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Perceptions of Mothers with Preterm Babies towards Donor Breast Milk at Women and Newborn Hospital,Lusaka Zambia
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作者 Monde Muyangana Maureen Masumo Mutinke Zulu 《Open Journal of Pediatrics》 2024年第4期669-685,共17页
Breast milk offers essential nutrients crucial for the development of the preterm immune system, thus reducing the incidence of infection and mortality often associated with prematurity. In the absence of breast milk,... Breast milk offers essential nutrients crucial for the development of the preterm immune system, thus reducing the incidence of infection and mortality often associated with prematurity. In the absence of breast milk, the preferred option is donated breast milk, the best alternative for hospitalized neonates whose mothers have insufficient breast milk or are unavailable. In Zambia, donor breast milk is unavailable. Instead, the protocol recommends the administration of formula milk. However, the use of formula milk in preterm babies is associated with an increased risk of necrotizing enterocolitis and sepsis. Zambia needs to establish a donor milk bank, hence the need to understand the perception of mothers towards donated breast milk. A qualitative descriptive case study utilized 10 focus group discussions with in-depth interviews, purposively selected using a variation strategy. Data was thematically analysed. Participants demonstrated potential acceptance to donor breast milk utilization, as more nutritional compared to formula despite lack of awareness. Concerns related to safety, quality, fear of disease transmission and discomfort feeding from a different bloodline were identified as hinderance to possible utilisation. These perceptions underscore the importance of educational initiatives aimed at dispelling myths and misconceptions surrounding donor breast milk and establishing donor breast milk programs. Therefore, the study recommends educational initiatives tailored to raise awareness to mothers about donor breast milk. 展开更多
关键词 Perception Donor Breast Milk Preterm Baby
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Acceptability of Kangaroo Mother Care (KMC) by Mothers with Low-Birth-Weight Babies at Arthur Davison Children’s Hospital, in Ndola, Zambia
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作者 Julia D. Kalito Maureen M. Masumo Chapima Fabian 《Open Journal of Obstetrics and Gynecology》 2024年第5期790-823,共34页
Background: Kangaroo Mother Care is a simple safe method used to care for low-birth-weight babies. Low-birth-weight is a global public health issue that pose significant challenge to perinatal care systems. Globally, ... Background: Kangaroo Mother Care is a simple safe method used to care for low-birth-weight babies. Low-birth-weight is a global public health issue that pose significant challenge to perinatal care systems. Globally, complications due to low-birth-weight are the leading cause of neonatal mortality, resulting in an estimated 1 million deaths annually. Kangaroo Mother Care (KMC) is a low-cost method of care for low-birth-weight infants in areas with inadequate incubators and power outages with positive outcomes. Objectives: To assess factors influencing acceptability of Kangaroo Mother Care (KMC) in NICU at Arthur Davison Children’s Hospital in Ndola, Zambia. Methodology: A cross sectional quantitative analytical study design was used. The study was conducted at Arthur Davison Children’s Hospital (ADCH) in Ndola, Zambia. The purposive sampling method was used to select the study participants and a total of 129 mothers with Low Weight Babies A were selected to participate structured closed ended questionnaire was used to collect data from the participants using an interview. Data was analyzed using a Statistical Package for Social Scientists (SPSS) software version 26. Cross tabulations were done to determine association of variables using a Chi square (x<sup>2</sup>) test at 95% confidence interval and were assumptions where not met, fishers exact test was used. Multivariate binary logistic regression analysis was used to quantify the relationship between the dependent and independent variables. Results: Most of the respondents had male babies 77%, 69% of the babies weighed 1000 g - 1400 g, majority 79% had normal delivery, 71% of the respondents were multigravida and most of the respondents 79% were married. The study reviewed that 85% of those who attained secondary education accepted KMC, 74% of the respondents without monthly income accepted KMC, 80% of the respondents had positive attitude and accepted KMC. 82% of the respondents who had positive perception accepted KMC. Conclusion: Acceptance of Kangaroo Mother Care (KMC) among 75% of the mothers underscores its widespread favourability as a beneficial method for infant care. 展开更多
关键词 ACCEPTABILITY Kangaroo Mother Care Low Birth Weight babies
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Distortion product otoacoustic emissions in newborn babies with and without late-term maternal iron deficiency anaemia
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作者 Deepashree Somanahalli Ramachandra Ajith Kumar Uppunda Kumar Gavali Suryanarayana 《Journal of Otology》 CAS CSCD 2023年第3期132-138,共7页
Background:Studies on animals have demonstrated that maternal iron deficiency anaemia(IDA)could result in decreased cochlear sensory hair cells and reduced amplitudes of distortion-product otoacoustic emissions(DPOAEs... Background:Studies on animals have demonstrated that maternal iron deficiency anaemia(IDA)could result in decreased cochlear sensory hair cells and reduced amplitudes of distortion-product otoacoustic emissions(DPOAEs)of young guinea pigs.Thus,it is essential to study the functioning of cochlear hair cells using DPOAEs in human newborn babies with maternal IDA.The current study explores maternal IDA’s effect on DPOAEs in newborn babies.Method:A total of 110 newborn babies with gestational age≥34 weeks were considered and a‘betweensubjects’design was used.The participants were divided into 3 groups-“Normal”(61 babies without maternal IDA),“Mild”(28 babies with mild maternal IDA)and“Moderate”(21 babies with moderate maternal IDA).The cord blood was collected and the DPOAEs were recorded for each baby for a range of frequencies(1 k 8 kHz)and a range of intensities(7040 dB SPL in 10 dB steps).Results:The analysis of both DP-gram and DP input-output(I/O)function showed that there was no significant difference(p>0.05)across the normal,mild,and moderate groups in the overall presence of DPOAEs as well as the amplitude across frequencies or intensities(7040 dB SPL).Also,the overall correlation of RBC indices with DPOAE amplitude across frequencies as well as the slope of the I/O function showed no relationship.Conclusion:The current study concludes that there is no effect of late-term maternal IDA on the DPOAEs of newborn babies. 展开更多
关键词 Maternal iron deficiency anaemia Newborn babies Distortion product otoacoustic emissions Cochlear hair cell functioning Red blood cell indices HAEMOGLOBIN
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Transfusion related morbidity in premature babies: Possible mechanisms and implications for practice 被引量:5
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作者 Keith James Collard 《World Journal of Clinical Pediatrics》 2014年第3期19-29,共11页
Many premature babies, especially those with a low birth weight are given multiple transfusions during their first few weeks of life. The major serious complications of prematurity include bronchopulmonary dysplasia, ... Many premature babies, especially those with a low birth weight are given multiple transfusions during their first few weeks of life. The major serious complications of prematurity include bronchopulmonary dysplasia, with lesser incidences of retinopathy of prematurity, intraventricular haemorrhage, and necrotising enterocolitis. Many studies have shown correlations between the receipt of blood transfusions and the development of these conditions, but little is known of the underlying pathophysiology of this relationship. Recent studies are beginning to provide some answers. This review examines recent findings with regard to the influence of preparation and storage of paediatric packed red blood cell units on heme, iron, and oxidative status of the units and relates these to the ability of the premature baby to deal with these changes following the receipt of blood transfusions. Paediatric packed red blood cell units are a potential source of heme, redox active iron and free radicals, and this increases with storage age. Haemolysis of transfused red blood cells may add further iron and cell free haemoglobin to the recipient baby. Premature babies, particularly those with low birth weight and gestational age appear to have littlereserve to cope with any additional iron, heme and/or oxidative load. The consequences of these events are discussed with regard to their contribution to the major complications of prematurity and a novel hypothesis regarding transfusion-related morbidity in premature babies is presented. The review concludes with a discussion of potential means of limiting transfusion related iron/heme and oxidative load through the preparation and storage of packed red blood cell units and through modifications in clinical practice. 展开更多
关键词 Blood TRANSFUSIONS PREMATURE babies Iron HEME Oxidative stress Storage lesion Complications of PREMATURITY
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Evaluation of the Babies At Risk Surveillance System in Rushinga District, Mashonaland Central Province, Zimbabwe, 2015
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作者 Alice Kudzaishe Dzvukamanja Cremance Tshuma +4 位作者 Donewell Bangure More Mungati Tsitsi Juru Notion Tafara Gombe Mufuta Tshimanga 《Open Journal of Therapy and Rehabilitation》 2017年第4期148-158,共11页
Background: About 15% of world’s population lives with some disability. Zimbabwe’s prevalence of disability was at 7% in 2013. ARSS is a paper-based system to monitor and detect neuro-developmental conditions and ch... Background: About 15% of world’s population lives with some disability. Zimbabwe’s prevalence of disability was at 7% in 2013. ARSS is a paper-based system to monitor and detect neuro-developmental conditions and childhood disability early. Indicators for registering a baby into ARSS include: low Apgar score, low birth weight and birth asphyxia. Active case finding in Rushinga District in July 2015 identified nine cerebral palsy cases that were missed by the system out of 14 randomly chosen babies delivered at Chimhanda District Hospital. We evaluated the performance of the ARSS in Rushinga District. Methods: We evaluated the system using CDC guidelines for surveillance systems evaluation. All 12 health facilities in Rushinga were included. Health workers involved in ARSS were purposively recruited. Interviewer administered questionnaire, key informant interview guide, checklists and records review were used for data collection. Knowledge of participants on the system was assessed using five-point Likert scale. Data were analyzed using Epi Info 7. Results: Fifty-one participants were recruited for the study. Median years in service for all participants was 7 (Q1 = 6;Q3 = 12). Average knowledge score was 3. Majority participants (82.4%) were not trained on ARSS and cited lack of: knowledge, reporting guidelines, induction and focal persons as reasons for missing AR cases. Currently, ARSS is able to detect only 12.5% of cases. Prevalence of AR babies in Rushinga for period November 2014 to November 2015 was 21.1%. Monthly cost of detecting and registering a case was USD$52.46. Conclusions: ARSS was found to be useful, simple, acceptable and affordable, however was found to be unstable and not sensitive. Training of health workers particularly village health workers and integrating ARSS with the DHIS2 could improve system performance. As a result of the evidence from this evaluation, it has been agreed to include ARSS data on the monthly return form (T5) beginning June 2016. 展开更多
关键词 At Risk babies CEREBRAL PALSY SURVEILLANCE Rushinga DISTRICT
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Maternal and Neonatal Factors Associated with Mortality of Preterm Babies Admitted in Newborn Unit of Kenyatta National Hospital, Kenya
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作者 Angela Mwangi Okubatsion Tekeste Okube Jane Kamau 《Open Journal of Obstetrics and Gynecology》 CAS 2022年第12期1219-1236,共18页
Background: Preterm birth is a primary cause of neonatal morbidity and mortality especially in low-income countries. Although understanding the preventable factors of neonatal deaths in preterm infants is required for... Background: Preterm birth is a primary cause of neonatal morbidity and mortality especially in low-income countries. Although understanding the preventable factors of neonatal deaths in preterm infants is required for timely interventions, data on those factors is lacking in Kenya. We attempted to determine mortality and its associated factors in preterm babies in Kenya. Methods and Materials: A hospital-based, prospective study was implemented from July 2019 to October 2019 involving 163 preterm neonates and their mothers admitted at Kenyatta National Hospital. A systematic random sampling method was used to recruit the study participants. Data on mortality and the associated factors in preterm neonates were collected using a pretested questionnaire for mothers and neonatal medical records. Data was analyzed using descriptive and inferential statistics. Results: The mortality rate was 18.4%. Of the neonates who died, respiratory distress syndrome (63.3%) and neonatal sepsis (20.0%) were documented as the primary causes. Neonates born of single mother (AOR = 8.006, 95% CI 2.267 to 28.272, p = 0.001), unemployed (6.960, 1.059 - 45.757, p = 0.043), self-employed (4.040, 1.067 - 15.302, p = 0.040), anemic (7.465, 2.530 - 22.023, p < 0.001) and with history of bleeding during pregnancy were more likely to have died. The neonates born before 28 weeks of gestation (126.188, 14.554 - 1094.060, p < 0.001), those who did not cry immediately at birth (54.271, 5.970 - 493.395, p < 0.001) and the resuscitated at birth (54.406, 6.807 - 434.851, p < 0.001) were likely to die. Conclusion: High mortality rates of preterm neonates are attributed to both maternal and neonatal factors. Focused antenatal care should aim at early identification of high-risk mothers for early management of bleeding during pregnancy, close monitoring of nutritional status for mothers and health education. 展开更多
关键词 Preterm babies Mortality Rate Factors Associated with Preterm babies Mor-tality
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Assessing gestational age of babies: Performance of obstetric ultrasound scan compared to that from the combination of Naegle’s rule and Dubowitz score in the 21st century
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作者 Baba Usman Ahmadu 《Natural Science》 2013年第8期32-35,共4页
Background: Some researchers have suggested that when Naegle’s rule (NR) and Dubowitz score (DS) are combined, it could out-perform obstetric ultrasound scan (USS). Others still believe that obstetric USS alone is st... Background: Some researchers have suggested that when Naegle’s rule (NR) and Dubowitz score (DS) are combined, it could out-perform obstetric ultrasound scan (USS). Others still believe that obstetric USS alone is still effective relative to the combination of NR rule and DS in assessing the gestational age (GA) of babies. Objectives: To determine and compare the GA of babies using obstetric USS, NR and DS;and to provide relevant public health information on obstetric USS in the 21st century. Methods: Subjects were selected using systematic random sampling and the GA of babies was determined using obstetric USS, NR, and DS. Statistical package for social science (SPSS) statistical software version 16, Illinois, Chicago USA was used for all data analysis. Results: Eightyfive mother-baby pairs were studied. Forty-four babies (52%) were males and 41 (48%) females. Sixty four (75%) were term with a mean (SD) BW of 3.02 (0.59) at 95%CI (2.89 -?3.14) kg. The overall mean GA of the babies was 38.49 (2.89) at 95%CI (38.14 -?38.85) weeks. The mean GA using obstetric USS, NR and DS were 38.52 (1.98) at 95%CI (38.14 -?38.99), 38.09 (4.13) at 95%CI (37.20-?38.99) and 38.82 (2.02) at 95%CI (38.39 -?39.26), but comparison of these means was not significant (p = 0.256). Combined mean GA by NR and DS was 38.46 (3.26) at 95%CI (37.96 -?38.95). Comparing this mean with mean GA obtained by obstetric USS was also not significant (p = 0.885). Conclusion: The GA assessments by Obstetric USS, NR and DS were all reliable, and Obstetric USS performed effectively relative to combined NR and DS. 展开更多
关键词 GESTATIONAL Age babies OBSTETRIC Ultrasound SCAN Naegle’s RULE Dubowitz SCORE Maiduguri NIGERIA
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Automated Speech Recognition System to Detect Babies’ Feelings through Feature Analysis
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作者 Sana Yasin Umar Draz +12 位作者 Tariq Ali Kashaf Shahid Amna Abid Rukhsana Bibi Muhammad Irfan Mohammed A.Huneif Sultan A.Almedhesh Seham M.Alqahtani Alqahtani Abdulwahab Mohammed Jamaan Alzahrani Dhafer Batti Alshehri Alshehri Ali Abdullah Saifur Rahman 《Computers, Materials & Continua》 SCIE EI 2022年第11期4349-4367,共19页
Diagnosing a baby’s feelings poses a challenge for both doctors and parents because babies cannot explain their feelings through expression or speech.Understanding the emotions of babies and their associated expressi... Diagnosing a baby’s feelings poses a challenge for both doctors and parents because babies cannot explain their feelings through expression or speech.Understanding the emotions of babies and their associated expressions during different sensations such as hunger,pain,etc.,is a complicated task.In infancy,all communication and feelings are propagated through cryspeech,which is a natural phenomenon.Several clinical methods can be used to diagnose a baby’s diseases,but nonclinical methods of diagnosing a baby’s feelings are lacking.As such,in this study,we aimed to identify babies’feelings and emotions through their cry using a nonclinical method.Changes in the cry sound can be identified using our method and used to assess the baby’s feelings.We considered the frequency of the cries from the energy of the sound.The feelings represented by the infant’s cry are judged to represent certain sensations expressed by the child using the optimal frequency of the recognition of a real-world audio sound.We used machine learning and artificial intelligence to distinguish cry tones in real time through feature analysis.The experimental group consisted of 50%each male and female babies,and we determined the relevancy of the results against different parameters.This application produced real-time results after recognizing a child’s cry sounds.The novelty of our work is that we,for the first time,successfully derived the feelings of young children through the cry-speech of the child,showing promise for end-user applications. 展开更多
关键词 Cry-to-speak machine learning artificial intelligence cry speech detection babies
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Cohesion Analysis inThe Water Babies --Based on Systemic-Functional Grammar
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作者 张汇杰 《海外英语》 2018年第23期234-235,共2页
Under the guidance of Systemic-Functional Grammar(SFG),cohesion is applied to analyze the selected context.Cohesion plays a great role in organizing a whole context and it can be further divided into grammatical cohes... Under the guidance of Systemic-Functional Grammar(SFG),cohesion is applied to analyze the selected context.Cohesion plays a great role in organizing a whole context and it can be further divided into grammatical cohesion and lexical cohesion.Main ideas of cohesion are illustrated and made it for application,which employs British children's literature-The Water Babies as the object.The research method adopted here is mainly quantitative.Through analyzing selected sections,it is obvious that cohesion helps readers understand the contexts better.Besides,the use of cohesion makes the context more precise and compact.For context,the role of cohesion is irreplaceable. 展开更多
关键词 Systemic-Functional GRAMMAR (SFG) COHESION The WATER babies context
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学习邓斯坦婴儿语言课程对产妇可疑抑郁发生率和产妇及其丈夫主观幸福感的影响
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作者 邓月桂 刘家丽 +1 位作者 刘玉洁 葛圆 《广西医学》 CAS 2024年第8期1192-1196,共5页
目的探讨学习邓斯坦婴儿语言(DBL)课程对产妇可疑抑郁发生率、产妇及其丈夫主观幸福感的影响。方法选取229例产妇及其丈夫作为研究对象,随机分为干预组113例和对照组116例。对照组产妇及其丈夫接受常规孕妇课程,干预组产妇及其丈夫在接... 目的探讨学习邓斯坦婴儿语言(DBL)课程对产妇可疑抑郁发生率、产妇及其丈夫主观幸福感的影响。方法选取229例产妇及其丈夫作为研究对象,随机分为干预组113例和对照组116例。对照组产妇及其丈夫接受常规孕妇课程,干预组产妇及其丈夫在接受常规孕妇课程基础上增加学习DBL课程。比较两组产妇在产后42 d和3个月时的可疑抑郁发生情况,以及两组产妇及其丈夫在产后7 d、42 d和3个月时的主观幸福感得分。结果干预组产妇在产后42 d、3个月的可疑抑郁发生率低于对照组(P<0.05)。干预组产妇及其丈夫在产后7 d、42 d、3个月的主观幸福感得分高于对照组,两组主观幸福感得分有随着观察时间延长而升高的趋势,分组与时间有交互效应(P<0.05)。结论产妇及其丈夫学习DBL课程可降低产妇可疑抑郁发生率,并提高产妇及其丈夫主观幸福感,值得推广。 展开更多
关键词 邓斯坦婴儿语言 产妇 丈夫 抑郁 主观幸福感
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分离自母婴粪便及母乳的短双歧杆菌耐药性研究
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作者 钟智 马昕玮 +1 位作者 路镜达 陈永福 《中国乳品工业》 CAS 北大核心 2024年第3期21-24,50,共5页
短双歧杆菌是人体肠道中常见的一种双歧杆菌,因其具有诸多益生特性被广泛关注,但是对其抗生素耐药性方面的研究严重不足。本研究以23株分离自母婴粪便及母乳的短双歧杆菌为研究对象,测定了菌株对14种常见抗生素的耐药性。研究发现,实验... 短双歧杆菌是人体肠道中常见的一种双歧杆菌,因其具有诸多益生特性被广泛关注,但是对其抗生素耐药性方面的研究严重不足。本研究以23株分离自母婴粪便及母乳的短双歧杆菌为研究对象,测定了菌株对14种常见抗生素的耐药性。研究发现,实验菌株对12种抗生素存在不同程度的耐药性,仅对氨苄西林和利奈唑胺敏感。全部实验菌株均对氯霉素、环丙沙星、卡那霉素、四环素、庆大霉素和新霉素具有耐药性。进一步分析发现,分离自L家庭母亲粪便的菌株对利福平、克林霉素和链霉素的耐药率显著高于婴儿粪便和母乳分离株。短双歧杆菌的耐药表型差异较大,即使是分离自同一个家庭和个体的菌株其耐药表型也不相同。研究为短双歧杆菌的安全性评价和应用提供了基础数据。 展开更多
关键词 短双歧杆菌 耐药性 母婴 母乳 安全性
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传统过夜受精与短时受精在继发不孕患者体外受精中的应用效果比较
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作者 吴成亮 苏占营 +2 位作者 江旺航 辜敏 巢时斌 《当代医学》 2024年第5期123-127,共5页
目的探讨传统过夜受精与短时受精在继发不孕患者体外受精中的应用效果。方法回顾性分析2019年1月至2021年10月于九江市妇幼保健院生殖中心因不孕不育进行体外受精-胚胎移植(IVF-ET)助孕的462个周期继发患者的临床资料,根据不同IVF方案... 目的探讨传统过夜受精与短时受精在继发不孕患者体外受精中的应用效果。方法回顾性分析2019年1月至2021年10月于九江市妇幼保健院生殖中心因不孕不育进行体外受精-胚胎移植(IVF-ET)助孕的462个周期继发患者的临床资料,根据不同IVF方案分为短时受精组[239个周期,胞浆内单精子显微注射(ICSI)周期除外]与传统过夜受精组(223个周期,ICSI周期除外)。两组移植周期均为49个周期。比较两组受精情况、两原核(2PN)率、卵裂率、优胚率、囊胚形成率、优质囊胚率、胚胎利用率及临床妊娠率等情况。结果两组MⅡ卵率、0PN率、1PN率、≥3PN率比较差异无统计学意义;传统过夜受精组2PN率高于短时受精组,差异有统计学意义(P<0.05)。两组卵裂率、优胚率、囊胚形成率、优质囊胚率、胚胎利用率、临床妊娠率比较差异无统计学意义;传统过夜受精组受精率高于短时受精组,差异有统计学意义(P<0.05)。结论传统过夜受精可作为继发不孕患者首选受精方式之一,可以提高卵子利用率及受精率,且不影响胚胎发育质量。 展开更多
关键词 继发性不孕 传统过夜受精 短时受精 试管婴儿
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婴儿纸尿裤内贴层非织造布的常规性能检测
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作者 李淑芳 游小荣 熊宗志 《山东纺织科技》 2024年第4期36-39,共4页
婴儿纸尿裤的内贴层直接与婴儿皮肤接触,主要起到将尿液导向芯层的透水作用。织物的布面情况、克重、强力、断裂伸长率、亲水性、透水性都对终端产品性能有着重要的影响,本文通过研究生产需检测的指标、方法及检测标准,积极探索纸尿裤... 婴儿纸尿裤的内贴层直接与婴儿皮肤接触,主要起到将尿液导向芯层的透水作用。织物的布面情况、克重、强力、断裂伸长率、亲水性、透水性都对终端产品性能有着重要的影响,本文通过研究生产需检测的指标、方法及检测标准,积极探索纸尿裤新国标的适用性。 展开更多
关键词 婴儿纸尿裤 内贴层 非织造布
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不同胎龄早产儿凝血功能比较及颅内出血影响因素分析
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作者 肖娜娜 闫学爽 +3 位作者 张彩宁 王丹 陈源 李娅 《中南医学科学杂志》 CAS 2024年第3期446-448,共3页
目的分析不同胎龄早产儿凝血功能及颅内出血影响因素。方法选择500例早产儿纳入早产儿组,根据胎龄分为早期早产儿组和晚期早产儿组;根据是否颅内出血分为出血组和未出血组。同期选择足月健康新生儿250例为对照组。比较各组血浆凝血酶原... 目的分析不同胎龄早产儿凝血功能及颅内出血影响因素。方法选择500例早产儿纳入早产儿组,根据胎龄分为早期早产儿组和晚期早产儿组;根据是否颅内出血分为出血组和未出血组。同期选择足月健康新生儿250例为对照组。比较各组血浆凝血酶原时间(PT)、血浆纤维蛋白原(FIB)、活化部分凝血活酶时间(APTT)、D-二聚体(DD)、颅内出血发生率。采用多因素Logistic回归分析早产儿出现颅内出血的影响因素。结果早期早产儿组、晚期早产儿组PT、APTT、DD、颅内出血发生率高于对照组,FIB低于对照组,且早期早产儿组较晚期早产儿组更为显著(P<0.05)。出血组早产儿5 min Apgar评分、胎龄、出生体质量、FIB低于未出血组,胎内窘迫、PS治疗、机械通气占比、PT、APTT高于未出血组(P<0.05)。胎内窘迫、PS治疗、机械通气占比、PT、APTT、5 min Apgar评分、胎龄、出生体质量、FIB均为颅内出血影响因素(P<0.05)。结论早产儿多出现凝血功能紊乱,其颅内出血的影响因素较多,早期干预有助于降低早产儿颅内出血发生率。 展开更多
关键词 胎龄 早产儿 凝血功能 颅内出血 影响因素
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基于用户体验的母婴类厨具产品创新设计
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作者 彭红 张馨元 《设计》 2024年第4期114-117,共4页
根据后疫情时代发展需求及厨具产品迭代的分析,研究母婴厨具在使用过程中用户的体验,改进现有厨具的设计流程。基于用户体验研究,将社会需求融入母婴类厨具产品设计,从模块划分的背景分析、市场调研、设计实践、产品优化、产品落地5方... 根据后疫情时代发展需求及厨具产品迭代的分析,研究母婴厨具在使用过程中用户的体验,改进现有厨具的设计流程。基于用户体验研究,将社会需求融入母婴类厨具产品设计,从模块划分的背景分析、市场调研、设计实践、产品优化、产品落地5方面入手,分析产品的设计要素、使用场景、功能体验、包装运输等,以此选取适当的造型因子及功能结构。提出后疫情时代母婴厨具产品设计原则,归纳系统的母婴类厨具创新要点。通过这一系列探索研究,发现母婴类厨具发展的可能性,为其创新设计提供了新思路。 展开更多
关键词 后疫情时代 母婴厨具 用户体验 模块化 创新设计
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一种背包式婴儿座椅的设计与仿真
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作者 于仙 《木工机床》 2024年第2期13-16,共4页
随着生活水平的提高,携带婴儿长途旅行的人数逐年增加,出行携带背包及婴儿推车体力消耗较大。文章设计一种背包式婴儿座椅,采用环保塑料PP制造座椅的硬质本体骨架,在骨架外侧安装布面,可作为背包使用;将座椅固定在行李箱上,可作为推车使... 随着生活水平的提高,携带婴儿长途旅行的人数逐年增加,出行携带背包及婴儿推车体力消耗较大。文章设计一种背包式婴儿座椅,采用环保塑料PP制造座椅的硬质本体骨架,在骨架外侧安装布面,可作为背包使用;将座椅固定在行李箱上,可作为推车使用;背板与本体之间安装角度调节机构,座椅可做小床使用。有限元仿真结果表明:齿轮及齿圈的强度能满足使用需求,安全性能较好。 展开更多
关键词 婴儿座椅 背包 角度调节 固定机构
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超声雾化微酸性电解水对采后娃娃菜流通及货架品质的影响 被引量:2
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作者 孟敌 焦贺 +5 位作者 韩颖 赵安琪 王馨渝 李鹏霞 胡花丽 吴朝霞 《食品工业科技》 CAS 北大核心 2024年第4期290-298,共9页
为了探明微酸性电解水(Slightly acidic electrolyzed water,SAEW)对采后娃娃菜货架品质的影响,本文分析了在低温流通(4±1)℃及货架条件(25±1)℃下,不同浓度(0、50、100和150 mg/L)SAEW超声雾化熏蒸处理对娃娃菜采后保鲜效果... 为了探明微酸性电解水(Slightly acidic electrolyzed water,SAEW)对采后娃娃菜货架品质的影响,本文分析了在低温流通(4±1)℃及货架条件(25±1)℃下,不同浓度(0、50、100和150 mg/L)SAEW超声雾化熏蒸处理对娃娃菜采后保鲜效果的影响。结果显示,较对照和其它浓度(50和150 mg/L)SAEW处理相比,100 mg/L SAEW超声雾化熏蒸处理在货架第6和第9 d时显著抑制了娃娃菜丙二醛含量的升高及总硫苷含量的下降(P<0.05)。进一步的流通及货架模拟结果显示,与对照组相比,100 mg/L的SAEW超声雾化熏蒸处理使娃娃菜中的菌落总数降低了17.04%,总硫苷含量提升了30.11%;另外,该处理显著抑制了采后娃娃菜中亚硝酸盐和丙二醛含量的积累(P<0.05),延缓了可溶性糖、可溶性蛋白、总酚、抗坏血酸和异硫氰酸酯含量的下降,提高了黑芥子酶的活性。100 mg/L SAEW超声雾化熏蒸处理不仅能有效抑制流通及货架期间娃娃菜中菌落总数的生长,而且可有效减缓该过程中娃娃菜营养品质的流失,从而提高娃娃菜的保鲜效果。 展开更多
关键词 微酸性电解水 娃娃菜 衰老 品质 亚硝酸盐 流通 货架期
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真空预冷对采后娃娃菜流通及货架品质的影响 被引量:1
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作者 孟敌 焦贺 +4 位作者 赵安琪 韩颖 何雪 李鹏霞 胡花丽 《食品工业科技》 CAS 北大核心 2024年第9期296-308,共13页
为优选娃娃菜真空预冷的处理条件,维持采后娃娃菜的新鲜品质,在分析不同真空预冷终温(0、2和4℃)和不同真空预冷终压(400、600、800和1000 Pa)对采后娃娃菜预冷效果的基础上,进行了二因素三水平的中心复合响应面试验。结果显示,与不经... 为优选娃娃菜真空预冷的处理条件,维持采后娃娃菜的新鲜品质,在分析不同真空预冷终温(0、2和4℃)和不同真空预冷终压(400、600、800和1000 Pa)对采后娃娃菜预冷效果的基础上,进行了二因素三水平的中心复合响应面试验。结果显示,与不经预冷处理的对照和终温0℃的预冷组相比,在终压600 Pa条件下,2~4℃的预冷终温处理可更好地维持采后娃娃菜的外观品质,抑制其呼吸速率和丙二醛(MDA)含量的升高。在终温2℃条件下,与不经预冷处理的对照和终压1000 Pa的预冷组相比,400~800 Pa的预冷终压处理可更好地维持采后娃娃菜的外观品质,抑制其呼吸速率及MDA含量的升高。进一步的中心复合响应面试验结果显示,采后娃娃菜的真空预冷最优条件为终温4.0℃、终压600 Pa,该真空预冷条件不仅可维持采后娃娃菜的较好品质,而且可使活性物质可溶性蛋白、总酚和抗坏血酸的含量分别提高18.78%、18.47%和33.23%。因此,适宜的真空预冷处理是一种极具潜力的商品化处理技术,能有效维持采后娃娃菜在流通及货架期间的良好品质。 展开更多
关键词 真空预冷 娃娃菜 终温 终压 总酚 可溶性蛋白 抗坏血酸 货架期
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锌指蛋白A20在低出生体重儿胎盘组织中的表达及其对滋养细胞炎症的影响
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作者 高丽娜 董燕 +8 位作者 刘小晖 刘小玲 何晓春 张玉芳 张莉 王秀娟 孙俊 高晶 王玥元 《西部医学》 2024年第9期1288-1294,共7页
目的探讨胎盘组织锌指蛋白A20(A20)的表达水平与低出生体重儿(LBW)新生儿体重及胎盘体重的相关性及其在LBW发病机制中的作用。方法选取2021年9月—2022年5月在本院住院分娩的LBW孕妇30例为LBW组,同期健康妊娠分娩的孕妇30例为健康对照组... 目的探讨胎盘组织锌指蛋白A20(A20)的表达水平与低出生体重儿(LBW)新生儿体重及胎盘体重的相关性及其在LBW发病机制中的作用。方法选取2021年9月—2022年5月在本院住院分娩的LBW孕妇30例为LBW组,同期健康妊娠分娩的孕妇30例为健康对照组(NP组);qRT-PCR和Western blot检测两组胎盘组织A20的表达,采用免疫组化检测胎盘组织中A20表达水平;然后分别将A20的表达水平与LBW组新生儿体重及胎盘体重做相关性分析。同时体外培养人源胎盘滋养细胞株(HTR-8/SVneo),分为对照组(NC组)和单纯LPS刺激组(100 ng/mL),转染A20基因腺病毒过表达后,Western blot检测各组胎盘滋养细胞A20蛋白、NF-κB结合蛋白p65、NF-κB亚单位磷酸化p65(p-p65)和TNF-α和IL-1β蛋白的表达,双抗体夹心酶联免疫吸附测定(ELISA)方法检测上清液TNF-α、IL-1β的表达。结果与NP组比较,LBW组年龄、孕周差异无统计学意义(P>0.05),而新生儿体重、胎盘重量、Apgar评分1 min,5 min差异均有统计学意义(P<0.05);A20在LWB组中明显低表达(P<0.01),免疫组化显示A20在LBW组胎盘组织中降低,且与新生儿体重及胎盘重量呈正相关(P<0.05);与NC组比较,单纯LPS刺激组细胞A20蛋白表达降低(P<0.05),而p-p65和TNF-α和IL-1β蛋白表达降低(P<0.05);转染A20基因腺病毒过表达后,A20表达增加(P<0.05),p-p65和TNF-α和IL-1β蛋白表达降低(P<0.05)。结论A20与LBW的发生发展密切相关,其过表达可有效抑制LPS诱导的滋养细胞炎症因子的产生,有望成为预测LWB的分子标记物和治疗靶点。 展开更多
关键词 锌指蛋白A20 低出生体重儿 新生儿 滋养细胞 炎症
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循经抚触联合康复干预在轻度缺氧缺血性脑病新生儿中的应用效果
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作者 邸伟 刘倩倩 +3 位作者 纪庆红 崔晓薇 王磊 王丽辉 《中国医药导报》 CAS 2024年第4期174-177,共4页
目的 探讨循经抚触联合康复干预在轻度缺氧缺血性脑病(HIE)新生儿中的应用效果。方法 选择2020年1月至2022年6月河北省儿童医院收治的96例轻度HIE患儿,根据随机数字表法将其分为对照组和观察组,每组48例。对照组采用常规康复干预,观察... 目的 探讨循经抚触联合康复干预在轻度缺氧缺血性脑病(HIE)新生儿中的应用效果。方法 选择2020年1月至2022年6月河北省儿童医院收治的96例轻度HIE患儿,根据随机数字表法将其分为对照组和观察组,每组48例。对照组采用常规康复干预,观察组在常规康复干预基础上予以循经抚触干预。观察两组干预前、干预6个月后的智能发育及运动功能情况。结果 干预后,两组头围、身长及体重均高于干预前,且观察组高于对照组(P<0.05);干预后,两组智力发育指数评分及精神运动发育指数评分均高于干预前,且观察组高于对照组(P<0.05);干预后,两组Peabody运动发育量表第2版各项评分均高于干预前,且观察组高于对照组(P<0.05)。结论 循经抚触联合康复干预能够促进HIE患儿体格生长发育及智能发育,有助于改善其运动功能。 展开更多
关键词 婴儿抚触 康复护理 缺氧缺血性脑病 生长发育 运动能力 智能
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