In this article,we employ a fully-resolved numerical simulation method(the fictitious domain method)to investigate the effects of large neutrally-buoyant particles on the turbulent flow in a pipe at low Reynolds num...In this article,we employ a fully-resolved numerical simulation method(the fictitious domain method)to investigate the effects of large neutrally-buoyant particles on the turbulent flow in a pipe at low Reynolds number and non-dilute regimes.The tube Reynolds number is fixed to be 4 900,the particle-pipe diameter ratio is 0.1,and the particle volume fraction ranges from 0.33%to 10%.Our results indicate that the presence of large particles decreases the maximum root-of-mean-square(rms)of the streamwise velocity fluctuation near the wall by weakening the intensity of large-scale streamwise vortices,although in the region very close to the wall the particles increase the rms of streamwise velocity fluctuation.On the other hand,the particles induce small-scale vortices in the near-wall region,resulting in the enhancement of the rms of radial and circumferential velocity fluctuations there.展开更多
Fully resolved numerical simulations of a micron-sized spherical particle residing on a surface with large-scale roughness are performed by using the Lattice-Boltzmann method.The aim is to investigate the influence of...Fully resolved numerical simulations of a micron-sized spherical particle residing on a surface with large-scale roughness are performed by using the Lattice-Boltzmann method.The aim is to investigate the influence of surface roughness on the detachment of fine drug particles from larger carrier particles for transporting fine drug particles in a DPI(dry powder inhaler).Often the carrier surface is modified by mechanical treatments for modifying the surface roughness in order to reduce the adhesion force of drug particles.Therefore,drug particle removal from the carrier surface is equivalent to the detachment of a sphere from a rough plane surface.Here a sphere with a diameter of 5μm at a particle Reynolds number of 1.0,3.5 and 10 are considered.The surface roughness is described as regularly spaced semi-cylindrical asperities(with the axes oriented normal to the flow direction)on a smooth surface.The influence of asperity distance and size ratio(i.e.the radius of the semi-cylinder to the particle radius,Rc/Rd)on particle adhesion and detachment are studied.The asperity distance is varied in the range 1.2<L/Rd<2 and the semi-cylinder radius between 0.5<Rc/Rd<0.75.The required particle resolution and domain size are appropriately selected based on numerical studies,and a parametric analysis is performed to investigate the relationship between the contact distance(i.e.half the distance between the particle contact points on two neighbouring semi-cylinders),the asperity distance,the size ratio,and the height of the particle centroid from the plane wall.The drag,lift and torque acting on the spherical particle are measured for different particle Reynolds numbers,asperity distances and sizes or diameters.The detachment of particles from rough surfaces can occur through lift-off,sliding and rolling,and the corresponding detachment models are constructed for the case of rough surfaces.These studies will be the basis for developing Lagrangian detachment models that eventually should allow the optimisation of dry powder inhaler performance through computational fluid dynamics.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11072217, 10872181)the Fundamental Research Funds for the Central Universities (Grant Nos. 2009QNA4036, 2010QNA4015)
文摘In this article,we employ a fully-resolved numerical simulation method(the fictitious domain method)to investigate the effects of large neutrally-buoyant particles on the turbulent flow in a pipe at low Reynolds number and non-dilute regimes.The tube Reynolds number is fixed to be 4 900,the particle-pipe diameter ratio is 0.1,and the particle volume fraction ranges from 0.33%to 10%.Our results indicate that the presence of large particles decreases the maximum root-of-mean-square(rms)of the streamwise velocity fluctuation near the wall by weakening the intensity of large-scale streamwise vortices,although in the region very close to the wall the particles increase the rms of streamwise velocity fluctuation.On the other hand,the particles induce small-scale vortices in the near-wall region,resulting in the enhancement of the rms of radial and circumferential velocity fluctuations there.
基金supported by the Chinese Fundamental Research Funds for the Central Universities of the project No.2020kfyXJJS065.
文摘Fully resolved numerical simulations of a micron-sized spherical particle residing on a surface with large-scale roughness are performed by using the Lattice-Boltzmann method.The aim is to investigate the influence of surface roughness on the detachment of fine drug particles from larger carrier particles for transporting fine drug particles in a DPI(dry powder inhaler).Often the carrier surface is modified by mechanical treatments for modifying the surface roughness in order to reduce the adhesion force of drug particles.Therefore,drug particle removal from the carrier surface is equivalent to the detachment of a sphere from a rough plane surface.Here a sphere with a diameter of 5μm at a particle Reynolds number of 1.0,3.5 and 10 are considered.The surface roughness is described as regularly spaced semi-cylindrical asperities(with the axes oriented normal to the flow direction)on a smooth surface.The influence of asperity distance and size ratio(i.e.the radius of the semi-cylinder to the particle radius,Rc/Rd)on particle adhesion and detachment are studied.The asperity distance is varied in the range 1.2<L/Rd<2 and the semi-cylinder radius between 0.5<Rc/Rd<0.75.The required particle resolution and domain size are appropriately selected based on numerical studies,and a parametric analysis is performed to investigate the relationship between the contact distance(i.e.half the distance between the particle contact points on two neighbouring semi-cylinders),the asperity distance,the size ratio,and the height of the particle centroid from the plane wall.The drag,lift and torque acting on the spherical particle are measured for different particle Reynolds numbers,asperity distances and sizes or diameters.The detachment of particles from rough surfaces can occur through lift-off,sliding and rolling,and the corresponding detachment models are constructed for the case of rough surfaces.These studies will be the basis for developing Lagrangian detachment models that eventually should allow the optimisation of dry powder inhaler performance through computational fluid dynamics.