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THE MIXING OF GAS-LIQUID FLOW WITH VAPOR AND GAS-SOLID FLOW
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作者 林多敏 蔡树棠 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 1990年第6期513-518,共6页
In the industrial production, the mixing of gas-liquid flow with vapor and gas-solid flow is a very common problem. In the process of the mixing, solid particle-clusters will form, and will have steady radii when the ... In the industrial production, the mixing of gas-liquid flow with vapor and gas-solid flow is a very common problem. In the process of the mixing, solid particle-clusters will form, and will have steady radii when the effect of the gathering of particles is balanced withthat of the breaking of particle-clusters. Then, the population distribution function of size of particles per unit length per unit volume is introduced, and its governingequation is derived on the analogy of the molecular kinetic theory. Finally, when the gas flow is very slow, the expression of steady average radius of particle-clusters is obtained. 展开更多
关键词 THE MIXING OF gas-liquid flow WITH VAPOR AND GAS-SOLID flow GAS
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Measurement of Liquid Concentration Fields Near Interface with Cocurrent Gas-Liquid Flow Absorption Using Holographic Interferometry
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作者 郭莹 袁希钢 +1 位作者 曾爱武 余国琮 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2006年第6X期747-753,共7页
Real-time laser holographic interferometry was applied to measure liquid concentrations of CO2 in the vicinity of gas-liquid free interface under the conditions of cocurrent gas-liquid flow for absorption of CO2 by et... Real-time laser holographic interferometry was applied to measure liquid concentrations of CO2 in the vicinity of gas-liquid free interface under the conditions of cocurrent gas-liquid flow for absorption of CO2 by ethanol. The influences of the Reynolds number on the measurable interface concentration and on the film thickness were discussed. The results show that CO2 concentration decreases exponentially along the mass transfer direction, and the concentration gradient increases as Reynolds number of either liquid or gas increases. CO2 concentrations fluctuate slightly along the direction of flow; on the whole, there is an increase in CO2 concentration. The investiga- tion also demonstrated that film thickness decreases with the increase of Reynolds number of either of the two phases. Sherwood number representing the mass transfer coefficient was finally correlated as a function of the hy- drodynamic parameters and the physical properties. 展开更多
关键词 cocurrent gas-liquid flow ABSORPTION concentration field NEAR INTERFACE HOLOGRAPHIC INTERFEROMETRY
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Numerical Simulation of Gas-Liquid Flow in a Stirred Tank with a Rushton Impeller 被引量:29
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作者 王卫京 毛在砂 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2002年第4期385-395,共11页
The gas-liquid flow field in a stirred tank with a Rushton disk turbine,including the impeller region,was numerically simulated using the improved inner-outer iterative procedure.The characteristic features of the str... The gas-liquid flow field in a stirred tank with a Rushton disk turbine,including the impeller region,was numerically simulated using the improved inner-outer iterative procedure.The characteristic features of the strirred tank,such as gas cavity and accumulation of gas at the two sides of wall baffles,can be captured by the simulation.The simulated results agree well with available experimental data.Since the improved inner-outer iterative algorithm demands no empirical formula and experimental data for the impeller region,and the approach seems generally applicable for simulating gas-liquid stirred tanks. 展开更多
关键词 数值模拟 湍流槽 气-液流混合 鲁施顿叶轮
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Effects of Orifice Orientation and Gas-Liquid Flow Pattern on Initial Bubble Size 被引量:3
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作者 刘长军 梁斌 +1 位作者 唐盛伟 闵恩泽 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2013年第11期1206-1215,共10页
In many gas-liquid processes, the initial bubble size is determined by a series of operation parameters along with the sparger design and gas-liquid flow pattern. Bubble formation models for variant gas-liquid flow pa... In many gas-liquid processes, the initial bubble size is determined by a series of operation parameters along with the sparger design and gas-liquid flow pattern. Bubble formation models for variant gas-liquid flow patterns have been developed based on force balance. The effects of the orientation of gas-liquid flow, gas velocity, liquid velocity and orifice diameter on the initial bubble size have been clarified. In ambient air-water system, the suitable gas-liquid flow pattern is important to obtain smaller bubbles under the low velocity liquid cross-flow conditions with stainless steel spargers. Among the four types of gas-liquid flow patterns discussed, the horizontal orifice in a vertically upward liquid flow produces the smallest initial bubbles. However the orientation effects of gas and liquid flow are found to be insignificant when liquid velocity is higher than 3.2 m·s 1or the orifice diameter is small enough. 展开更多
关键词 气泡 流动模式 流型 气液 孔板 不锈钢排气管 气体流速 液体流速
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Stability of Stratified Gas-Liquid Flow in Horizontal and Near Horizontal Pipes 被引量:3
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作者 顾汉洋 郭烈锦 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2007年第5期619-625,共7页
一粘滞界面的波浪不稳定性的 Kelvin-Helmholtz 标准基于一个短暂一个维的二液体的模型的线性稳定性分析在这篇论文被建议。在这个模型,压力用本地动量平衡而非静水力学的近似被评估。标准在水平、将近水平的管子中预言成层的流动的稳... 一粘滞界面的波浪不稳定性的 Kelvin-Helmholtz 标准基于一个短暂一个维的二液体的模型的线性稳定性分析在这篇论文被建议。在这个模型,压力用本地动量平衡而非静水力学的近似被评估。标准在水平、将近水平的管子中预言成层的流动的稳定性限制很好。界面的不稳定性上的管子倾斜的效果上的试验性、理论的调查被执行。在界面的波浪不稳定性的发作的批评液体高度对管子倾斜感觉迟钝,这被发现。然而,管子倾斜显著地特别为低煤气的速度影响批评表面的液体速度和波浪速度。 展开更多
关键词 水平状态 倾斜状态 气液分层流 界面稳定性
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Numerical Simulations on Countercurrent Gas-Liquid Flow in a PWR Hot Leg with Air-Water Flow in a 1/15th Scale-Model 被引量:2
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作者 N. Minami M. Murase +2 位作者 Y. Utanohara I. Kinoshita A. Tomiyama 《Journal of Energy and Power Engineering》 2011年第6期495-503,共9页
关键词 空气流速 逆流流动 数值模拟 比例模型 气液两相流 水流 反应堆 量热
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An Experimental Analysis of Gas-Liquid Flow Breakdown in a T-Junction
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作者 Lihui Ma Zhuo Han +6 位作者 Wei Li Guangfeng Qi Ran Cheng Yuanyuan Wang Xiangran Mi Xiaohan Zhang Yunfei Li 《Fluid Dynamics & Materials Processing》 EI 2024年第6期1381-1392,共12页
When a gas-liquid two-phase flow(GLTPF)enters a parallel separator through a T-junction,it generally splits unevenly.This phenomenon can seriously affect the operation efficiency and safety of the equipment located do... When a gas-liquid two-phase flow(GLTPF)enters a parallel separator through a T-junction,it generally splits unevenly.This phenomenon can seriously affect the operation efficiency and safety of the equipment located downstream.In order to investigate these aspects and,more specifically,the so-called bias phenomenon(all gas and liquid flowing to one pipe,while the other pipe is a liquid column that fluctuates up and down),laboratory experiments were carried out by using a T-junction connected to two parallel vertical pipes.Moreover,a GLTPF prediction model based on the principle of minimum potential energy was introduced.The research results indicate that this model can accurately predict the GLTPF state in parallel risers.The boundary of the slug flow and the churn flow in the opposite pipe can be predicted.Overall,according to the results,the pressure drop curves of the two-phase flow in the parallel risers are basically the same when there is no bias phenomenon,but the pressure drop in the parallel riser displays a large deviation when there is a slug flow-churn flow.Only when the parallel riser is in a state of asymmetric flow and one of the risers produces churn flow,the two-phase flow is prone to produce the bias phenomenon. 展开更多
关键词 Two-phase flow T-junction split model entrance effect mechanism model improved model
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4D-Flow MRI在肥厚型心肌病左室流出道血流评估中的价值探索
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作者 徐晶 陈秀玉 +3 位作者 尹刚 闫伟鹏 陆敏杰 赵世华 《磁共振成像》 CAS CSCD 北大核心 2024年第3期56-61,共6页
目的 探索四维血流(four-dimensional flow,4D-Flow)磁共振成像(magnetic resonance imaging,MRI)技术在左心室腔内应用的可行性。材料与方法 本研究为前瞻性、横断面研究,纳入2022年8月至2023年1月于我院接受心脏MRI检查的21例肥厚型... 目的 探索四维血流(four-dimensional flow,4D-Flow)磁共振成像(magnetic resonance imaging,MRI)技术在左心室腔内应用的可行性。材料与方法 本研究为前瞻性、横断面研究,纳入2022年8月至2023年1月于我院接受心脏MRI检查的21例肥厚型心肌病患者,采用3.0 T MRI扫描仪进行二维血流(tow-dimensional flow,2D-Flow)及4D-Flow成像,收集患者一周内进行的超声心动图检查结果。采用组内相关系数(inter-class correlation coefficient,ICC)、变异系数(coefficients of variation,COV)及Bland-Altman分析比较2D-Flow、4D-Flow评估左室流出道峰值流速的可重复性及一致性,并通过Pearson相关性分析探究二者与超声心动图测量结果的关系。结果 2D-Flow和4D-Flow观察者内/观察者间的ICC分别为0.999/0.999和0.995/0.992,COV分别为0.5%/0.5%和2.4%/2.6%。4D-Flow与超声心动图的测量结果呈中度相关,相关系数r值为0.574(P=0.006),但一致性较差,ICC为0.375(P=0.013)。2D-Flow与4D-Flow和超声心动图间无显著的一致性及相关性。结论 4D-Flow技术能够可视化心腔内血流模式,对左室流出道峰值流速的测量具有高度可重复性,且与超声心动图的测量结果具有显著的一致性。 展开更多
关键词 肥厚型心肌病 四维血流 二维血流 心脏磁共振 磁共振成像
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Effects of channel wall wettability on gas-liquid dynamics mass transfer under Taylor flow in a serpentine microchannel 被引量:1
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作者 Xuancheng Liu Hongye Li +4 位作者 Yibing Song Nan Jin Qingqiang Wang Xunli Zhang Yuchao Zhao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第10期192-201,共10页
The wall wettability of microchannels plays an important role in the gas-liquid mass transfer dynamics under Taylor flow.In this study,we regulated the contact angle of the wall surface through surface chemical grafti... The wall wettability of microchannels plays an important role in the gas-liquid mass transfer dynamics under Taylor flow.In this study,we regulated the contact angle of the wall surface through surface chemical grafting polymerization under controlled experimental conditions.The dynamic changes of CO_(2)bubbles flowing along the microchannel were captured by a high-speed video camera mounted on a stereo microscope,whilst a unit cell model was employed to theoretically investigate the gas-liquid mass transfer dynamics.We quantitatively characterized the effects of wall wettability,specifically the contact angle,on the formation mechanism of gas bubbles and mass transfer process experimentally.The results revealed that the gas bubble velocity,the overall volumetric liquid phase mass transfer coefficients(kLa),and the specific interfacial area(a)all increased with the increase of the contact angle.Conversely,gas bubble length and leakage flow decreased.Furthermore,we proposed a new modified model to predict the gas-liquid two-phase mass transfer performance,based on van Baten’s and Yao’s models.Our proposed model was observed to agree reasonably well with experimental observations. 展开更多
关键词 MICROREACTOR Microchannels Mass transfer WETTABILITY Taylor flow gas-liquid two-phase
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肝硬化患者4D flow MRI血流动力学参数与中医证型的相关性研究
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作者 胡勤勤 姜阳 +3 位作者 张玉龙 方玉 梁仁容 杨华 《中国中医急症》 2024年第6期982-985,989,共5页
目的探讨肝硬化患者4D flow MRI血流动力学参数与中医证型的相关性。方法将118例肝硬化患者依据中医辨证分为肝气郁结证、湿热蕴结证、肝肾阴虚证、脾肾阳虚证、瘀血阻络证5个证型,所有患者均行门静脉4D flow MRI检查,统计不同证型肝硬... 目的探讨肝硬化患者4D flow MRI血流动力学参数与中医证型的相关性。方法将118例肝硬化患者依据中医辨证分为肝气郁结证、湿热蕴结证、肝肾阴虚证、脾肾阳虚证、瘀血阻络证5个证型,所有患者均行门静脉4D flow MRI检查,统计不同证型肝硬化患者分布情况,观察门静脉系统(门静脉主干、脾静脉、肠系膜上静脉)的血流动力学参数,包括血流量、流速、壁剪切力等,比较不同证型患者门静脉血流动力学参数差异。结果肝硬化代偿期以肝气郁结证、湿热蕴结证为主,肝硬化失代偿期以脾肾阳虚、瘀血络阻证为主;A级以肝气郁结证、湿热蕴结证为主,B、C级以瘀血络阻证为主。瘀血络阻证肝硬化患者门静脉主干及脾静脉血流量明显高于肝气郁结证、湿热蕴结证患者(P<0.05);脾肾阳虚证门静脉主干血流量明显高于肝气郁结证肝硬化患者(P<0.05);瘀血络阻证肝硬化患者门静脉主干流速及剪切力较肝气郁结证和湿热蕴结证低。结论肝硬化患者中医辨证分型与门静脉血流动力学参数具有一定相关性,4D flow MRI可为肝硬化的中医辨证提供血流动力学参考。 展开更多
关键词 肝硬化 4D flow MRI 血流动力学 中医证型
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基于 Moldflow 的汽车中控台框架翘曲变形分析及优化
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作者 刘巨保 黄建军 +3 位作者 杨明 李峰 张亮 查翔 《塑料工业》 CAS CSCD 北大核心 2024年第3期83-88,共6页
以某汽车中控台框架为研究对象,测量试模样品发现其翘曲变形量超过了装配要求。通过Moldflow软件模拟了该塑件实际的注塑过程,翘曲变形量的模拟值与实测平均值的最大误差为5.98%,发现该塑件翘曲变形的主要因素为冷却不均和收缩不均。本... 以某汽车中控台框架为研究对象,测量试模样品发现其翘曲变形量超过了装配要求。通过Moldflow软件模拟了该塑件实际的注塑过程,翘曲变形量的模拟值与实测平均值的最大误差为5.98%,发现该塑件翘曲变形的主要因素为冷却不均和收缩不均。本文在原物料中添加质量分数为25%的玻璃纤维以及优化工艺参数后,翘曲变形量的模拟值与初始方案相比降低了86.22%。试模验证表明,优化后的翘曲变形量模拟值与实测平均值的最大误差为4.35%,证明了Moldflow软件模拟分析的准确性。试模后各检测点的最大翘曲变形量降到了1.6 mm以下,较优化之前降低了80%以上,为类似大型复杂注塑件的翘曲变形分析及优化提供了思路。 展开更多
关键词 注塑成型 中控台框架 翘曲变形 模流分析 玻璃纤维
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V Flow技术测量颈动脉壁面剪应力的一致性研究
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作者 加依达尔·沙亚哈提 周琛云 陈曼琳 《四川医学》 CAS 2024年第1期28-34,共7页
目的评价血流向量成像(V Flow)技术在测量健康成年人颈动脉壁面剪应力(WSS)中的一致性。方法于2021年2月至2021年3月招募健康成年志愿者20人,由2名不同年资的超声医师使用配备V Flow功能的Mindray Resona 7超声仪和3~9 MHz线阵探头进行... 目的评价血流向量成像(V Flow)技术在测量健康成年人颈动脉壁面剪应力(WSS)中的一致性。方法于2021年2月至2021年3月招募健康成年志愿者20人,由2名不同年资的超声医师使用配备V Flow功能的Mindray Resona 7超声仪和3~9 MHz线阵探头进行双侧颈动脉扫查,分别采集双侧颈总动脉远段、颈总动脉分叉至颈内动脉起始部两段动脉的动态V Flow图像,测量两侧颈总动脉远段的近心端、远心端、分叉处及颈内动脉起始部的前、后壁的WSS,使用组内相关系数(ICC)和Bland-Altman图评估组内一致性及组间一致性。结果双侧颈动脉前、后壁的4个不同节段之间WSS值差异均有统计学意义(P<0.05)。高年资超声医师2次测量结果的一致性结果显示,左侧颈总动脉远段的远心端一致性极好(ICC 0.779),右侧颈总动脉远段的近心端(ICC 0.605)、远心端(ICC 0.585)、颈内动脉起始部(ICC 0.457)、左侧颈总动脉分叉处(ICC 0.606)及颈内动脉起始部(ICC 0.702)一致性均较好;不同年资超声医师的测量结果显示,仅右侧颈总动脉分叉处(ICC 0.486)及左侧颈总动脉远段的远心端(ICC 0.576)一致性较好。结论V Flow技术可显示不同位点间颈动脉WSS之间的差异,其组内一致性较好,但在不同年资超声医师间存在一定的差异。 展开更多
关键词 颈动脉 动脉粥样硬化 壁面剪应力 V flow成像技术
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基于Moldflow软件对薄壁件某塑料喷嘴的注塑方案优化研究
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作者 袁志华 符烜赫 袁博 《机械工程师》 2024年第3期14-17,共4页
喷嘴注塑产品的质量和性能很大程度上由注塑方案和工艺参数所决定,不当的注塑方案和工艺参数会导致充填不足、熔接线过多、翘曲变形量大等问题。为了可以减少生产周期,节约生产成本,利用三维软件UG对喷嘴进行建模,基于模流分析软件Moldf... 喷嘴注塑产品的质量和性能很大程度上由注塑方案和工艺参数所决定,不当的注塑方案和工艺参数会导致充填不足、熔接线过多、翘曲变形量大等问题。为了可以减少生产周期,节约生产成本,利用三维软件UG对喷嘴进行建模,基于模流分析软件Moldflow软件对喷嘴注塑产品进行分析和优化,通过比较点浇口和侧浇口两种方案的分析结果,最终确定该产品点浇口的方案更好。并通过设计正交实验,得到优化后的工艺参数。 展开更多
关键词 喷嘴 MOLDflow 模流分析 浇口位置 正交优化
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A developed transient gas-liquid-solid flow model with hydrate phase transition for solid fluidization exploitation of marine natural gas hydrate reservoirs
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作者 Geng Zhang Jun Li +3 位作者 Gong-Hui Liu Hong-Wei Yang Chao Wang Hong-Lin Huang 《Petroleum Science》 SCIE EI CAS CSCD 2023年第3期1676-1689,共14页
The multiphase flow characteristic is one of the most concerning problems during solid fluidization exploitation of marine natural gas hydrate reservoirs.In this research,a new transient gas-liquid-solid multiphase fl... The multiphase flow characteristic is one of the most concerning problems during solid fluidization exploitation of marine natural gas hydrate reservoirs.In this research,a new transient gas-liquid-solid multiphase flow model with hydrate phase transition was developed.Meanwhile,this model considered the coupling relationship among convective heat transfer,hydrate dynamic decomposition,and multi-phase flow.The model can simulate the change of flow pattern from solid-liquid to gas-liquid-solid flow,and describe the distribution character of volume fraction of phase,wellbore temperature and pressure,and hydrate decomposition rate during transportation.The simulation results indicate that the hydrate decomposition region in the wellbore gradually expands,but the hydrate decomposition rate gradually decreases during the solid fluidization exploitation of hydrate.When mining time lasts for 4 h,and the bottom hole pressure decreases by about 0.4 MPa.Increasing NaCl concentration in seawater helps expand hydrate decomposition regions and improves the wellbore hydrate decomposition rate.When the Nacl mass fraction in seawater reaches 15%,it will raise the hydrate decomposition regions to the whole wellbore.In addition,the higher the wellhead backpressure,the lower the decomposition area and decomposition rate of hydrate in the wellbore.When wellhead backpressure reaches 2 MPa,the volume fraction of gas near the wellhead will reduce to about 12%.This work is expected to provide a theoretical basis for the development of marine hydrate reservoirs. 展开更多
关键词 gas-liquid-solid multiphase flow Solid fluidization Hydrate dynamic decomposition Convective heat transfer
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基于MoldFlow太阳能储能系统下盖成型模拟及应用
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作者 周先保 胡清根 傅海勇 《模具制造》 2024年第2期36-38,共3页
以太阳能储能系统下盖模流分析为例,反复修改流道和浇口截面尺寸与长度以及主流道位置,确定流道尺寸。运用MoldFlow对设计好的流道进行充填分析,以使成型达到流动平衡,并进行冷却、翘曲分析,预测成型缺陷,提出解决措施,为模具设计提供... 以太阳能储能系统下盖模流分析为例,反复修改流道和浇口截面尺寸与长度以及主流道位置,确定流道尺寸。运用MoldFlow对设计好的流道进行充填分析,以使成型达到流动平衡,并进行冷却、翘曲分析,预测成型缺陷,提出解决措施,为模具设计提供浇注系统和冷却系统方案和注射成型工艺参数,并应用于模具设计和实际生产。 展开更多
关键词 太阳能储能系统下盖 流动平衡 成型缺陷
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A transient production prediction method for tight condensate gas wells with multiphase flow
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作者 BAI Wenpeng CHENG Shiqing +3 位作者 WANG Yang CAI Dingning GUO Xinyang GUO Qiao 《Petroleum Exploration and Development》 SCIE 2024年第1期172-179,共8页
Considering the phase behaviors in condensate gas reservoirs and the oil-gas two-phase linear flow and boundary-dominated flow in the reservoir,a method for predicting the relationship between oil saturation and press... Considering the phase behaviors in condensate gas reservoirs and the oil-gas two-phase linear flow and boundary-dominated flow in the reservoir,a method for predicting the relationship between oil saturation and pressure in the full-path of tight condensate gas well is proposed,and a model for predicting the transient production from tight condensate gas wells with multiphase flow is established.The research indicates that the relationship curve between condensate oil saturation and pressure is crucial for calculating the pseudo-pressure.In the early stage of production or in areas far from the wellbore with high reservoir pressure,the condensate oil saturation can be calculated using early-stage production dynamic data through material balance models.In the late stage of production or in areas close to the wellbore with low reservoir pressure,the condensate oil saturation can be calculated using the data of constant composition expansion test.In the middle stages of production or when reservoir pressure is at an intermediate level,the data obtained from the previous two stages can be interpolated to form a complete full-path relationship curve between oil saturation and pressure.Through simulation and field application,the new method is verified to be reliable and practical.It can be applied for prediction of middle-stage and late-stage production of tight condensate gas wells and assessment of single-well recoverable reserves. 展开更多
关键词 tight reservoir condensate gas multiphase flow phase behavior transient flow PSEUDO-PRESSURE production prediction
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Debris Fan Produced by Failure of Canyon-Blocking Pyroclastic Flows
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作者 Michael L. Cummings 《Journal of Water Resource and Protection》 CAS 2024年第5期328-360,共33页
Ash-rich pyroclastic flows from the cataclysmic eruption of Mount Mazama (~7700 yr. B. P.), Cascade volcanic arc, Oregon, entered and blocked the narrow, bedrock-lined canyon of the Williamson River approximately 35 t... Ash-rich pyroclastic flows from the cataclysmic eruption of Mount Mazama (~7700 yr. B. P.), Cascade volcanic arc, Oregon, entered and blocked the narrow, bedrock-lined canyon of the Williamson River approximately 35 to 44 km from the source volcano. The blockage impounded a body of water which then released producing four stratigraphic units in the downstream debris fan. The four stratigraphic units are a boulder core comprised of locally sourced bedrock boulders and three sand-rich units including a fine-grained sand unit, a sandy pumice gravel (±basalt/hydrovolcanic tuff) unit, and a pumice pebble-bearing, crystal-rich sand unit. Hand-drilled auger holes up to ~1.6 m deep were used to obtain samples of the sand-rich units. Units were delimited using surface and down-hole observations, composition and texture, estimated density, statistical parameters of grain size, and vertical and lateral distribution of properties. Overtopping followed by rapid incision into the ash-rich pyroclastic flows progressively cleared the canyon, but a bedrock knickpoint near the head of the canyon limited the volume of debris available for transport to about 0.04 km<sup>3</sup> to 0.08 km<sup>3</sup>. Co-deposition of bedrock boulders and lithic-rich sand was followed by rapid deposition with minimal reworking of remobilized pyroclastics. Continued draining of the impounded lake sent hyperconcentrated flows onto the debris fan depositing pumice-rich gravels that graded upward to crystal-rich sands. 展开更多
关键词 Outburst Flood Mount Mazama Debris Fan Canyon Blockage Pyroclastic flows
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Diagnostic performance of intravascular ultrasound-based fractional flow reserve in evaluating of intermediate left main stenosis
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作者 Yong-Gang SUI Cheng YANG +11 位作者 Chang-Dong GUAN Yan-Lu XU Na-Qiong WU Wei-Xian YANG Yong-Jian WU Ke-Fei DOU Yue-Jin YANG Shu-Bin QIAO Wei YU Bo XU Sheng-Xian TU Jie QIAN 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第1期34-43,共10页
BACKGROUND The recently introduced ultrasonic flow ratio(UFR),is a novel fast computational method to derive fractional flow reserve(FFR)from intravascular ultrasound(IVUS)images.In the present study,we evaluate the d... BACKGROUND The recently introduced ultrasonic flow ratio(UFR),is a novel fast computational method to derive fractional flow reserve(FFR)from intravascular ultrasound(IVUS)images.In the present study,we evaluate the diagnostic performance of UFR in patients with intermediate left main(LM)stenosis.METHODS This is a prospective,single center study enrolling consecutive patients with presence of intermediated LM lesions(diameter stenosis of 30%-80%by visual estimation)underwent IVUS and FFR measurement.An independent core laboratory assessed offline UFR and IVUS-derived minimal lumen area(MLA)in a blinded fashion.RESULTS Both UFR and FFR were successfully achieved in 41 LM patients(mean age,62.0±9.9 years,46.3%diabetes).An acceptable correlation between UFR and FFR was identified(r=0.688,P<0.0001),with an absolute numerical difference of 0.03(standard difference:0.01).The area under the curve(AUC)in diagnosis of physiologically significant coronary stenosis for UFR was 0.94(95%CI:0.87-1.01),which was significantly higher than angiographic identified stenosis>50%(AUC=0.66,P<0.001)and numerically higher than IVUS-derived MLA(AUC=0.82;P=0.09).Patient level diagnostic accuracy,sensitivity and specificity for UFR to identify FFR≤0.80 was 82.9%(95%CI:70.2-95.7),93.1%(95%CI:82.2-100.0),58.3%(95%CI:26.3-90.4),respectively.CONCLUSION In patients with intermediate LM diseases,UFR was proved to be associated with acceptable correlation and high accuracy with pressure wire-based FFR as standard reference.The present study supports the use of UFR for functional evaluation of intermediate LM stenosis. 展开更多
关键词 STENOSIS flow FRACTIONAL
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A multichannel thermal bubble-actuated impedance flow cytometer with on-chip TIA based on CMOS-MEMS
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作者 Shengxun Cai Jianqing Nie +2 位作者 Kun Wang Yimin Guan Demeng Liu 《Journal of Semiconductors》 EI CAS CSCD 2024年第5期41-49,共9页
Electrochemical impedance spectroscopy(EIS)flow cytometry offers the advantages of speed,affordability,and portability in cell analysis and cytometry applications.However,the integration challenges of microfluidic and... Electrochemical impedance spectroscopy(EIS)flow cytometry offers the advantages of speed,affordability,and portability in cell analysis and cytometry applications.However,the integration challenges of microfluidic and EIS read-out circuits hinder the downsizing of cytometry devices.To address this,we developed a thermal-bubble-driven impedance flow cytometric application-specific integrated circuit(ASIC).The thermal-bubble micropump avoids external piping and equipment,enabling high-throughput designs.With a total of 36 cell counting channels,each measuring 884×220μm^(2),the chip significantly enhances the throughput of flow cytometers.Each cell counting channel incorporates a differential trans-impedance amplifier(TIA)to amplify weak biosensing signals.By eliminating the parasitic parameters created at the complementary metal-oxidesemiconductor transistor(CMOS)-micro-electromechanical systems(MEMS)interface,the counting accuracy can be increased.The on-chip TIA can adjust feedback resistance from 5 to 60 kΩto accommodate solutions with different impedances.The chip effectively classifies particles of varying sizes,demonstrated by the average peak voltages of 0.0529 and 0.4510 mV for 7 and 14μm polystyrene beads,respectively.Moreover,the counting accuracies of the chip for polystyrene beads and MSTO-211H cells are both greater than 97.6%.The chip exhibits potential for impedance flow cytometer at low cost,high-throughput,and miniaturization for the application of point-of-care diagnostics. 展开更多
关键词 EIS flow cytometry CMOS-MEMS thermal bubble LAB-ON-CHIP
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Numerical simulation on the multiphase flow and reoxidation of the molten steel in a two-strand tundish during ladle change
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作者 Jingcheng Wang Zhentong Liu +2 位作者 Wei Chen Hongliang Chen Lifeng Zhang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第7期1540-1553,共14页
A 3D mathematical model was proposed to investigate the molten steel–slag–air multiphase flow in a two-strand slab continuous casting(CC)tundish during ladle change.The study focused on the exposure of the molten st... A 3D mathematical model was proposed to investigate the molten steel–slag–air multiphase flow in a two-strand slab continuous casting(CC)tundish during ladle change.The study focused on the exposure of the molten steel and the subsequent reoxidation occurrence.The exposure of the molten steel was calculated using the coupled realizable k–εmodel and volume of fluid(VOF)model.The diffusion of dissolved oxygen was determined by solving the user-defined scalar(UDS)equation.Moreover,the user-defined function(UDF)was used to describe the source term in the UDS equation and determine the oxidation rate and oxidation position.The effect of the refilling speed on the molten steel exposure and dissolved oxygen content was also discussed.Increasing the refilling speed during ladle change reduced the refilling time and the exposure duration of the molten steel.However,the elevated refilling speed enlarged the slag eyes and increased the average dissolved oxygen content within the tundish,thereby exacerbating the reoxidation phenomenon.In addition,the time required for the molten steel with a high dissolved oxygen content to exit the tundish varied with the refilling speed.When the inlet speed was 3.0 m·s^(-1)during ladle change,the molten steel with a high dissolved oxygen content exited the outlet in a short period,reaching a maximum dissolved oxygen content of 0.000525wt%.Conversely,when the inlet speed was 1.8 m·s^(-1),the maximum dissolved oxygen content was 0.000382wt%.The refilling speed during the ladle change process must be appropriately decreased to minimize reoxidation effects and enhance the steel product quality. 展开更多
关键词 TUNDISH ladle change REOXIDATION multiphase flow numerical simulation
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