Background: A subset of cancer is particularly vulnerable to hydration prior to chemotherapy protocols;however, real-world outcomes-based data on pre-hydration elements of patients with tumor is sparse. Case Presentat...Background: A subset of cancer is particularly vulnerable to hydration prior to chemotherapy protocols;however, real-world outcomes-based data on pre-hydration elements of patients with tumor is sparse. Case Presentations: This retrospective case series describes a cohort of adult patients with terminal stage cancer who were seen between July 1, 2023, and September 25, 2023 and underwent various chemotherapy protocols, which, to our knowledge, represents comprehensive analysis of this patient population. We performed a retrospective search of patients identifying 50 cases of the chemotherapies of patients with cancer and extracted the clinical data via individual chart reviews. At the time of diagnosis, 24 patients were prehydrated with NaCl with KCl prior to the chemotherapy against the tumor, and 26 patients were taking normal saline only before undergoing cancer-specific treatment. Hydration and, prior chemotherapeutic agents use were the most common predepositse. Carcinomatosis peritoneii were the most common signs of the terminal stage of cancer within patients. Twenty-four patients were admitted to the hospital and two received NaCl with KCl hydaration prior to the platinum based chemotherapeutic agent treatment. Twenty-six patients received only normal saline hydration. Conclusion: Our data suggest that NaCl with KCl prehydaration results in better prognosis, including reduced tumor burden or decreased lymph node invasion, when compared to other vulnerable patients populations that receive only normal saline hydration. The graphene exfoliation effect of NaCl with KCl may have contributed to these results.展开更多
文摘Background: A subset of cancer is particularly vulnerable to hydration prior to chemotherapy protocols;however, real-world outcomes-based data on pre-hydration elements of patients with tumor is sparse. Case Presentations: This retrospective case series describes a cohort of adult patients with terminal stage cancer who were seen between July 1, 2023, and September 25, 2023 and underwent various chemotherapy protocols, which, to our knowledge, represents comprehensive analysis of this patient population. We performed a retrospective search of patients identifying 50 cases of the chemotherapies of patients with cancer and extracted the clinical data via individual chart reviews. At the time of diagnosis, 24 patients were prehydrated with NaCl with KCl prior to the chemotherapy against the tumor, and 26 patients were taking normal saline only before undergoing cancer-specific treatment. Hydration and, prior chemotherapeutic agents use were the most common predepositse. Carcinomatosis peritoneii were the most common signs of the terminal stage of cancer within patients. Twenty-four patients were admitted to the hospital and two received NaCl with KCl hydaration prior to the platinum based chemotherapeutic agent treatment. Twenty-six patients received only normal saline hydration. Conclusion: Our data suggest that NaCl with KCl prehydaration results in better prognosis, including reduced tumor burden or decreased lymph node invasion, when compared to other vulnerable patients populations that receive only normal saline hydration. The graphene exfoliation effect of NaCl with KCl may have contributed to these results.
