滇白珠木脂素苷的研究

目的：研究民间药滇白珠（Ｇａｕｌｔｈｅｒｉａｙｕｎｎａｎｅｎｓｉｓ（Ｆｒａｎｃｈ．）Ｒｅｈｄ．）的化学成分。方法：用９５％乙醇提取，硅胶柱色谱和聚酰胺柱色谱分离纯化，通过各种光谱分析鉴定其结构。结果：从正丁醇萃取物中分离鉴定了４个木脂素苷类化合物。其结构分别鉴定为（－）ｉｓｏｌａｒｉｃｉｒｅｓｉｎｏｌ２ａＯβＤｘｙｌｏｐｙｒａｎｏｓｉｄｅ（Ｄ１），（＋）ｌｙｏｎｉｒｅｓｉｎｏｌ２ａＯβＬａｒａｂｉｎｏｐｙｒａｎｏｓｉｄｅ（Ｄ２），（－）５′ｍｅｔｈｏｘｙｉｓｏｌａｒｉｃｉｒｅｓｉｎｏｌ２ａＯβＤｘｙｌｏｐｙｒａｎｏｓｉｄｅ（Ｄ３）和（＋）ｌｙｏｎｉｒｅｓｉｎｏｌ２ａＯβＤｇｌｕｃｏｐｙｒａｎｏｓｉｄｅ（Ｄ４）。结论：化合物Ｄ２为一新化合物，命名为滇白珠苷Ａ（ＧａｕｌｔｈｅｒｏｓｉｄｅＡ），Ｄ１，Ｄ３。

白珠树属5种药用植物木脂素苷含量的比较

<Abstrcat> The contents of lignans glycosides in five species of \%Gaultheria \%Kalm ex L. were measured by HPLC. The resultes proved that 5 plants collected from same place all contain lignans glycosides (LD). The contents of LD in the roots of different plants shows: \%G. fragrantissima>G. leucocarpa \%var. \%yunnanensis>G. leucocarpa \%var. \%cumingiana>G. tetramera>G. griffithiana, \%and these of the above\|ground parts indicate \%G. fragrantissima>G. leucocarpa \%var. \%yunnanensis\%. The contents of LD in the leaves of \%G. fragrantissima \%and \%G. leucocarpa \%var. \%cumingiana \%are higher than those in the stems, and that in stem of \%G. griffithiana \%higher than that in its leaf and root.