BACKGROUND Gallbladder adenoma is a relatively rare benign tumor with a potential for malignant transformation if found to be greater than 1 cm in size.CASE SUMMARY Herein,we report a case of a 51-year-old female with...BACKGROUND Gallbladder adenoma is a relatively rare benign tumor with a potential for malignant transformation if found to be greater than 1 cm in size.CASE SUMMARY Herein,we report a case of a 51-year-old female with large 3 cm×3 cm mass of gallbladder adenoma that was misdiagnosed as adenocarcinoma due to its clinical presentation.Computed tomography and magnetic resonance imaging scans showed an irregularly shaped cauliflower-like lump in the gallbladder measuring 38 mm×32 mm corresponding to a malignant tumor and several gallbladder stones with low diffusion-weighted imaging and equisignal of T1-weighted imaging and T2-weighted imaging;moreover,the CA 19-9 levels were very high(184.1 U/mL).Pathology reports after tumor resection showed adenoma with moderate epithelial atypia and moderate atypia in the focal area with fine pedicle and no clear infiltration.CONCLUSION Computed tomography and magnetic resonance imaging scans need to be carefully scrutinized in certain rare cases of adenomas with abnormal imaging features.展开更多
We report a case of carcinoma ex pleomorphic adenoma of a sublingual gland in a 70-year-old man.Under a clinical diagnosis of benign salivary gland tumor,excision of the mass with the sublingual salivary gland in an e...We report a case of carcinoma ex pleomorphic adenoma of a sublingual gland in a 70-year-old man.Under a clinical diagnosis of benign salivary gland tumor,excision of the mass with the sublingual salivary gland in an en bloc fashion via an intraoral approach was performed.Histopathologically,there was a rupture of the fibrous capsule and diffuse cell-rich sheets composed of myoepithelial cells with round nuclei were also seen.Immunohistochemically,the cells that composed of cell rich sheets were positive to smooth muscle actin.Final diagnosis of myoepithelial carcinoma ex pleomorphic adenoma was made.展开更多
目的 探讨胆囊腺瘤（AG）及其局部癌变的MRI特征,以提高对该类疾病的诊断水平。方法 回顾性分析经手术病理证实的18例AG患者的MRI资料,其中5例局部癌变。由2名高级职称影像诊断医师分别独立进行图像分析,观察肿瘤的部位、数量、大小、...目的 探讨胆囊腺瘤（AG）及其局部癌变的MRI特征,以提高对该类疾病的诊断水平。方法 回顾性分析经手术病理证实的18例AG患者的MRI资料,其中5例局部癌变。由2名高级职称影像诊断医师分别独立进行图像分析,观察肿瘤的部位、数量、大小、形态、信号、强化程度、肿瘤与胆囊壁的关系及伴随情况。结果 18例中位于胆囊体部10例,底部7例,颈部1例;单发病灶15例,多发3例。13例AG中,最大径〈0.5 cm 2例,均呈乳头状,表面光整,动脉期呈轻度均匀强化。0.5-1 cm 4例,乳头状和椭圆形各2例;表面光整1例,表面不光整并桑葚征3例;动脉期轻度均匀强化1例,中度均匀强化3例。〉1 cm 7例,乳头状1例,椭圆形和菜花状各3例;表面均不光整,并可见桑葚征;增强扫描动脉期中度均匀强化6例,明显强化1例。所有病灶均为窄基底,在T1WI和T2WI上为均匀等信号。5例AG局部癌变病灶（大小？）,椭圆形1例,菜花状4例;边界光整1例,表面不光整并桑葚征4例;窄基底2例,宽基底3例。在T1WI和T2WI上均为均匀等信号;增强扫描动脉期明显均匀强化2例,明显不均匀强化3例。附着处胆囊壁局限性增厚3例,侵犯肝脏1例。结论 胆囊内窄基底肿块伴桑葚征,应考虑AG的诊断;若病灶局部基底增宽、桑葚征减少、明显不均匀强化、附着处胆囊壁局限性增厚或周围组织侵犯,需考虑AG癌变的可能。展开更多
文摘BACKGROUND Gallbladder adenoma is a relatively rare benign tumor with a potential for malignant transformation if found to be greater than 1 cm in size.CASE SUMMARY Herein,we report a case of a 51-year-old female with large 3 cm×3 cm mass of gallbladder adenoma that was misdiagnosed as adenocarcinoma due to its clinical presentation.Computed tomography and magnetic resonance imaging scans showed an irregularly shaped cauliflower-like lump in the gallbladder measuring 38 mm×32 mm corresponding to a malignant tumor and several gallbladder stones with low diffusion-weighted imaging and equisignal of T1-weighted imaging and T2-weighted imaging;moreover,the CA 19-9 levels were very high(184.1 U/mL).Pathology reports after tumor resection showed adenoma with moderate epithelial atypia and moderate atypia in the focal area with fine pedicle and no clear infiltration.CONCLUSION Computed tomography and magnetic resonance imaging scans need to be carefully scrutinized in certain rare cases of adenomas with abnormal imaging features.
文摘We report a case of carcinoma ex pleomorphic adenoma of a sublingual gland in a 70-year-old man.Under a clinical diagnosis of benign salivary gland tumor,excision of the mass with the sublingual salivary gland in an en bloc fashion via an intraoral approach was performed.Histopathologically,there was a rupture of the fibrous capsule and diffuse cell-rich sheets composed of myoepithelial cells with round nuclei were also seen.Immunohistochemically,the cells that composed of cell rich sheets were positive to smooth muscle actin.Final diagnosis of myoepithelial carcinoma ex pleomorphic adenoma was made.
文摘目的 探讨胆囊腺瘤（AG）及其局部癌变的MRI特征,以提高对该类疾病的诊断水平。方法 回顾性分析经手术病理证实的18例AG患者的MRI资料,其中5例局部癌变。由2名高级职称影像诊断医师分别独立进行图像分析,观察肿瘤的部位、数量、大小、形态、信号、强化程度、肿瘤与胆囊壁的关系及伴随情况。结果 18例中位于胆囊体部10例,底部7例,颈部1例;单发病灶15例,多发3例。13例AG中,最大径〈0.5 cm 2例,均呈乳头状,表面光整,动脉期呈轻度均匀强化。0.5-1 cm 4例,乳头状和椭圆形各2例;表面光整1例,表面不光整并桑葚征3例;动脉期轻度均匀强化1例,中度均匀强化3例。〉1 cm 7例,乳头状1例,椭圆形和菜花状各3例;表面均不光整,并可见桑葚征;增强扫描动脉期中度均匀强化6例,明显强化1例。所有病灶均为窄基底,在T1WI和T2WI上为均匀等信号。5例AG局部癌变病灶（大小？）,椭圆形1例,菜花状4例;边界光整1例,表面不光整并桑葚征4例;窄基底2例,宽基底3例。在T1WI和T2WI上均为均匀等信号;增强扫描动脉期明显均匀强化2例,明显不均匀强化3例。附着处胆囊壁局限性增厚3例,侵犯肝脏1例。结论 胆囊内窄基底肿块伴桑葚征,应考虑AG的诊断;若病灶局部基底增宽、桑葚征减少、明显不均匀强化、附着处胆囊壁局限性增厚或周围组织侵犯,需考虑AG癌变的可能。
