Ambroxol,the cough expectorant with neuroprotective effects

Ambroxol hydrochloride(2-amino-3,5-dibromo-N-methylbenzylamine hydrochloride)has been used as a mucolytic agent in the treatment of respiratory diseases since the late 1970s.Its effects on mucus membranes such as mucus disruption,increased mucus production,and low toxicity profile were addressed in its original German patent in 1966.These first described properties have kept Ambroxol available worldwide and over the counter in the pharmaceutical market to this day.

German Automobile Expert:Cooperation Instead of Tariffs

“Europe has missed this development opportunity because we are short of a long-term vision.”MORE than 40 exhibitors from 15 major vehicle brands around the world,representing the latest cutting-edge technologies and models,gathered at the seventh China International Import Expo(CIIE),which was held in Shanghai from November 5 to 10.

German Überzeugt in China

In this exclusive interview,Michael Schumann,chairman of the Board of the German Federal Association for Economic Development and Foreign Trade,discusses Sino-German trade relations and the“out-of-proportion”debate on Xinjiang.

Management Practices:Shaping Employee Satisfaction and Commitment in Large German Companies

The rapid evolution of the political,economic,and social landscape has generated increased interest in understanding the contextual application of management styles and behaviours toward employees.In this context,organizations must comprehend and assess employee satisfaction to enhance productivity and realize their strategic and economic goals.Therefore,this study aims to investigate the prevailing and significant management behaviours toward employees in large German companies and their impact on employee satisfaction and job commitment.To achieve the research objective,the study will employ a qualitative method to explore management behaviours toward employees.Data were collected through interviews with randomly selected managers from different companies and departments.The study aims to uncover discrepancies or variations in employee expectations regarding management behaviour.The findings will provide a better understanding of the most prevalent and significant management behaviours toward employees in large German companies and their impact on employee satisfaction and job commitment.The results will be valuable to management in adopting suitable leadership styles and improving employee satisfaction,leading to increased productivity and organizational performance.The research will contribute to the existing body of knowledge in the field of management and human resource management by providing insights into the impact of management behaviours on employees.It will also offer recommendations to management on how to enhance employee satisfaction and job commitment,leading to improved organizational performance.In conclusion,this study will investigate the prevailing management behaviours toward employees in large German companies and their impact on employee satisfaction and job commitment.

德国成人教育研究院的研究主题与机构评估

一、机构概况 成立于1957年的德国成人教育研究院暨莱布尼茨终身学习研究中心（German Institute for Adult Education-Leibniz Centre for Lifelong Learning,DIE）,是一家专门从事继续教育理论和实践研究的机构（见图1）。该机构为应用性研究提供数据和信息,为实践部门提供服务,开发富有创新性的方案。

英德政府推动两国文化交流

据英国教育部网站2017年7月19日消息,英国外交大臣鲍里斯·约翰逊（Boris Johnson）和德国外交部长西格玛尔·加布里尔（Sigmar Gabriel）宣布为＂英德联盟＂（UK-German Connection,UKGC）提供23万英镑,从而促进英国更多的年轻人学习德国的语言与文化,这也意味着两国政府支持本国儿童和教师了解彼此的语言、历史和文化。

印度洋海啸预警系统10年发展概况

2004年12月26日,印度洋海啸导致25万人丧生,500万人需要紧急援助,180万居民无家可归。这场自然灾害给广大地区带来了毁灭性灾难,以及随之而来的悲痛和焦虑,特别是对印尼、泰国和斯里兰卡的影响超出了想象,而这主要是由于当时缺少对整个印度洋地区的预警设备和灾难管理计划。灾难过后,德国和国际社会立即表示支持。

W-Cu合金物理性能模型及理论值计算

本文对不同成分(10 wt.%～50 wt.%Cu)钨铜合金现有的组织结构模型和理论物理性能参数计算模型进行了归纳总结,在此基础上推导了不同模型下的主要物理性能参数的理论值(包括密度,热容,热导率,电导率,热膨胀系数等)。根据不同模型(体积混合物模型,German互联结构模型,Gasik微观力学模型)的特点进行了分析和比较,讨论了不同模型的适用范围,选取得到了不同成分钨铜合金的物理性能参数理论值,并与实验结果进行了比较,为钨铜合金的成分和性能设计与控制提供了初步的理论依据。

略谈医学缩略语的查找

医学缩略语的最初出现,主要是为了满足医务员人记载病历的需要。因为记载病历的文字必须简单明了、准确无误,同时又能重复使用,以节省医务人员的时间。随着现代医学科学的迅速发展,新的疾病的发生。

Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: Epidemiological changes in Germany

AIM:To study the epidemiologic changes of gastroenteropancreatic neuroendocrine tumors(GEP-NET)in Germany,we analyzed two time periods 1976-1988 and1998-2006.METHODS:We evaluated epidemiological data of GEP-NET from the former East German National Cancer Registry(DDR Krebsregister,1976-1988)and its successor,the Joint Cancer Registry(GKR,1998-2006),which was founded after German reunification.Due to a particularly substantial database the epidemiological data from the federal states of Mecklenburg-Western Pomerania,Saxony,Brandenburg and Thuringia,covering a population of more than 10.8 million people,were analyzed.Survival probabilities were calculated using life table analysis.In addition,GEP-NET patients were evaluated for one or more second(non-GEP-NET)primary malignancies.RESULTS:A total of 2821 GEP neuroendocrine neoplasms were identified in the two registries.The overall incidence increased significantly between 1976 and2006 from 0.31(per 100.000 inhabitants per year)to2.27 for men and from 0.57 to 2.38 for women.In the later period studied(2004-2006),the small intestine was the most common site.Neuroendocrine(NE)neoplasms of the small intestine showed the largest absolute increase in incidence,while rectal NE neoplasms exhibited the greatest relative increase.Only the incidence of appendiceal NET in women showed little change between 1976 and 2006.Overall survival of patients varied for sex,tumor site and the two periods studied but improved significantly over time.Interestingly,about 20%of the GEP-NET patients developed one or more second malignancies.Their most common location was the gastrointestinal tract.GEP-NET patients without second malignancies fared better than those with one or more of them.CONCLUSION:The number of detected GEP-NET increased about 5-fold in Germany between 1976 and2006.At the same time,their anatomic distribution changed,and the survival of GEP-NET patients improved significantly.Second malignancies are common and influence the overall survival of GEP-NET patients.Thus,GEP-NET warrant our attention as well as intensive research on their tumorigenesis.

Habitat influences on diversity of bacteria found on German cockroach in Beijing

Cockroaches are worldwide indoor pests carrying microorganisms of medical importance. German cockroaches （Blattella germanica） were sampled in five habitats （hospital, restaurant, office home, and market） in Beijing, and the bacteria were isolated from their external surface and alimentary tract and identified using a Biolog identification system. Cockroach densities significantly differed among habitats （market 〉 home 〉 office 〉 restaurant 〉 hospital）. However, no significant differences in bacterial abundance carried by individual German cockroaches （of either sex） were found among habitats. The bacterial abundance in the gut was significantly higher than that on the surface. There were no significant differences in bacterial species richness observed among habitats, sex, carrying position or their interaction. Cluster analysis showed that cockroach densities and bacterial abundance found in the market differed significantly from the other four habitats. The bacterial diversity was not significantly reduced in sensitive facilities such as hospital and restaurant, even though pesticide and bactericide were more frequently applied there. The implications of these findings were discussed in this article.

Evaluation of proline, chlorophyll, soluble sugar content and uptake of nutrients in the German chamomile (Matricaria chamomilla L.) under drought stress and organic fertilizer treatments

Objective: To investigate the effect of drought stress and organic fertilizer on German chamomile(Matricaria chamomilla) nutrient uptake, leaf chlorophyll content and osmotic adjustment under field conditions.Methods: This experiment was carried out through a randomized complete block design with a split factorial arrangement of treatments in three replications. The main plots were subjected to the following irrigation treatments: irrigation after 60, 90, 120, 150 and180 mm evaporation from Class A pan. The sub-plots were treated with three vermicompost doses(0, 5 and 10 t/ha).Results: Although drought stress reduced the nutrient percentages in the shoots, application of vermicompost enhanced the nutrient percentages, particularly when the plants were subjected to moderate to severe drought stress conditions. Moreover, the results of this study showed that the interaction between irrigation treatments and vermicompost rates on leaf chlorophyll content was significant. Comparison between the combined treatments indicated that under normal irrigation and moderate drought stress conditions chamomile plants received 5 and 10 t/ha vermicompost showed significantly higher leaf chlorophyll content comparing to the control treatment.Conclusions: Totally, organic fertilization by vermicompost could partly alleviate the effect of drought stress on chamomile by increasing N, P and K uptake and leaf soluble sugar, especially in stressed treatments.

Artificial intelligence in ophthalmology

Immediate Past President of International Council of Ophthalmology(ICO);Academician and former Secretary General of Academia Ophthalmologica Internationalis(AOI);Former Chairman of the Scientific Program of the World Congress of Ophthalmology(WOC);Member of the German Academy of Sciences,former President of German Society of Ophthalmology(DOG);Former Executive Vice President of University of Leipzig and Director of the Eye Hospital;Member of the Club Jules Gonin Executive Committee(2000-2006)。

A Single-Frequency Linearly Polarized Fiber Laser Using a Newly Developed Heavily Tm3+-Doped Germanate Glass Fiber at 1.95 μm

A compact linearly polarized, low-noise, narrow-linewidth, single-frequency fiber laser at 1950nm is demonstrated. This compact fiber laser is based on a 21-mm-long homemade Tm3＋-doped germanate glass fiber. Over 100-mW stable continuous-wave single transverse and longitudinal mode lasing at 195Ohm are achieved. The measured relative intensity noise is less than -135dB/Hz at frequencies over 5 MHz. The signal-to-noise ratio of the laser is larger than 72dB, and the laser linewidth is less than 6kHz, while the obtained linear polarization extinction ratio is higher than 22 dB.

Bubble Generation in Germanate Glass Induced by Femtosecond Laser

We report the observation of bubble generation and migration in a germanate g/ass during irradiation by a femtosecond laser of high repetition rate. Bubbles are formed around the focal area of the laser beam, and their movement indicates the presence of thermal gravity convection in the glass melt, which is beyond the existing theoretical model about temperature l^eld of focal area. Inside the bubbles, oxygen molecules are observed by the con focal Raman micro-spectroscopy. The generation of molecular oxygen and bubbles is explained in terms of the spatial separation of Ge and 0 ions and micro-explosion inside the glass melt.

Gain properties of germanate glasses singly doped with Tm^(3+) and Ho^(3+) ions

Two kinds of germanate glasses singly doped with the ion concentration of 2.0mol.%Tm3＋ and 2.0mol.%Ho3＋, respectively, were prepared.According to McCumber theory, the absorption and stimulated emission cross-sections corresponding to the 3H6←→3F4 transitions of Tm3＋（at 1.8 μm） and the 5I8←→5I7 transitions of Ho3＋（at 2.0 μm） were obtained, and respective gain cross-section spectra were also computed as a function of population inversion according to absorption and emission cross-sections and the ion concentrations.For Tm3＋-doped germanate glasses, the maximum of the absorption, emission, and gain cross-sections reached a value higher than those reported for fluorozirconate, fluoride, and oxyfluoride glasses.For Ho3＋-doped germanate glasses, the maximum of absorption, emission, and gain cross-sections reached a value higher than that reported for fluorozircoaluminate glasses.Hence, these Tm3＋-doped and Ho3＋-doped germanate glasses exhibited an advantage for application in mid-infrared lasers at about 1.8 and 2.0 μm wavelength.

Practical Experience of Establishing German Standard Level 1 Perinatal Center in Chongqing Health Care for Women and Children

Germany,as a western developed country,has an advanced medical level,especially in the health care of very immature premature infants.We trace the medical history of perinatology to understand the development of perinatal centers in Germany.After analyzing the classification and function,hierarchical management and quality control systems of German perinatal centers,we established a German standard level 1 perinatal center in the Chongqing Health Center for Women and Children(CHCWC).During more than two years of practice,we changed concepts,continuously updated clinical knowledge and skills,developed a series o f high-quality work processes and supervision systems and introduced advanced medical equipment.We believe that the experience of establishing a German standard level 1 perinatal center and perinatal center network in Chongqing is worthy of being promoted to the Chinese maternal and child health care system.

国际私法上“调适”的概念(英文)

The true difficulties consist in the adjustment of several internal legal systems working together in respect of the same set of facts.—Martin Wolff①Ⅰ.Introduction:Disharmony in the Regular Choice of Law Process Problems of"adaptation"②or"adjustment"③may arise where the choice of

Results of Sleeve Gastrectomy in Germany—Data on Nationwide Survey on Quality Assurance in Bariatric Surgery in Germany

Background: Since January 1st of 2005, the situation of bariatric surgery is being analyzed in Germany. The data is registered prospectively in cooperation with the Institute of Quality Assurance in Surgery at the Otto-von-Guericke University Magdeburg. Methods: The data is registered through an online database which includes all information for primary and revision bariatric procedures as well as yearly follow-up. Participation in the quality assurance study is optional. All certificated centers have to participate at the survey. Results: From January 2006 to December 2009, 1478 sleeve gastrectomies (SG) were performed at 45 hospitals. The number of procedures has increased from 126 in 2007 to 933 in 2009. The main complication is leakage of the staple-line. Initial leakage rate was 7% in 2007. Leakage rate dropped down to 2.3% in 2008 and 2.5% in 2009. Mean age of patients was 43.1 years and mean BMI was 52.83 kg/m2. Age and BMI were significantly higher in patients with SG than in all other patients undergoing bariatric surgery. Conclusion: SG is a common and hype bariatric procedure in Germany, but postoperative complication rate is high. Data on the long-term effect of SG on weight loss and amelioration of comorbidities need to be evaluated. More detailed analyzes are necessary to establish the position of SG in the bariatric surgery. Further studies should also include examinations on long-term complications and redo-procedure after SG.

Fiduciary Duties in Company Law:A German Perspective

As Chinese practitioners and scholars ponder the scope of fiduciary obligations under the country’s company law,this paper offers a comparative perspective from German law.Although German corporate law has not rejected legal transplants,the common law trust has never been accepted as an organizational device for administering third-party funds or doing business.Nonetheless,the German judiciary has developed a sophisticated concept of fiduciary obligations where the statutes remain silent.This paper explores the application of fiduciary obligations to limited partnerships,limited liability companies,and stock corporations.It takes a membership perspective to ascertain the legal relationships between a corporation and its shareholder-members and among fellow-shareholders,as business entities evolve from personalistic to capitalistic settings.Fiduciary obligations also inform the relationship between the corporation and its directors and corporate officers.Although German law does not classify directors and corporate officers as the shareholders’direct trustees,shareholders stand nonetheless to benefit from the way directors and corporate offices discharge their duties towards the respective corporate entities.Moreover,criminal law rules on embezzlement operate to protect the corporation and the monies it administers from overly risky business projects.