期刊文献+
共找到70篇文章
< 1 2 4 >
每页显示 20 50 100
Adult-Type Granulosa Cell Tumor with Similar Clinical Findings Seen during Ovarian Cystectomy Performed at the Same Time as Laparoscopic Ovarian Drilling for Polycystic Ovarian Syndrome: An Extremely Rare Case
1
作者 Remi Nakajima Risa Kobayashi +4 位作者 Marie Kawai Eriko Sakamoto Miho Matsuda Rieko Kanda Makoto Kawamura 《Open Journal of Obstetrics and Gynecology》 2024年第8期1197-1206,共10页
Polycystic ovary syndrome (PCOS) is a major cause of anovulatory infertility. Laparoscopic ovarian drilling (LOD) is a treatment for PCOS that allows the laparoscopic identification of other intra-abdominal lesions an... Polycystic ovary syndrome (PCOS) is a major cause of anovulatory infertility. Laparoscopic ovarian drilling (LOD) is a treatment for PCOS that allows the laparoscopic identification of other intra-abdominal lesions and the provision of diagnostic treatment. This study reports a case of PCOS with an ovarian mass in which LOD was aggressively used and a granulosa cell tumor (GCT) was found. A 34-year-old woman with secondary amenorrhea and irregular menstrual cycles presented to the emergency department with abdominal pain of unknown etiology. Imaging studies revealed a 6-cm left ovarian mass with an internal appearance suggestive of a hemorrhage. The patient’s secondary amenorrhea was subsequently diagnosed as PCOS, and LOD was performed to preserve her fertility. Simultaneously, a cystectomy was performed to evaluate the tumor in the left ovary;the diagnosis was adult-type GCT. Although concomitant GCT and PCOS are extremely rare, the two conditions have similar clinical manifestations. In women of reproductive age, the impact of surgery on future fertility should be considered, and the initial surgical technique should be chosen carefully. 展开更多
关键词 Polycystic Ovary Syndrome Laparoscopic ovarian Drilling granulosa cell tumor
下载PDF
Ovarian juvenile granulosa cell tumor associated with Maffucci’s syndrome: case report 被引量:3
2
作者 袁键群 林小娜 +2 位作者 许敬尧 祝佳 郑伟良 《Chinese Medical Journal》 SCIE CAS CSCD 2004年第10期1592-1594,共3页
关键词 ovarian neoplasms granulosa cell tumors Maffucci’s syndrome ENCHONDROMATOSIS
原文传递
Clinicopathological Evaluation of Ovarian Juvenile Granulosa Cell Tumor: Is Fertility-Sparing Surgery Safe?
3
作者 Lu Guo Xiao-Cheng Liu +3 位作者 Xiu-Ying Chen Xi-Rong Xiao Yu-Qing Qu Bin Li 《Reproductive and Developmental Medicine》 CSCD 2019年第1期24-29,共6页
Objective:To retrospectively investigate the clinicopathological characteristics of ovarian juvenile granulosa cell tumors(JGCTs)and to evaluate the safety of fertility-sparing surgery.Methods:In this study,surgically... Objective:To retrospectively investigate the clinicopathological characteristics of ovarian juvenile granulosa cell tumors(JGCTs)and to evaluate the safety of fertility-sparing surgery.Methods:In this study,surgically treated patients with JGCTs diagnosed between January 2004 and October 2018 in our center were identified.Clinicopathological data,survival outcomes,and recurrence rates were examined in these patients.Results:A total of 8 patients were included.All patients were premenarchal girls or young women(age range,9-32 years).Irregular vaginal bleeding was the most common presenting symptom.Of them,seven patients were classified with Stage I JGCTs,and they underwent fertility-sparing surgery.One patient who had Stage IIIC JGCT and had completed childbearing underwent complete surgery.Seven patients received adjuvant chemotherapy.The median follow-up duration in the total cohort was 64 months(range,2-117 months).The overall survival rate in the fertility-sparing group was 100%,whereas the patient with Stage IIIC JGCT died 1 month after the treatment.Conclusions:Fertility-sparing surgery might not show a negative impact on oncologic outcomes.Fertility sparing could be considered a modified option for patients with Stage I JGCTs.However,due to the limited number of patients,the conclusion must be interpreted with caution,and larger or multicenter studies are needed before conclusions can be drawn. 展开更多
关键词 Adjuvant Chemotherapy Complete Surgery Fertility-Sparing Surgery ovarian Juvenile granulosa cell tumor
原文传递
Apoptosis and Expression of Protein TRAIL in Granulosa Cells of Rats with Polycystic Ovarian Syndrome 被引量:5
4
作者 张娟 朱桂金 +2 位作者 王昕荣 徐蓓 胡琳莉 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2007年第3期311-314,共4页
The relationship between apoptosis of granulosa cells and follicle development arrest in polycystic ovarian syndrome (PCOS) rats, and the contribution of tumor necrosis factor related apoptosis inducing ligand (TRAIL)... The relationship between apoptosis of granulosa cells and follicle development arrest in polycystic ovarian syndrome (PCOS) rats, and the contribution of tumor necrosis factor related apoptosis inducing ligand (TRAIL) in apoptosis of granulosa cells were explored. By using sodium prasterone sulfate rat PCOS model was induced. The apoptosis of granulosa cells in ovaries of rats was observed by TdT-mediated dUTP-biotin nick end-labeling (TUNEL), and the expression of TRAIL protein and mRNA in granulosa cells was detected by using immunhistochemical staining and reverse transcription polymerase chain reaction (RT-PCR) respectively. The apoptotic rate and the expression of protein TRAIL in granulosa cells were significantly higher in antral follicles from the PCOS rats than in those from the control rats (P<0.01, P<0.05). There was no significant difference in apoptotic rate and the expression of TRAIL protein in granulosa cells of preantral follicles between the PCOS rats and the control rats (P>0.05). No apoptosis and the expression of TRAIL protein in granulosa cells of primordial follicles were found in the two groups. The expression of TRAIL mRNA was significantly stronger in granulosa cells from the PCOS rats than in those from the con- trol rats (P<0.01). It was suggested that the apoptotic rate in granulosa cells was significantly higher in antral follicle from the PCOS rats than in those from the control rats. TRAIL played a role in regu- lating the apoptosis of granulosa cells in PCOS rats. 展开更多
关键词 tumor necrosis factor related apoptosis inducing ligand granulosa cell APOPTOSIS polycystic ovarian syndrome RAT
下载PDF
成人型卵巢颗粒细胞瘤的MRI诊断价值及临床分析
5
作者 张翼 张静 《中国CT和MRI杂志》 2024年第6期136-137,共2页
目的 探讨成人型卵巢颗粒细胞瘤的MRI表现及其临床特点,提高成人型卵巢颗粒细胞瘤的诊断能力。方法 回顾性分析19例经手术及病理证实的成人型卵巢颗粒细胞瘤的M RI表现及临床资料。结果 19例患者平均年龄为44.4±11.5岁,其中未绝经... 目的 探讨成人型卵巢颗粒细胞瘤的MRI表现及其临床特点,提高成人型卵巢颗粒细胞瘤的诊断能力。方法 回顾性分析19例经手术及病理证实的成人型卵巢颗粒细胞瘤的M RI表现及临床资料。结果 19例患者平均年龄为44.4±11.5岁,其中未绝经患者12人,平均年龄为37.6±7.7岁,绝经患者7人,平均年龄为57.3±2.4岁。18位患者有临床症状,以月经不规律及绝经后阴道出血为主。其中11位患者有激素检查结果,72.7%雌激素水平升高,卵泡刺激素水平均下降。MRI上18例为单侧肿块,1例为双侧,多表现为实性肿块内多发囊性灶及出血。T_(1)WI上以低信号为主,80%可见出血灶;T_(2)WI以高信号为主,85%可见“蜂窝征”及“海绵征”。结论 结合成人型卵巢颗粒细胞瘤特征MRI表现和临床特点,对于提高该病的术前诊断具有重要意义。 展开更多
关键词 卵巢 颗粒细胞瘤 mri 临床分析
下载PDF
THE MODIFIED RADIOIMMUNOASSAY OF SERUM INHIBIN AND ITS VALUE IN MONITORING OVARIAN TUMOR
6
作者 隋龙 张令浩 +5 位作者 王成海 由振东 刘东 罗建华 金志军 朱明伟 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1999年第2期142-146,共5页
Objectives and Methods: A modified radioimmunoassay (RIA) of serum inhibin (INH) was developed and applied to measure serum INH contents in 39 fertile and 16 postmenopausal women. Thirty-three cases of ovarian tumors,... Objectives and Methods: A modified radioimmunoassay (RIA) of serum inhibin (INH) was developed and applied to measure serum INH contents in 39 fertile and 16 postmenopausal women. Thirty-three cases of ovarian tumors, including granulosa cell tumors and other kinds of ovarian tumors, were monitored by serum INH RIA. Results: The mean value of serum INH contents in follicular, peri-ovulatory and mid-luteal phases of fertile women were 9.48±7.10 pg/ml (2.04~18.53pg/ml), 19.04±9.73 pg/ml (3.49~33.26 pg/ml) and 131.13±110.81 pg/ml (3.49~ 341.10 pg/ml), respectively. Serum INH concentration was negatively correlated with serum FSH concentration, (rs=?0.483,P<0.01). Serum IHN contents were less than 3.6 pg/ml in normal postmenopausal women. The mean value of serum INH contents in ovarian granulosa cell tumor, thecoma, mucinous cystadenocarcinoma and malignant teratoma cases were significantly higher than that of other ovarian tumors, (P<0.01). Serum INH contents were elevated in ovarian granulosa cell tumor, thecoma, mucinous cystadenocaricinoma and endometrioid carcinoma cases with serum CA-125 values in normal range before operation, but serum INH contents decreased to normal range within one week after operation. And consecutive serum INH RIA could be a valuable tool in monitoring for therapeutic effect. Conclusion: Modified INH RIA was of convenient, time-saving and quantitative characteristics, especially with its high sensitivity (<1 pg/ml). There was a regular change of serum INH concentrations during menstrual cycle. INH could inhibit the synthesis and secretion of follicle stimulating hormone (FSH). INH would become a valuable marker for ovarian tumor. INH RIA combined with the measurement of serum CA-125 would be helpful to the early diagnosis, treatment and follow-up for ovarian cancer. 展开更多
关键词 INHIBIN ovarian tumor granulosa cell tumor RADIOIMMUNOASSAY CA-125
下载PDF
Ovarian Sex Cord-Stromal Tumors in Postmenopausal Women and Total Laparoscopical Management
7
作者 Andrea Tinelli Marcello Pellegrino +1 位作者 Vincenzo Emanuele Chiuri Antonio Malvasi 《Journal of Cancer Therapy》 2010年第1期31-35,共5页
BACKGROUND: Ovarian sex-cord stromal tumors (SCST) take up 5% of the ovarian neoplasm and may develop in?to?an ovarian mass or a haemoperitoneum. The surgical management of SCST in early-stage adult patients is not we... BACKGROUND: Ovarian sex-cord stromal tumors (SCST) take up 5% of the ovarian neoplasm and may develop in?to?an ovarian mass or a haemoperitoneum. The surgical management of SCST in early-stage adult patients is not well?defined. CASE REPORT: A 69 year-old postmenopausal woman was admitted for metrorrhagia, a right ovary mass and?increasing pelvic pain. Preoperative clinical and instrumental examination suspected an ovarian tumor, and the?laparoscopic right ophorectomy and the frozen section suggested an ovarian SCST. To fast restore and preserve woman?integrity, total laparoscopic hysterectomy (TLH) plus left salpingo-ophorectomy (SO) were performed, without complications?in the short and long term follow-up. CONCLUSION: In the authors’ opinion, the minimally invasive management?of SCST by TLH plus bilateral SO followed by a prolonged surveillance and without intensive surgical staging,?could be an appropriate clinical and surgical choice in elder patient at early stage, since these tumors are slow at?growth, recurring locally and only a long time after initial treatment. We suggest, after a minimally invasive treatment,?a possible “wait and see” option, as in our case report. 展开更多
关键词 MENOPAUSE LAPAROSCOPY ovarian Cancer Sex Cord-Stromal ovarian tumorS granulosa cell tumorS MINIMALLY Invasive Treatment.
下载PDF
A Retrospective Study of Ovarian Sex Cord Stromal Tumors at the Egyptian National Cancer Institute
8
作者 Ihab Samy Fayek Gamal Amira +1 位作者 Nevine Fayez Habashy Mohamed A. Abd Elrauf Attia 《Journal of Cancer Therapy》 2019年第12期920-937,共18页
Background: Ovarian sex cord-stromal tumors are an uncommon heterogeneous group of tumors with different biological behaviors and clinico-patho- logic aspects. Aim of the Work: This study will review the clinico-patho... Background: Ovarian sex cord-stromal tumors are an uncommon heterogeneous group of tumors with different biological behaviors and clinico-patho- logic aspects. Aim of the Work: This study will review the clinico-pathologic aspects of sex-cord stromal ovarian tumors at the National Cancer Institute (NCI), Cairo University, Egypt, as well as their management and follow-up regarding disease free survival and overall survival. Patients and Methods: This retrospective study was conducted at the National Cancer Institute Cairo University, Egypt on female patients with ovarian sex cord stromal tumors in the period from January 2008 to December 2012 with a follow-up period of 24 to 84 months. The age of the patients, different clinical presentations, radiological findings, associated uterine bleeding (need for endometrial biopsy), pre-operative CA125 levels, surgical management done, different histopathological types, different biological behaviors, presence of ascites (and its correlation with the histopathology), Adjuvant chemotherapy (according to biological behavior and pathological type), and follow-up of non-benign cases for up to 84 months will all be documented and studied. Results: The mean age at presentation was 47.34;abdominal pain and mass were the commonest presentations 54.5% and 53.2% respectively;the main radiologic findings were a pelvic mass +/- ascites which had no correlation to the pathological type (p = 0.075). Endometrial hyperplasia and endometrial carcinoma were associated with 22% and 2.5% of cases respectively. Stages I and II represented 95% of patients with non-benign tumors (48 patients). Panhysterectomy +/- infracolic omentectomy or fertility sparing surgery were done in 70.1% and 29.9% of patients respectively. AGCTs were the commonest pathological type (49.4%). Adjuvant chemotherapy was given to 14 patients (46.7%) with non-benign tumors. 6 recurrences (20%) in 30 patients with non-benign tumors on regular follow-up were documented. The median of disease free survival (DFS) was 50.5 months. The median overall survival was 49.5 months. Conclusion: Ovarian SCSTs are uncommon neoplasms with different biological behaviors where AGCTs are the commonest among Egyptian females. Hormonal manifestations are uncommon where abnormal vaginal bleeding is the commonest one. The presence of ascitic fluid has no correlation with the pathological type of the tumor. Early stages (I and II) represented about 95% of non-benign tumors. Surgical management without lymphadenectomy +/- adjuvant chemotherapy is the main line of treatment at our institute. The OS was shorter than that documented in the literature. A small number of patients, reluctance of follow-up and unavailability of some patients’ data were the main drawbacks in this study. 展开更多
关键词 ovarian SEX CORD STROMAL tumors National Cancer Institute Egypt granulosa cell tumor
下载PDF
卵巢颗粒细胞瘤的MRI诊断 被引量:27
9
作者 刘波 魏光师 +1 位作者 陈树良 周霞 《临床放射学杂志》 CSCD 北大核心 2003年第4期295-297,共3页
目的 分析卵巢颗粒细胞瘤的MRI特征。资料与方法 回顾性分析 15例卵巢颗粒细胞瘤的MRI特征 ,并与手术及病理对照研究。结果  15例中 ,囊实性肿块 8例 ,内有多发大小不等的囊性变 ,囊内壁光滑 ,囊内容物MRT1WI呈等低混杂信号 ,T2 WI... 目的 分析卵巢颗粒细胞瘤的MRI特征。资料与方法 回顾性分析 15例卵巢颗粒细胞瘤的MRI特征 ,并与手术及病理对照研究。结果  15例中 ,囊实性肿块 8例 ,内有多发大小不等的囊性变 ,囊内壁光滑 ,囊内容物MRT1WI呈等低混杂信号 ,T2 WI呈混杂高信号 ,囊与囊间有厚壁分隔 ;实性肿块 3例 ,T1WI及T2 WI信号均高于肌肉 ;单一较大的囊性病灶 4例。 13例子宫均匀增大 ,内膜增厚 ,1例并有子宫内膜癌。结论 诊断卵巢颗粒细胞瘤的可靠依据为 :(1)肿瘤内多发囊变 ,间有厚壁分隔 ,囊内壁光滑 ;(2 )合并子宫体积增大 ,内膜增生。 展开更多
关键词 卵巢颗粒细胞瘤 mri 诊断 磁共振成像 手术切除
下载PDF
卵巢颗粒细胞瘤的MRI和CT特征性表现及与病理对照 被引量:38
10
作者 邹玉坚 郑晓林 +2 位作者 李建鹏 王刚 杨沛钦 《中国CT和MRI杂志》 2015年第7期87-91,共5页
目的探讨卵巢颗粒细胞瘤的MRI及CT特点,提高诊断与鉴别诊断能力。方法回顾性分析12例经手术病理证实的卵巢颗粒细胞瘤MRI及CT表现,并与病理对照,总结其MRI及CT特征。结果 12例肿瘤均为单侧,类圆形,包膜完整的囊实性肿块。其中11例行MR平... 目的探讨卵巢颗粒细胞瘤的MRI及CT特点,提高诊断与鉴别诊断能力。方法回顾性分析12例经手术病理证实的卵巢颗粒细胞瘤MRI及CT表现,并与病理对照,总结其MRI及CT特征。结果 12例肿瘤均为单侧,类圆形,包膜完整的囊实性肿块。其中11例行MR平扫,实性部分呈等/稍长T1稍长T2信号;1例行CT检查、呈等密度影。肿瘤内含较多囊腔,小囊呈"蜂窝状"或"海绵状",较大的囊腔囊壁和间隔厚而均匀。9例肿瘤部分囊腔内含血性信号/密度。增强扫描肿瘤实性部分明显强化,MRI平均信号强度略低于子宫肌层(病变信号值约为476.10±73.33,子宫肌层信号值为505.73±64.99)。所有患者子宫内膜均有不同程度增厚。大体病理标本切面与MRI/CT表现相符合,12例肿瘤部分囊腔内均见暗红色血液或血凝块。病理诊断:10例为成年型卵巢颗粒细胞瘤,其中低分化3例,2例腹膜、肠壁、输卵管见转移灶;中分化2例。2例为幼年型颗粒细胞瘤。子宫内膜均为增生期改变,部分患者见息肉、子宫内膜癌。结论卵巢颗粒细胞瘤的MRI/CT具有一定特征,结合性激素所致的临床症状,能明确诊断。 展开更多
关键词 卵巢 颗粒细胞瘤 mri CT 病理对照 诊断及分析
下载PDF
成人型卵巢颗粒细胞瘤的MRI特征表现与病理相关性分析 被引量:13
11
作者 李铭 段成洲 +2 位作者 张耀文 夏旭东 张玉兴 《中国CT和MRI杂志》 2018年第6期89-92,共4页
目的探讨卵巢颗粒细胞瘤的MRI特征表现,与术后病理结果对照。方法回顾性分析40例外科切除后经病理证实的成人型卵巢颗粒细胞瘤患者的临床及MRI影像资料,评析MRI影像的特征表现及对应之病理基础。结果 40例患者病灶均为单发,MRI平扫的主... 目的探讨卵巢颗粒细胞瘤的MRI特征表现,与术后病理结果对照。方法回顾性分析40例外科切除后经病理证实的成人型卵巢颗粒细胞瘤患者的临床及MRI影像资料,评析MRI影像的特征表现及对应之病理基础。结果 40例患者病灶均为单发,MRI平扫的主要影像表现:子宫附件区边界清楚、包膜完整的囊实性、囊性或实性肿块。23例为多房蜂窝状囊实性肿块,T1WI呈等低混杂信号,T2WI呈混杂高信号,内有大小不等的囊变灶,囊内壁光滑,无明确壁结节;11例为囊性肿块,单房或多房性,直径多大于8cm,其囊内壁均较光滑,囊内T1WI呈均匀一致低信号,T2WI呈一致高信号;6例为实性肿块,大小约3-5cm,T1WI大致等同于同层肌肉信号、T2WI高于同层肌肉信号。增强扫描40例患者肿瘤实性部分及囊内分隔均明显强化,囊内部分无强化表现;27例有腹水的患者,其腹水含量与肿瘤大小无相关性(r=0.19,P=0.08)。结论成人型卵巢颗粒细胞瘤在MRI影像表现上具有一定的特征性,其特征影像表现为:(1)附件区呈蜂窝状囊实性肿块,房间隔纤细,囊内壁光滑,无壁结节最具有特征性;(2)囊性或实性肿块边界清晰,肿瘤信号均匀一致,多有假包膜。成人型卵巢颗粒细胞瘤的MRI影像表现与病理表现基本吻合。 展开更多
关键词 卵巢 颗粒细胞瘤 磁共振成像
下载PDF
卵巢颗粒细胞瘤的MRI表现及与病理对照分析 被引量:6
12
作者 林开武 周作福 +2 位作者 薛晓铃 刘朝禄 陈春霞 《医学影像学杂志》 2020年第9期1665-1668,共4页
目的探讨卵巢颗粒细胞瘤MRI特点,以提高其诊断与鉴别诊断能力。方法回顾性分析25例经手术病理证实的卵巢颗粒细胞瘤MRI资料,并与病理结果对照,总结MRI的表现特征及其与病理改变的相关性。结果25例患者中幼年型4例,其中囊性1例,实性1例,... 目的探讨卵巢颗粒细胞瘤MRI特点,以提高其诊断与鉴别诊断能力。方法回顾性分析25例经手术病理证实的卵巢颗粒细胞瘤MRI资料,并与病理结果对照,总结MRI的表现特征及其与病理改变的相关性。结果25例患者中幼年型4例,其中囊性1例,实性1例,囊实性2例;成人型21例,囊性3例,实性4例,囊实性14例,所有肿瘤均包膜完整,呈类卵圆形,8例边缘呈分叶状,所有病灶囊性部分呈稍长T 1、长T 2信号影,实质性部分呈稍长T 1、稍长T 2信号影,分隔及囊壁呈稍低信号影,其中6例行动态增强扫描,实质性部分呈速升-平台曲线,峰值低于邻近子宫肌层,另外13例行多期增强扫描,病灶实质性部分及分隔均呈明显强化,实质部分强化程度低于同层子宫肌层,肿瘤内部小囊腔及囊性部分壁呈“渔网状”或“蜂窝状”强化,13例肿瘤部分囊腔内合并出血信号影,大体病理标本切面与MRI表现相符合,另16例患者内膜增厚,其中5例子宫内膜不典型增生,1例子宫内膜癌,6例合并子宫肌瘤,1例伴有卵巢液性乳头状瘤,3例合并子宫内膜异位囊肿。结论卵巢颗粒细胞瘤的MRI具有一定特征,结合临床相关症状及激素改变,对于该病的术前诊断及鉴别诊断能够提供重要的诊断依据。 展开更多
关键词 卵巢 颗粒细胞瘤 病理对照 磁共振成像
下载PDF
复发性卵巢颗粒细胞瘤的治疗选择及预后
13
作者 陈艳东 李俊玉 +2 位作者 赵焕焕 石宁宁 李利 《实用癌症杂志》 2024年第4期686-690,共5页
目的探讨复发性卵巢颗粒细胞瘤(ovarian granulosa cell tumor,OGCT)的临床特征,分析其预后影响因素,评估治疗方案。方法回顾性研究38例复发性OGCT患者的临床特征、复发后治疗方法及生存情况。结果38例复发性OGCT患者的中位复发时间为6... 目的探讨复发性卵巢颗粒细胞瘤(ovarian granulosa cell tumor,OGCT)的临床特征,分析其预后影响因素,评估治疗方案。方法回顾性研究38例复发性OGCT患者的临床特征、复发后治疗方法及生存情况。结果38例复发性OGCT患者的中位复发时间为62.5个月(12~308个月),复发后中位生存时间为33个月(9~106个月)。复发性OGCT患者的1年生存率92%,3年生存率71.9%,5年生存率55.5%。单因素分析显示,复发病灶数目、复发后手术治疗是复发性OGCT患者生存预后的影响因素(P>0.05),多因素生存分析结果显示,复发后手术治疗是复发性OGCT患者生存预后的影响因素(P<0.05)。对27例接受手术治疗的复发性患者单因素分析显示,手术残留病灶是复发性OGCT患者术后再次复发的独立危险因素(P<0.05)。结论复发性OGCT的化疗敏感性较低,手术是复发性OGCT最主要的治疗方法,尽可能完整切除可以降低再次复发风险,提高生存率。 展开更多
关键词 复发性卵巢颗粒细胞瘤 临床特征 治疗方法 预后
下载PDF
MRI在卵巢纤维-卵泡膜细胞瘤诊断中应用的价值 被引量:1
14
作者 肖慧君 康正武 +2 位作者 王俊杰 詹阿来 黄庆文 《中国卫生标准管理》 2017年第19期128-132,共5页
目的探讨MRI在卵巢纤维-卵泡膜细胞瘤诊断中应用的价值。方法选取我院2014年1月—2016年12月经手术和病理证实为卵巢纤维-卵泡膜细胞病例32例,分析患者的MRI表现,并与病理结果进行比较。结果 MRI表现:32例卵巢纤维-卵泡膜细胞瘤病例均... 目的探讨MRI在卵巢纤维-卵泡膜细胞瘤诊断中应用的价值。方法选取我院2014年1月—2016年12月经手术和病理证实为卵巢纤维-卵泡膜细胞病例32例,分析患者的MRI表现,并与病理结果进行比较。结果 MRI表现:32例卵巢纤维-卵泡膜细胞瘤病例均单侧肿瘤,边界清楚,表现圆、椭圆形、部分哑铃形或分叶状。4例表现为囊实性,28例为实性。T1WI上31例实性肿块或实性成分显示低或等信号,仅1例表现稍高信号;T2WI上实性肿块或实性成分信号多样:6例为均匀或不均匀稍低信号,增强无明显强化;18例呈低及稍高信号混杂,无明显强化或延迟轻度强化;4例以稍高信号或高信号为主,夹杂斑点、编织索条影,增强斑点、索条影强化明显,余部无明显强化或略强化;4例呈等及稍高信号、DWI上明显高信号,增强明显强化。4例囊实性肿块囊性成分囊壁略强化。22例检出腹水,大量腹水6例。病理结果 :32例均为良性。肿瘤形态同MRI表现,包膜均完整。4例表现出囊实性,32例实性瘤或实性成分剖面呈灰黄色或灰白色或黄白交织。镜下,瘤细胞呈梭形,有网状纤维包绕,且出现大的形变细胞核。术中22例有腹水,大量腹水6例。MRI与病理表现相比,差异无统计学意义。结论卵巢纤维-卵泡膜细胞瘤MR表现为边缘清楚的类圆形、椭圆形、较大的可为哑铃形或分叶状的实性或囊实性肿块。实性肿块或实性成分典型表现为T2WI上及T1WI上为低信号,增强无强化或轻度延迟强化;非典型表现T2WI上信号多样化,随卵泡膜细胞成分增多,信号增高,T1WI增强强化成分逐渐增多;囊性部分仅囊壁略强化。这些特点有助于提高对卵巢纤维卵泡膜细胞瘤的认识和诊断水平,MRI可以反映病理特征。 展开更多
关键词 卵巢纤维-卵泡膜细胞瘤 mri 病理表现
下载PDF
成年型卵巢颗粒细胞瘤的MRI表现
15
作者 吴志羡 张飞鹏 林伟华 《中外医疗》 2016年第16期30-33,共4页
目的评价成年型卵巢颗粒细胞瘤的MRI表现及其与病理的情况,以期提高其诊断水平。方法方便选取该院2009年7月—2015年4月经术后病理证实的15例卵巢颗粒细胞瘤的临床资料及MRI表现,观察肿块内部信号、强化特点、囊变情况及肿块大小与囊变... 目的评价成年型卵巢颗粒细胞瘤的MRI表现及其与病理的情况,以期提高其诊断水平。方法方便选取该院2009年7月—2015年4月经术后病理证实的15例卵巢颗粒细胞瘤的临床资料及MRI表现,观察肿块内部信号、强化特点、囊变情况及肿块大小与囊变程度的关系等。结果 15例肿块均单侧发生,10个呈囊实性,3个呈多房囊性,2个呈实性。10个囊液内合并出血。随着肿块增大肿块囊变程度越高。结论卵巢颗粒细胞瘤MRI信号表现具有一定特征性,对于成年型卵巢颗粒细胞瘤诊断与鉴别诊断具有重要价值。 展开更多
关键词 卵巢 颗粒细胞瘤 mri 病理
下载PDF
卵巢颗粒细胞瘤的MDCT及MRI特征性表现 被引量:8
16
作者 王海亮 阮圆 +3 位作者 周冰 黎良山 诸葛岚 金丽清 《医学影像学杂志》 2019年第5期814-818,共5页
目的探讨卵巢颗粒细胞瘤(OGCT)的MDCT及MRI表现,以期提高对此类肿瘤的认识及诊断水平。方法回顾性分析23例经病理证实的OGCT的临床资料及MDCT/MRI表现,6例行MDCT扫描,17例行MRI扫描,总结OGCT影像学特点。结果成人型卵巢颗粒细胞瘤(OAGCT... 目的探讨卵巢颗粒细胞瘤(OGCT)的MDCT及MRI表现,以期提高对此类肿瘤的认识及诊断水平。方法回顾性分析23例经病理证实的OGCT的临床资料及MDCT/MRI表现,6例行MDCT扫描,17例行MRI扫描,总结OGCT影像学特点。结果成人型卵巢颗粒细胞瘤(OAGCT)19例,其中3例为复发病例;幼稚型卵巢颗粒细胞瘤(OJGCT)4例。23例病灶均为单发;病灶最大径平均值(10.0±4.2)cm。发生于左侧附件18例,右侧附件5例。实性肿块4例,囊实性肿块19例。CT平扫肿块实性部分表现为等或稍低密度,其中2例见斑点状钙化;增强扫描2例肿块实性部分轻中度强化,2例呈明显强化,并见肿瘤内部及边缘“蚯蚓”状迂曲血管影。MRI检查中13例肿块实性部分T2WI压脂像呈稍高信号,T1WI呈等或稍低信号,DWI呈不均匀性高信号;4例OJGCT“囊中囊”的实性部分T1WI及T2WI均呈高信号,DWI呈环形高信号(“靶征”)。增强扫描肿块实性部分呈明显渐进性强化,囊性部分不强化。5例肿块呈“蜂窝征”及4例呈“海绵征”;2例肿块呈“哑铃状”生长,局部见“束腰征”。结论OGCT的MDCT/MRI表现具有一定特征性,特别是OJGCT的“囊中囊”及“靶征”对此病诊断及鉴别诊断具有重要意义。 展开更多
关键词 卵巢颗粒细胞瘤 卵巢 体层摄影术 X线计算机 磁共振成像
下载PDF
卵巢少见原发肿瘤的临床特点及MRI征象对比 被引量:1
17
作者 马佳琪 梁秀芬 +6 位作者 戴强 闫斌 王茵 申甜 杨雪梅 田小飞 袁勇 《现代肿瘤医学》 CAS 2016年第23期3809-3814,共6页
目的:探讨几种卵巢原发少见肿瘤的临床及MRI特点,提高该类病变的诊断准确率。方法:回顾性研究45例经手术病理证实的卵巢少见原发肿瘤的临床及术前MRI资料。结果:45例卵巢肿瘤患者48处肿块,单侧病灶42例,双侧病灶共3例,包括卵巢子宫内膜... 目的:探讨几种卵巢原发少见肿瘤的临床及MRI特点,提高该类病变的诊断准确率。方法:回顾性研究45例经手术病理证实的卵巢少见原发肿瘤的临床及术前MRI资料。结果:45例卵巢肿瘤患者48处肿块,单侧病灶42例,双侧病灶共3例,包括卵巢子宫内膜样腺癌12例,透明细胞癌6例,颗粒细胞瘤8例,卵泡膜细胞瘤10例,纤维瘤9例;患者多数见于围绝经期及绝经后女性,临床表现多样,上皮样肿瘤可见CA125升高及部分CEA升高,颗粒细胞瘤及卵泡膜细胞瘤可出现雌激素增高及相关依赖症状,纤维瘤症状轻微;MRI平扫卵巢肿块多为囊实性,实性肿块次之,但病灶内成分及信号存在差异,增强扫描强化特点及DWI信号各异,有助于提高诊断率。结论:几种卵巢少见肿瘤的临床表现及MRI征象具有一定的差异性,综合应用对肿瘤的定性诊断有重要的临床价值。 展开更多
关键词 卵巢子宫内膜样腺癌 透明细胞癌 颗粒细胞瘤 卵泡膜细胞瘤 纤维瘤 mri 临床特点
下载PDF
卵巢卵泡膜细胞瘤的CT、MRI诊断分析 被引量:1
18
作者 陈妙勤 《中外医疗》 2015年第25期195-196,共2页
目的探讨卵巢卵泡膜细胞瘤的CT、MRI的影像表现特征。方法回顾性分析2010年2月—2015年2月该院经病理证实的58例卵巢卵泡膜细胞瘤患者的CT、MRI检查的影像学表现。结果 23例CT检查患者中,实性肿瘤占73.9%;平扫密度均匀者占87.0%,增强扫... 目的探讨卵巢卵泡膜细胞瘤的CT、MRI的影像表现特征。方法回顾性分析2010年2月—2015年2月该院经病理证实的58例卵巢卵泡膜细胞瘤患者的CT、MRI检查的影像学表现。结果 23例CT检查患者中,实性肿瘤占73.9%;平扫密度均匀者占87.0%,增强扫描呈轻度强化。35例MRI检查患者中,实性肿瘤占74.3%;实性为主肿块T1WI和T2WI呈等信号或低信号为主;增强扫描轻度强化。结论 CT和MRI对卵巢卵泡膜细胞瘤的诊断有一定特征性,可结合临床相关检查,以明确该病的诊断。 展开更多
关键词 卵巢卵泡膜细胞瘤 CT mri
下载PDF
卵巢幼年性粒层细胞瘤伴Maffucci综合征 被引量:7
19
作者 袁键群 林小娜 +2 位作者 许敬尧 祝佳 郑伟良 《临床与实验病理学杂志》 CAS CSCD 2003年第4期364-367,共4页
目的 探讨幼年性粒层细胞瘤和Maffucci综合征的临床病理特征及两者伴发的原因。方法 对 1例伴Maffucci综合征的幼年性粒层细胞瘤进行HE、组织化学及免疫组织化学染色观察 ,并复习文献。结果 幼年性粒层细胞瘤多发生于 2 0岁以下患者 ... 目的 探讨幼年性粒层细胞瘤和Maffucci综合征的临床病理特征及两者伴发的原因。方法 对 1例伴Maffucci综合征的幼年性粒层细胞瘤进行HE、组织化学及免疫组织化学染色观察 ,并复习文献。结果 幼年性粒层细胞瘤多发生于 2 0岁以下患者 ,儿童患者常表现为青春期前假性性早熟 ,生育期妇女常表现为月经紊乱。组织学上具特征性滤泡结构 ,丰富的嗜酸性或空泡化胞质 ,无核沟及Call Exner小体 ,核分裂象多见。Inhibin免疫组化染色有助于诊断和鉴别诊断。Maffucci综合征为先天性软骨发育异常 ,易合并恶性肿瘤。 14例卵巢幼年性粒层细胞瘤伴Maffucci综合征或Ollier病中卵巢肿瘤和骨病变有同侧分布倾向。 展开更多
关键词 卵巢 幼年性粒层细胞瘤 MAFFUCCI综合征 免疫组织化学 肿瘤
下载PDF
儿童卵巢颗粒细胞瘤CT及临床表现 被引量:6
20
作者 陶然 杨梅 +3 位作者 袁新宇 杨洋 郭红伟 刘海霞 《中国医学影像技术》 CSCD 北大核心 2019年第6期882-885,共4页
目的分析儿童卵巢颗粒细胞瘤的CT特征及临床表现。方法回顾性分析经病理证实的12例女性卵巢颗粒细胞瘤患儿的术前CT和相关临床表现,观察卵巢肿物的性质、大小、钙化、强化程度、有无瘤内血管、子宫大小、盆腔积液及增大淋巴结等影像学... 目的分析儿童卵巢颗粒细胞瘤的CT特征及临床表现。方法回顾性分析经病理证实的12例女性卵巢颗粒细胞瘤患儿的术前CT和相关临床表现,观察卵巢肿物的性质、大小、钙化、强化程度、有无瘤内血管、子宫大小、盆腔积液及增大淋巴结等影像学特征。结果12例卵巢颗粒细胞瘤患儿以腹痛、性早熟或男性化等相关症状就诊;9例术前血清雌二醇水平升高,2例血清睾酮水平升高。CT平扫表现为实性肿物2例、囊实性8例、囊性肿物2例,长径中位数为82.50(46.75,111.00)mm;肿瘤内钙化1例;盆腔内大量积液2例,子宫增大9例。增强扫描肿物实性成分明显强化,9例内见纡曲血管影,囊性肿物均无明显强化;未见淋巴结明显增大。结论结合特异性内分泌症状及相关激素水平、肿瘤标记物改变,CT发现儿童血供丰富的卵巢肿物、伴子宫体积增大高度提示卵巢颗粒细胞瘤。 展开更多
关键词 儿童 卵巢肿瘤 粒层细胞瘤 体层摄影术 X线计算机
下载PDF
上一页 1 2 4 下一页 到第
使用帮助 返回顶部