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Genotypic Resistance of F_1 Cotton Hybrids by Inoculation with Different Virulent Isolates of the Fungus Verticillium Dahliae Klebahn
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作者 AMANTURDIEV Alisher KIM Robert 《棉花学报》 CSCD 北大核心 2008年第S1期107-,共1页
The plant pathogen Verticillium dahliae causes severe cotton losses in Uzbekistan. To create cotton varieties that are resistant to the more virulent races of V.dahliae we wanted to determine
关键词 Genotypic resistance of F1 Cotton Hybrids by Inoculation with Different Virulent Isolates of the Fungus Verticillium Dahliae Klebahn
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Experimental and clinical research of HIV-1 resistance in three AIDS patients who had experienced multiple regimens
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作者 LU Jun-feng LI Jue +7 位作者 LI Han-ping LIU Si-yang ZHUANG Dao-ming LIU Yong-jian BAO Zuo-yi LI Lin WU Hao LI Jing-yun 《Chinese Medical Journal》 SCIE CAS CSCD 2009年第6期752-754,共3页
Highly active antiretroviral therapy (HAART) for HIV/AIDS has efficiently controlled the progression of the disease, extended life expectancy and decreased HIV/AIDS related morbidity and mortality since the advent o... Highly active antiretroviral therapy (HAART) for HIV/AIDS has efficiently controlled the progression of the disease, extended life expectancy and decreased HIV/AIDS related morbidity and mortality since the advent of HIV protease inhibitors in 1996.1 Recent emergence of HIV resistance has severely affected the efficacy of antiretroviral therapy. The prevalence of HIV resistance has been increasing from the usage of AZT. Studies in US indicated that the prevalence was approximately 50% in patients who had experienced antiretroviral therapy.2 Antiviral regimens based on resistance tests could efficiently decrease viral load, increase CD4 cell counts and significantly improve the efficacy of antiretroviral therapy.3 There are two methods commonly used to test HIV resistance at present: one is genotypic resistance assay which predict HIV resistance based on resistance mutations in the viral genome; the other is a phenotypic resistance assay which directly evaluates HIV resistance through analyzing drug sensitivity in vitro. 展开更多
关键词 human immunodeficiency virus type 1 genotypic resistance phenotypic resistance multi-drug resistance
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