A series of(Y_(1-y), Gdy)_(0.95-x)(P_y, V_(1-y))O_4 :0.05Eu^(3+), xBi^(3+)+phosphors have been successfully prepared by a subsection method. The crystal structure, surface morphology and luminescence properties were i...A series of(Y_(1-y), Gdy)_(0.95-x)(P_y, V_(1-y))O_4 :0.05Eu^(3+), xBi^(3+)+phosphors have been successfully prepared by a subsection method. The crystal structure, surface morphology and luminescence properties were investigated. It was found that the sintered samples crystallized in a tetragonal crystal system with space group I_(41)/amd(a = b = 0.7119 nm, c = 0.6290 nm). The products presented rod-like morphology with length of 100-150 nm and width of 50-100 nm. A maximum peak at 619 nm(~5D_0 →~7F_2) was observed in emission spectrum of the phosphors. It was also found that co-doping of Bi^(3+)+, P5+and Gd^(3+)ions into YVO_4:Eu^(3+)can not only made the right edge of the excitation band shift to the long-wavelength region, but also increased the emission intensity at 619 nm sharply and decreased the lifetime of fluorescence decay. These results may expand the application scope of the phosphors.展开更多
AIM: To investigate the performance of Gadofluorine P-enhanced magnetic resonance imaging(MRI) on the diagnosis of diabetes in a streptozotocin(STZ)-induced diabetic rat model.METHODS: Fischer 344 rats were treated wi...AIM: To investigate the performance of Gadofluorine P-enhanced magnetic resonance imaging(MRI) on the diagnosis of diabetes in a streptozotocin(STZ)-induced diabetic rat model.METHODS: Fischer 344 rats were treated with STZ.Rats not treated with STZ served as controls. T1-weighted MRI was performed using a 3T scanner before and after the injection of Gd-DOTA or Gadofluorine P(6 diabetic rats, 5 controls). The normalized signal intensity(SI) and the enhancement ratio(ER) of the pancreas were measured at each time point, and the values were compared between the normal and diabetic rats using the Mann-Whitney test. In addition,the values were correlated with the mean islet number.Optimal cut-off values were calculated using a positive test based on receiver operating characteristics.Intrapancreatic Gd concentration after the injection of each contrast media was measured using laser ablation-inductively coupled plasma-mass spectrometry in a separate set of rats(4 diabetic rats, 4 controls for Gadofluorine P; 2, 2 for Gd-DOTA).RESULTS: The normalized SI and ER of the pancreas using Gd-DOTA were not significantly different between diabetic rats and controls. With Gadofluorine P, the values were significantly higher in the diabetic rats than in the control rats 30 min after injection(P < 0.05). The area under the receiver operating characteristic curve that differentiated diabetic rats from the control group was greater for Gadofluorine P than for Gd-DOTA(0.967 vs 0.667, P = 0.085). An increase in normalized SI 30 min after Gadofluorine P was correlated with a decrease in the mean number of islets(r 2 = 0.510, P = 0.014). Intra-pancreatic Gd was higher in rats with Gadofluorine P injection than Gd-DOTA injection(Gadofluorine P vs Gd-DOTA, 7.37 vs 0.00, P < 0.01). A significant difference in the concentration of intrapancreatic Gd was observed between the control and diabetic animals that were sacrificed 30 min after Gadofluorine P injection(control vs diabetic, 3.25 ng/g vs 10.55 ng/g, P < 0.05)CONCLUSION: In this STZ-induced diabetes rat model,Gadofluorine P-enhanced MRI of the pancreas showed high accuracy in the diagnosis of diabetes.展开更多
黑腹果蝇在北美的群体自1950年后受到 P 转座子的侵入,现在该区域的果蝇几皆成为P 型,而我国境内的果蝇在 P 因子的特征上具有很大的差别,从我们22个品系的杂交实验,子代卵巢解剖的实验测定中可以得到明确的证明。杂交组合正反交结果不...黑腹果蝇在北美的群体自1950年后受到 P 转座子的侵入,现在该区域的果蝇几皆成为P 型,而我国境内的果蝇在 P 因子的特征上具有很大的差别,从我们22个品系的杂交实验,子代卵巢解剖的实验测定中可以得到明确的证明。杂交组合正反交结果不同,证明与细胞质型有关。展开更多
Routine solution reaction of Gd3＋ and p-phenylenediamine-N,N,N′,N′-tetraacetic acid （p-PhDTA） yields a dinuclear complex [Gd2（ox）（p-PhDTA）2（H2O）10]·6H2O （ox = oxalate）, which was characterized by sin...Routine solution reaction of Gd3＋ and p-phenylenediamine-N,N,N′,N′-tetraacetic acid （p-PhDTA） yields a dinuclear complex [Gd2（ox）（p-PhDTA）2（H2O）10]·6H2O （ox = oxalate）, which was characterized by single-crystal X-ray diffraction （MoKα radiation, = 0.71073）, elemental analysis and IR. This complex crystallizes in the monoclinic system, space group P21/n with a = 10.2522（8）, b = 10.0053（8）, c = 23.8834（18）, = 99.1080（10）°, V = 2419.0（3）3, Z = 2, Mr = 1367.32, Dc = 1.877 g/cm3, F（000） = 1368, = 2.830 mm-1, the final R = 0.0337 and wR = 0.0794 for 4747 observed reflections （I 〉 2 （I））. The exo-tetradentate oxalate ligand, generated in situ from the oxidative coupling of methanol, is incorporated to construct a dinuclear Gd2（ox）2 unit decorated with p-PhDTA ligands on the two sides with a monodentate coordination mode. The dinuclear molecules are further connected by the lattice water molecules to form a three-dimen- sional hydrogen network.展开更多
High performance Fe-Gd-P tri-doped TiO2 nanoparticles （1 at% for each dopant） were successfully synthesized by a modified sol-gel method. Various analytical and spectroscopic techniques were carried out to determine...High performance Fe-Gd-P tri-doped TiO2 nanoparticles （1 at% for each dopant） were successfully synthesized by a modified sol-gel method. Various analytical and spectroscopic techniques were carried out to determine the physicochemical properties of the prepared samples, including XRD, EDX, FESEM, BET, FFIR, XPS, PL, EIS and UV-Vis diffuse reflectance spectroscopy. The photocatalytic activities of prepared samples were evaluated by photo degradation of methyl orange （MO） and 4-chlorophenol （4- CP） as model pollutants under visible light irradiation. Effects of each dopant on different properties of TiO2 nanoparticles were investigated. Results show that Gd and P doping enhances Ti02 surface textural properties by forming Ti O Gd and Ti-O-P bonds. It is found that Gd plays a superior role in increasing oxygen vacancies and organic species on TiO2 surface. Gd doping also facilitates transferring of the photo-induced charge carriers to the surface adsorbed species. The enhanced electronic band structure and visible light response, as well as high electron lifetime of Fe-Gd-P tri-doped sample is mainly attributed to Fe and Gd doping. The tri-doped TiO2 with rate constant ofkapp - 1.28 ~ 10-2 min-1 for MO and kapp ~ 0.94 ~ 10-2 min-1 for 4-CP, shows the highest photodegradation rate among all samples including undoped and single doped samples. The improved photocatalytic performance of Fe-Gd-P tri- doped Ti02 is due to the synergistic effect of enhanced surface chemistry and textural properties, increased number of surface adsorbed hydroxyl groups and organic species, improved visible light ab- sorption, increased lifetime of the photo-induced electron/hole pairs and boosted interfacial charge transfer.展开更多
Two long-chain multidentate ligands： 2,9-di-（n-2＇,5＇,8＇-triazanonyl）-1,10-phenanthroline （L^1） and 2,9-di- （n-4＇,7＇,10＇-triazaundecyl）-1,10-phenanthroline （L^2） were synthesized. The hydrolytic kinetics...Two long-chain multidentate ligands： 2,9-di-（n-2＇,5＇,8＇-triazanonyl）-1,10-phenanthroline （L^1） and 2,9-di- （n-4＇,7＇,10＇-triazaundecyl）-1,10-phenanthroline （L^2） were synthesized. The hydrolytic kinetics of 2-hydroxypropyl p-nitrophenyl phosphate （HPNP） catalyzed by the complexes of L^1 or L^2 with La（Ⅲ） or Gd（Ⅲ） have been studied in aqueous solution at （298.2±0.1） K, I=0.10 mol·dm^-3 KNO3 in pH 7.5-9.1, respectively, finding that the catalytic effect of GdL^1 was the best among the four complexes for hydrolysis of HPNP. Its kLnLH-1, kLnLand pKa are 0.047 mol^-1·L·s^-1, 0.000074 mol^-1·L·s^-1 and 8.90, respectively. This paper expounded the studied result with the structure of the ligands and the properties of the metal ions, and deduced the catalysis mechanism.展开更多
基金supported by the Program for New Material Development & Application innovative Research Team of Higher Education in Chong Qing of China (Grant No. 201042)
文摘A series of(Y_(1-y), Gdy)_(0.95-x)(P_y, V_(1-y))O_4 :0.05Eu^(3+), xBi^(3+)+phosphors have been successfully prepared by a subsection method. The crystal structure, surface morphology and luminescence properties were investigated. It was found that the sintered samples crystallized in a tetragonal crystal system with space group I_(41)/amd(a = b = 0.7119 nm, c = 0.6290 nm). The products presented rod-like morphology with length of 100-150 nm and width of 50-100 nm. A maximum peak at 619 nm(~5D_0 →~7F_2) was observed in emission spectrum of the phosphors. It was also found that co-doping of Bi^(3+)+, P5+and Gd^(3+)ions into YVO_4:Eu^(3+)can not only made the right edge of the excitation band shift to the long-wavelength region, but also increased the emission intensity at 619 nm sharply and decreased the lifetime of fluorescence decay. These results may expand the application scope of the phosphors.
基金Supported by Innovative Research Institute for Cell Therapy,Ministry for Health,Welfare and Family Affairs(A062260)in South Korea
文摘AIM: To investigate the performance of Gadofluorine P-enhanced magnetic resonance imaging(MRI) on the diagnosis of diabetes in a streptozotocin(STZ)-induced diabetic rat model.METHODS: Fischer 344 rats were treated with STZ.Rats not treated with STZ served as controls. T1-weighted MRI was performed using a 3T scanner before and after the injection of Gd-DOTA or Gadofluorine P(6 diabetic rats, 5 controls). The normalized signal intensity(SI) and the enhancement ratio(ER) of the pancreas were measured at each time point, and the values were compared between the normal and diabetic rats using the Mann-Whitney test. In addition,the values were correlated with the mean islet number.Optimal cut-off values were calculated using a positive test based on receiver operating characteristics.Intrapancreatic Gd concentration after the injection of each contrast media was measured using laser ablation-inductively coupled plasma-mass spectrometry in a separate set of rats(4 diabetic rats, 4 controls for Gadofluorine P; 2, 2 for Gd-DOTA).RESULTS: The normalized SI and ER of the pancreas using Gd-DOTA were not significantly different between diabetic rats and controls. With Gadofluorine P, the values were significantly higher in the diabetic rats than in the control rats 30 min after injection(P < 0.05). The area under the receiver operating characteristic curve that differentiated diabetic rats from the control group was greater for Gadofluorine P than for Gd-DOTA(0.967 vs 0.667, P = 0.085). An increase in normalized SI 30 min after Gadofluorine P was correlated with a decrease in the mean number of islets(r 2 = 0.510, P = 0.014). Intra-pancreatic Gd was higher in rats with Gadofluorine P injection than Gd-DOTA injection(Gadofluorine P vs Gd-DOTA, 7.37 vs 0.00, P < 0.01). A significant difference in the concentration of intrapancreatic Gd was observed between the control and diabetic animals that were sacrificed 30 min after Gadofluorine P injection(control vs diabetic, 3.25 ng/g vs 10.55 ng/g, P < 0.05)CONCLUSION: In this STZ-induced diabetes rat model,Gadofluorine P-enhanced MRI of the pancreas showed high accuracy in the diagnosis of diabetes.
基金the National Natural Science Foundation of China (No. 21001030 and 21101032)the Foundation for the Authors of Excellent Doctoral Dissertation of Guangdong Province (No. sybzzxm201048)the "211" Creative Project of Guangdong Province
文摘Routine solution reaction of Gd3＋ and p-phenylenediamine-N,N,N′,N′-tetraacetic acid （p-PhDTA） yields a dinuclear complex [Gd2（ox）（p-PhDTA）2（H2O）10]·6H2O （ox = oxalate）, which was characterized by single-crystal X-ray diffraction （MoKα radiation, = 0.71073）, elemental analysis and IR. This complex crystallizes in the monoclinic system, space group P21/n with a = 10.2522（8）, b = 10.0053（8）, c = 23.8834（18）, = 99.1080（10）°, V = 2419.0（3）3, Z = 2, Mr = 1367.32, Dc = 1.877 g/cm3, F（000） = 1368, = 2.830 mm-1, the final R = 0.0337 and wR = 0.0794 for 4747 observed reflections （I 〉 2 （I））. The exo-tetradentate oxalate ligand, generated in situ from the oxidative coupling of methanol, is incorporated to construct a dinuclear Gd2（ox）2 unit decorated with p-PhDTA ligands on the two sides with a monodentate coordination mode. The dinuclear molecules are further connected by the lattice water molecules to form a three-dimen- sional hydrogen network.
基金Project supported by the Research office of the Sharif University of Technology(90212681)
文摘High performance Fe-Gd-P tri-doped TiO2 nanoparticles （1 at% for each dopant） were successfully synthesized by a modified sol-gel method. Various analytical and spectroscopic techniques were carried out to determine the physicochemical properties of the prepared samples, including XRD, EDX, FESEM, BET, FFIR, XPS, PL, EIS and UV-Vis diffuse reflectance spectroscopy. The photocatalytic activities of prepared samples were evaluated by photo degradation of methyl orange （MO） and 4-chlorophenol （4- CP） as model pollutants under visible light irradiation. Effects of each dopant on different properties of TiO2 nanoparticles were investigated. Results show that Gd and P doping enhances Ti02 surface textural properties by forming Ti O Gd and Ti-O-P bonds. It is found that Gd plays a superior role in increasing oxygen vacancies and organic species on TiO2 surface. Gd doping also facilitates transferring of the photo-induced charge carriers to the surface adsorbed species. The enhanced electronic band structure and visible light response, as well as high electron lifetime of Fe-Gd-P tri-doped sample is mainly attributed to Fe and Gd doping. The tri-doped TiO2 with rate constant ofkapp - 1.28 ~ 10-2 min-1 for MO and kapp ~ 0.94 ~ 10-2 min-1 for 4-CP, shows the highest photodegradation rate among all samples including undoped and single doped samples. The improved photocatalytic performance of Fe-Gd-P tri- doped Ti02 is due to the synergistic effect of enhanced surface chemistry and textural properties, increased number of surface adsorbed hydroxyl groups and organic species, improved visible light ab- sorption, increased lifetime of the photo-induced electron/hole pairs and boosted interfacial charge transfer.
基金Project supported by the National Natural Science Foundation of China （Nos. 20371028, 20671052）.
文摘Two long-chain multidentate ligands： 2,9-di-（n-2＇,5＇,8＇-triazanonyl）-1,10-phenanthroline （L^1） and 2,9-di- （n-4＇,7＇,10＇-triazaundecyl）-1,10-phenanthroline （L^2） were synthesized. The hydrolytic kinetics of 2-hydroxypropyl p-nitrophenyl phosphate （HPNP） catalyzed by the complexes of L^1 or L^2 with La（Ⅲ） or Gd（Ⅲ） have been studied in aqueous solution at （298.2±0.1） K, I=0.10 mol·dm^-3 KNO3 in pH 7.5-9.1, respectively, finding that the catalytic effect of GdL^1 was the best among the four complexes for hydrolysis of HPNP. Its kLnLH-1, kLnLand pKa are 0.047 mol^-1·L·s^-1, 0.000074 mol^-1·L·s^-1 and 8.90, respectively. This paper expounded the studied result with the structure of the ligands and the properties of the metal ions, and deduced the catalysis mechanism.
