Background:COVID-19 has been impacting on the whole world critically and constantly since late December 2019.Rapidly increasing infections has raised intense worldwide attention.How to model the evolution of COVID-19 ...Background:COVID-19 has been impacting on the whole world critically and constantly since late December 2019.Rapidly increasing infections has raised intense worldwide attention.How to model the evolution of COVID-19 effectively and efficiently is of great significance for prevention and control.Methods:We propose the multi-chain Fudan-CCDC model based on the original single-chain model in[Shao et al.2020]to describe the evolution of COVID-19 in Singapore.Multi-chains can be considered as the superposition of several single chains with different characteristics.We identify the parameters of models by minimizing the penalty function.Results:The numerical simulation results exhibit the multi-chain model performs well on data fitting.Though unsteady the increments are,they could still fall within the range of±30%fluctuation from simulation results.Conclusion:The multi-chain Fudan-CCDC model provides an effective way to early detect the appearance of imported infectors and super spreaders and forecast a second outbreak.It can also explain the data from those countries where the single-chain model shows deviation from the data.展开更多
基金the National Natural Science Foundation of China(No.11671098)partially supported by Shanghai Science and technology research program(No.19JC1420101)+1 种基金J.C.is supported in part by the National Natural Science Foundation of China(No.11971121)Y.Y.is supported by Shanghai Sailing Program(No.20YF1412400).
文摘Background:COVID-19 has been impacting on the whole world critically and constantly since late December 2019.Rapidly increasing infections has raised intense worldwide attention.How to model the evolution of COVID-19 effectively and efficiently is of great significance for prevention and control.Methods:We propose the multi-chain Fudan-CCDC model based on the original single-chain model in[Shao et al.2020]to describe the evolution of COVID-19 in Singapore.Multi-chains can be considered as the superposition of several single chains with different characteristics.We identify the parameters of models by minimizing the penalty function.Results:The numerical simulation results exhibit the multi-chain model performs well on data fitting.Though unsteady the increments are,they could still fall within the range of±30%fluctuation from simulation results.Conclusion:The multi-chain Fudan-CCDC model provides an effective way to early detect the appearance of imported infectors and super spreaders and forecast a second outbreak.It can also explain the data from those countries where the single-chain model shows deviation from the data.