Distribution Law of Goblet Cells in the Intestinal Tracts of African Ostrich Chicks

[Objective] This study aimed to investigate the distribution law of different goblet cells in the intestinal tracts of African ostrich chicks. [Method] Alcian blue/pe- riodic acid-schiff reaction （AB/PAS） was adopted to observe and analyze the types and distribution of goblet cells in the intestinal tracts of ostrich chicks. Acid mu- copolysaccharide could be stained blue with alcian blue （AB）, and neutral mu- copolysaccharide could be stained red with periodic acid-schiff reagent （PAS）. [Result] According to AB/PAS results, goblet cells in the intestinal tracts were divided in- to four types： TypeⅠ was pure red, with AB negative result and PAS positive result containing neutral mucoitin; type Ⅱ was pure blue, with AB positive result and PAS negative result containing acidic mucoitin; type Ⅲ was purple reddish, with PAS posi- tive result greater than AB; typeⅣ was purple blue, with AB positive result greater than PAS. Large quantities of goblet cells were found in the intestinal tracts of os- trich chicks, mostly type III and IV.The quantities of goblet cells were decreased gradually in the duodenum, jejunum and ileum, while the quantities were increased in the cecum, colon and rectum. The goblet cells in the large intestine are more than that in the small intestine. The most quantities of goblet cells were contained in rectum. [Conclusion] These results indicate that the distribution of goblet cells is closely related with the structure and function of intestinal tracts. The mucus secret- ed by the goblet Cells plays a series of important roles in the digestion and mucosal immunization.

十二指肠炎症、溃疡发生机理探讨

对７４例十二指肠溃疡、６０例胃小弯溃疡、９８例胃窦癌之大部切除胃标本的十二指肠球部组织，检验了它们的胃上皮化生，ＰＡＳ阳性杯状细胞（不完全小肠型肠腺）和幽门弯曲菌（ＣＰ）。结果说明，十二指肠的胃上皮化生与胃部病变性质关系不大；由幽门与十二指肠球部之间可能存在移行区，两者的炎症和溃疡之发生机理也应相似；至于ＣＰ，其存在则对十二指肠炎症（溃疡）的出现起着一定的促进作用。