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GIAC入课考评推动“1+X”职业技能培养研究与实践——以BIM土建计量为例 被引量:1
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作者 温艳芳 《太原城市职业技术学院学报》 2021年第6期81-83,共3页
随着“互联网+”的高速发展,国家职业教育改革在职业院校、应用型本科高校启动并实施试点1+X证书制度,建筑工程计量与计价向信息化、智能化转型,课程建设与考评紧跟步伐实现信息化。通过GIAC-BIM土建计量测评入课建筑工程计量与计价实... 随着“互联网+”的高速发展,国家职业教育改革在职业院校、应用型本科高校启动并实施试点1+X证书制度,建筑工程计量与计价向信息化、智能化转型,课程建设与考评紧跟步伐实现信息化。通过GIAC-BIM土建计量测评入课建筑工程计量与计价实施以赛代考,探讨了GIAC入课考评对于1+X职业技能培养、教师综合教学能力提升、学生综合素质提高的影响,发现GIAC测评认证是推进1+X工程造价数字化应用、BIM职业技能培养的有效途径。 展开更多
关键词 giac 1+X 入课考评 职业技能培养
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HLA配型不合造血干细胞移植GIAC方案100例临床分析 被引量:68
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作者 韩伟 陆道培 +11 位作者 黄晓军 刘开彦 陈欢 许兰平 刘代红 江倩 陈育红 路瑾 王静波 吴彤 董陆佳 任汉云 《中华血液学杂志》 CAS CSCD 北大核心 2004年第8期453-457,共5页
目的 研究人类白细胞抗原 (HLA)配型不合造血干细胞移植 (HSCT)治疗恶性血液病的新移植方案。方法  10 0例恶性血液病患者 ,5 6例为高危病例 ,进行HLA配型至少 1个位点不合的亲缘供者HSCT。采用GIAC移植方案 ,即G CSF动员供者干细胞 ... 目的 研究人类白细胞抗原 (HLA)配型不合造血干细胞移植 (HSCT)治疗恶性血液病的新移植方案。方法  10 0例恶性血液病患者 ,5 6例为高危病例 ,进行HLA配型至少 1个位点不合的亲缘供者HSCT。采用GIAC移植方案 ,即G CSF动员供者干细胞 ,强化、延长的免疫抑制促进植入及预防移植物抗宿主病 (GVHD) ,使用抗胸腺细胞球蛋白 ,以及骨髓及外周血干细胞联合移植。结果 所有患者均达完全供者植入。发生Ⅱ~Ⅳ度急性GVHD(aGVHD) 4 5例 ,累积发生率 4 8.39% ,发生Ⅲ~Ⅳ度aGVHD 12例 ,累积发生率 12 .90 %。 6 1例可评估的患者中 ,发生慢性 (c)GVHD 38例 ,广泛型 11例。复发 12例 ,11例为高危患者 ,3例经供者淋巴细胞输注达再次完全缓解。死亡 2 2例 ,6例死于复发 ,16例死于移植相关合并症。 72例患者无病存活 ,1年预期无病生存率 ,高危组为 (4 7.6 3± 8.4 9) % ,标危组为 (83.5 2± 7.4 1) %。结论 GIAC方案适用于HLA配型不合的HSCT ,是治疗恶性血液病比较安全。 展开更多
关键词 HLA配型 造血干细胞 细胞移植 giac方案 组织相容性试验 粒细胞集落刺激因子 HSCT
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Gravireception in <i>Phycomyces</i>: Threshold Determination on the Sounding Rocket TEXUS 50
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作者 Werner Schmidt 《Journal of Modern Physics》 2015年第10期1381-1389,共9页
Under parabolic flight conditions microgravity is not lower than 3 to 5 times 10-2 g. In contrast to parabolic flights, sounding rocket flights are virtually vibrational-free allowing microgravity as low as 10-5 g. Th... Under parabolic flight conditions microgravity is not lower than 3 to 5 times 10-2 g. In contrast to parabolic flights, sounding rocket flights are virtually vibrational-free allowing microgravity as low as 10-5 g. Thus, a rotating platform serving as centrifuge allows the precise generation of gravitational forces ranging from 5 to 100 mg (not possible during parabolic flights). On this basis we determined the threshold1 for optical reflection/absorption changes in Phycomyces to be lower than 25 × 10-3 g. This compares well with the threshold determination of gravitropism in Phycomyces on a clinostat centrifuge. Kinetics of gravity-induced absorption changes and gravity as generated by the on-board centrifuge do not coincide but show a distinctive hysteresis with a latency of 4 s (75 mg-ramp, pull-up). 展开更多
关键词 MDWS (Micro-Dual Wavelength Spectrophotometer) Δ giac (Differential Gravity-Induced Absorption Change) PHYCOMYCES blakesleeanus Sporangiophore Micro- and HYPERGRAVITY Texus 50 Sounding Rocket Gravireception
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Hyper Gravity-Induced Transients in <i>Phycomyces</i>as Measured by Single Beam Spectrophotometer on the Sounding Rocket TEXUS 50
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作者 Werner Schmidt 《Journal of Modern Physics》 2018年第2期273-286,共14页
In the first paper of two referring to the TEXUS 50 campaign using micro dual wavelength spectrometers (MDWS) we kinetically determined the threshold1 for GIACs (gravity-induced absorption changes) in Phycomyces to be... In the first paper of two referring to the TEXUS 50 campaign using micro dual wavelength spectrometers (MDWS) we kinetically determined the threshold1 for GIACs (gravity-induced absorption changes) in Phycomyces to be lower than 25 × 10&minus;3 g (http://file.scirp.org/pdf/JMP_2015082810060783.pdf). In this second paper, we attended measurement of GIAC-spectra. Unexpectedly, during the upwards movement, i.e. the hypergravity phase up to top acceleration values reaching 11.6 g at 35.4 s after liftoff we observed transient GIAC-spectra ranging from 380 to 750 nm. In addition, during the whole acceleration phase of 68.2 s, another component near 700 nm develops which remains stable during the whole “free fall trajectory parabola” for 381.3 s. The subsequent reentry of the rocket leads to extraordinary deceleration values up 37.8 g, completely destroying Phycomyces sporangiophores excluding their spectral measurement. During the microgravity phase and by centrifuge operation we were unable to detect any GIAC-spectra (in contrast to kinetic MDWS-measurements, first paper). 展开更多
关键词 MDWS (Micro-Dual Wavelength Spectrophotometer) Single Beam SPECTROPHOTOMETER (SBS) Diode Array Spectrometer (USB-2000+ Ocean Optics) giac (Gravity-Induced Absorption Change) PHYCOMYCES blakesleeanus Sporangiophore Micro- and Hypergravity Texus 50 Sounding Rocket Graviperception. HYPER Gravity-Induced Transients
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Dependence of Gravity Induced Absorption Changes on the Earth’s Magnetic Field as Measured during Parabolic Flight Campaigns
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作者 Werner Schmidt 《Journal of Modern Physics》 2013年第11期1546-1553,共8页
Various spectroscopic experiments performed on the AIRBUS ZERO G—located in Bordeaux, France—in the years 2002 to 2012 exhibit minute optical reflection/absorption changes (GIACs) as a result of gravitational change... Various spectroscopic experiments performed on the AIRBUS ZERO G—located in Bordeaux, France—in the years 2002 to 2012 exhibit minute optical reflection/absorption changes (GIACs) as a result of gravitational changes between 0 and 1.8 g in various biological species such as maize, oats, Arabidopsis and particularly Phycomyces sporangiophores. During a flight day, the AIRBUS ZERO G conducts 31 parabolas, each of which lasts about three minutes including a period of 22 s of weightlessness. So far, we participated in 11 parabolic flight campaigns including more than 1000 parabolas performing various kinds of experiments. During our campaigns, we observed an unexplainable variability of the measuring signals (GIACs). Using GPS-positioning systems and three dimensional magnetic field sensors, these finally were traced back to the changing earth’s magnetic field associated with the various flight directions. This is the first time that the interaction of gravity and the Earth’ magnetic field in the primary induction process in living system has been observed. 展开更多
关键词 MDWS(Micro Dual Wavelength Spectrometer) giac(Gravity Induced Absorption Change) AIRBUS-300-ZERO-G Parabolic Flight Micro-and Hypergravity Three Dimensional Earth’s Magnetic Field Global Positioning System(GPS) Google Earth
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