Visualization analysis of the research status of FU Qingzhu’s Obstetrics and Gynecology based on bibliometrics

Objective This study examined the research status and development process of FU Qingzhu’s Obstetrics and Gynecology(Fu Qing Zhu Nv Ke,《傅青主女科》,FQZNK)in the past 40 years with bibliometrics and visual analysis.Methods Retrieved all related literature in the research field of FQZNK from the domestic and foreign databases:China National Knowledge Infrastructure(CNKI),China Science and Technology Journal Database(VIP),Wanfang Database,and Web of Science(WOS)core database,including Science Citation Index Expanded(SCIE),Social Sciences Citation Index(SSCI),and Arts&Humanities Citation Index(A&HCI).The search range was from January 1,1980 to March 10,2021.In addition,bibliometrics and CiteSpace 5.7.R2 software were used to analyze literature types,published journals,cited literature,the number of author publica-tions,co-author networks,co-institution networks,keyword co-occurrence networks,keyword clusters,and keyword bursts.Results A total of 678 valid records were included in the final dataset.Literature types,high publication journals,highly cited literature,high-yield institutions,high-yield research teams,and high-productivity scholars in this research field were found through bibliometrics.Liter-ature types can be divided into four categories,among which 451 are theoretical studies on academic thoughts of FQZNK,accounting for 66.5%of the included journals.The Journal of Shanxi Traditional Chinese Medicine had the largest volume of published articles(61),ac-counting for 9.0%of the total number of the included journals.The most cited literature was ZHOU Mingxin’s article“Using the quantitative method to discuss author’s authenticity and formula characteristics of FU Qingzhu’s Obstetrics and Gynecology”,which was cited 94 times.Hunan University of Chinese Medicine,the institution with the most publications,published 45 articles,and YOU Zhaoling,the most published author,published 33 articles.Moreover,it was found that most high-yield researchers came from high-yield institutions and that Hun-an University of Chinese Medicine had the most research on FQZNK.Keyword co-occur-rence analysis revealed that the keyword“FQZNK”had the highest frequency(597 times)and the highest centrality(1.00).Keyword cluster analysis used the Log-Likelihood Ratio(LLR)al-gorithm to form eleven important clusters:#0 treatment aiming at its root causes,#1 gynecopathy,#2 Siwu Decoction(四物汤),#3 FU Qingzhu,#4 post-partum,#5 infertility,#6 dysmenorrhea,#7 sterility,#8 coordinate the heart and kidney,#9 Danggui Buxue Decoction(当归补血汤),and#10 treatment.It was found that the prescriptions of FQZNK were studied mainly before 2000,the theoretical studies were mainly conducted before 2010,and its clinic-al application was mainly explored from 2010 until now.Diseases such as dysmenorrhea,morbid vaginal discharge,infertility,metrorrhagia,and polycystic ovarian syndrome(PCOS)have recently become popular topics in this field.Conclusion The current study provides more scientific,accurate,and comprehensive sci-entific support for further research and development of traditional Chinese medicine(TCM)in FQZNK.With this foundation,people can use burst detection to ascertain the current hot-spots in research,get their development trends,and forecast future research directions.In ad-dition,infertility,morbid vaginal discharge,flooding,and PCOS treatments based on TCM syndrome differentiation are currently popular research topics for FQZNK.

《傅青主女科》化裁应用四物汤拾粹

四物汤源于唐代《仙授理伤续断秘方》,《太平惠民和剂局方》将四物汤列于“治妇人诸疾”后为治疗妇科疾病的主方,有“妇科第一方”之称。《傅青主女科》为明末清初医家傅青主所著,傅氏根据女性不同时期的生理特点对四物汤进行化裁加减,灵活运用于妇人诸疾中,取得良好的临床疗效。笔者整理《傅青主女科》所载151首方剂,四物汤原方的方剂共7首,化裁四物汤取其3药的方剂共29首。总结四物汤化裁应用特点有:(1)补益气血,使胞宫充荣。(2)养血柔肝,顺肝气之逆,解五脏之郁:疏肝郁以解肾郁,滋肾水以润肝木;调畅气机,使水火既济;疏肝健脾,通络下乳;柔肝解郁,培土宁心,宣通肾气以调经。(3)补血以缓急宽带,利腰脐之气。

《傅青主女科》“病-证-症”模式对高泌乳素血症导致排卵障碍性不孕的指导

该文基于《傅青主女科》“病-证-症”模式,探讨其对高泌乳素血症(HPRL)导致排卵障碍性不孕的指导意义。《傅青主女科》以病种提纲挈领,抓住主症,分析病机,辨证遣方,体现了“病-证-症”模式,核心在于“病证结合”。其《调经篇》《种子篇》对后世现代医家在不孕病的诊疗中具有重要的参考意义,其中诸多方药被沿用至今,效果颇佳。中医认为HPRL的发病机制主要在于肾虚、肝郁2个方面,其中肾虚为主要原因,肝郁加速高泌乳素血症发病,用药多以补肾疏肝为主。《傅青主女科》中“病-证-症”模式对HPRL导致排卵障碍性不孕的诊疗具有重要意义,即不拘泥于病种和证型,以“病-证-症”结合,突出患者主诉,抓住主要病机,病证结合,发挥整体观优势辨证施治。《傅青主女科》中诸多疾病如嫉妒不孕、肥胖不孕、经水后期、经水数月一行、经水先后无定期等,虽未提HPRL典型的泌乳症状,仍可根据主诉、证型、症状参考治法用药,弥补了现代中医过度依赖血清生化指标的缺陷,其重视肝脾肾心、整体观以及扶正祛邪的诊疗思想值得借鉴。