As an important part of nonstructural components,the seismic response of indoor water supply pipes deserves much attention.This paper presents shaking table test research on water supply pipes installed in a full-scal...As an important part of nonstructural components,the seismic response of indoor water supply pipes deserves much attention.This paper presents shaking table test research on water supply pipes installed in a full-scale reinforced concrete(RC)frame structure.Different material pipes and different methods for penetrating the reinforced concrete floors are combined to evaluate the difference in seismic performance.Floor response spectra and pipe acceleration amplification factors based on test data are discussed and compared with code provisions.A seismic fragility study of displacement demand is conducted based on numerical simulation.The acceleration response and displacement response of different combinations are compared.The results show that the combination of different pipe materials and different passing-through methods can cause obvious differences in the seismic response of indoor riser pipes.展开更多
Cellular thin-shell structures are widely applied in ultralightweight designs due to their high bearing capacity and strength-to-weight ratio.In this paper,a full-scale isogeometric topology optimization(ITO)method ba...Cellular thin-shell structures are widely applied in ultralightweight designs due to their high bearing capacity and strength-to-weight ratio.In this paper,a full-scale isogeometric topology optimization(ITO)method based on Kirchhoff-Love shells for designing cellular tshin-shell structures with excellent damage tolerance ability is proposed.This method utilizes high-order continuous nonuniform rational B-splines(NURBS)as basis functions for Kirchhoff-Love shell elements.The geometric and analysis models of thin shells are unified by isogeometric analysis(IGA)to avoid geometric approximation error and improve computational accuracy.The topological configurations of thin-shell structures are described by constructing the effective density field on the controlmesh.Local volume constraints are imposed in the proximity of each control point to obtain bone-like cellular structures.To facilitate numerical implementation,the p-norm function is used to aggregate local volume constraints into an equivalent global constraint.Several numerical examples are provided to demonstrate the effectiveness of the proposed method.After simulation and comparative analysis,the results indicate that the cellular thin-shell structures optimized by the proposed method exhibit great load-carrying behavior and high damage robustness.展开更多
In order to provide more insights into the damage propagation composite wind turbine blades(blade)under cyclic fatigue loading,a stiffness degradation model for blade is proposed based on the full-scale fatigue testin...In order to provide more insights into the damage propagation composite wind turbine blades(blade)under cyclic fatigue loading,a stiffness degradation model for blade is proposed based on the full-scale fatigue testing of a blade.A novel non-linear fatigue damage accumulation model is proposed using the damage assessment theories of composite laminates for the first time.Then,a stiffness degradation model is established based on the correlation of fatigue damage and residual stiffness of the composite laminates.Finally,a stiffness degradation model for the blade is presented based on the full-scale fatigue testing.The scientific rationale of the proposed stiffness model of blade is verified by using full-scale fatigue test data of blade with a total length of 52.5 m.The results indicate that the proposed stiffness degradation model of the blade agrees well with the fatigue testing results of this blade.This work provides a basis for evaluating the fatigue damage and lifetime of blade under cyclic fatigue loading.展开更多
Rock anchors are a common safety measure for stabilising large-scale infrastructure,such as bridge towers,retaining walls,rock slopes and windmills.There are four principal failure modes for rock anchors:(a)tensile fa...Rock anchors are a common safety measure for stabilising large-scale infrastructure,such as bridge towers,retaining walls,rock slopes and windmills.There are four principal failure modes for rock anchors:(a)tensile failure of the steel anchor,(b)anchor-grout interface failure,(c)grout-rock interface failure,and(d)rock mass uplift.Field tests were performed in a limestone quarry.These tests were designed to test failure modes B and C through pullout.In the tests of failure mode B,the shear stress on the anchor-grout interface is the largest at the top of the grout column and attenuates towards the distal end for small loads.The shear stress becomes uniformly distributed when the applied load is approximately 50%of the ultimate pullout load.The anchors designed to test failure mode C were installed with an endplate and had a higher toughness than the straight bar anchors.The shear stress on the grout-rock interface is the largest at the endplate and attenuates upward before slip starts along the interface.When the ultimate pullout load is reached,and the grout column starts to slip,the shear stress is approximately constant.The bond shear strength on the anchor-grout interface was approximately 20%of the uniaxial compressive strength of the grout,and the bond strength of the grout-rock interface was around 5%for that of the grout.The grout-rock interface is likely determined by whichever is weaker,the grout or the rock.展开更多
Computational fluid dynamics(CFD)provides a powerful tool for investigating complicated fluid flows.This paper aims to study the applicability of CFD in the preliminary design of linear and nonlinear fluid viscous dam...Computational fluid dynamics(CFD)provides a powerful tool for investigating complicated fluid flows.This paper aims to study the applicability of CFD in the preliminary design of linear and nonlinear fluid viscous dampers.Two fluid viscous dampers were designed based on CFD models.The first device was a linear viscous damper with straight orifices.The second was a nonlinear viscous damper containing a one-way pressure-responsive valve inside its orifices.Both dampers were detailed based on CFD simulations,and their internal fluid flows were investigated.Full-scale specimens of both dampers were manufactured and tested under dynamic loads.According to the tests results,both dampers demonstrate stable cyclic behaviors,and as expected,the nonlinear damper generally tends to dissipate more energy compared to its linear counterpart.Good compatibility was achieved between the experimentally measured damper force-velocity curves and those estimated from CFD analyses.Using a thermography camera,a rise in temperature of the dampers was measured during the tests.It was found that output force of the manufactured devices was virtually independent of temperature even during long duration loadings.Accordingly,temperature dependence can be ignored in CFD models,because a reliable temperature compensator mechanism was used(or intended to be used)by the damper manufacturer.展开更多
The monopile is the most common foundation to support offshore wind turbines.In the marine environment,local scour due to combined currents and waves is a significant issue that must be considered in the design of win...The monopile is the most common foundation to support offshore wind turbines.In the marine environment,local scour due to combined currents and waves is a significant issue that must be considered in the design of wind turbine foundations.In this paper,a full-scale numerical model was developed and validated based on field data from Rudong,China.The scour development around monopiles was investigated,and the effects of waves and the Reynolds number Re were analyzed.Several formulas for predicting the scour depth in the literature have been evaluated.It is found that waves can accelerate scour development even if the KC number is small(0.78<KC<1.57).The formula obtained from small-scale model tests may be unsafe or wasteful when it is applied in practical design due to the scale effect.A new equation for predicting the scour depth based on the average pile Reynolds number(Rea)is proposed and validated with field data.The equilibrium scour depth predicted using the proposed equation is evaluated and compared with those from nine equations in the literature.It is demonstrated that the values predicted from the proposed equation and from the S/M(Sheppard/Melville)equation are closer to the field data.展开更多
Driven by the concept of agricultural sustainable development,crop planting structure optimization(CPSO)has become an effective measure to reduce regional crop water demand,ensure food security,and protect the environ...Driven by the concept of agricultural sustainable development,crop planting structure optimization(CPSO)has become an effective measure to reduce regional crop water demand,ensure food security,and protect the environment.However,traditional optimization of crop planting structures often ignores the impact on regional food supply–demand relations and interprovincial food trading.Therefore,using a system analysis concept and taking virtual water output as the connecting point,this study proposes a theoretical CPSO framework based on a multi-aspect and full-scale evaluation index system.To this end,a water footprint(WF)simulation module denoted as soil and water assessment tool–water footprint(SWAT-WF)is constructed to simulate the amount and components of regional crop WFs.A multi-objective spatial CPSO model with the objectives of maximizing the regional economic water productivity(EWP),minimizing the blue water dependency(BWFrate),and minimizing the grey water footprint(GWFgrey)is established to achieve an optimal planting layout.Considering various benefits,a fullscale evaluation index system based on region,province,and country scales is constructed.Through an entropy weight technique for order preference by similarity to an ideal solution(TOPSIS)comprehensive evaluation model,the optimal plan is selected from a variety of CPSO plans.The proposed framework is then verified through a case study of the upper–middle reaches of the Heihe River Basin in Gansu province,China.By combining the theory of virtual water trading with system analysis,the optimal planting structure is found.While sacrificing reasonable regional economic benefits,the optimization of the planting structure significantly improves the regional water resource benefits and ecological benefits at different scales.展开更多
Motivated by the huge practical engineering demand for the fundamental understanding of mechanical characteristics of high-speed railway infrastructure,a fullscale multi-functional test platform for high-speed railway...Motivated by the huge practical engineering demand for the fundamental understanding of mechanical characteristics of high-speed railway infrastructure,a fullscale multi-functional test platform for high-speed railway track–subgrade system is developed in this paper,and its main functions for investigating the mechanical performance of track–subgrade systems are elaborated with three typical experimental examples.Comprising the full-scale subgrade structure and all the five types of track structures adopted in Chinese high-speed railways,namely the CRTS I,the CRTS II and the CRTS III ballastless tracks,the double-block ballastless track and the ballasted track,the test platform is established strictly according to the construction standard of Chinese high-speed railways.Three kinds of effective loading methods are employed,including the real bogie loading,multi-point loading and the impact loading.Various types of sensors are adopted in different components of the five types of track–subgrade systems to measure the displacement,acceleration,pressure,structural strain and deformation,etc.Utilizing this test platform,both dynamic characteristics and long-term performance evolution of high-speed railway track–subgrade systems can be investigated,being able to satisfy the actual demand for large-scale operation of Chinese high-speed railways.As examples,three typical experimental studies are presented to elucidate the comprehensive functionalities of the full-scale multi-functional test platform for exploring the dynamic performance and its long-term evolution of ballastless track systems and for studying the long-term accumulative settlement of the ballasted track–subgrade system in high-speed railways.Some interesting phenomena and meaningful results are captured by the developed test platform,which provide a useful guidance for the scientific operation and maintenance of high-speed railway infrastructure.展开更多
Lining materials are widely used in buildings to cover walls and ceilings. Combustible linings may produce a potential high fire hazard in buildings. Once ignited,it propagates fire and accelerates the enclosure fire ...Lining materials are widely used in buildings to cover walls and ceilings. Combustible linings may produce a potential high fire hazard in buildings. Once ignited,it propagates fire and accelerates the enclosure fire growth. Two types of lining materials were studied during the tests:block board and plywood. The test was conducted in an ISO 9705 room,where linings were mounted on walls without the ceiling. By changing the heat output of the burner,the ventilation,etc.,the concentrations of CO2/CO of different lining materials were researched. The effect of test conditions on the production of CO2/CO of different lining materials was investigated,and useful experimental data were provided for the further development of numerical modeling to simulate enclosure fire growth lined with combusti-ble materials.展开更多
Confining stresses serve as a pivotal determinant in shaping the behavior of grouted rock bolts.Nonetheless,prior investigations have oversimplified the three-dimensional stress state,primarily assuming hydrostatic st...Confining stresses serve as a pivotal determinant in shaping the behavior of grouted rock bolts.Nonetheless,prior investigations have oversimplified the three-dimensional stress state,primarily assuming hydrostatic stress conditions.Under these conditions,it is assumed that the intermediate principal stress(σ_(2))equals the minimum principal stress(σ_(3)).This assumption overlooks the potential variations in magnitudes of in situ stress conditions along all three directions near an underground opening where a rock bolt is installed.In this study,a series of push tests was meticulously conducted under triaxial conditions.These tests involved applying non-uniform confining stresses(σ_(2)≠σ_(3))to cubic specimens,aiming to unveil the previously overlooked influence of intermediate principal stresses on the strength properties of rock bolts.The results show that as the confining stresses increase from zero to higher levels,the pre-failure behavior changes from linear to nonlinear forms,resulting in an increase in initial stiffness from 2.08 kN/mm to 32.51 kN/mm.The load-displacement curves further illuminate distinct post-failure behavior at elevated levels of confining stresses,characterized by enhanced stiffness.Notably,the peak load capacity ranged from 27.9 kN to 46.5 kN as confining stresses advanced from σ_(2)=σ_(3)=0 to σ_(2)=20 MPa and σ_(3)=10 MPa.Additionally,the outcomes highlight an influence of confining stress on the lateral deformation of samples.Lower levels of confinement prompt overall dilation in lateral deformation,while higher confinements maintain a state of shrinkage.Furthermore,diverse failure modes have been identified,intricately tied to the arrangement of confining stresses.Lower confinements tend to induce a splitting mode of failure,whereas higher loads bring about a shift towards a pure interfacial shear-off and shear-crushed failure mechanism.展开更多
Edge devices,due to their limited computational and storage resources,often require the use of compilers for program optimization.Therefore,ensuring the security and reliability of these compilers is of paramount impo...Edge devices,due to their limited computational and storage resources,often require the use of compilers for program optimization.Therefore,ensuring the security and reliability of these compilers is of paramount importance in the emerging field of edge AI.One widely used testing method for this purpose is fuzz testing,which detects bugs by inputting random test cases into the target program.However,this process consumes significant time and resources.To improve the efficiency of compiler fuzz testing,it is common practice to utilize test case prioritization techniques.Some researchers use machine learning to predict the code coverage of test cases,aiming to maximize the test capability for the target compiler by increasing the overall predicted coverage of the test cases.Nevertheless,these methods can only forecast the code coverage of the compiler at a specific optimization level,potentially missing many optimization-related bugs.In this paper,we introduce C-CORE(short for Clustering by Code Representation),the first framework to prioritize test cases according to their code representations,which are derived directly from the source codes.This approach avoids being limited to specific compiler states and extends to a broader range of compiler bugs.Specifically,we first train a scaled pre-trained programming language model to capture as many common features as possible from the test cases generated by a fuzzer.Using this pre-trained model,we then train two downstream models:one for predicting the likelihood of triggering a bug and another for identifying code representations associated with bugs.Subsequently,we cluster the test cases according to their code representations and select the highest-scoring test case from each cluster as the high-quality test case.This reduction in redundant testing cases leads to time savings.Comprehensive evaluation results reveal that code representations are better at distinguishing test capabilities,and C-CORE significantly enhances testing efficiency.Across four datasets,C-CORE increases the average of the percentage of faults detected(APFD)value by 0.16 to 0.31 and reduces test time by over 50% in 46% of cases.When compared to the best results from approaches using predicted code coverage,C-CORE improves the APFD value by 1.1% to 12.3% and achieves an overall time-saving of 159.1%.展开更多
The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an ...The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an excellent test for stateof-the-art nuclear models.The atomic nucleus is a self-organized quantum manybody system comprising specific numbers of protons Z and neutrons N.展开更多
BACKGROUND Helicobacter pylori(H.pylori)infection has been well-established as a significant risk factor for several gastrointestinal disorders.The urea breath test(UBT)has emerged as a leading non-invasive method for...BACKGROUND Helicobacter pylori(H.pylori)infection has been well-established as a significant risk factor for several gastrointestinal disorders.The urea breath test(UBT)has emerged as a leading non-invasive method for detecting H.pylori.Despite numerous studies confirming its substantial accuracy,the reliability of UBT results is often compromised by inherent limitations.These findings underscore the need for a rigorous statistical synthesis to clarify and reconcile the diagnostic accuracy of the UBT for the diagnosis of H.pylori infection.AIM To determine and compare the diagnostic accuracy of 13C-UBT and 14C-UBT for H.pylori infection in adult patients with dyspepsia.METHODS We conducted an independent search of the PubMed/MEDLINE,EMBASE,and Cochrane Central databases until April 2022.Our search included diagnostic accuracy studies that evaluated at least one of the index tests(^(13)C-UBT or ^(14)C-UBT)against a reference standard.We used the QUADAS-2 tool to assess the methodo-logical quality of the studies.We utilized the bivariate random-effects model to calculate sensitivity,specificity,positive and negative test likelihood ratios(LR+and LR-),as well as the diagnostic odds ratio(DOR),and their 95%confidence intervals.We conducted subgroup analyses based on urea dosing,time after urea administration,and assessment technique.To investigate a possible threshold effect,we conducted Spearman correlation analysis,and we generated summary receiver operating characteristic(SROC)curves to assess heterogeneity.Finally,we visually inspected a funnel plot and used Egger’s test to evaluate publication bias.endorsing both as reliable diagnostic tools in clinical practice.CONCLUSION In summary,our study has demonstrated that ^(13)C-UBT has been found to outperform the ^(14)C-UBT,making it the preferred diagnostic approach.Additionally,our results emphasize the significance of carefully considering urea dosage,assessment timing,and measurement techniques for both tests to enhance diagnostic precision.Nevertheless,it is crucial for researchers and clinicians to evaluate the strengths and limitations of our findings before implementing them in practice.展开更多
Screening for maternal syphilis has been an essential component of routine antenatal screening tests in most countries for many years. This is not only because of the virulence of the spirochete which causes the infec...Screening for maternal syphilis has been an essential component of routine antenatal screening tests in most countries for many years. This is not only because of the virulence of the spirochete which causes the infection but also because of its vertical transmission rate and the potential severe adverse complications/morbidity that can result from its transmission to the fetus. Although the incidence of maternal syphilis and its fetal sequalae in low-income countries has been considerable for several years, the disease has been almost non-existent in high income countries with wide antenatal screening coverage and effective treatment programmes for Syphilis. The recent alarming increase in the incidence of maternal syphilis in high income countries has spawned a renewed public health interest in the infection, with several countries updating and strengthening public health guidance in an attempt to stem this dramatic trend. This is a short clinical update for the practising obstetrician on how to manage the antenatal patient with a positive syphilis screening test.展开更多
The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction ...The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future.展开更多
Since the beginning of COVID-19 pandemics many countries were facing challenges with testing capacity recourse limitations. Throughout the waves of the pandemic countries were trying to address the existing constrains...Since the beginning of COVID-19 pandemics many countries were facing challenges with testing capacity recourse limitations. Throughout the waves of the pandemic countries were trying to address the existing constrains exploring solutions to increase the testing capacity with more cost-effective approaches. Pooled methodology was one of the methods which many have validated and used. It is evident that in case of pooled sample testing the sensitivity becomes lower, however the variation highly depends on the pool size as well as the incidence rate at the certain point. Armenia as well as many other countries has adopted regulations for mandatory COVID-19 PCR testing for all the travelers. Current study aimed to explore the efficiency of COVID-19 pooled PCR testing for nasopharyngeal swabs of individuals with no symptoms in a time period with good epidemiological state of the infection. Nasopharingeal swab samples from individuals were collected. The manual extraction of RNAs of samples was performed after pooling up to 5 samples. The pools with Cycle Threshold (CT) of < 37 were considered positive and were retested individually. In total 28,015 samples were grouped in 667 pools of which 57 were positive. The total number of positive samples was 65. The median difference (CT-pool–CT samples) was 2.4 (ranging from–3.0 to 8.9). The correlation of CT of pools and positive samples was positive. The correlation coefficient r = 0.84, P < 0.000, 95% CI range 0.7423 to 0.9243). The total economic saving when using pools compared to the individual testing was 72%. The minor difference between CT values of pools and samples can be explained by the dilution effect in the pool. However, the positive correlation between the values as well as the amount of cost saving demonstrate that pooling on nasopharyngeal samples for COVID-19 PCR testing can be a good method for efficient screening with significant resource saving. One of the most important advantages of the proposed method is the fact that samples are pooled prior extraction, which avoids the possibilities with misinterpretation of IC due to low yield of RNA in the extraction process.展开更多
The test of Prentice [1] is a non-parametric statistical test for the two-way analysis of variance using ranks. The null distribution of this test typically is approximated using the Chi-square distribution. However, ...The test of Prentice [1] is a non-parametric statistical test for the two-way analysis of variance using ranks. The null distribution of this test typically is approximated using the Chi-square distribution. However, the exact null distribution deviates from the Chi-square approximation in certain cases commonly found in applications of the test, motivating adjustments to the distribution. This manuscript presents adjustments to this null distribution correcting for continuity, multivariate skewness, and multivariate kurtosis. The effects of alternative scoring methods as non-polynomial functions of rank sums are also presented as a broader application of the approximation.展开更多
Introduction: Exercise stress testing (on a treadmill or ergometer bicycle) is an important test in cardiology for diagnosing myocardial ischemia. This test in Mali is still in its beginning compared to other countrie...Introduction: Exercise stress testing (on a treadmill or ergometer bicycle) is an important test in cardiology for diagnosing myocardial ischemia. This test in Mali is still in its beginning compared to other countries in the sub-region. The lack of data in Mali prompted this study, which aimed to evaluate the indications of this activity and its diagnostic contribution to cardiology in Mali. Materials and Methods: This was a retrospective, descriptive study. The study was conducted at the “TOUCAM” medical clinic in Kati based on the analysis of stress test reports between January 2016 and August 2022. Result: During the study period, we documented 73 patients who underwent exercise testing on a bicycle ergometer for suspected coronary heart disease. The mean age of our patients was 47.5 ± 13.8 years (14 and 79 years). Males accounted for the majority (78.1%). The sex ratio is 3.5. More than half of our patients were overweight or obese (77.1%). Hypertension and diabetes affected 52.1% and 25.8% of patients, respectively. 20.8% of patients had coronary artery disease. renin-angiotensin-aldosterone system blockers (56.8%) and beta-blockers (51.3%). The main indications were chest pain (63.0%) and ischemia detection (15.1%). A modified STEEP protocol was used. The majority of our patients (71.2%) achieved at least 85% of their maximum theoretical heart rate. The main reason for the termination of the study was fatigue (57.3%). The average duration was 11.3 ± 4.2 minutes. 24.7% thought the stress tests were positive and 17.8% thought they were controversial. Conclusion: This study demonstrates the importance of stress testing in the diagnosis and treatment of ischemic heart disease, especially in settings where we have very limited access to coronary angiography.展开更多
A new dual-actuator fatigue loading system of wind turbine blades was designed.Compared with the traditional pendulum loading mode,the masses in this system only moved linearly along the loading direction to increase ...A new dual-actuator fatigue loading system of wind turbine blades was designed.Compared with the traditional pendulum loading mode,the masses in this system only moved linearly along the loading direction to increase the exciting force.However,the two actuators and the blade constituted a complicated non-linear energy transferring system,which led to the non-synchronization of actuators.On-site test results showed that the virtual spindle synchronous strategy commonly used in synchronous control was undesirable and caused the instability of the blade’s amplitude eventually.A cross-coupled control strategy based on the active disturbance rejection algorithm was proposed.Firstly,a control system model was built according to the synchronization error and tracking error.Furthermore,based on arranging the transition process,estimating the system state and error feedback,and compensating disturbance,an active disturbance rejection controller was designed by adopting the optimal control function.Finally,on-site test results showed that the cross-coupled control strategy based on the active disturbance rejection algorithm could ensure the synchronization of two actuators.The maximum speed synchronization error of the two motors was less than 16 RPM,the displacement synchronization error of the two actuators was less than 0.25 mm and approaching zero after 4 seconds,and the peak value of vibration of the blade was less than 5 mm,which satisfied the fatigue test requirement.展开更多
基金Scientific Research Fund of Institute of Engineering Mechanics,China Earthquake Administration under Grant Nos.2021EEEVL0204 and 2018A02。
文摘As an important part of nonstructural components,the seismic response of indoor water supply pipes deserves much attention.This paper presents shaking table test research on water supply pipes installed in a full-scale reinforced concrete(RC)frame structure.Different material pipes and different methods for penetrating the reinforced concrete floors are combined to evaluate the difference in seismic performance.Floor response spectra and pipe acceleration amplification factors based on test data are discussed and compared with code provisions.A seismic fragility study of displacement demand is conducted based on numerical simulation.The acceleration response and displacement response of different combinations are compared.The results show that the combination of different pipe materials and different passing-through methods can cause obvious differences in the seismic response of indoor riser pipes.
基金supported by the National Key R&D Program of China(Grant Number 2020YFB1708300)China National Postdoctoral Program for Innovative Talents(Grant Number BX20220124)+1 种基金China Postdoctoral Science Foundation(Grant Number 2022M710055)the New Cornerstone Science Foundation through the XPLORER PRIZE,the Knowledge Innovation Program of Wuhan-Shuguang,the Young Top-Notch Talent Cultivation Program of Hubei Province and the Taihu Lake Innovation Fund for Future Technology(Grant Number HUST:2023-B-7).
文摘Cellular thin-shell structures are widely applied in ultralightweight designs due to their high bearing capacity and strength-to-weight ratio.In this paper,a full-scale isogeometric topology optimization(ITO)method based on Kirchhoff-Love shells for designing cellular tshin-shell structures with excellent damage tolerance ability is proposed.This method utilizes high-order continuous nonuniform rational B-splines(NURBS)as basis functions for Kirchhoff-Love shell elements.The geometric and analysis models of thin shells are unified by isogeometric analysis(IGA)to avoid geometric approximation error and improve computational accuracy.The topological configurations of thin-shell structures are described by constructing the effective density field on the controlmesh.Local volume constraints are imposed in the proximity of each control point to obtain bone-like cellular structures.To facilitate numerical implementation,the p-norm function is used to aggregate local volume constraints into an equivalent global constraint.Several numerical examples are provided to demonstrate the effectiveness of the proposed method.After simulation and comparative analysis,the results indicate that the cellular thin-shell structures optimized by the proposed method exhibit great load-carrying behavior and high damage robustness.
基金supported by the Science and Technology Programs of Gansu Province,China(Nos.21JR1RA248,20JR10RA264)the Young Scholars Science Foundation of Lanzhou Jiaotong University,China(Nos.2020039,2020017)the Special Funds for Guiding Local Scientific and Technological Development by the Central Government,China(No.22ZY1QA005)。
文摘In order to provide more insights into the damage propagation composite wind turbine blades(blade)under cyclic fatigue loading,a stiffness degradation model for blade is proposed based on the full-scale fatigue testing of a blade.A novel non-linear fatigue damage accumulation model is proposed using the damage assessment theories of composite laminates for the first time.Then,a stiffness degradation model is established based on the correlation of fatigue damage and residual stiffness of the composite laminates.Finally,a stiffness degradation model for the blade is presented based on the full-scale fatigue testing.The scientific rationale of the proposed stiffness model of blade is verified by using full-scale fatigue test data of blade with a total length of 52.5 m.The results indicate that the proposed stiffness degradation model of the blade agrees well with the fatigue testing results of this blade.This work provides a basis for evaluating the fatigue damage and lifetime of blade under cyclic fatigue loading.
文摘Rock anchors are a common safety measure for stabilising large-scale infrastructure,such as bridge towers,retaining walls,rock slopes and windmills.There are four principal failure modes for rock anchors:(a)tensile failure of the steel anchor,(b)anchor-grout interface failure,(c)grout-rock interface failure,and(d)rock mass uplift.Field tests were performed in a limestone quarry.These tests were designed to test failure modes B and C through pullout.In the tests of failure mode B,the shear stress on the anchor-grout interface is the largest at the top of the grout column and attenuates towards the distal end for small loads.The shear stress becomes uniformly distributed when the applied load is approximately 50%of the ultimate pullout load.The anchors designed to test failure mode C were installed with an endplate and had a higher toughness than the straight bar anchors.The shear stress on the grout-rock interface is the largest at the endplate and attenuates upward before slip starts along the interface.When the ultimate pullout load is reached,and the grout column starts to slip,the shear stress is approximately constant.The bond shear strength on the anchor-grout interface was approximately 20%of the uniaxial compressive strength of the grout,and the bond strength of the grout-rock interface was around 5%for that of the grout.The grout-rock interface is likely determined by whichever is weaker,the grout or the rock.
文摘Computational fluid dynamics(CFD)provides a powerful tool for investigating complicated fluid flows.This paper aims to study the applicability of CFD in the preliminary design of linear and nonlinear fluid viscous dampers.Two fluid viscous dampers were designed based on CFD models.The first device was a linear viscous damper with straight orifices.The second was a nonlinear viscous damper containing a one-way pressure-responsive valve inside its orifices.Both dampers were detailed based on CFD simulations,and their internal fluid flows were investigated.Full-scale specimens of both dampers were manufactured and tested under dynamic loads.According to the tests results,both dampers demonstrate stable cyclic behaviors,and as expected,the nonlinear damper generally tends to dissipate more energy compared to its linear counterpart.Good compatibility was achieved between the experimentally measured damper force-velocity curves and those estimated from CFD analyses.Using a thermography camera,a rise in temperature of the dampers was measured during the tests.It was found that output force of the manufactured devices was virtually independent of temperature even during long duration loadings.Accordingly,temperature dependence can be ignored in CFD models,because a reliable temperature compensator mechanism was used(or intended to be used)by the damper manufacturer.
基金financially supported by the National Natural Science Foundation of China (Grant No.52378329)。
文摘The monopile is the most common foundation to support offshore wind turbines.In the marine environment,local scour due to combined currents and waves is a significant issue that must be considered in the design of wind turbine foundations.In this paper,a full-scale numerical model was developed and validated based on field data from Rudong,China.The scour development around monopiles was investigated,and the effects of waves and the Reynolds number Re were analyzed.Several formulas for predicting the scour depth in the literature have been evaluated.It is found that waves can accelerate scour development even if the KC number is small(0.78<KC<1.57).The formula obtained from small-scale model tests may be unsafe or wasteful when it is applied in practical design due to the scale effect.A new equation for predicting the scour depth based on the average pile Reynolds number(Rea)is proposed and validated with field data.The equilibrium scour depth predicted using the proposed equation is evaluated and compared with those from nine equations in the literature.It is demonstrated that the values predicted from the proposed equation and from the S/M(Sheppard/Melville)equation are closer to the field data.
基金financially supported by the National Key Research and Development Program of China(2022YFD1900501)National Natural Science Foundation of China(51861125103)。
文摘Driven by the concept of agricultural sustainable development,crop planting structure optimization(CPSO)has become an effective measure to reduce regional crop water demand,ensure food security,and protect the environment.However,traditional optimization of crop planting structures often ignores the impact on regional food supply–demand relations and interprovincial food trading.Therefore,using a system analysis concept and taking virtual water output as the connecting point,this study proposes a theoretical CPSO framework based on a multi-aspect and full-scale evaluation index system.To this end,a water footprint(WF)simulation module denoted as soil and water assessment tool–water footprint(SWAT-WF)is constructed to simulate the amount and components of regional crop WFs.A multi-objective spatial CPSO model with the objectives of maximizing the regional economic water productivity(EWP),minimizing the blue water dependency(BWFrate),and minimizing the grey water footprint(GWFgrey)is established to achieve an optimal planting layout.Considering various benefits,a fullscale evaluation index system based on region,province,and country scales is constructed.Through an entropy weight technique for order preference by similarity to an ideal solution(TOPSIS)comprehensive evaluation model,the optimal plan is selected from a variety of CPSO plans.The proposed framework is then verified through a case study of the upper–middle reaches of the Heihe River Basin in Gansu province,China.By combining the theory of virtual water trading with system analysis,the optimal planting structure is found.While sacrificing reasonable regional economic benefits,the optimization of the planting structure significantly improves the regional water resource benefits and ecological benefits at different scales.
基金This work was supported by the National Natural Science Foundation of China[Grant Nos.11790283,51978587,51708457]the Program of Introducing Talents of Discipline to Universities(111 Project)[Grant No.B16041].
文摘Motivated by the huge practical engineering demand for the fundamental understanding of mechanical characteristics of high-speed railway infrastructure,a fullscale multi-functional test platform for high-speed railway track–subgrade system is developed in this paper,and its main functions for investigating the mechanical performance of track–subgrade systems are elaborated with three typical experimental examples.Comprising the full-scale subgrade structure and all the five types of track structures adopted in Chinese high-speed railways,namely the CRTS I,the CRTS II and the CRTS III ballastless tracks,the double-block ballastless track and the ballasted track,the test platform is established strictly according to the construction standard of Chinese high-speed railways.Three kinds of effective loading methods are employed,including the real bogie loading,multi-point loading and the impact loading.Various types of sensors are adopted in different components of the five types of track–subgrade systems to measure the displacement,acceleration,pressure,structural strain and deformation,etc.Utilizing this test platform,both dynamic characteristics and long-term performance evolution of high-speed railway track–subgrade systems can be investigated,being able to satisfy the actual demand for large-scale operation of Chinese high-speed railways.As examples,three typical experimental studies are presented to elucidate the comprehensive functionalities of the full-scale multi-functional test platform for exploring the dynamic performance and its long-term evolution of ballastless track systems and for studying the long-term accumulative settlement of the ballasted track–subgrade system in high-speed railways.Some interesting phenomena and meaningful results are captured by the developed test platform,which provide a useful guidance for the scientific operation and maintenance of high-speed railway infrastructure.
基金Supported by the National Natural Science Foundation of China (Grant No. 50323005)the National Basic Research Program of China (Grant No. 2001CB409603)
文摘Lining materials are widely used in buildings to cover walls and ceilings. Combustible linings may produce a potential high fire hazard in buildings. Once ignited,it propagates fire and accelerates the enclosure fire growth. Two types of lining materials were studied during the tests:block board and plywood. The test was conducted in an ISO 9705 room,where linings were mounted on walls without the ceiling. By changing the heat output of the burner,the ventilation,etc.,the concentrations of CO2/CO of different lining materials were researched. The effect of test conditions on the production of CO2/CO of different lining materials was investigated,and useful experimental data were provided for the further development of numerical modeling to simulate enclosure fire growth lined with combusti-ble materials.
文摘Confining stresses serve as a pivotal determinant in shaping the behavior of grouted rock bolts.Nonetheless,prior investigations have oversimplified the three-dimensional stress state,primarily assuming hydrostatic stress conditions.Under these conditions,it is assumed that the intermediate principal stress(σ_(2))equals the minimum principal stress(σ_(3)).This assumption overlooks the potential variations in magnitudes of in situ stress conditions along all three directions near an underground opening where a rock bolt is installed.In this study,a series of push tests was meticulously conducted under triaxial conditions.These tests involved applying non-uniform confining stresses(σ_(2)≠σ_(3))to cubic specimens,aiming to unveil the previously overlooked influence of intermediate principal stresses on the strength properties of rock bolts.The results show that as the confining stresses increase from zero to higher levels,the pre-failure behavior changes from linear to nonlinear forms,resulting in an increase in initial stiffness from 2.08 kN/mm to 32.51 kN/mm.The load-displacement curves further illuminate distinct post-failure behavior at elevated levels of confining stresses,characterized by enhanced stiffness.Notably,the peak load capacity ranged from 27.9 kN to 46.5 kN as confining stresses advanced from σ_(2)=σ_(3)=0 to σ_(2)=20 MPa and σ_(3)=10 MPa.Additionally,the outcomes highlight an influence of confining stress on the lateral deformation of samples.Lower levels of confinement prompt overall dilation in lateral deformation,while higher confinements maintain a state of shrinkage.Furthermore,diverse failure modes have been identified,intricately tied to the arrangement of confining stresses.Lower confinements tend to induce a splitting mode of failure,whereas higher loads bring about a shift towards a pure interfacial shear-off and shear-crushed failure mechanism.
文摘Edge devices,due to their limited computational and storage resources,often require the use of compilers for program optimization.Therefore,ensuring the security and reliability of these compilers is of paramount importance in the emerging field of edge AI.One widely used testing method for this purpose is fuzz testing,which detects bugs by inputting random test cases into the target program.However,this process consumes significant time and resources.To improve the efficiency of compiler fuzz testing,it is common practice to utilize test case prioritization techniques.Some researchers use machine learning to predict the code coverage of test cases,aiming to maximize the test capability for the target compiler by increasing the overall predicted coverage of the test cases.Nevertheless,these methods can only forecast the code coverage of the compiler at a specific optimization level,potentially missing many optimization-related bugs.In this paper,we introduce C-CORE(short for Clustering by Code Representation),the first framework to prioritize test cases according to their code representations,which are derived directly from the source codes.This approach avoids being limited to specific compiler states and extends to a broader range of compiler bugs.Specifically,we first train a scaled pre-trained programming language model to capture as many common features as possible from the test cases generated by a fuzzer.Using this pre-trained model,we then train two downstream models:one for predicting the likelihood of triggering a bug and another for identifying code representations associated with bugs.Subsequently,we cluster the test cases according to their code representations and select the highest-scoring test case from each cluster as the high-quality test case.This reduction in redundant testing cases leads to time savings.Comprehensive evaluation results reveal that code representations are better at distinguishing test capabilities,and C-CORE significantly enhances testing efficiency.Across four datasets,C-CORE increases the average of the percentage of faults detected(APFD)value by 0.16 to 0.31 and reduces test time by over 50% in 46% of cases.When compared to the best results from approaches using predicted code coverage,C-CORE improves the APFD value by 1.1% to 12.3% and achieves an overall time-saving of 159.1%.
基金This work was supported by the National Natural Science Foundation of China(Nos.12335007,11835001,11921006,12035001 and 12205340)the State Key Laboratory of Nuclear Physics and Technology,Peking University(No.NPT2020KFY13)Gansu Natural Science Foundation(No.22JR5RA123).
文摘The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an excellent test for stateof-the-art nuclear models.The atomic nucleus is a self-organized quantum manybody system comprising specific numbers of protons Z and neutrons N.
基金Supported by Scientific Initiation Scholarship Programme(PIBIC)of the Bahia State Research Support Foundationthe Doctorate Scholarship Program of the Coordination of Improvement of Higher Education Personnel+1 种基金the Scientific Initiation Scholarship Programme(PIBIC)of the National Council for Scientific and Technological Developmentand the CNPq Research Productivity Fellowship.
文摘BACKGROUND Helicobacter pylori(H.pylori)infection has been well-established as a significant risk factor for several gastrointestinal disorders.The urea breath test(UBT)has emerged as a leading non-invasive method for detecting H.pylori.Despite numerous studies confirming its substantial accuracy,the reliability of UBT results is often compromised by inherent limitations.These findings underscore the need for a rigorous statistical synthesis to clarify and reconcile the diagnostic accuracy of the UBT for the diagnosis of H.pylori infection.AIM To determine and compare the diagnostic accuracy of 13C-UBT and 14C-UBT for H.pylori infection in adult patients with dyspepsia.METHODS We conducted an independent search of the PubMed/MEDLINE,EMBASE,and Cochrane Central databases until April 2022.Our search included diagnostic accuracy studies that evaluated at least one of the index tests(^(13)C-UBT or ^(14)C-UBT)against a reference standard.We used the QUADAS-2 tool to assess the methodo-logical quality of the studies.We utilized the bivariate random-effects model to calculate sensitivity,specificity,positive and negative test likelihood ratios(LR+and LR-),as well as the diagnostic odds ratio(DOR),and their 95%confidence intervals.We conducted subgroup analyses based on urea dosing,time after urea administration,and assessment technique.To investigate a possible threshold effect,we conducted Spearman correlation analysis,and we generated summary receiver operating characteristic(SROC)curves to assess heterogeneity.Finally,we visually inspected a funnel plot and used Egger’s test to evaluate publication bias.endorsing both as reliable diagnostic tools in clinical practice.CONCLUSION In summary,our study has demonstrated that ^(13)C-UBT has been found to outperform the ^(14)C-UBT,making it the preferred diagnostic approach.Additionally,our results emphasize the significance of carefully considering urea dosage,assessment timing,and measurement techniques for both tests to enhance diagnostic precision.Nevertheless,it is crucial for researchers and clinicians to evaluate the strengths and limitations of our findings before implementing them in practice.
文摘Screening for maternal syphilis has been an essential component of routine antenatal screening tests in most countries for many years. This is not only because of the virulence of the spirochete which causes the infection but also because of its vertical transmission rate and the potential severe adverse complications/morbidity that can result from its transmission to the fetus. Although the incidence of maternal syphilis and its fetal sequalae in low-income countries has been considerable for several years, the disease has been almost non-existent in high income countries with wide antenatal screening coverage and effective treatment programmes for Syphilis. The recent alarming increase in the incidence of maternal syphilis in high income countries has spawned a renewed public health interest in the infection, with several countries updating and strengthening public health guidance in an attempt to stem this dramatic trend. This is a short clinical update for the practising obstetrician on how to manage the antenatal patient with a positive syphilis screening test.
基金the National Natural Science Foundation of China(Grant No.61973033)Preliminary Research of Equipment(Grant No.9090102010305)for funding the experiments。
文摘The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future.
文摘Since the beginning of COVID-19 pandemics many countries were facing challenges with testing capacity recourse limitations. Throughout the waves of the pandemic countries were trying to address the existing constrains exploring solutions to increase the testing capacity with more cost-effective approaches. Pooled methodology was one of the methods which many have validated and used. It is evident that in case of pooled sample testing the sensitivity becomes lower, however the variation highly depends on the pool size as well as the incidence rate at the certain point. Armenia as well as many other countries has adopted regulations for mandatory COVID-19 PCR testing for all the travelers. Current study aimed to explore the efficiency of COVID-19 pooled PCR testing for nasopharyngeal swabs of individuals with no symptoms in a time period with good epidemiological state of the infection. Nasopharingeal swab samples from individuals were collected. The manual extraction of RNAs of samples was performed after pooling up to 5 samples. The pools with Cycle Threshold (CT) of < 37 were considered positive and were retested individually. In total 28,015 samples were grouped in 667 pools of which 57 were positive. The total number of positive samples was 65. The median difference (CT-pool–CT samples) was 2.4 (ranging from–3.0 to 8.9). The correlation of CT of pools and positive samples was positive. The correlation coefficient r = 0.84, P < 0.000, 95% CI range 0.7423 to 0.9243). The total economic saving when using pools compared to the individual testing was 72%. The minor difference between CT values of pools and samples can be explained by the dilution effect in the pool. However, the positive correlation between the values as well as the amount of cost saving demonstrate that pooling on nasopharyngeal samples for COVID-19 PCR testing can be a good method for efficient screening with significant resource saving. One of the most important advantages of the proposed method is the fact that samples are pooled prior extraction, which avoids the possibilities with misinterpretation of IC due to low yield of RNA in the extraction process.
文摘The test of Prentice [1] is a non-parametric statistical test for the two-way analysis of variance using ranks. The null distribution of this test typically is approximated using the Chi-square distribution. However, the exact null distribution deviates from the Chi-square approximation in certain cases commonly found in applications of the test, motivating adjustments to the distribution. This manuscript presents adjustments to this null distribution correcting for continuity, multivariate skewness, and multivariate kurtosis. The effects of alternative scoring methods as non-polynomial functions of rank sums are also presented as a broader application of the approximation.
文摘Introduction: Exercise stress testing (on a treadmill or ergometer bicycle) is an important test in cardiology for diagnosing myocardial ischemia. This test in Mali is still in its beginning compared to other countries in the sub-region. The lack of data in Mali prompted this study, which aimed to evaluate the indications of this activity and its diagnostic contribution to cardiology in Mali. Materials and Methods: This was a retrospective, descriptive study. The study was conducted at the “TOUCAM” medical clinic in Kati based on the analysis of stress test reports between January 2016 and August 2022. Result: During the study period, we documented 73 patients who underwent exercise testing on a bicycle ergometer for suspected coronary heart disease. The mean age of our patients was 47.5 ± 13.8 years (14 and 79 years). Males accounted for the majority (78.1%). The sex ratio is 3.5. More than half of our patients were overweight or obese (77.1%). Hypertension and diabetes affected 52.1% and 25.8% of patients, respectively. 20.8% of patients had coronary artery disease. renin-angiotensin-aldosterone system blockers (56.8%) and beta-blockers (51.3%). The main indications were chest pain (63.0%) and ischemia detection (15.1%). A modified STEEP protocol was used. The majority of our patients (71.2%) achieved at least 85% of their maximum theoretical heart rate. The main reason for the termination of the study was fatigue (57.3%). The average duration was 11.3 ± 4.2 minutes. 24.7% thought the stress tests were positive and 17.8% thought they were controversial. Conclusion: This study demonstrates the importance of stress testing in the diagnosis and treatment of ischemic heart disease, especially in settings where we have very limited access to coronary angiography.
基金the National Key R&D Program of China,Grant No.2018YFB1501203Meanwhile,this research was funded by the Natural Science Foundation of Shandong,Grant No.ZR2019MEE076And the work in this paper has partly received funding from the National Key R&D Program of Shandong,Grant No.2019GGX104001.
文摘A new dual-actuator fatigue loading system of wind turbine blades was designed.Compared with the traditional pendulum loading mode,the masses in this system only moved linearly along the loading direction to increase the exciting force.However,the two actuators and the blade constituted a complicated non-linear energy transferring system,which led to the non-synchronization of actuators.On-site test results showed that the virtual spindle synchronous strategy commonly used in synchronous control was undesirable and caused the instability of the blade’s amplitude eventually.A cross-coupled control strategy based on the active disturbance rejection algorithm was proposed.Firstly,a control system model was built according to the synchronization error and tracking error.Furthermore,based on arranging the transition process,estimating the system state and error feedback,and compensating disturbance,an active disturbance rejection controller was designed by adopting the optimal control function.Finally,on-site test results showed that the cross-coupled control strategy based on the active disturbance rejection algorithm could ensure the synchronization of two actuators.The maximum speed synchronization error of the two motors was less than 16 RPM,the displacement synchronization error of the two actuators was less than 0.25 mm and approaching zero after 4 seconds,and the peak value of vibration of the blade was less than 5 mm,which satisfied the fatigue test requirement.