Pituitary adenoma may be calssifded in light of the hormones produced. 225 surgical specimens were labeled with anti-sear of GH, PRL. ACTH, TSH, FSH and LH by immunohistochemical technique (ABC method). Data indicated...Pituitary adenoma may be calssifded in light of the hormones produced. 225 surgical specimens were labeled with anti-sear of GH, PRL. ACTH, TSH, FSH and LH by immunohistochemical technique (ABC method). Data indicated that 100 out of 225 cases (44.5%) were monohormonal adenomas, including 24 GH, 39 PRL, 1 FSH and 9 LH, 77 (34.2%) were multi-hormonal adenomas, including 28 positive for 2 hormones, 30 positive for 3 hormones, 19 positive for 4 or more different hormones, and the remaining 48 (21.3%) were nonfunctional adenomas. In comparison with Kovacs series, factors which might participate in the mechanism of developing monohormonal or multi-hormonal adenomas are discussed.展开更多
文摘Pituitary adenoma may be calssifded in light of the hormones produced. 225 surgical specimens were labeled with anti-sear of GH, PRL. ACTH, TSH, FSH and LH by immunohistochemical technique (ABC method). Data indicated that 100 out of 225 cases (44.5%) were monohormonal adenomas, including 24 GH, 39 PRL, 1 FSH and 9 LH, 77 (34.2%) were multi-hormonal adenomas, including 28 positive for 2 hormones, 30 positive for 3 hormones, 19 positive for 4 or more different hormones, and the remaining 48 (21.3%) were nonfunctional adenomas. In comparison with Kovacs series, factors which might participate in the mechanism of developing monohormonal or multi-hormonal adenomas are discussed.
