Association of polymorphisms of Nramp1 gene with immune function and production performance of large white pig

The present research was designed to study the association of polymorphism of natural resistance-associated macrophage proteinl （Nrampl） with some immune function and the production performance in Large White pig. The PCR-RFLP technique was applied to analyze the correlation between the polymorphisms of Nrampl gene and immune function [value of Polymorphonuclear Leukocytes （PMN） obtained by Nitroblue Tetrazolium （NBT） Reduction and effect of Cytotoxin in Monocyte] and production performance in 165 Large White pigs. The results showed that there was one Nde I restriction locus in Large White pig, and both values of PMN by NBT Reduction and effect of Cytotoxin in Monocyte in genotype BB were higher than those in genotype AB （P〈0.05）. Simultaneously, the weight of 180-day-old pigs with genotype BB was higher than that with genotype AB （P〈0.05）. The results indicated that there was a significant correlation between different genotypes of Nrampl gene and Immune function and production performance, and it can be regarded as a candidate gene of disease resistance. All these results provide valuable reference to further studies of pig disease resistance.

Form Gene Clustering Method about Pan-Ethnic-Group Products Based on Emotional Semantic

The use of pan-ethnic-group products form knowledge primarily depends on a designer＇s subjective experience without user participation. The majority of studies primarily focus on the detection of the perceptual demands of consumers from the target product category. A pan-ethnic-group products form gene clustering method based on emotional semantic is constructed. Consumers＇ perceptual images of the pan-ethnic-group products are obtained by means of product form gene extraction and coding and computer aided product form clustering technology. A case of form gene clustering about the typical pan-ethnic-group products is investigated which indicates that the method is feasible. This paper opens up a new direction for the future development of product form design which improves the agility of product design process in the era of Industry 4.0.

Association of vascular endothelial growth factor-634G/C and receptor for advanced glycation end products G82S gene polymorphisms with diabetic retinopathy

AIMTo investigate the association of receptor for advanced glycation end products (RAGE) G82S and vascular endothelial growth factor (VEGF) -634 G/C gene polymorphisms with diabetic retinopathy (DR).METHODSOur cross-sectional study included 61 diabetic patients, 12 of them had proliferative diabetic retinopathy (PDR), 15 had non proliferative diabetic retinopathy (NPDR), 34 had no diabetic retinopathy (NDR) and 61 healthy controls. Participants were tested for RAGE G82S and VEGF -634 G/C polymorphisms by polymerase chain reaction-restriction fragment length polymorphism.RESULTSWe found a significant association between VEGF -634 G/C polymorphism and PDR as PDR patients had increased incidence of VEGF -634 CC genotype compared to NDR patients [odds ratio for CC vs (GC+GG)=6.5, 95% CI=1.5-27.8, P=0.021]. Also VEGF -634 CC genotype and C allele were significantly higher in the PDR than in NPDR patients, which is a novel finding in our study (P=0.024, 0.009 respectively). The mean triglycerides level was significantly higher in diabetic patients with CC genotype (P=0.01) as compared to patients with other genotypes. All cases and control subjects were of the same heterozygous RAGE 82G/S genotype.CONCLUSIONPatients carrying VEGF -634 C polymorphism have a higher risk of PDR development, so VEGF -634 G/C polymorphism could be used as a predictive marker for PDR in diabetic patients. We could not find a significant association between RAGE G82S polymorphism and DR.

nodD GENE PRODUCT AND THE nodA-D INTERGENIC REGION CAN FORM AS MANY AS SEVEN COMPLEXES

Nodulation is crucial for the symbiosis between Rhizobia and plants, and 13 nod genes have been identified in Rhizobium leguminosarum biovar (bv.) viciae, which are responsible for the formation of nodules on plant roots. The nodD, one of those nod genes, is an autoregulatory gene, which controls the expressions of all the rest nod genes in the

Production Systems, Genetic Diversity and Genes Associated with Prolificacy and Milk Production in Indigenous Goats of Sub-Saharan Africa: A Review

Goats are one of the oldest domesticated animal species widely distributed in the world playing an important role in the food production system in Sub-Saharan African Region (SSAR). Due to their multiple uses (milk production, meat, fiber and hides) and adaptation aptitudes to ecological conditions, goats produce and contribute positively to farmers’ socio-economy status in various production systems. This review aimed at giving a summary overview on the goat’s production systems characteristics, the genetic diversity and the candidate genes affecting reproductive and milk production performances in goat breeds in SSAR. It has been observed that traditional livestock production system with communal grazing system is the most used in goat keeping in SSAR. The geographical locations play an important role in the relationships between goat’s distributions in the region. At the same time, goats might have been differentiated and isolated one to others due to the wide geographic range, the diversify climate and the topography in the region. Among the six worldwide known haplogroups of goat (A, B, C, D, G and F), haplogroup A is the most representative in SSAR. However, haplogroup G and B can be found in some goat populations in some countries in east (Kenya and Ethiopia) and south parts of Africa. This review reveals that little is known on the candidate genes associated with prolificacy and milk production traits in indigenous goat breeds in the region. That observation suggests the importance of assessing candidate genes associated with economic traits in the populations of goat in SSAR.

Product of the Schistosoma mansoni Glutathione Peroxidase Gene is a Selenium ContainingPhospholipid Hydroperoxide Glutathione Peroxidase (PHGPx) Sharing MolecularWeight and Substrate Specificity WithIts Mammalian Counterpart

In the blood fluke Schistosoma mansoni a functionally active, monomeric, phospholipid hydroperoxide glutathione peroxidase (PHGPx) has been purified and characterized. This enzyme contains a catalytically active selenocysteine. The protein has been shown to be the product of a cloned gene, previously referred to as a glutathione peroxidase gene. S. mansoni PHGPx has been found 5 times more abundant in female than in male worm extract. As in vertebrate PHGPx, homology alignment indicates that the residues involved in the glutathione binding by the tetrameric cellular glutathione peroxidase are mutated in the S. mansoni enzyme. Thus, this aspect appears a landmark of the PHGPx-type of glutathione peroxidases,which might be of functional relevance

Correlation between DRD2 Gene Polymorphism and Early Egg Production Performance of Libo Yaoshan Chicken

To improve egg production performance of local chicken breed in Guizhou Province, Libo Yaoshan chicken, with dopamine receptor 2 （ DRD2 ） as one of the candidate genes, we detected its genetic variation in 196 Libe Yaoshan hens using PCR-SSCP （single-strand conformation polymorphism） and sequencing method, and analyzed the correlation between genetic variation and egg production traits. The results showed that TT and TG genotypes in mRNA SNlX）62 （C→T） loci of the DRD2 gene had extremely significant difference in egg production at 38 weeks age （P 〈0.01 ）, and significant difference in egg weight at 300 days age （P 〈0.05 ）. The single nucleotide polymorphisms （SNPs） mutation induced synonymous mutation of the 312th amino acids （leucine） in DRD2 protein, from L （CTG） to L （TI＇G）. The mRNA SNP962 （C→T） loci had a larger genetic effect on egg production at 38 weeks age, and could be used as a molecular marker in early breeding of Libo Yaoshan chicken.

Beta-nerve growth factor promotes neurogenesis and angiogenesis during the repair of bone defects

We previously showed that the repair of bone defects is regulated by neural and vascular signals. In the present study, we examined the effect of topically applied β-nerve growth factor（β-NGF） on neurogenesis and angiogenesis in critical-sized bone defects filled with collagen bone substitute. We created two symmetrical defects, 2.5 mm in diameter, on either side of the parietal bone of the skull, and filled them with bone substitute. Subcutaneously implanted osmotic pumps were used to infuse 10 μgβ-NGF in PBS（β-NGF ＋ PBS） into the right-hand side defect, and PBS into the left（control） defect, over the 7 days following surgery. Immunohistochemical staining and hematoxylin-eosin staining were carried out at 3, 7, 14, 21 and 28 days postoperatively. On day 7, expression of β III-tubulin was lower on the β-NGF ＋ PBS side than on the control side, and that of neurofilament 160 was greater. On day 14, β III-tubulin and protein gene product 9.5 were greater on the β-NGF ＋ PBS side than on the control side. Vascular endothelial growth factor expression was greater on the experimental side than the control side at 7 days, and vascular endothelial growth factor receptor 2 expression was elevated on days 14 and 21, but lower than control levels on day 28. However, no difference in the number of blood vessels was observed between sides. Our results indicate that topical application of β-NGF promoted neurogenesis, and may modulate angiogenesis by promoting nerve regeneration in collagen bone substitute-filled defects.

P53 Gene Mutation and Expression of MDM2, P53,P16 Protein and their Relationship in Human Glioma

To investigate the effect of P53 protein accumulation and p53 gene mutation in the pathogenesis of glioma and to study the role of MDM2, P53 and P16 protein in glioma formation and progression and their relationship with each other, LSAB immunohistochemical staining method and non-isotopic PCR-SSCP techniques were used to detect the expression of MDM2, P53 and P16 protein and p53 gene mutation in 48 cases of gliomas. The results showed that the positive expression rate of MDM2, P53 and the negative rate of P16 was 22.9 %, 41.7 % and 60.4 %, respectively. The latter two in high grade （grade Ⅲ , Ⅳ） gliomas had a significantly higher rate than in the low grade （grade Ⅱ ） gliomas. Moreover, the co-expression of MDM2 and P53 protein was confirmed in only 1 of 48 cases. No significant difference was found in the rate of the expression of MDM2 between high grade and low grade gliomas （P〉0.1） . PCR-SSCP results showed that mutation of 5 --8 exons of p53 gene was detected in 17 out of 48 cases （35.42 %） . Mutation was detected in 16 of 20 cases of positive p53 expression, and another one was detected in 28 cases of negative expression cases. The correlation between p53 mutation and p53 immunopositivity was observed in 89.6 % of the cases. P53 gene mutation and the level of MDM2, P53 and PI6 protein were not related to age, gender of the patients, tumor location and size. It is concluded that the mutation of p53 and deletion of p16 might play important roles in the tumorigenesis of gliomas and it was significantly associated with the grade of tumor differentiation. P53 protein accumulation can indirectly reflect p53 mutation. MDM2 amplification and overexpression might be an early event in the growth of human gliomas.

The expression of c-src gene in the carcinogenesis process of human cardia adenocarcinoma

AIM To investigate the activation, expression of c src gene and its role in the carcinogenetic process of human cardia adenocarcinoma (CA). METHODS Fifty six cases of CA, 34 cases of normal, 36 cases of protiferative epithelia adjacent to carcinoma, and 20 cases of lymph node metastases of CA were studied for PP60 c src , the expression product of c src gene immunohistochemically by using the specific monoclonal antibody, Mab327. RESULTS The positive rates of PP60 c src in the normal epithelia, protiferative epithelia, CA and lymph node metastases were 29 4% (10/*!34), 94 4% (34/*!36), 71 4% (40/*!56) and 60 0% (12/*!20) , respectively, among them, the differences of the positive rates were statistically significant ( P <0 01) . The expression levels of PP60 c src in CA and proliferative epithelia were significantly higher than that in the normal epithelia ( P <0 01) . The PP60 c src positive rates in the papillary, tubular, poorly differentiated and mucous adenocarcinoma were 75 0% (6/*!8) , 81 8% (18/*!22) , 50 0% (10/*!20) and 100 0% (6/*!6) , respectively, whereas those of tubular and mucous adenocarcinomas were significantly higher than those of papillary and poorly differentiated adenocarcinomas ( P <0 05) , and the PP60 c src expression levels of tubular and mucous adenocarcinomas were also significantly higher than those of papillary and poorly differentiated adenocarcinomas ( P <0 01) . CONCLUSION The activation and expression of c src gene are associated with the initiation and development of human CA; the protein amount of PP60 c src increased during the process of carcinogenesis; and PP60 c src expression is also related to lymph node metastases.

南粳系列超级稻品种灌浆期光合产物的分配特性

【目的】研究南粳系列超级稻灌浆期光合产物转运和分配及相关基因表达量的变化特性及其与对照品种的差异,总结南粳系列超级稻高产的生理优势,为优质高产粳稻的培育提供理论依据。【方法】采用南粳5718、南粳晶谷、南粳3908和南粳5055为研究对象,以淮稻5号为对照,在孕穗期、开花期以及开花后每隔7 d至成熟期测定剑叶光合速率、地上部干物质分配和转运,以及剑叶和籽粒发育不同时期物质转运相关基因的表达量,统计产量差异。【结果】南粳系列超级稻产量和千粒重高于淮稻5号,其剑叶净光合速率在孕穗期和花后28 d显著高于淮稻5号。在物质转运方面,南粳系列超级稻开花后茎叶干重、叶片输出量、输出率和转运率显著高于淮稻5号,其中南粳5718叶片输出量和输出率最高。南粳5718剑叶中与淀粉降解和糖类代谢相关基因(OsSPS1,OsSUT2,OsGWD1)的表达比其他品种启动早,最高表达量也高于其他品种。籽粒中SWEET基因在灌浆早期的蔗糖转运过程中扮演重要角色,中后期OsPK3、OsSUT1、OsSUT2基因在糖类的运输卸载中发挥重要作用,OsAGPL2和OsDPE1基因在中后期淀粉合成中发挥重要作用,南粳5718、南粳晶谷、南粳3908籽粒中与淀粉合成和糖类运输的相关基因在不同时期的表达量显著高于淮稻5号。【结论】南粳系列超级稻较高的产量在物质转运方面主要有以下特征:茎秆和叶片物质积累量多,穗积累量大,叶片和茎秆物质转运率高;叶片中蔗糖代谢和转运相关基因表达量高,有利于蔗糖在源端的合成、装载和转运;籽粒中蔗糖转运和淀粉合成相关基因表达量高,有利于蔗糖在库端的卸载及籽粒中淀粉的合成。

杜撒×大长撒VRTN基因多态及其与生产性状的关联研究

为研究杜撒×大长撒VRTN基因多态及其对育肥、胴体、肉质的影响。采用PCR直接测序法对杜撒×大长撒、杜洛克、长白、大白VRTN基因启动子区和4个外显子区进行单核苷酸多态性检测,计算VRTN基因多态位点基因型频率及基因频率,测定杜撒×大长撒猪群的育肥、胴体和肌肉品质,采用最小二乘模型分析VRTN基因与育肥、胴体、肉质的关联。结果显示:在4个猪群中共检测到VRTN g.97615896_97615897ins291和VRTN g.97622607G>A 2个突变位点具有多态性,其中,g.97615896_97615897ins291在4个猪群中均存在Q/Q、Q/Wt、Wt/Wt 3种基因型,4个群体均属于中度多态,均处于Hardy-Weinberg平衡状态;杜撒×大长撒g.97615896_97615897ins291位点Q/Q基因型活体背膘厚比Wt/Wt基因型少0.36 mm(P<0.05)、肋骨数比Wt/Wt基因型多0.63对(P<0.01),Q/Wt基因型胴体斜长比Wt/Wt长1.56 cm(P<0.05),Q/Q和Q/Wt基因型眼肌面积比Wt/Wt多4.38 cm^(2)、4.34 cm^(2)(P<0.05),Q/Q基因型瘦肉率比Wt/Wt高3.23百分点(P<0.05)、脂率比Wt/Wt低4.1百分点(P<0.05);VRTN g.97622607G>A位点在杜撒×大长撒属于低度多态(PIC=0.0799),处于Hardy-Weinberg平衡状态;杜撒×大长撒VRTN g.97622607G>A位点GG基因型30~100 kg日增重比GA基因型多61.43 g·d^(-1)(P<0.01),瘦肉率比GA基因型高2.53百分点(P<0.05)。结果表明:VRTN g.97615896_97615897ins291位点插入等位基因Q可增加杜撒×大长撒猪群肋骨数、胴体斜长、眼肌面积和瘦肉率,降低活体背膘厚和脂率;VRTN g.97622607G>A位点GG基因型可提高杜撒×大长撒猪群的日增重和瘦肉率。本研究结果为利用VRTN基因进行分子标记辅助选择提高撒坝猪的生产性能提供依据。

OVER-EXPRESSION OF A TRUNCATED TYPE I TGF-P RECEPTOR IN NORMAL DERMAL FIBROBLASTS DECREASES TGF-β1 AUTOPRODUCTION

Objective To determine over-expression of a truncated type ⅡTGF-β receptor in down-regulating TGF-β1 auto production in normal dermal fibroblasts. Methods In vitro cultured dermal fibroblasts were treated with rhTGF-β1 (5ng/ml) or recombinant adenovirus containing α truncated type Ⅱ TGF-β receptor gene (50 pfu/cell). Their effects on regulating gene expression of TGF-β1 were observed with Northern Blot. Results rh TGF-β1 up-regulated the gene expression of TGF-β1, (34 %-150%) and type Ⅰ pro-collagen( 13 %- 190%). Overexpression of a truncated receptor Ⅱ decreased the gene expression of TGF-β1 (53%-66%). Conclusion Over-expression of the truncated TGF-β receptor Ⅱdown-regulated TGF-β1 autoproduction via blocking signal transduction of TGF-β. This study may provide a new strategy for scar gene therapy.

Cloning and characterization of geranylgeranyl diphosphate synthetase from Pinus massoniana and its correlation with resin productivity

Geranylgeranyl pyrophosphate synthetase(GGPPS) has gained increasing attention as a key enzyme in terpene analysis.We designed specific primers based on plant GGPPS homologs and used reverse transcription polymerase chain reaction(RT-PCR) to obtain and identify Pin GGPPS,a GGPPS gene sequence from Pinus massoniana,using bioinformatics tools.Quantitative PCR analysis of Pin GGPPS expression levels in roots,pine needles,immature stems,and semilignified stems from 6-month-old P.massoniana showed that expression levels of Pin GGPPS were highest in pine needles,followed by immature stems and semilignified stems,and lowest in roots.When we examined the correlation between Pin GGPPS gene expression levels and resin productivity in 20 adult plants for 28 successive days,Pin GGPPS expression levels presented a substantially linear distribution when plotted against their corresponding resin yields.In summary,we characterized the gene Pin GGPPS for the first time in P.massoniana,and established a correlation between Pin GGPPS gene expression levels and resin productivity,suggesting the importance of theory and production practice for P.massoniana.

基于眼动追踪的产品族设计基因识别强度研究

目的对小米品牌产品族中多品类的产品设计开展案例研究,探索其设计基因的构成特性,研究分析产品设计基因的识别强度差异性,进而初步形成产品设计基因的提取及构建方法,以及识别强度分析方法。方法首先构建产品设计基因识别强度对比方法,通过卡片分类法、聚类分析法和多维尺度分析法筛选出典型样本;其次由问卷分析和设计形态分析提取典型基因;最后结合眼动追踪和熵权法综合评价基因识别强度差异。结果形成小米品牌产品(家电与智能类)因子库,包含通用型基因5项,专用型基因18项,且通用型基因的识别强度高于专用型基因。结论初步构建了基于眼动追踪的产品族设计基因识别强度研究方法,可以此作为基础规划及管理产品设计方案,使产品设计兼顾品牌基因的延续性及单品设计的合理性;同时还可为生态链企业研发同品牌、不同品类产品提供设计策略与参考。

文化基因视域下区域农产品品牌视觉形象设计

随着国家对乡村振兴事业的进一步扶持,区域农产品品牌化已成为必然趋势。针对现阶段区域农产品品牌视觉形象良莠不齐、同质化严重的现状,探索文化基因视域下区域农产品品牌视觉形象的设计原则与设计策略,旨在通过地域文化赋能品牌的方式打造差异化定位,为其创意设计及其延展提供源源不断的设计动力;层次分析法的介入可以通过为创意设计提供量化依据,来克服传统方案在择优过程中的绝对主观性,从而减少品牌的试错成本。

自抗性基因导向的活性天然产物挖掘

天然产物是医药与农药的重要来源。基因组测序和生物信息学分析技术的飞速发展,揭示了大量功能未知的天然产物生物合成基因簇,利用生物信息学工具,从这些庞大的基因簇数据中挖掘活性天然产物已经成为发现新型天然药物的重要途径。天然产物的生产者们利用自抗性基因所表达的自抗性酶来保护自身,这种自抗性酶是体内一些初级代谢途径中管家酶的变体,不但对于活性天然产物具有较好的耐受性,还可以在生产活性天然产物的同时确保宿主体内代谢的正常进行。因而,自抗性基因指导的天然产物研究有效地将活性导向和基因组导向的天然产物发掘策略桥连起来,为精准发掘具有目标活性的新型天然产物提供了有效策略。本文对利用自抗性基因作为探针进行天然产物发掘的代表性研究工作进行了整理和总结,并对研究趋势进行了展望,主要包括:①对于活性已知的天然产物,利用其自抗性基因来定位生物合成基因簇的研究;②以天然产物生物合成基因簇中的自抗性基因为线索,预测产物的作用靶点的研究;③利用天然产物自抗性机制,将具有已知作用机制的活性分子进行快速排重的研究;④利用自抗性基因与天然产物及其活性的内在联系,以目标靶点导向的活性天然产物基因组挖掘;⑤自抗性基因导向的基因组数据挖掘工具的发展情况。

Comparison of Two Real-time PCR Technigues for Quantification of GMO Contents in Highly Processed Products of Soybean

The RR soybean was quantitatively detected by ABI Prism 7300 sequence detector with PCR primers and fluorescence probes were designed according to the sequences of endogenous Lectin gene and exogenous CP4-EPSPS gene, and the PCR systems were based on SYBR Green I and TaqMan. The standard curve of ACt between CP4-EPSPS gene and Lectin gene of the RR soybean in standard materials was generated and a linear regression equation was obtained. Quantification methods were optimized through two different real-time PCR chemistries, i.e. SYBR Green I and TaqMan, and the RR soybean contents were quantified in five standard samples and seven highly processed products by the two assays. Both methods are proved to be specific, highly sensitive and reliable for both identification and quantification of soybean DNA. The results indicate that the two optimized PCR system can be used for the practical quantitative detection of RR soybean in highly processed products.

深加工益生菌产品中常用7种乳杆菌的快速鉴定

目的探讨适用于复杂基质中益生菌产品的DNA提取方法,并通过鉴定7种常见的乳杆菌,比较产品标签标示与实际添加乳杆菌种类的一致性。方法本研究采用了3种不同的DNA提取方法,分别为十六烷基三甲基溴化铵(cetyltrimethylammonium bromide,CTAB)法、磁珠法深加工产品基因组DNA抽提试剂盒(磁珠法)和Ezup柱式深加工产品基因组DNA抽提试剂盒(柱式法);通过测定DNA浓度、纯度以及利用16SrDNA V3/V4基因扩增技术评估DNA质量。此外合成嗜酸乳杆菌、德氏乳杆菌保加利亚亚种、罗伊氏粘液乳杆菌、植物乳植杆菌、干酪乳酪杆菌、鼠李糖乳酪杆菌和副干酪乳酪杆菌特异性引物探针,利用实时荧光定量聚合酶链式反应(real-time fluorescence quantitative PCR,qPCR)技术验证方法的特异性、灵敏度和重复性,进一步对市售益生菌产品进行乳杆菌种类的鉴定。结果综合3个DNA质量评价方法,使用CTAB法提取的DNA质量较高,纯度在1.7~2.1之间,质量浓度大于25ng/mL,且16SrDNAV3/V4基因扩增的循环数阈值(cycle threshold,Ct)值均小于35,符合后续qPCR扩增要求;相比之下,柱式法除了饼干类产品DNA纯度为1.96±0.13,浓度为79.07±2.15,扩增Ct值为22.67±3.09能够达到要求外,提取的其他产品DNA和磁珠法提取的DNA无法同时满足3个DNA评价方法要求且重复性较差。本研究所使用的引物和探针对目标乳杆菌有明显的特异性扩增,灵敏度范围为0.0100~1.0000ng/μL和10^(3)~10^(4)CFU/mL,且重复性良好[相对标准偏差(relative standard deviation,RSD)≤3.02%]。检测的20批市售产品中,6批产品未检出标示的乳杆菌种类,存在标示与实际检出菌种不符的情况。结论CTAB法因其较高的适应性和低成本,在提取复杂基质中益生菌产品的DNA时表现更优,结合qPCR方法能有效实现产品中乳杆菌种水平鉴定;然而针对干酪乳酪杆菌的检出限需要进一步研究开发更为灵敏的引物和探针。

三生空间视角下传统村落空间基因图谱构建及特征解析——以扎尕那村为例

传统村落三生空间的优化布局有赖于对其空间特征及其内在结构的认识。文章以扎尕那村为例,从三生空间的视角建立空间基因图谱,并以此为基础确定村落三生空间基因特征。研究表明:(1)基于土地利用数据构建三生空间基因描述具有区别于单一空间基因的新维度;(2)运用参数化方法进行空间基因识别提取具有可操作性;(3)借助“三生空间关系”图形及“地理信息要素分类”编码的形式实现空间基因图谱表达可更好服务于国土空间规划;(4)基于空间基因图谱识别出的扎尕那三生空间特征明显,生态空间由9种景观类型组成,裸岩与林地是景观的基质;生活空间建设用地破碎度较高,呈自由式带状布局;生产空间形成农林牧垂直经济类型。