Due to the novel applications of flexible pipes conveying fluid in the field of soft robotics and biomedicine,the investigations on the mechanical responses of the pipes have attracted considerable attention.The fluid...Due to the novel applications of flexible pipes conveying fluid in the field of soft robotics and biomedicine,the investigations on the mechanical responses of the pipes have attracted considerable attention.The fluid-structure interaction(FSI)between the pipe with a curved shape and the time-varying internal fluid flow brings a great challenge to the revelation of the dynamical behaviors of flexible pipes,especially when the pipe is highly flexible and usually undergoes large deformations.In this work,the geometrically exact model(GEM)for a curved cantilevered pipe conveying pulsating fluid is developed based on the extended Hamilton's principle.The stability of the curved pipe with three different subtended angles is examined with the consideration of steady fluid flow.Specific attention is concentrated on the large-deformation resonance of circular pipes conveying pulsating fluid,which is often encountered in practical engineering.By constructing bifurcation diagrams,oscillating shapes,phase portraits,time traces,and Poincarémaps,the dynamic responses of the curved pipe under various system parameters are revealed.The mean flow velocity of the pulsating fluid is chosen to be either subcritical or supercritical.The numerical results show that the curved pipe conveying pulsating fluid can exhibit rich dynamical behaviors,including periodic and quasi-periodic motions.It is also found that the preferred instability type of a cantilevered curved pipe conveying steady fluid is mainly in the flutter of the second mode.For a moderate value of the mass ratio,however,a third-mode flutter may occur,which is quite different from that of a straight pipe system.展开更多
At present,the development of e-commerce is slow for agricultural products in China. Taking agricultural workers as the research object,this paper analyzed factors influencing the implementation of e-commerce of agric...At present,the development of e-commerce is slow for agricultural products in China. Taking agricultural workers as the research object,this paper analyzed factors influencing the implementation of e-commerce of agricultural products. Besides,from the enterprise status,market conditions,and groundings,with the aid of the GEM( Groundings-Enterprises-Markets) model,it evaluated the factors influencing the development of e-commerce of agricultural products. Then,using SPSS software,it analyzed factors and came up with improvement recommendations. The results show that 59% of the respondents are willing to conduct e-commerce,and the status of the enterprises,market conditions and groundings are main factors influencing the implementation of e-commerce of agricultural products. Therefore,it is required to increase industrial concentration,promote cooperation between small and medium-sized enterprises( SMEs),and strengthen infrastructure construction,so as to promote the development of e-commerce of agricultural products.展开更多
This paper reviewed the main target,functions,tool( Open Quake software) and research achievements of the Global Earthquake Model( GEM) Foundation,and made a simple prospect on the development and application of proje...This paper reviewed the main target,functions,tool( Open Quake software) and research achievements of the Global Earthquake Model( GEM) Foundation,and made a simple prospect on the development and application of projects of GEM in the future. Learning from GEM and Open Quake is helpful to improve the seismic hazard model of China and enhance the scientificity of the seismic hazard assessment for metropolitans and major engineering facilities near major seismogenic structures.展开更多
Genome-scale metabolic models(GEMs)have been widely used to design cell factories in silico.However,initial flux balance analysis only considers stoichiometry and reaction direction constraints,so it cannot accurately...Genome-scale metabolic models(GEMs)have been widely used to design cell factories in silico.However,initial flux balance analysis only considers stoichiometry and reaction direction constraints,so it cannot accurately describe the distribution of metabolic flux under the control of various regulatory mechanisms.In the recent years,by introducing enzymology,thermodynamics,and other multiomics-based constraints into GEMs,the metabolic state of cells under different conditions was more accurately simulated and a series of algorithms have been presented for microbial phenotypic analysis.Herein,the development of multiconstrained GEMs was reviewed by taking the constraints of enzyme kinetics,thermodynamics,and transcriptional regulatory mechanisms as examples.This review focused on introducing and summarizing GEMs application tools and cases in cell factory design.The challenges and prospects of GEMs development were also discussed.展开更多
基金Project supported by the National Natural Science Foundation of China (Nos.12072119,12325201,and 52205594)the China National Postdoctoral Program for Innovative Talents (No.BX20220118)。
文摘Due to the novel applications of flexible pipes conveying fluid in the field of soft robotics and biomedicine,the investigations on the mechanical responses of the pipes have attracted considerable attention.The fluid-structure interaction(FSI)between the pipe with a curved shape and the time-varying internal fluid flow brings a great challenge to the revelation of the dynamical behaviors of flexible pipes,especially when the pipe is highly flexible and usually undergoes large deformations.In this work,the geometrically exact model(GEM)for a curved cantilevered pipe conveying pulsating fluid is developed based on the extended Hamilton's principle.The stability of the curved pipe with three different subtended angles is examined with the consideration of steady fluid flow.Specific attention is concentrated on the large-deformation resonance of circular pipes conveying pulsating fluid,which is often encountered in practical engineering.By constructing bifurcation diagrams,oscillating shapes,phase portraits,time traces,and Poincarémaps,the dynamic responses of the curved pipe under various system parameters are revealed.The mean flow velocity of the pulsating fluid is chosen to be either subcritical or supercritical.The numerical results show that the curved pipe conveying pulsating fluid can exhibit rich dynamical behaviors,including periodic and quasi-periodic motions.It is also found that the preferred instability type of a cantilevered curved pipe conveying steady fluid is mainly in the flutter of the second mode.For a moderate value of the mass ratio,however,a third-mode flutter may occur,which is quite different from that of a straight pipe system.
文摘At present,the development of e-commerce is slow for agricultural products in China. Taking agricultural workers as the research object,this paper analyzed factors influencing the implementation of e-commerce of agricultural products. Besides,from the enterprise status,market conditions,and groundings,with the aid of the GEM( Groundings-Enterprises-Markets) model,it evaluated the factors influencing the development of e-commerce of agricultural products. Then,using SPSS software,it analyzed factors and came up with improvement recommendations. The results show that 59% of the respondents are willing to conduct e-commerce,and the status of the enterprises,market conditions and groundings are main factors influencing the implementation of e-commerce of agricultural products. Therefore,it is required to increase industrial concentration,promote cooperation between small and medium-sized enterprises( SMEs),and strengthen infrastructure construction,so as to promote the development of e-commerce of agricultural products.
基金sponsored by the Specific Fund of Fundamental Research,Institute of Geophysics,China Earthquake Administration (DQJB16B19)
文摘This paper reviewed the main target,functions,tool( Open Quake software) and research achievements of the Global Earthquake Model( GEM) Foundation,and made a simple prospect on the development and application of projects of GEM in the future. Learning from GEM and Open Quake is helpful to improve the seismic hazard model of China and enhance the scientificity of the seismic hazard assessment for metropolitans and major engineering facilities near major seismogenic structures.
基金This work was financially supported by the Key Research and Development Program of China(2020YFA0908300)the National Natural Science Foundation of China(31870069 and 32021005)the Fundamental Research Funds for the Central Universities(USRP52019A,JUSRP121010,and JUSRP221013).
文摘Genome-scale metabolic models(GEMs)have been widely used to design cell factories in silico.However,initial flux balance analysis only considers stoichiometry and reaction direction constraints,so it cannot accurately describe the distribution of metabolic flux under the control of various regulatory mechanisms.In the recent years,by introducing enzymology,thermodynamics,and other multiomics-based constraints into GEMs,the metabolic state of cells under different conditions was more accurately simulated and a series of algorithms have been presented for microbial phenotypic analysis.Herein,the development of multiconstrained GEMs was reviewed by taking the constraints of enzyme kinetics,thermodynamics,and transcriptional regulatory mechanisms as examples.This review focused on introducing and summarizing GEMs application tools and cases in cell factory design.The challenges and prospects of GEMs development were also discussed.