Paradoxical herniation associated with hyperbaric oxygen therapy after decompressive craniectomy: A case report

BACKGROUND Whether hyperbaric oxygen therapy(HBOT)can cause paradoxical herniation is still unclear.CASE SUMMARY A 65-year-old patient who was comatose due to brain trauma underwent decompressive craniotomy and gradually regained consciousness after surgery.HBOT was administered 22 d after surgery due to speech impairment.Paradoxical herniation appeared on the second day after treatment,and the patient’s condition worsened after receiving mannitol treatment at the rehabilitation hospital.After timely skull repair,the paradoxical herniation was resolved,and the patient regained consciousness and had a good recovery as observed at the follow-up visit.CONCLUSION Paradoxical herniation is rare and may be caused by HBOT.However,the underlying mechanism is unknown,and the understanding of this phenomenon is insufficient.The use of mannitol may worsen this condition.Timely skull repair can treat paradoxical herniation and prevent serious complications.

Generalized Einstein-Podolsky-Rosen steering paradox

Quantum paradoxes are essential means to reveal the incompatibility between quantum and classical theories,among which the Einstein–Podolsky–Rosen(EPR)steering paradox offers a sharper criterion for the contradiction between localhidden-state model and quantum mechanics than the usual inequality-based method.In this work,we present a generalized EPR steering paradox,which predicts a contradictory equality“2Q=(1+δ)C”(0≤δ<1)given by the quantum(Q)and classical(C)theories.For any N-qubit state in which the conditional state of the steered party is pure,we test the paradox through a two-setting steering protocol,and find that the state is steerable if some specific measurement requirements are satisfied.Moreover,our construction also enlightens the building of EPR steering inequality,which may contribute to some schemes for typical quantum teleportation and quantum key distributions.

The AI Paradox: Mapping the Unintended Disruptions in IT and Beyond

In the realm of Artificial Intelligence (AI), there exists a complex landscape where promises of efficiency and innovation clash with unforeseen disruptions across Information Technology (IT) and broader societal realms. This paper sets out on a journey to explore the intricate paradoxes inherent in AI, focusing on the unintended consequences that ripple through IT and beyond. Through a thorough examination of literature and analysis of related works, this study aims to shed light on the complexities surrounding the AI paradox. It delves into how this paradox appears in various domains, such as algorithmic biases, job displacement, ethical dilemmas, and privacy concerns. By mapping out these unintended disruptions, this research seeks to offer a nuanced understanding of the challenges brought forth by AI-driven transformations. Ultimately, its goal is to pave the way for the responsible development and deployment of AI, fostering a harmonious integration of technological progress with societal values and priorities.

Solving the Olbers’s Paradox, Explaining the “Red-Shift”, and Challenging the Relativities by “Sun Matters Theory” and “Sun Model of Universe”, an Evolution of the Einstein’s Static Universe Model

Olbers’s paradox, known as the dark night paradox, is an argument in astrophysics that the darkness of the night sky conflicts with the assumption of an infinite and eternal static universe. Big-Bang theory was used to partially explain this paradox, while introducing new problems. Hereby, we propose a better theory, named Sun Matters Theory, to explain this paradox. Moreover, this unique theory supports and extended the Einstein’s static universe model proposed by Albert Einstein in 1917. Further, we proposed our new universe model, “Sun Model of Universe”. Based on the new model and novel theory, we generated innovative field equation by upgrading Einstein’s Field Equation through adding back the cosmological constant, introducing a new variable and modifying the gravitationally-related concepts. According to the Sun Model of Universe, the dark matter and dark energy comprise the so-called “Sun Matters”. The observed phenomenon like the red shift is explained as due to the interaction of ordinary light with Sun Matters leading to its energy and frequency decrease. In Sun Model, our big universe consists of many universes with ordinary matter at the core mixed and surrounded with the Sun Matters. In those universes, the laws of physics may be completely or partially different from that of our ordinary universe with parallel civilizations. The darkness of night can be easily explained as resulting from the interaction of light with the Sun Matters leading to the sharp decrease in the light intensity. Sun Matters also scatter the light from a star, which makes it shining as observed by Hubble. Further, there is a kind of Sun Matters named “Sun Waters”, surrounding every starts. When lights pass by the sun, the Sun Waters deflect the lights to bend the light path. According to the Sun Model, it is the light bent not the space bent that was proposed in the theory of relativities.

Multiple paradoxical embolisms caused by central venous catheter thrombus passing through a patent foramen ovale: A case report

BACKGROUND To date,this is the first case of a paradoxical embolism(PDE)that concurrently manifested in the coronary and lower limb arteries and was secondary to a central venous catheter(CVC)thrombus via a patent foramen ovale(PFO).CASE SUMMARY Here,we report a case of simultaneous coronary and lower limb artery embolism in a PFO patient carrier of a CVC.The patient presented to the hospital with acute chest pain and lower limb fatigue.Doppler ultrasound showed a large thrombus in the right internal jugular vein,precisely at the tip of the CVC.Transthoracic and transesophageal echocardiography confirmed the existence of a PFO,with inducible right-to-left shunting by the Valsalva maneuver.The patient was administered an extended course of anticoagulation therapy,and then the CVC was successfully removed.Percutaneous PFO closure was not undertaken.There was no recurrence during follow-up.CONCLUSION Thus,CVC-associated thrombosis is a potential source for multiple PDE in PFO patients.

Twin Paradox and Proper Time

Professors Mohazzbi and Luo [1] published “Despite several attempts have been made to explain the twin paradox … none of the explanations … resolved the paradox. If the paradox can be ever resolved, it requires a much deeper understanding … of the theory of relativity”. The deeper understanding of resolving the paradox is by applying more explicit definitions of proper time interval, Lorentz transform, time dilation, and aging time.

COVID-19 mortality paradox(United States vs Africa):Mass vaccination vs early treatment

The coronavirus disease 2019(COVID-19)mortality rate in 55 African countries is almost 4.5 times lower than in the coronavirus disease 2019(COVID-19)despite Africa having over 4.2 times more people.This mortality paradox is also evident when comparing Nigeria,a heavily populated,poorly vaccinated and weakly mandated country to Israel,a small,highly vaccinated and strictly mandated country.Nigeria has almost 4 times lower COVID mortality than Israel.In this Field of Vision perspective,I explain how this paradox has evolved drawing upon my academic,clinical and social experience.Since April 2020,I’ve developed and been using the Egyptian immune-modulatory Kelleni’s protocol to manage COVID-19 patients including pediatric,geriatric,pregnant,immune-compromised and other individuals suffering from multiple comorbidities.It’s unfortunate that severe acute respiratory syndrome coronavirus 2 is still evolving accompanied by more deaths.However in Africa,we’ve been able to live without anxiety or mandates throughout the pandemic because we trust science and adopted early treatment using safe,and effective repurposed drugs that have saved the majority of COVID-19 patients.This article represents an African and Egyptian tale of honor.

一类含加权非线性项的Moore-Gibson-Thompson方程初边值问题解的破裂

本文在3维空间外区域(即3维空间中有界区域的补集)中研究了一类包含加权非线性项的Moore-Gibson-Thompson方程初边值问题的解的破裂,其中的边界条件分别为Dirichlet边界条件和Neumann边界条件.本文构造了检验函数,运用迭代方法在次临界和小初值情形下证明问题的解将在有限时间内破裂,并给出了解的生命跨度的上界估计.

后腹腔镜联合Gibson切口多囊肾切除一期同种异体肾移植术3例报道并文献复习

目的探讨多囊肾尿毒症患者采用后腹腔镜联合Gibson切口进行多囊肾切除一期同种异体肾移植的可行性及安全性。方法回顾性分析2015年10月至2016年10月期间收治的3例多囊肾尿毒症患者的临床资料并进行随访。3例患者均采用斜侧卧位后腹腔镜方式切除右侧多囊肾,经Gibson切口取出多囊肾一期行同种异体肾移植手术。统计手术时间、术中出血量、术后胃肠道功能恢复时间及围手术期并发症等指标,术后定期随访,观察移植肾功能及患者存活情况。结果手术均成功完成,1例肾切除手术中转手助腹腔镜,无中转开放手术。手术时间平均3.67 h,术中出血量平均133 ml。术后胃肠道功能恢复时间平均2.7 d。术后伤口疼痛VAS评分平均3.3分,无其它肾切除或肾移植并发症。术后平均随访半年,3例患者均存活,术后1周、1月、3月及半年血肌酐水平分别为143.3μmol/L、128.3μmol/L、90.7μmol/L及80.7μmol/L。结论后腹腔镜联合Gibson切口多囊肾切除一期同种异体肾移植术具有可行性,同时具有创伤小、疼痛轻、恢复快的优势,其安全性尚需进一步验证。

广义Gibson地基中单桩-土-承台共同作用简化分析

基于广义Gibson地基中单桩桩顶支承刚度和地基土支承刚度,结合单桩与承台间等效相互作用系数,建立了单桩–土–承台共同作用方程,提出了广义Gibson地基中单桩–土–承台共同作用简化分析方法。算例分析表明:简化分析结果与有限元分析结果、Butterfield解之间具有良好的一致性,验证了简化分析方法的合理性。参数分析表明:当桩的长径比l/d≥30,且承台与桩的半径比n≤4时,承台分担荷载较小,承台对带台单桩基础整体支承刚度的影响可忽略不计;弹性模量增加系数kE对带台单桩基础性状的影响比较明显,基础整体支承刚度与kE近似成线性增加关系。

Gibson大变形固结理论的一种连续介质力学表述

为了克服Gibson大变形固结理论的一维局限性,提出了一个新的连续介质力学模型,其中,采用第2类Piola-Kirchhoff应力和Green应变分别替代Lagrange应力和孔隙比。该模型可以考虑土体压缩性和渗透性的非线性变化以及几何非线性,并具有易于推广到多维模型的优势。结合试验资料,探讨了新模型的固结系数和对流系数的变化规律,结果表明,对流系数随着应变增加而减小,反映了大变形固结过程中土体自重效应在不断减弱。

Gibson地基半透水边界一维固结分析

针对单层Gibson地基模型,研究了半透水边界饱和土层在各种荷载作用下有效应力以及固结度的变化.运用Laplace变换求得了频域内有效应力在任意荷载作用下的解,并结合数值Laplace逆变换,对几种常见荷载作用下的固结进行了讨论,通过具体算例研究了各土性参数对固结的影响.结果表明,半透水边界Gibson地基的一维固结与传统固结理论有一定的差异.

埋置点源简谐荷载作用下Gibson土体动力Green函数

采用Hankel积分变换方法,研究了Gibson地基在内源简谐荷载作用下的动力响应问题;通过构造积分围道技术,利用对围道上奇点的特殊处理,以消除驻波相来满足实际波的辐射条件,得到了Gibson地基埋置点源简谐荷载的动力Green函数。通过具体算例,分析了地基土体非均质性、荷载埋置深度和激振频率等因素对地基土体表面竖向位移的影响。结果显示:(1)荷载埋置深度和荷载激振频率对地基表面位移幅值大小和波动性都影响较大;(2)低频荷载作用下,地基土体的非均质性对其表面位移有较大影响。

双层广义Gibson地基轴对称问题求解

假定双层地基土体为弹性、不可压缩、剪切模量随深度线性变化的广义Gibson地基,在两层土体剪切模量表达式常数项与一次项系数之比相同条件下,采用Hankel变换,得到了表面分布轴对称荷载时地基土体应力、位移的积分形式解,讨论了下层深度、剪切模量等对位移的影响。获得的解可退化到半空间情况。

移动荷载下下卧基岩Gibson地基的动力响应

针对G ibson地基模型,研究了在移动荷载作用下土体的动力响应。基于弹性方程,通过傅立叶级数展开将偏微分方程转化成常微分方程求解,得出了下卧基岩G ibson地基在移动荷载作用下土体中各点的响应,并讨论了在参数变化时土体各点响应的变化。从分析结果来看,表面土体的剪切模量G0的增大、剪切模量变化率α的增大、荷载移动速度c的减小和层厚H的减小都使土体中各点的竖直方向位移减小,当层厚到一定厚度时,可以忽略下卧基岩的影响,简化为半空间模型来考虑。

Gibson地基的一维固结解

针对单层Gibson地基模型,运用Laplace变换,求得了单层Gibson地基的一维固结问题,得到了频域内的通解。通过Laplace逆变换,即可计算单层Gibson地基在任意荷载下的一维固结特性。此外,结合工程实例,对解进行了探讨,揭示了单层Gibson地基的固结特性。

成层Gibson地基中单桩沉降的非线性分析

针对成层Gibson地基模型,研究了轴向荷载作用下单桩的非线性沉降响应。利用最小势能原理求得桩土体系的控制方程,获得了土体位移的解析解及桩身沉降的差分方程式。将土体看作线弹性理想塑性材料,分析了土体的非线性对桩身位移的影响,提出了考虑非线性的单桩沉降响应计算方法,利用Maple编制了相应的分析程序。通过算例研究了土性参数及桩长径比对端承单桩沉降的影响。将研究结果应用于桩基静载荷试验成果的分析,结果表明,两者吻合较好,证明了该方法的合理性。

基于广义Gibson模型的大面积荷载下地基沉降计算方法

随着经济的快速发展,我国大型建(构)筑物、围海造地和场地形成工程日益增多,大面积荷载下的地基沉降问题日益突出,因此开展大面积荷载作用下地基的沉降计算理论研究具有重要的理论价值和现实意义。基于广义Gibson地基模型,考虑地基参数随深度变化的非均质性,求解出大面积荷载作用下地基中心点的竖向位移解析解,利用解析分析对"大面积"荷载进行了讨论与定义。最后,通过上海某大面积场地形成工程实例和三维数值模拟验证了该方法的可行性。结果表明,该计算方法能够较好地反映大面积荷载作用下地基的沉降规律,对于实际工程中预测大面积荷载下地基沉降具有应用价值。

广义Gibson地基上无限大薄板轴对称问题求解

Gibson地基是指一种土体不可压缩,剪切模量随深度线性变化的非均质线弹性地基,如果地基表面处剪切模量不为零,被称为广义Gibson地基.利用Hankel变换,推导了广义Gibson地基上无限大薄板在一般轴对称荷载作用下,板和地基土体的应力位移的积分形式解,采用数值方法,讨论了地基的非均质性对板内弯矩的影响,结果显示:1.在最大弯矩区域内,相对于均质弹性地基上的板,Mr和Mθ的值都减小;2.地基非均质性影响板内弯矩的分布,对Mr的影响更大,局部区域内,弯矩的方向可能与均质弹性情况下相反,绝对值更大.获得的解可以退化到均质弹性情况下的解.

成层Gibson地基半透水边界一维固结解

针对成层Gibson地基模型,研究了半透水边界饱和土层在各种荷载作用下有效应力以及沉降的变化.运用Laplace变换求得了频域内有效应力在任意荷载作用下的解,并结合数值Laplace逆变换,对几种常见的荷载作用下的固结进行了讨论,通过具体算例研究了各土性参数对固结的影响.在实际工程计算中,应根据土层和垫层的具体情况,确定边界条件属于完全透水、半透水或不透水,从而得到更为准确的结果.循环荷载作用下成层Gibson地基固结,其有效应力和变形都呈振荡增长,由于水的存在,两者的变化步调不与荷载同步,这一点与弹性单相介质在循环荷载作用下的规律不同.对于双面排水地基,靠近土层上下表面处应力振荡幅值较大,滞后时间较小;本文计算模型中假设压缩模量只随深度变化,不随时间变化,因此有效应力及变形振荡较大,而实际工程中,由于压缩模量随加载过程的顺延有增长趋势,故可以想像随时间增长,时间有效应力和变形的振荡幅度将减小.