Objective:To observe the effect of electroacupuncture combined with low-frequency pulsed electromagnetic field on bone metabolism in patients with spinal cord injury(SCI).Methods:The 60 SCI patients who met the inclus...Objective:To observe the effect of electroacupuncture combined with low-frequency pulsed electromagnetic field on bone metabolism in patients with spinal cord injury(SCI).Methods:The 60 SCI patients who met the inclusion criteria were randomly divided into 2 groups by means of a random number table.In the control group,30 patients were treated with osteoporosis treatment apparatus.In the observation group,30 patients were treated with osteoporosis treatment apparatus and electroacupuncture at the foot-shaoyangacupoints [Yánglíngquán(阳陵泉GB 34) and Xuánzhōng(悬钟GB 39) of both sides].The treatment was applied once a day,5 days a week,for 8 weeks.Before and after treatment,the changes of indexes in the two groups,including the bone mineral density(BMD),bone gla-containing protein(BGP),serum alkaline phosphatase(ALP),procollagen type I C-peptide(PICP),and 25-hydroxy-vitamin D [25(OH)D],were observed for comparison.Results:After treatment,in the two groups,the BMD and 25(OH)D indexes of the femoral neck,greater trochanter,and Ward’s triangle region were not significantly changed in comparing with those before treatment(P>0.05),while the BGP,ALP,and PICP indexes were significantly higher than those before treatment(P<0.05).After treatment,in the observation group,the BGP and ALP indexes were significantly increased in comparing with those of the control group,and the difference was statistically significant(P<0.05),whilst the BMD,PICP,and 25(OH)D indexes of the femoral neck,greater trochanter,and wards triangle region,were not significantly different in comparing with the control group(P>0.05).Conclusion:The osteoporosis treatment apparatus can improve bone metabolism in SCI patients,and the curative effect can be enhanced when combined with electroacupuncture at foot-shaoyangacupoints.展开更多
基金Supported by Special fund project of science and technology innovation,Wanzhou district,Chongqing:wzstc-042017089。
文摘Objective:To observe the effect of electroacupuncture combined with low-frequency pulsed electromagnetic field on bone metabolism in patients with spinal cord injury(SCI).Methods:The 60 SCI patients who met the inclusion criteria were randomly divided into 2 groups by means of a random number table.In the control group,30 patients were treated with osteoporosis treatment apparatus.In the observation group,30 patients were treated with osteoporosis treatment apparatus and electroacupuncture at the foot-shaoyangacupoints [Yánglíngquán(阳陵泉GB 34) and Xuánzhōng(悬钟GB 39) of both sides].The treatment was applied once a day,5 days a week,for 8 weeks.Before and after treatment,the changes of indexes in the two groups,including the bone mineral density(BMD),bone gla-containing protein(BGP),serum alkaline phosphatase(ALP),procollagen type I C-peptide(PICP),and 25-hydroxy-vitamin D [25(OH)D],were observed for comparison.Results:After treatment,in the two groups,the BMD and 25(OH)D indexes of the femoral neck,greater trochanter,and Ward’s triangle region were not significantly changed in comparing with those before treatment(P>0.05),while the BGP,ALP,and PICP indexes were significantly higher than those before treatment(P<0.05).After treatment,in the observation group,the BGP and ALP indexes were significantly increased in comparing with those of the control group,and the difference was statistically significant(P<0.05),whilst the BMD,PICP,and 25(OH)D indexes of the femoral neck,greater trochanter,and wards triangle region,were not significantly different in comparing with the control group(P>0.05).Conclusion:The osteoporosis treatment apparatus can improve bone metabolism in SCI patients,and the curative effect can be enhanced when combined with electroacupuncture at foot-shaoyangacupoints.