is rareand obviously a different entity. Treatment depends on tumor stage, liver function and general performance. Results of locoregional treatment, resection or liver transplantation are superior to those of medical therapy. Surgical approaches are potentially curative. Underlying cirrhosis is usually the limiting factor for the extent of resection and persists after resection. Liver transplantation eliminates both cirrhosis and, potentially, the tumor. Whereas surgery （functional liver capacity provided） may be performed even in advanced tumors, liver transplantation is advocated in less advanced （T2） tumors in order to keep the rate of recurrent tumor low. Responsible use of scarce grafts requires sticking to this rule.展开更多
文摘Hepatocellular carcinoma （HCC） is one of the most frequent complications in patients with .liver cirrhosis. HCC without cirrhosis is rareand obviously a different entity. Treatment depends on tumor stage, liver function and general performance. Results of locoregional treatment, resection or liver transplantation are superior to those of medical therapy. Surgical approaches are potentially curative. Underlying cirrhosis is usually the limiting factor for the extent of resection and persists after resection. Liver transplantation eliminates both cirrhosis and, potentially, the tumor. Whereas surgery （functional liver capacity provided） may be performed even in advanced tumors, liver transplantation is advocated in less advanced （T2） tumors in order to keep the rate of recurrent tumor low. Responsible use of scarce grafts requires sticking to this rule.
