c-ras-P21 and Gamma-glutamyltransferase (G-GT) activity and its isoenzymes in rat liver extracts were measured after partial hepatectomy. There were G-GT activity peaks at 12th and 36th hour after operation, while no ...c-ras-P21 and Gamma-glutamyltransferase (G-GT) activity and its isoenzymes in rat liver extracts were measured after partial hepatectomy. There were G-GT activity peaks at 12th and 36th hour after operation, while no distinct isoenzyme patterns were found. P21 protein expression occurred between 48 and 96 hours after partial hepatectomy. These results suggest that the temporary increase of G-GT and P21 protein level is involved in the prereplica-tive stage of liver regeneration.展开更多
文摘c-ras-P21 and Gamma-glutamyltransferase (G-GT) activity and its isoenzymes in rat liver extracts were measured after partial hepatectomy. There were G-GT activity peaks at 12th and 36th hour after operation, while no distinct isoenzyme patterns were found. P21 protein expression occurred between 48 and 96 hours after partial hepatectomy. These results suggest that the temporary increase of G-GT and P21 protein level is involved in the prereplica-tive stage of liver regeneration.
