Maize stalk rot reduces grain yield and quality.Information about the genetics of resistance to maize stalk rot could help breeders design effective breeding strategies for the trait.Genomic prediction may be a more e...Maize stalk rot reduces grain yield and quality.Information about the genetics of resistance to maize stalk rot could help breeders design effective breeding strategies for the trait.Genomic prediction may be a more effective breeding strategy for stalk-rot resistance than marker-assisted selection.We performed a genome-wide association study(GWAS)and genomic prediction of resistance in testcross hybrids of 677 inbred lines from the Tuxpe?o and non-Tuxpe?o heterotic pools grown in three environments and genotyped with 200,681 single-nucleotide polymorphisms(SNPs).Eighteen SNPs associated with stalk rot shared genomic regions with gene families previously associated with plant biotic and abiotic responses.More favorable SNP haplotypes traced to tropical than to temperate progenitors of the inbred lines.Incorporating genotype-by-environment(G×E)interaction increased genomic prediction accuracy.展开更多
Sorghum [<i><span style="font-family:Verdana;">Sorghum bicolor</span></i><span style="font-family:Verdana;"> (L.) Moench] is a high-yielding, nutrient-use efficient, a...Sorghum [<i><span style="font-family:Verdana;">Sorghum bicolor</span></i><span style="font-family:Verdana;"> (L.) Moench] is a high-yielding, nutrient-use efficient, and drought tolerant crop that can be cultivated on over 80 per cent of the world’s agricultural land. However, a number of biotic and abiotic factors are limiting grain yield increase. Diseases (leaf and grain) are considered as one of the major biotic factors hindering sorghum productivity in the highland and intermediate altitude sorghum growing areas of Ethiopia. In addition, the yield performance of crop varieties is highly influenced by genotype × environment (G × E) interaction which is the major focus of researchers while generating improved varieties. In Ethiopia, high yielding and stable varieties that withstand biotic stress in the highland areas are limited. In line with this, the yield performance of 21 sorghum genotypes and one standard check were evaluated across 14 environments with the objectives of estimating magnitude G </span><span style="font-family:Verdana;">× E interaction for grain yield and to identify high yielder and stable genotypes across environments. The experiment was laid out using Randomized Complete Block Design with three replications in all environments. The combined analysis of variance across environments revealed highly significant differences among environments, genotypes and G × E interactions of grain yield suggesting further analysis of the G × E interaction. The results of the combined AMMI analysis of variance indicated that the total variation in grain yield was attributed to environments effects 71.21%, genotypes effects 4.52% and G × E interactions effects 24.27% indicating the major sources of variation. Genotypes 2006AN7010 and 2006AN7011 were high yielder and they were stable across environments and one variety has been released for commercial production and can be used as parental lines for genetic improvement in the sorghum improvement program. In general, this research study revealed the importance of evaluating sorghum genotypes for their yield and stability across diverse highland areas of Ethiopia before releasing for commercial production.</span>展开更多
Objective: To study the disruption of co- localization of human Daxx(hDaxx) with promyelocytic leukemia protein(PML) at the PML oncogenic domains (PODs) by the interaction of hDaxx with adenovirus(Ad) 12 E1B 55 Kiloda...Objective: To study the disruption of co- localization of human Daxx(hDaxx) with promyelocytic leukemia protein(PML) at the PML oncogenic domains (PODs) by the interaction of hDaxx with adenovirus(Ad) 12 E1B 55 Kilodalton Oncoprotein (Ad12 E1B 55kD). Methods: The direct binding reaction of hDaxx and Ad12 E1B 55kD was analyzed by coimmunoprecipitation and Western blotting in vivo or in vitro. The interaction of hDaxx with Ad12 E1B 55kD was studied using yeast two-hybrid assay. Results: hDaxx bounded directly to Ad12 E1B 55kD in vivo and in vitro. hDaxx interacted with full length Ad12 E1B 55kD. Conclusion: Transcriptional regulator hDaxx directly binds to and interacts with Ad12 E1B 55kD.展开更多
The mechanism and interaction among Rb/p16, Rb/E2F1 and HDAC1 proteins in gallbladder carcinoma were investigated. By using the immunoprecipitation method, the interactions among Rb, p16, E2F1, HDAC1 proteins in gallb...The mechanism and interaction among Rb/p16, Rb/E2F1 and HDAC1 proteins in gallbladder carcinoma were investigated. By using the immunoprecipitation method, the interactions among Rb, p16, E2F1, HDAC1 proteins in gallbladder carcinoma cell line (Mz-ChA-1) were studied. It was found that there were Rb and E2F1 proteins in the precipitates with anti-HDAC1, and there were HDAC1 and E2F1 proteins in the precipitate with anti-Rb. It was concluded that there are specific interactions among Rb, HDAC1 and E2F1 proteins in gallbladder carcinoma, indicating the existence of the direct Rb/E2F1/HDAC1 signal transduction pathway. There is no direct relationship between p16 proteins with Rb, HDAC1, and E2F1 proteins.展开更多
With the increasing demand for petroleum resources and environmental issues,new energy electric vehicles are increasingly being used.However,the large number of electric vehicles connected to the grid has brought new ...With the increasing demand for petroleum resources and environmental issues,new energy electric vehicles are increasingly being used.However,the large number of electric vehicles connected to the grid has brought new challenges to the operation of the grid.Firstly,A novel bidirectional interaction model is established based on modulation theory with nonlinear loads.Then,the electric energy measuring scheme of EVs for V2G is derived under the conditions of distorted power loads.The scheme is composed of fundamental electric energy,fundamental-distorted electric energy,distorted-fundamental electric energy and distorted electric energy.And the characteristics of each electric energy are analyzed.Finally,the correctness of the model and energy measurement method is verified by three simulation cases:the impact signals,the fluctuating signals,and the harmonic signals.展开更多
With the problem of global energy shortage and people’s awareness of energy saving, electric vehicles receive world-wide attention from government to business. Then the load of the power grid will rapidly increase in...With the problem of global energy shortage and people’s awareness of energy saving, electric vehicles receive world-wide attention from government to business. Then the load of the power grid will rapidly increase in a short term, and a series of effects will bring to the power grid operation, management, production and planning. With the large-scale penetration of electric vehicles and distributed energy gradually increased, if they can be effectively controlled and regulated, they can play the roles of load shifting, stabling intermittent renewable energy sources, providing emergency power supply and so on. Otherwise they may have a negative impact, which calls for a good interaction of electric vehicles and power grid. Analyzed the status of the current study on the interaction between the electric vehicles and the power grid, this paper builds the material basis, information architecture and the corresponding control method for the interaction from the aspect of the energy and information exchanging, and then discusses the key issues, which makes a useful exploration for the further research.展开更多
Traditional ligand-field theory has to be improved by taking into account both 'pure electronic' contribution and electron-phonon interaction one (including lattice-vibrational relaxation energy). By means of ...Traditional ligand-field theory has to be improved by taking into account both 'pure electronic' contribution and electron-phonon interaction one (including lattice-vibrational relaxation energy). By means of improved ligand-field theory, R1, R2, R'3, R'2, and R'1 lines, U band, ground-state zero-field-splitting (GSZFS), and ground-state g factors of ruby and/or GSGG: Cr3+ as well as thermal shifts of GSZFS, R1 line and R2 line of ruby have been calculated.The results are in very good agreement with the experimental data. Moreover, it is found that the value of cubic-field parameter given by traditional ligand-field theory is inappropriately large. For thermal shifts of GSZFS, R1 line and R2 line of ruby, several conclusions have also been obtained.展开更多
We have carried out magneto-transport measurements for single crystal SrMnSb2. Clear Shubnikov-de Haas oscil- lations were resolved at relatively low magnetic field around 4 T, revealing a quasi-2D Fermi surface. We o...We have carried out magneto-transport measurements for single crystal SrMnSb2. Clear Shubnikov-de Haas oscil- lations were resolved at relatively low magnetic field around 4 T, revealing a quasi-2D Fermi surface. We observed a development of quantized plateaus in Hall resistance (Rxy) at high pulsed fields up to 60 T. Due to the strong 2D confine- ment and layered properties of the samples, we interpreted the observation as bulk quantum Hall effect that is contributed by the parallel 2D conduction channels. Moreover, the spin degeneracy was lifted leading to Landau level splitting. The presence of anisotropic g factor and the formation of the oscillation beating pattern reveal a strong spin-orbit interaction in the SrMnSb2 system.展开更多
Agent negotiation has become increasingly important since the advent of electronic commerce.There are two kinds of interactions in the process of agent negotiation.One is the interaction between different agents,and t...Agent negotiation has become increasingly important since the advent of electronic commerce.There are two kinds of interactions in the process of agent negotiation.One is the interaction between different agents,and the other is the interaction between the agent and the human user.In this paper,firstly,we introduce Q language,a scenario description language for designing interactions between agents and human users.Then we propose an integrating interaction framework for agent negotiation,in which both kinds of interactions are described by Q scenario.Our framework can make the interaction process open and easy to be understood by the users.Users can understand how the negotiation process goes and what is happening in the system including some erroneous or inappropriate actions caused by the negotiation agent.This gives the users a chance to terminate or change the behavior of negotiation agent in time to avoid unfavorable negotiation outcome.In addition,users can customize the agent's behaviors through visible interactions with it.展开更多
Objectives Both apolipoprotein(Apo)C-Ⅲgene polymorphism and alcohol consumption have been associated with increased serum triglyceride(TG) levels,but their interactions on serum TG levels are not well known.The prese...Objectives Both apolipoprotein(Apo)C-Ⅲgene polymorphism and alcohol consumption have been associated with increased serum triglyceride(TG) levels,but their interactions on serum TG levels are not well known.The present study was undertaken to detect the interactions of the ApoC-Ⅲ3238C】G(rs5128) polymorphism and alcohol consumption on serum TG levels.Methods A total of 516 unrelated nondrinkers and 514 drinkers aged 15-89 were randomly selected from our previous stratified randomized cluster samples. Genotyping of the ApoC-Ⅲ3238C】G was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis,and then confirmed by direct sequencing.Interactions of the ApoC-Ⅲ3238C】G genotype and alcohol consumption was assessed by using a cross-product term between genotypes and the afore-mentioned factor.Results Serum total cholesterol(TC), TG,high-density lipoprotein cholesterol(HDL-C),ApoA-I and ApoB levels were higher in drinkers than in nondrinkers (P【0.05-0.001).There was no significant difference in the genotypic and allelic frequencies between the two groups. Serum TG levels in nondrinkers were higher in CG genotype than in CC genotype(P【0,01).Serum TC,TG,low-density lipoprotein cholesterol(LDL-C) and ApoB levels in drinkers were higher in GG genotype than in CC or CG genotype(P【0.01 for all).Serum HDL-C levels in drinkers were higher in CG genotype than in CC genotype(P【0.01).Serum TC, TG,HDL-C and ApoA-I levels in CC genotype,TC,HDL-C, ApoA-I levels and the ratio of ApoA-I to ApoB in CG genotype, and TC,TG,LDL-C,ApoA-I and ApoB levels in GG genotype were higher in drinkers than in nondrinkers(P【0.05-0.01).But the ratio of ApoA-I to ApoB in GG genotype was lower in drinkers than in nondrinkers(P【0.01). Multivariate logistic regression analysis showed that the levels of TC,TG and ApoB were correlated with genotype in non drinkers(P【0.05 for all).The levels of TC,LDL-C and ApoB were associated with genotype in drinkers(P【0.01 for all). Serum lipid parameters were also correlated with age,sex,alcohol consumption,cigarette smoking,blood pressure,body weight,and body mass index in both groups.Conclusions This study suggests that the ApoC-Ⅲ3238CG heterozygotes benefited more from alcohol consumption than CC and GG homozygotes in increasing serum levels of HDL-C,ApoA-I, and the ratio of ApoA-I to ApoB,and lowering serum levels of TC and TG.展开更多
Interaction is one of the crucial features of multi-agent systems, in which there are two kinds of interaction: agent-to-agent and human-to-agent. In order to unify the two kinds of interaction while designing multi-a...Interaction is one of the crucial features of multi-agent systems, in which there are two kinds of interaction: agent-to-agent and human-to-agent. In order to unify the two kinds of interaction while designing multi-agent systems, this paper introduces Qlanguage-a scenario description language for designing interaction among agents and humans. Based on Q,we propose an integrating interaction framework system for multi-agent coordination, in which Qscenarios are used to uniformly describe both kinds of interactions. Being in accordance to the characteristics of Qlanguage, the Q-basedframework makes the interaction process open and easily understood by the users. Additionally, it makes specific applications of multi-agent systems easy to be established by application designers. By applying agent negotiation in agent-mediated e-commerce and agent cooperation in interoperable information query on the Semantic Web, we illustrate how the presented framework for multi-agent coordination is implemented in concrete applications. At the same time, these two different applications also demonstrate usability of the presented framework and verify validity of Qlanguage.展开更多
基金funded by the CGIAR Research Program(CRP)on MAIZEthe USAID through the Accelerating Genetic Gains Supplemental Project(Amend.No.9 MTO 069033),and the One CGIAR Initiative on Accelerated Breeding+1 种基金funding from the governments of Australia,Belgium,Canada,China,France,India,Japan,the Republic of Korea,Mexico,the Netherlands,New Zealand,Norway,Sweden,Switzerland,the United Kingdom,the United States,and the World Banksupported by the China Scholarship Council。
文摘Maize stalk rot reduces grain yield and quality.Information about the genetics of resistance to maize stalk rot could help breeders design effective breeding strategies for the trait.Genomic prediction may be a more effective breeding strategy for stalk-rot resistance than marker-assisted selection.We performed a genome-wide association study(GWAS)and genomic prediction of resistance in testcross hybrids of 677 inbred lines from the Tuxpe?o and non-Tuxpe?o heterotic pools grown in three environments and genotyped with 200,681 single-nucleotide polymorphisms(SNPs).Eighteen SNPs associated with stalk rot shared genomic regions with gene families previously associated with plant biotic and abiotic responses.More favorable SNP haplotypes traced to tropical than to temperate progenitors of the inbred lines.Incorporating genotype-by-environment(G×E)interaction increased genomic prediction accuracy.
文摘Sorghum [<i><span style="font-family:Verdana;">Sorghum bicolor</span></i><span style="font-family:Verdana;"> (L.) Moench] is a high-yielding, nutrient-use efficient, and drought tolerant crop that can be cultivated on over 80 per cent of the world’s agricultural land. However, a number of biotic and abiotic factors are limiting grain yield increase. Diseases (leaf and grain) are considered as one of the major biotic factors hindering sorghum productivity in the highland and intermediate altitude sorghum growing areas of Ethiopia. In addition, the yield performance of crop varieties is highly influenced by genotype × environment (G × E) interaction which is the major focus of researchers while generating improved varieties. In Ethiopia, high yielding and stable varieties that withstand biotic stress in the highland areas are limited. In line with this, the yield performance of 21 sorghum genotypes and one standard check were evaluated across 14 environments with the objectives of estimating magnitude G </span><span style="font-family:Verdana;">× E interaction for grain yield and to identify high yielder and stable genotypes across environments. The experiment was laid out using Randomized Complete Block Design with three replications in all environments. The combined analysis of variance across environments revealed highly significant differences among environments, genotypes and G × E interactions of grain yield suggesting further analysis of the G × E interaction. The results of the combined AMMI analysis of variance indicated that the total variation in grain yield was attributed to environments effects 71.21%, genotypes effects 4.52% and G × E interactions effects 24.27% indicating the major sources of variation. Genotypes 2006AN7010 and 2006AN7011 were high yielder and they were stable across environments and one variety has been released for commercial production and can be used as parental lines for genetic improvement in the sorghum improvement program. In general, this research study revealed the importance of evaluating sorghum genotypes for their yield and stability across diverse highland areas of Ethiopia before releasing for commercial production.</span>
基金This work was supported by grants from Ministry of Education of P.R. China (No. 2000-65).
文摘Objective: To study the disruption of co- localization of human Daxx(hDaxx) with promyelocytic leukemia protein(PML) at the PML oncogenic domains (PODs) by the interaction of hDaxx with adenovirus(Ad) 12 E1B 55 Kilodalton Oncoprotein (Ad12 E1B 55kD). Methods: The direct binding reaction of hDaxx and Ad12 E1B 55kD was analyzed by coimmunoprecipitation and Western blotting in vivo or in vitro. The interaction of hDaxx with Ad12 E1B 55kD was studied using yeast two-hybrid assay. Results: hDaxx bounded directly to Ad12 E1B 55kD in vivo and in vitro. hDaxx interacted with full length Ad12 E1B 55kD. Conclusion: Transcriptional regulator hDaxx directly binds to and interacts with Ad12 E1B 55kD.
文摘The mechanism and interaction among Rb/p16, Rb/E2F1 and HDAC1 proteins in gallbladder carcinoma were investigated. By using the immunoprecipitation method, the interactions among Rb, p16, E2F1, HDAC1 proteins in gallbladder carcinoma cell line (Mz-ChA-1) were studied. It was found that there were Rb and E2F1 proteins in the precipitates with anti-HDAC1, and there were HDAC1 and E2F1 proteins in the precipitate with anti-Rb. It was concluded that there are specific interactions among Rb, HDAC1 and E2F1 proteins in gallbladder carcinoma, indicating the existence of the direct Rb/E2F1/HDAC1 signal transduction pathway. There is no direct relationship between p16 proteins with Rb, HDAC1, and E2F1 proteins.
基金This work is supported by China Postdoctoral Science Foundation(2021M690798)Guizhou Province Science and Technology Plan Project(No.[2021]General 085)+1 种基金National Natural Science Foundation of China(No.61603034)the Fundamental Research Funds for the Central Universities(Nos.FRF-BD-19-002A,FRF-DF-20-14).
文摘With the increasing demand for petroleum resources and environmental issues,new energy electric vehicles are increasingly being used.However,the large number of electric vehicles connected to the grid has brought new challenges to the operation of the grid.Firstly,A novel bidirectional interaction model is established based on modulation theory with nonlinear loads.Then,the electric energy measuring scheme of EVs for V2G is derived under the conditions of distorted power loads.The scheme is composed of fundamental electric energy,fundamental-distorted electric energy,distorted-fundamental electric energy and distorted electric energy.And the characteristics of each electric energy are analyzed.Finally,the correctness of the model and energy measurement method is verified by three simulation cases:the impact signals,the fluctuating signals,and the harmonic signals.
文摘With the problem of global energy shortage and people’s awareness of energy saving, electric vehicles receive world-wide attention from government to business. Then the load of the power grid will rapidly increase in a short term, and a series of effects will bring to the power grid operation, management, production and planning. With the large-scale penetration of electric vehicles and distributed energy gradually increased, if they can be effectively controlled and regulated, they can play the roles of load shifting, stabling intermittent renewable energy sources, providing emergency power supply and so on. Otherwise they may have a negative impact, which calls for a good interaction of electric vehicles and power grid. Analyzed the status of the current study on the interaction between the electric vehicles and the power grid, this paper builds the material basis, information architecture and the corresponding control method for the interaction from the aspect of the energy and information exchanging, and then discusses the key issues, which makes a useful exploration for the further research.
文摘Traditional ligand-field theory has to be improved by taking into account both 'pure electronic' contribution and electron-phonon interaction one (including lattice-vibrational relaxation energy). By means of improved ligand-field theory, R1, R2, R'3, R'2, and R'1 lines, U band, ground-state zero-field-splitting (GSZFS), and ground-state g factors of ruby and/or GSGG: Cr3+ as well as thermal shifts of GSZFS, R1 line and R2 line of ruby have been calculated.The results are in very good agreement with the experimental data. Moreover, it is found that the value of cubic-field parameter given by traditional ligand-field theory is inappropriately large. For thermal shifts of GSZFS, R1 line and R2 line of ruby, several conclusions have also been obtained.
基金Project supported by the National Key Research and Development Program of China(Grant No.2017YFA0303302)the National Natural Science Foundation of China(Grant Nos.61322407,11474058,and 61674040)
文摘We have carried out magneto-transport measurements for single crystal SrMnSb2. Clear Shubnikov-de Haas oscil- lations were resolved at relatively low magnetic field around 4 T, revealing a quasi-2D Fermi surface. We observed a development of quantized plateaus in Hall resistance (Rxy) at high pulsed fields up to 60 T. Due to the strong 2D confine- ment and layered properties of the samples, we interpreted the observation as bulk quantum Hall effect that is contributed by the parallel 2D conduction channels. Moreover, the spin degeneracy was lifted leading to Landau level splitting. The presence of anisotropic g factor and the formation of the oscillation beating pattern reveal a strong spin-orbit interaction in the SrMnSb2 system.
基金This work is partially supported by the National Natural Science Foundation of China (No. 69973032)AIEJ (Association of International Education, Japan).
文摘Agent negotiation has become increasingly important since the advent of electronic commerce.There are two kinds of interactions in the process of agent negotiation.One is the interaction between different agents,and the other is the interaction between the agent and the human user.In this paper,firstly,we introduce Q language,a scenario description language for designing interactions between agents and human users.Then we propose an integrating interaction framework for agent negotiation,in which both kinds of interactions are described by Q scenario.Our framework can make the interaction process open and easy to be understood by the users.Users can understand how the negotiation process goes and what is happening in the system including some erroneous or inappropriate actions caused by the negotiation agent.This gives the users a chance to terminate or change the behavior of negotiation agent in time to avoid unfavorable negotiation outcome.In addition,users can customize the agent's behaviors through visible interactions with it.
文摘Objectives Both apolipoprotein(Apo)C-Ⅲgene polymorphism and alcohol consumption have been associated with increased serum triglyceride(TG) levels,but their interactions on serum TG levels are not well known.The present study was undertaken to detect the interactions of the ApoC-Ⅲ3238C】G(rs5128) polymorphism and alcohol consumption on serum TG levels.Methods A total of 516 unrelated nondrinkers and 514 drinkers aged 15-89 were randomly selected from our previous stratified randomized cluster samples. Genotyping of the ApoC-Ⅲ3238C】G was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis,and then confirmed by direct sequencing.Interactions of the ApoC-Ⅲ3238C】G genotype and alcohol consumption was assessed by using a cross-product term between genotypes and the afore-mentioned factor.Results Serum total cholesterol(TC), TG,high-density lipoprotein cholesterol(HDL-C),ApoA-I and ApoB levels were higher in drinkers than in nondrinkers (P【0.05-0.001).There was no significant difference in the genotypic and allelic frequencies between the two groups. Serum TG levels in nondrinkers were higher in CG genotype than in CC genotype(P【0,01).Serum TC,TG,low-density lipoprotein cholesterol(LDL-C) and ApoB levels in drinkers were higher in GG genotype than in CC or CG genotype(P【0.01 for all).Serum HDL-C levels in drinkers were higher in CG genotype than in CC genotype(P【0.01).Serum TC, TG,HDL-C and ApoA-I levels in CC genotype,TC,HDL-C, ApoA-I levels and the ratio of ApoA-I to ApoB in CG genotype, and TC,TG,LDL-C,ApoA-I and ApoB levels in GG genotype were higher in drinkers than in nondrinkers(P【0.05-0.01).But the ratio of ApoA-I to ApoB in GG genotype was lower in drinkers than in nondrinkers(P【0.01). Multivariate logistic regression analysis showed that the levels of TC,TG and ApoB were correlated with genotype in non drinkers(P【0.05 for all).The levels of TC,LDL-C and ApoB were associated with genotype in drinkers(P【0.01 for all). Serum lipid parameters were also correlated with age,sex,alcohol consumption,cigarette smoking,blood pressure,body weight,and body mass index in both groups.Conclusions This study suggests that the ApoC-Ⅲ3238CG heterozygotes benefited more from alcohol consumption than CC and GG homozygotes in increasing serum levels of HDL-C,ApoA-I, and the ratio of ApoA-I to ApoB,and lowering serum levels of TC and TG.
文摘Interaction is one of the crucial features of multi-agent systems, in which there are two kinds of interaction: agent-to-agent and human-to-agent. In order to unify the two kinds of interaction while designing multi-agent systems, this paper introduces Qlanguage-a scenario description language for designing interaction among agents and humans. Based on Q,we propose an integrating interaction framework system for multi-agent coordination, in which Qscenarios are used to uniformly describe both kinds of interactions. Being in accordance to the characteristics of Qlanguage, the Q-basedframework makes the interaction process open and easily understood by the users. Additionally, it makes specific applications of multi-agent systems easy to be established by application designers. By applying agent negotiation in agent-mediated e-commerce and agent cooperation in interoperable information query on the Semantic Web, we illustrate how the presented framework for multi-agent coordination is implemented in concrete applications. At the same time, these two different applications also demonstrate usability of the presented framework and verify validity of Qlanguage.