Golgi apparatus,together with endoplasmic reticula,vacuoles and plasma membrane,constitutes the endoplasmic system of plant cells.It plays an important role in the secretion pathway of eukaryotic cells and is responsi...Golgi apparatus,together with endoplasmic reticula,vacuoles and plasma membrane,constitutes the endoplasmic system of plant cells.It plays an important role in the secretion pathway of eukaryotic cells and is responsible for various intracellular events,such as protein classification,protein modification and glycosylation.At present,much less is known about plant Golgi proteins.The research on its function is still insufficient.In order to provide a comprehensive research background and research ideas for related researchers,this paper systematically and comprehensively evaluated the structure of plant endoplasmic system,the common endoplasmic reticulum-Golgi transport pathway in plant cells,various possible transport models between endoplasmic reticula and Golgi bodies,Golgi-associated specific proteins and functions,and Golgi biogenesis pathway.The latest research progress in this field was reviewed and analyzed in detail.This paper will provide an important reference for related researchers to carry out the research of plant Golgi.展开更多
目的探讨高尔基体蛋白73(golgin protein 73,GP73)、甲胎蛋白(alpha fetoprotein,AFP)、γ-谷氨酰转移酶(γ-glutamyltransferase,GGT)联合增强CT扫描对原发性肝癌的诊断价值。方法选取2020年1月至2021年12月湖北六七二中西医结合骨科...目的探讨高尔基体蛋白73(golgin protein 73,GP73)、甲胎蛋白(alpha fetoprotein,AFP)、γ-谷氨酰转移酶(γ-glutamyltransferase,GGT)联合增强CT扫描对原发性肝癌的诊断价值。方法选取2020年1月至2021年12月湖北六七二中西医结合骨科医院收治的原发性肝癌患者、肝硬化患者和同期健康体检人群为研究对象,分别将其纳入肝癌组(n=52)、肝硬化组(n=52)和对照组(n=52)。所有研究对象均进行增强CT扫描及血清GP73、AFP、GGT水平检测,比较三组研究对象的血清GP73、AFP、GGT水平及不同检测方法对原发性肝癌的诊断效能。结果肝癌组患者的血清GP73、AFP、GGT水平均显著高于肝硬化组和对照组(P<0.05);肿瘤最大径≥3cm患者的血清GP73、AFP、GGT水平均显著高于肿瘤最大径<3cm患者(P<0.05);增强CT扫描联合GP73、AFP、GGT检测诊断原发性肝癌的敏感度、特异性、准确率均高于各项单独检测(P<0.05)。结论GP73、AFP、GGT联合增强CT扫描对原发性肝癌具有较高的诊断价值,可有效提高诊断的敏感度、特异性和准确率,诊断效能较高,值得临床推广应用。展开更多
基金Special Fund for the Research Team of Ecological Restoration and Governance Innovation of the Jinsha River Dry and Hot Valley(035200179)2020 Doctoral Research Startup Fund of Panzhihua University(035200254)。
文摘Golgi apparatus,together with endoplasmic reticula,vacuoles and plasma membrane,constitutes the endoplasmic system of plant cells.It plays an important role in the secretion pathway of eukaryotic cells and is responsible for various intracellular events,such as protein classification,protein modification and glycosylation.At present,much less is known about plant Golgi proteins.The research on its function is still insufficient.In order to provide a comprehensive research background and research ideas for related researchers,this paper systematically and comprehensively evaluated the structure of plant endoplasmic system,the common endoplasmic reticulum-Golgi transport pathway in plant cells,various possible transport models between endoplasmic reticula and Golgi bodies,Golgi-associated specific proteins and functions,and Golgi biogenesis pathway.The latest research progress in this field was reviewed and analyzed in detail.This paper will provide an important reference for related researchers to carry out the research of plant Golgi.
文摘目的探讨高尔基体蛋白73(golgin protein 73,GP73)、甲胎蛋白(alpha fetoprotein,AFP)、γ-谷氨酰转移酶(γ-glutamyltransferase,GGT)联合增强CT扫描对原发性肝癌的诊断价值。方法选取2020年1月至2021年12月湖北六七二中西医结合骨科医院收治的原发性肝癌患者、肝硬化患者和同期健康体检人群为研究对象,分别将其纳入肝癌组(n=52)、肝硬化组(n=52)和对照组(n=52)。所有研究对象均进行增强CT扫描及血清GP73、AFP、GGT水平检测,比较三组研究对象的血清GP73、AFP、GGT水平及不同检测方法对原发性肝癌的诊断效能。结果肝癌组患者的血清GP73、AFP、GGT水平均显著高于肝硬化组和对照组(P<0.05);肿瘤最大径≥3cm患者的血清GP73、AFP、GGT水平均显著高于肿瘤最大径<3cm患者(P<0.05);增强CT扫描联合GP73、AFP、GGT检测诊断原发性肝癌的敏感度、特异性、准确率均高于各项单独检测(P<0.05)。结论GP73、AFP、GGT联合增强CT扫描对原发性肝癌具有较高的诊断价值,可有效提高诊断的敏感度、特异性和准确率,诊断效能较高,值得临床推广应用。
