期刊文献+
共找到448篇文章
< 1 2 23 >
每页显示 20 50 100
Cortical activity in patients with high-functioning ischemic stroke during the Purdue Pegboard Test:insights into bimanual coordinated fine motor skills with functional near-infrared spectroscopy
1
作者 Siyun Chen Mengchai Mao +4 位作者 Guangyue Zhu Yufeng Chen Yuqi Qiu Bin Ye Dongsheng Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第5期1098-1104,共7页
After stroke,even high-functioning individuals may experience compromised bimanual coordination and fine motor dexterity,leading to reduced functional independence.Bilateral arm training has been proposed as a promisi... After stroke,even high-functioning individuals may experience compromised bimanual coordination and fine motor dexterity,leading to reduced functional independence.Bilateral arm training has been proposed as a promising intervention to address these deficits.However,the neural basis of the impairment of functional fine motor skills and their relationship to bimanual coordination performance in stroke patients remains unclear,limiting the development of more targeted interventions.To address this gap,our study employed functional near-infrared spectroscopy to investigate cortical responses in patients after stroke as they perform functional tasks that engage fine motor control and coordination.Twenty-four high-functioning patients with ischemic stroke(7 women,17 men;mean age 64.75±10.84 years)participated in this cross-sectional observational study and completed four subtasks from the Purdue Pegboard Test,which measures unimanual and bimanual finger and hand dexterity.We found significant bilateral activation of the sensorimotor cortices during all Purdue Pegboard Test subtasks,with bimanual tasks inducing higher cortical activation than the assembly subtask.Importantly,patients with better bimanual coordination exhibited lower cortical activation during the other three Purdue Pegboard Test subtasks.Notably,the observed neural response patterns varied depending on the specific subtask.In the unaffected hand task,the differences were primarily observed in the ipsilesional hemisphere.In contrast,the bilateral sensorimotor cortices and the contralesional hemisphere played a more prominent role in the bimanual task and assembly task,respectively.While significant correlations were found between cortical activation and unimanual tasks,no significant correlations were observed with bimanual tasks.This study provides insights into the neural basis of bimanual coordination and fine motor skills in high-functioning patients after stroke,highlighting task-dependent neural responses.The findings also suggest that patients who exhibit better bimanual performance demonstrate more efficient cortical activation.Therefore,incorporating bilateral arm training in post-stroke rehabilitation is important for better outcomes.The combination of functional near-infrared spectroscopy with functional motor paradigms is valuable for assessing skills and developing targeted interventions in stroke rehabilitation. 展开更多
关键词 bilateral arm training bimanual coordination cortical activity fine motor dexterity functional near-infrared spectroscopy(fnirs) high-functioning Purdue Pegboard Test stroke
下载PDF
Correlation between LIFG and Autonomic Activation during Stressful Tasks:A Functional Near-infrared Spectroscopy (fNIRS) Study 被引量:1
2
作者 史洁 酒谷薰 +2 位作者 冈本雅子 山口由衣 左焕琮 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2014年第5期663-671,共9页
It remains unclear whether language tasks in one's first (L1) or second (L2) language can cause stress responses and whether frontal, autonomic and behavioral responses to stressful tasks are correlated. In this ... It remains unclear whether language tasks in one's first (L1) or second (L2) language can cause stress responses and whether frontal, autonomic and behavioral responses to stressful tasks are correlated. In this study, we studied 22 Chinese subjects whose L2 was English and measured the cerebral blood oxygenation in their frontal lobe by using functional near-infrared spectroscopy (fNIRS) as par- ticipants engaged in a mental arithmetic task (MAT) and verbal fluency tasks (VFTs) in L1 (Chinese) and L2 (English). To examine the activated cortical areas, we estimated the channel location based on Montreal Neurological Institute (MNI) standard brain space by using a-probabilistic estimation method. We evaluated heart rate (HR) changes to analyze autonomic nervous system (ANS) functioning. We found that the MAT and VFTs induced greater increases in HR than did the control (Ctrl) task. Further- more, subjects developed greater increases in HR in the MAT and VFTt~ than they did in the VFTL1. Compared with the Ctrl task, the MAT and both VFTLland VFTL2 produced robust and widespread bi- lateral activation of the frontal cortex. Interestingly, partial correlation analysis indicated that the activity in the left inferior frontal gyrus (LIFG) [Brodmarm's area (BA) 47] was consistently correlated with the increases in HR across the three tasks (MAT, VFTL2, and VFTL1), after controlling for the performance data. The present results suggested that a VFT in L2 may be more stressful than in L1. The LIFG may affect the activation of the sympathetic system induced by stressful tasks, includin~ MATs and VFTs. 展开更多
关键词 functional near-infrared spectroscopy mental arithmetic task verbal fluency task auto-nomic nervous system inferior frontal gyrus
下载PDF
定向运动练习对大学生空间定向能力的影响:来自行为学和fNIRS的证据
3
作者 殷春宇 史利 +1 位作者 张文 刘阳 《体育学刊》 CAS CSSCI 北大核心 2024年第5期135-142,共8页
探讨定向运动练习对大学生空间定向能力的影响及其脑机制,为提升人的空间认知能力提供新途径和科学依据。以48名大一学生为研究对象,随机分为实验组和对照组,对实验组进行8周定向运动练习干预,采用功能性近红外光谱成像系统(fNIRS)记录... 探讨定向运动练习对大学生空间定向能力的影响及其脑机制,为提升人的空间认知能力提供新途径和科学依据。以48名大一学生为研究对象,随机分为实验组和对照组,对实验组进行8周定向运动练习干预,采用功能性近红外光谱成像系统(fNIRS)记录被试者大脑氧合血红蛋白(Oxy-Hb)浓度变化,分析被试者干预前后空间定向认知任务的行为表现及神经机制。结果表明:(1)定向运动练习显著提升练习者空间定向认知任务的正确率且显著优于对照组。(2)在空间定向任务中,实验组左侧腹外侧前额叶(L-VLPFC)和左侧背外侧前额叶(L-DLPFC)的Oxy-Hb激活显著降低且低于对照组。(3)实验组腹外侧前额叶(VLPFC)的Oxy-Hb浓度与正确率显著相关。研究认为,定向运动练习可以有效改善练习者的空间定向认知能力,且空间定向能力的改善效益与大脑前额叶皮层激活程度有关。定向运动练习改善练习者空间定向能力的脑机制可能是通过改变练习者的空间认知加工模式,从而促进其脑神经活动的优化。 展开更多
关键词 定向运动 认知功能 空间定向 功能性近红外光谱成像系统
下载PDF
幼儿体质健康水平与工作记忆加工的差异特征:来自fNIRS的证据
4
作者 郑权良 李红娟 +3 位作者 宁科 史兵 武陈 郭玉江 《首都体育学院学报》 CSSCI 北大核心 2024年第3期267-278,共12页
目的:探讨幼儿体质健康发展水平与工作记忆加工的大脑神经关联,为幼儿体质健康促进与认知发展提供依据。方法:选取98名4~6岁学龄前儿童,按照《国民体质测定标准手册(幼儿部分)》的内容评估幼儿体质健康发展水平,采用功能性近红外光谱脑... 目的:探讨幼儿体质健康发展水平与工作记忆加工的大脑神经关联,为幼儿体质健康促进与认知发展提供依据。方法:选取98名4~6岁学龄前儿童,按照《国民体质测定标准手册(幼儿部分)》的内容评估幼儿体质健康发展水平,采用功能性近红外光谱脑成像(fNIRS)技术,监测幼儿执行工作记忆任务时的大脑前额叶皮层血氧动力学信号,采用4(体质健康,分为优秀、良好、合格、不合格)×2(记忆难度,分为低记忆难度、高记忆难度)的混合实验设计探讨幼儿体质健康水平与大脑工作记忆时的行为学和前额叶氧合血红蛋白浓度差异。结果:1)在低记忆难度条件下,体质健康优秀组的氧合血红蛋白浓度在右侧背外侧前额叶皮层(R-DLPFC)显著大于良好组,在R-DLPFC、右侧三角部布罗卡氏区(R-PTBA)、右侧额极区(R-FPA)及左侧背外侧前额叶皮层(L-DLPFC)显著大于合格组,在L-DLPFC显著大于不合格组;2)在高记忆难度条件下,优秀组的氧合血红蛋白浓度在R-DLPFC显著大于良好组,在R-DLPFC、R-PTBA、R-FPA及L-DLPFC显著大于合格组和不合格组;良好组的氧合血红蛋白浓度在L-DLPFC和R-PTBA显著大于合格组,在R-DLPFC、R-PTBA、R-FPA及L-DLPFC显著大于不合格组,合格组的氧合血红蛋白浓度在R-DLPFC、R-FPA及L-DLPFC的氧合血红蛋白浓度显著大于不合格组;3)优秀组和良好组在高记忆难度条件下的R-DLPFC、R-PTBA、R-FPA及L-DLPFC显著大于低记忆难度条件下;4)合格组在高记忆难度条件下的R-FPA和L-DLPFC的氧合血红蛋白浓度显著大于低记忆难度条件下;5)不合格组在高记忆难度条件下的R-PTBA的氧合血红蛋白浓度显著大于低记忆难度条件下。结论:幼儿的体质健康发展水平与工作记忆存在密切关联,表现为体质健康发展水平越高,大脑在执行工作记忆任务时的前额叶相关皮层激活程度越高。 展开更多
关键词 体质健康 工作记忆 幼儿 功能性近红外光谱脑成像 差异特征 身体活动
下载PDF
EEG-fNIRS技术在神经精神疾病研究中的应用进展
5
作者 高晨洋 吴凯 +5 位作者 李文豪 李懿 蒋知乐 汪煜新 陈文睿 周静 《中国医学物理学杂志》 CSCD 2024年第3期348-355,共8页
通过脑电图(EEG)、功能近红外光谱成像(fNIRS)、功能磁共振成像对神经精神疾病已经开展广泛的研究与应用。近年来随着技术的不断发展,EEG与fNIRS的同步采集设备被开发且逐步应用于神经精神疾病的研究中。本文首先对EEG-fNIRS设备的同步... 通过脑电图(EEG)、功能近红外光谱成像(fNIRS)、功能磁共振成像对神经精神疾病已经开展广泛的研究与应用。近年来随着技术的不断发展,EEG与fNIRS的同步采集设备被开发且逐步应用于神经精神疾病的研究中。本文首先对EEG-fNIRS设备的同步检测与数据分析技术进行简要概述,总结脑卒中、癫痫以及其他神经精神疾病研究中EEG-fNIRS的分析方法与最新发现,并探讨研究的发展方向。 展开更多
关键词 脑卒中 癫痫 神经精神疾病 脑电图 功能近红外光谱成像 综述
下载PDF
基于fNIRS观察针药并用治疗首发轻中度抑郁障碍的脑效应
6
作者 代轶楠 彭力 +1 位作者 穆敬平 郑苏 《上海针灸杂志》 CSCD 2024年第11期1222-1228,共7页
目的观察针药并用治疗首发轻中度抑郁症的抑郁症状及脑神经活动的影响。方法将60例首发轻中度抑郁症患者随机分为观察组和对照组,每组30例。观察组予以针刺联合艾司西酞普兰治疗,对照组予以假针刺联合艾司西酞普兰治疗。比较两组治疗前... 目的观察针药并用治疗首发轻中度抑郁症的抑郁症状及脑神经活动的影响。方法将60例首发轻中度抑郁症患者随机分为观察组和对照组,每组30例。观察组予以针刺联合艾司西酞普兰治疗,对照组予以假针刺联合艾司西酞普兰治疗。比较两组治疗前后HAMD评分变化,并采用功能性近红外光谱技术(functional near-infrared spectroscopy,fNIRS)比较两组任务态下各脑区激活程度(β值)。结果两组治疗后HAMD评分均较治疗前降低(P<0.05),且观察组均低于对照组(P<0.05)。两组治疗后双侧额极前额叶区的β值均较治疗前升高(P<0.05);观察组治疗后双侧额极前额叶、左背外侧前额叶β值高于对照组(P<0.05)。两组治疗后右侧额叶β值与HAMD评分呈负相关(P<0.05)。结论针刺联合艾司西酞普兰可改善首发抑郁患者抑郁症状,其机制可能与激活双侧额极前额叶、左侧背外侧前额叶有关。 展开更多
关键词 针刺疗法 针药并用 功能性近红外光谱技术 抑郁症 脑效应
下载PDF
基于卷积自编码的fNIRS信号运动校正算法研究
7
作者 李永康 李茜 +2 位作者 王琦雯 徐琪 李晓欧 《红外技术》 CSCD 北大核心 2024年第8期923-932,共10页
功能性近红外光谱技术(functional near-infrared spectroscopy,fNIRS)作为一种高时间分辨率、成本低廉、便携性高的脑成像系统,近年来深受脑神经科学等研究领域的关注。但fNIRS信号中的运动伪迹会干扰后期数据分析的结果,且现有的一些... 功能性近红外光谱技术(functional near-infrared spectroscopy,fNIRS)作为一种高时间分辨率、成本低廉、便携性高的脑成像系统,近年来深受脑神经科学等研究领域的关注。但fNIRS信号中的运动伪迹会干扰后期数据分析的结果,且现有的一些算法去噪效果较为单一。因此,本文提出了一种基于多层卷积自编码的fNIRS信号运动伪迹校正算法——MCAN算法,并使用该算法对fNIRS信号中的3种运动伪迹进行校正;然后用仿真数据和实验数据对所提算法的性能进行验证,将其与现有的几种常用算法进行对比,结果表明:MCAN算法在剩余运动伪迹数量、均方误差、信噪比、皮尔逊相关系数的平方、峰峰误差几种指标上表现良好,说明所提算法可作为一种全新的fNIRS信号预处理算法。 展开更多
关键词 功能性近红外光谱 卷积自编码 卷积神经网络 预处理 运动伪迹
下载PDF
基于fNIRS对女性不同膀胱状态下盆底肌收缩任务的前额叶激活情况
8
作者 徐正娴 潘伟婷 +4 位作者 于灿灿 周星辰 石娇 王敏 陈尚杰 《新医学》 CAS 2024年第4期280-286,共7页
目的为探讨前额叶在人体控尿功能中发挥的作用提供神经影像学依据。方法利用近红外脑功能成像技术(fNIRS)收集20名健康成年女性志愿者膀胱充盈和空虚状态下盆底肌收缩时大脑前额皮层的血流动力学数据,并对数据进行相应的处理,通过分析... 目的为探讨前额叶在人体控尿功能中发挥的作用提供神经影像学依据。方法利用近红外脑功能成像技术(fNIRS)收集20名健康成年女性志愿者膀胱充盈和空虚状态下盆底肌收缩时大脑前额皮层的血流动力学数据,并对数据进行相应的处理,通过分析各个通道所提取的氧合血红蛋白浓度的相对变化量所对应的Beta值,对比前额叶不同脑区间激活情况差异。结果膀胱充盈状态下前额皮层共有30个通道激活,膀胱空虚状态下前额皮层共有8个通道激活(P均<0.05),其中共同激活通道有7个;相较于空虚状态,膀胱充盈时的前额叶激活更明显,且以右侧脑区激活为主,差异主要体现在右侧背外侧前额叶和额极(P均<0.05)。结论盆底肌收缩运动可以使大脑前额皮层被激活。当膀胱处于充盈状态时大脑前额皮层可能会通过神经反射活动感知膀胱的压力变化,从而参与调控盆底肌的自主舒缩运动,实现其在人体控尿功能中的作用,其中右侧背外侧前额叶脑区在此过程中发挥的作用可能更为明显。 展开更多
关键词 近红外脑功能成像技术 前额叶 盆底肌收缩 膀胱状态 女性
下载PDF
基于fNIRS的主动、被动与想象屈肘运动脑激活的特点及比较
9
作者 喻多多 魏聪惠 罗军 《南昌大学学报(医学版)》 2024年第3期46-51,共6页
目的 利用功能性近红外光谱成像(functional near-infrared spectroscopy, fNIRS)技术探究健康成年人主动屈肘、被动屈肘和想象屈肘运动脑激活的特点。方法 选取30名健康大学生为被试者,男女各15例,年龄(21.22±1.42)岁,选择右手主... 目的 利用功能性近红外光谱成像(functional near-infrared spectroscopy, fNIRS)技术探究健康成年人主动屈肘、被动屈肘和想象屈肘运动脑激活的特点。方法 选取30名健康大学生为被试者,男女各15例,年龄(21.22±1.42)岁,选择右手主动、被动和想象屈肘任务作为刺激模式,采用近红外光谱脑功能成像系统实时采集被试者3种不同运动模式下脑功能区氧合血红蛋白(Oxyhemoglobin, HbO2)水平作为脑激活的特征值,并以静息态(resting state, RS)的HbO2水平为基线值,比较3种运动模式下脑激活的特点。结果 非参数检验结果表明,不同运动模式下,右侧初级运动皮层(H=13.309,P=0.004),右侧前额叶前部皮层(H=20.30,P<0.001),右侧背外侧前额叶皮层(H=12.194,P=0.007),左侧初级体感皮层(H=12.642,P=0.005),左侧初级运动皮层(H=20.03,P<0.001),左侧前额叶前部皮层(H=18.187,P<0.001),左侧背外侧前额叶皮层(H=13.379,P=0.004)的HbO2水平比较差异有统计学意义;而其右侧初级体感皮层(H=4.284,P=0.232),右侧前运动区和辅助运动皮层(H=4.201,P=0.241),左侧前运动区和辅助运动皮层(H=8.793,P=0.052)HbO2水平比较差异无统计学意义。结论 不同运动模式下存在特定的脑功能区激活,其激活程度既有相似性又有差异性,主动运动和被动运动任务下的脑激活区最类似。 展开更多
关键词 功能性近红外光谱成像技术 主动运动 被动运动 想象运动 氧合血红蛋白 脑功能区 脑激活
下载PDF
用于大脑疲劳检测的fNIRS系统设计
10
作者 沈无双 沈慧娟 +3 位作者 苏彤 王浩 张学典 马佩 《光学仪器》 2024年第4期46-55,共10页
大脑疲劳的症状体现在认知能力的下降,认知功能主要由前额叶皮层(PFC)调控。功能性近红外脑成像技术(fNIRS)能够测量一段时间内的大脑血氧浓度变化,从而间接反映大脑皮层的激活程度。设计了一款具有10通道且可覆盖前额叶区域的可穿戴fN... 大脑疲劳的症状体现在认知能力的下降,认知功能主要由前额叶皮层(PFC)调控。功能性近红外脑成像技术(fNIRS)能够测量一段时间内的大脑血氧浓度变化,从而间接反映大脑皮层的激活程度。设计了一款具有10通道且可覆盖前额叶区域的可穿戴fNIRS头带,并使用该头带对受试者大脑进行检测,观察受试者是否进入疲劳状态。设备采用780 nm和850 nm的激光二极管和光电二极管作为光源和光电探测器,光源采用频分复用的调制方法来区分两种波长以及屏蔽环境光的干扰,并且采用时分复用的方法驱动光源以获得较高的探测效率。fNIRS头带制作完成后将其应用于间隔认知测试,结果发现氧合血红蛋白(HbO)和脱氧血红蛋白(Hb)的浓度均存在间隔性变化,证实了fNIRS头带的可行性。随后招募受试者参与模拟驾驶实验,并在模拟前后测量认知能力。fNIRS成像结果均能观察到在实验后期背外侧前额叶(DLPFC)皮层HbO浓度的下降,且认知任务结果显示认知能力下降,表明实验后期受试者大脑开始疲劳,由此验证了f NIRS头带检测疲劳的可行性。 展开更多
关键词 功能性近红外脑成像技术(fnirs) 前额叶 血氧浓度 疲劳检测
下载PDF
弹力带抗阻运动对高龄老年人工作记忆的影响——来自fNIRS的证据
11
作者 蔡治东 江婉婷 王兴 《上海体育大学学报》 CSSCI 北大核心 2024年第3期65-74,共10页
目的观察长期弹力带运动改善高龄老年人工作记忆的效果,采用近红外光谱技术探究可能的脑机制。方法将60名高龄老年人随机分为弹力带组与对照组,弹力带组接受16周、每周3次、每次40 min的弹力带干预,对照组保持原有生活状态;采集实验前... 目的观察长期弹力带运动改善高龄老年人工作记忆的效果,采用近红外光谱技术探究可能的脑机制。方法将60名高龄老年人随机分为弹力带组与对照组,弹力带组接受16周、每周3次、每次40 min的弹力带干预,对照组保持原有生活状态;采集实验前后受试者完成工作记忆任务期间的前额叶血流动力学指标。结果反应时的时间×组别交互效应具有统计学意义(P<0.001);正确率的时间×记忆负荷交互效应具有统计学意义(P=0.003);正确反应率的时间×组别交互效应具有统计学意义(P<0.001);氧合血红蛋白结果显示,9条通道组别×时间×记忆负荷交互效应均具有统计学意义(P<0.002)。结论规律性中低强度弹力带抗阻运动能改善高龄老年人的工作记忆表现;在低记忆负荷时前额叶激活不明显,中、高记忆负荷时双侧腹外侧前额叶、左背外侧前额叶、左额极区显著激活,这种前额叶激活优化模式可能是弹力带抗阻运动改善工作记忆的脑机制。 展开更多
关键词 高龄老年人 执行功能 功能性近红外光谱 抗阻运动 弹力带 脑激活
下载PDF
基于fNIRS和神经反馈的记忆认知训练研究
12
作者 李鑫鑫 卜令国 《中国医疗器械杂志》 2024年第2期132-137,共6页
该研究使用功能性近红外光谱技术和神经反馈机制开发了记忆任务训练系统,并对被试的脑电信号进行采集和分析。结果显示,参与神经反馈任务的被试在前额叶部右半脑区具有更高的相关性脑网络节点度和平均集群系数,中介中心度的分散程度相... 该研究使用功能性近红外光谱技术和神经反馈机制开发了记忆任务训练系统,并对被试的脑电信号进行采集和分析。结果显示,参与神经反馈任务的被试在前额叶部右半脑区具有更高的相关性脑网络节点度和平均集群系数,中介中心度的分散程度相对降低。此外,被试的前额叶部左半脑区在神经反馈任务中的核心地位上升。通过通道网络模型和支持向量机模型对脑数据进行分类,结果表明两个模型在任务态和静息态的分类准确率高于反馈任务和对照任务,且通道网络模型的分类准确率更高。该研究结果表明神经反馈任务的被试具有明显的脑数据特征,并且这些特征能够被有效识别。 展开更多
关键词 功能性近红外光谱技术 神经反馈 脑网络 通道网络模型
下载PDF
基于改进型生成式对抗网络的EEG-fNIRS多模态信号数据增广研究
13
作者 王鹏举 李明爱 《北京生物医学工程》 2024年第3期250-258,共9页
目的基于深度学习的脑电图-功能性近红外光谱技术(electroencephalogram-functional near-infrared spectroscopy,EEG-fNIRS)多模态脑机接口在康复工程中具有广泛的应用前景,但存在数据量不足的问题。为此,本文提出一种基于改进条件生... 目的基于深度学习的脑电图-功能性近红外光谱技术(electroencephalogram-functional near-infrared spectroscopy,EEG-fNIRS)多模态脑机接口在康复工程中具有广泛的应用前景,但存在数据量不足的问题。为此,本文提出一种基于改进条件生成式对抗网络(conditional generative adversarial network,CGAN)的EEG-fNIRS多模态信号数据增广方法,以解决EEG-fNIRS多模态脑机接口与深度学习结合时面临的数据量匮乏的问题。方法首先,对EEG和fNIRS数据进行滤波、归一化和下采样等预处理。然后,针对EEG的非平稳特点,在CGAN生成器和判别器中增加自注意力机制,获得EEG数据增广模型CGAN_(E),加强捕捉和学习时变关键信息的能力。同时,针对fNIRS采样率低、信息量不充分问题,在CGAN生成器和判别器中增加上采样卷积层,获得fNIRS数据增广模型CGAN_(f),加强模型的信息挖掘能力,并将CGAN_(E)和CGAN_(f)的条件信息设置为类标签;进而,利用CGAN_(E)和CGAN_(f)对每导EEG和fNIRS分别进行增广,并将多导EEG扩增数据和多导fNIRS[包括氧合血红蛋白浓度(oxyhemoglobin concentration,HbO)和脱氧血红蛋白浓度(deoxyhemoglobin concentration,HbR)两种]扩增数据串接融合,获得EEG-fNIRS多模态增广数据。最后,对公开的EEG-fNIRS多模态信号数据集TU-Berlin-A前6名受试者数据进行增广实验,并设计一维卷积神经网络分类器评估增广数据的质量。结果基于EEG-fNIRS多模态信号公开数据集TU-Berlin-A前6名受试者的左右手运动想象数据进行实验研究表明,当数据扩增5倍时,本文方法取得94.81%的平均分类准确率。结论CGAN_(E)和CGAN_(f)能够生成接近真实数据分布的EEG和fNIRS信号,验证了对CGAN改进和本文所提EEG-fNIRS多模态数据增广方法的有效性。 展开更多
关键词 脑电图 功能性近红外光成像技术 多模态信号 条件生成式对抗网络 数据增广
下载PDF
Acupuncture enhances brain function in patients with mild cognitive impairment: evidence from a functional-near infrared spectroscopy study 被引量:11
14
作者 M.N.Afzal Khan Usman Ghafoor +1 位作者 Ho-Ryong Yoo Keum-Shik Hong 《Neural Regeneration Research》 SCIE CAS CSCD 2022年第8期1850-1856,共7页
Mild cognitive impairment(MCI)is a precursor to Alzheimer’s disease.It is imperative to develop a proper treatment for this neurological disease in the aging society.This observational study investigated the effects ... Mild cognitive impairment(MCI)is a precursor to Alzheimer’s disease.It is imperative to develop a proper treatment for this neurological disease in the aging society.This observational study investigated the effects of acupuncture therapy on MCI patients.Eleven healthy individuals and eleven MCI patients were recruited for this study.Oxy-and deoxy-hemoglobin signals in the prefrontal cortex during working-memory tasks were monitored using functional near-infrared spectroscopy.Before acupuncture treatment,working-memory experiments were conducted for healthy control(HC)and MCI groups(MCI-0),followed by 24 sessions of acupuncture for the MCI group.The acupuncture sessions were initially carried out for 6 weeks(two sessions per week),after which experiments were performed again on the MCI group(MCI-1).This was followed by another set of acupuncture sessions that also lasted for 6 weeks,after which the experiments were repeated on the MCI group(MCI-2).Statistical analyses of the signals and classifications based on activation maps as well as temporal features were performed.The highest classification accuracies obtained using binary connectivity maps were 85.7%HC vs.MCI-0,69.5%HC vs.MCI-1,and 61.69%HC vs.MCI-2.The classification accuracies using the temporal features mean from 5 seconds to 28 seconds and maximum(i.e,max(5:28 seconds))values were 60.6%HC vs.MCI-0,56.9%HC vs.MCI-1,and 56.4%HC vs.MCI-2.The results reveal that there was a change in the temporal characteristics of the hemodynamic response of MCI patients due to acupuncture.This was reflected by a reduction in the classification accuracy after the therapy,indicating that the patients’brain responses improved and became comparable to those of healthy subjects.A similar trend was reflected in the classification using the image feature.These results indicate that acupuncture can be used for the treatment of MCI patients. 展开更多
关键词 ACUPUNCTURE Alzheimer’s disease COGNITION convolutional neural network functional connectivity functional-near infrared spectroscopy hemodynamic response linear discriminant analysis mild cognitive impairment
下载PDF
DETECTING BILATERAL FUNCTIONAL CONNECTIVITY IN THE PREFRONTAL CORTEX DURING A STROOP TASK BY NEAR-INFRARED SPECTROSCOPY 被引量:1
15
作者 LEI ZHANG JINYAN SUN +2 位作者 BAILEI SUN CHENYANG GAO HUI GONG 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2013年第4期11-18,共8页
Near infrared spectroscopy(NIRS)is generally accepted as a functional brain imaging technology for brain activation study.With multichannel highly sensitive NIRS instruments,it has become possible to assess functional... Near infrared spectroscopy(NIRS)is generally accepted as a functional brain imaging technology for brain activation study.With multichannel highly sensitive NIRS instruments,it has become possible to assess functional connectivity of different brain negions by NIRS.However,the feasibility needs to be validated in complex cognitive activities.In this study,we recorded the hemodynamic activity of the bilateral prefrontal cortex(PFC)during a color-word matching Stroop task.Wavelet transform coberence(WTC)analysis was applied to ascss the functional conectivity of all homologous channel pairs within the left/right PFC.Both the behavioral and brain activ ation results showed signifcant Stroop effects.The results of WTC analysis revealed that,bilateral functional connectivity was significantly stronger during both the incongruent stimuli and neutral stimuli compared to that of the rest period.It also showed significant Stroop effect.Our findings demonstrate that,NIRS bcomes a valuable tool to elucidate the functional conectivity of brain cortex in complex cognitive activities. 展开更多
关键词 Near infrared spectroscopy bilateral functional connectivity wavelet transform coherence complex cognitive activities
下载PDF
Cortical activation pattern during shoulder simple versus vibration exercises: a functional near infrared spectroscopy study
16
作者 Sung Ho Jang Sang Seok Yeo +2 位作者 Seung Hyun Lee Sang Hyun Jin Mi Young Lee 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第8期1294-1298,共5页
To date, the cortical effect of exercise has not been fully elucidated. Using the functional near infrared spectroscopy, we attempted to compare the cortical effect between shoulder vibration exercise and shoulder sim... To date, the cortical effect of exercise has not been fully elucidated. Using the functional near infrared spectroscopy, we attempted to compare the cortical effect between shoulder vibration exercise and shoulder simple exercise. Eight healthy subjects were recruited for this study. Two different exercise tasks(shoulder vibration exercise using the flexible pole and shoulder simple exercise) were performed using a block paradigm. We measured the values of oxygenated hemoglobin in the four regions of interest: the primary sensory-motor cortex(SM1 total, arm somatotopy, and leg and trunk somatotopy), the premotor cortex, the supplementary motor area, and the prefrontal cortex. During shoulder vibration exercise and shoulder simple exercise, cortical activation was observed in SM1(total, arm somatotopy, and leg and trunk somatotopy), premotor cortex, supplementary motor area, and prefrontal cortex. Higher oxygenated hemoglobin values were also observed in the areas of arm somatotopy of SM1 compared with those of other regions of interest. However, no significant difference in the arm somatotopy of SM1 was observed between the two exercises. By contrast, in the leg and trunk somatotopy of SM1, shoulder vibration exercise led to a significantly higher oxy-hemoglobin value than shoulder simple exercise. These two exercises may result in cortical activation effects for the motor areas relevant to the shoulder exercise, especially in the arm somatotopy of SM1. However, shoulder vibration exercise has an additional cortical activation effect for the leg and trunk somatotopy of SM1. 展开更多
关键词 nerve regeneration functional near infrared spectroscopy cortical activation shoulder vibrationexercise flexible pole neural regeneration
下载PDF
Right prefrontal cortex is activated for perceiving postural limits: a functional near-infrared spectroscopy study
17
作者 Noriyuki Kamata Yoshimi Matsuo +2 位作者 Ayako Matsuya Satoru Inoue Kazuo Abe 《Health》 2009年第3期239-243,共5页
The purpose of this study was to investigate neuronal mechanisms active during the percep-tion of forward postural limits in a standing po-sition and to specify fall-related brain activity using optical functional nea... The purpose of this study was to investigate neuronal mechanisms active during the percep-tion of forward postural limits in a standing po-sition and to specify fall-related brain activity using optical functional near-infrared spectros-copy. The study group included six right-handed, healthy female volunteers (range: 19, 20 years). The optical imaging device comprised 16 opto-des designed to provide 24-channel recording of changes in hemoglobin oxygenation. We meas-ured the changes of oxygenated hemoglobin levels in the frontal region when subjects per-ceived reachability in a standing position. Com- pared with those in other regions, the oxygen-ated hemoglobin levels in the right frontal region compatible with the right prefrontal cortex sig-nificantly increased. This result suggests that brain activities in the right prefrontal cortex are related to perception of reachability. Overesti-mation of postural limits has been reported as one of the risk factor for falling. This overesti-mation might be induced by dysfunction in the prefrontal cortex, resulting in a failure to inhibit a motor program that would have caused a loss of balance in reaching. Activation of the right prefrontal cortex may be a key factor for pre-venting accidental falls in the elderly and in pa-tients with neurological disorders. 展开更多
关键词 POSTURAL Limits FALLS functional NEAR-infrared spectroscopy (fnirs) PREFRONTAL CORTEX (PFC)
下载PDF
Odorant discrimination using functional near-infrared spectroscopy of the main olfactory bulb in rats
18
作者 Inwon Jung Kyungjin You +3 位作者 Hyunchool Shin Chinsu Koh Hyungcheul Shin Jaewoo Shin 《Journal of Measurement Science and Instrumentation》 CAS 2013年第1期89-93,共5页
We characterize the hemodynamic response changes near-infrared spectroscopy (NIRS) during the presentation of in the main olfactory bulb (MOB) of anesthetized rats with three different odorants: (i) plain air a... We characterize the hemodynamic response changes near-infrared spectroscopy (NIRS) during the presentation of in the main olfactory bulb (MOB) of anesthetized rats with three different odorants: (i) plain air as a reference (Blank), (ii) 2-heptanone (HEP), and (iii) isopropylbenzene (Ib). Odorants generate different changes in the concentrations of oxy- hemoglobin. Our results suggest that NIRS technology might be useful in discriminating various odorants in a non-invasive manner using animals with a superb olfactory system. 展开更多
关键词 brain-machine interface(BMI) functional near-infrared spectroscopy(fnirs) main olfactory bulb(MOB) oxyhemoglobin(HbO2) Beer-Lambert law maximum likelihood estimation(MLE)
下载PDF
ASSESSING WORKING MEMORY IN REAL-LIFE SITUATIONS WITH FUNCTIONAL NEAR-INFRARED SPECTROSCOPY
19
作者 TING LI LI LI +1 位作者 QINGMING LUO HUI GONG 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2009年第4期423-430,共8页
Working memory is one of the most important functions in our brain,which has been widely studied with unreal-life measured technologies.A functional near-infrared spectroscopy(fNIRS)instrument with a portable and low-... Working memory is one of the most important functions in our brain,which has been widely studied with unreal-life measured technologies.A functional near-infrared spectroscopy(fNIRS)instrument with a portable and low-cost design is developed,which is capable of providing hemodynamic measurement associated with brain function in real-life situations.Using this instrument,we performed working memory studies involved in Chinese words encoding,verbal,and spatial stem recognition,which are mainly studied with other technologies.Our results show that fNIRS can well assess working memory activities,in comparison with the reported results mainly using other methodologies.Furthermore,we find that hemodynamic change in the prefrontal cortex during all working memory tasks is highly associated with subjects’behavioral data.fNIRS is shown to be a promising alternative to the current methodologies for studying or assessing functional brain activities in natural condition. 展开更多
关键词 functional near-infrared spectroscopy(fnirs) working memory prefrontal cortex(PFC) oxy-hemoglobin deoxy-hemoglobin
下载PDF
Investigation.of human visual cortex responses to flickering light using functional near infrared spectroscopy and constrained ICA
20
作者 Nguyen Duc Thang Vo Van Toi +2 位作者 Le Giang Tran Nguyen Huynh Minh Tam Lan Anh Trinh 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2014年第6期77-89,共13页
The human visual sensitivity to the flickering light has been under investigation for decades.The finding of research in this area can contribute to the understanding of human visual system mechanism and visual disord... The human visual sensitivity to the flickering light has been under investigation for decades.The finding of research in this area can contribute to the understanding of human visual system mechanism and visual disorders,and establishing diagnosis and treatment of diseases.The aim of this study is to investigate the ffects of the flickering light to the visual cortex by monitoring the hemodynamic responses of the brain with the functional near infrared spectrosoopy(ENIRS)method.Since the acquired fNIRS signals are afected by physiological factors and measurement artifacts,constrained independent component analysis(eICA)was applied to extract the actual fNIRS responses from the obtained data.The experimental results revealed significant changes(p<0.0001)of the hemodynamic responses of the visual cortex.from the baseline when the flickering stimulation was activated.With the uses of cICA,the contrast to noise ratio(CNR),reflecting the contrast of hemodynamic concentration between rest and task,became larger.This indicated the improvement of the NIRS signals when the noise was eliminated.In subsequent studies,statistical analysis was used to infer the correlation between the NIRS signals and the visual stimulus.We found that there was a slight decrease of the oxygenated hemoglobin con-centration(about 5.69%)over four frequencies when the modulation increased.However,the variations of oxy and deoxy-hemoglobin were not statistically significant. 展开更多
关键词 Papillometre visual stimulation functional near infrared spectroscopy constrained independent component analysis
下载PDF
上一页 1 2 23 下一页 到第
使用帮助 返回顶部