目的观察双相躁狂患者血浆中GRM-7 m RNA的表达水平的改变及与双相躁狂之间的关系。方法将105例双相障碍躁狂发作患者设为患者组,100例与患者组在年龄和性别上匹配的健康志愿者设为对照组。患者组常规应用碳酸锂治疗,观察1个月,患者组...目的观察双相躁狂患者血浆中GRM-7 m RNA的表达水平的改变及与双相躁狂之间的关系。方法将105例双相障碍躁狂发作患者设为患者组,100例与患者组在年龄和性别上匹配的健康志愿者设为对照组。患者组常规应用碳酸锂治疗,观察1个月,患者组于入组时和治疗1个月时、对照组于入组时,分别评定BRMS量表并收集血浆,采用实时荧光定量PCR技术检测GRM-7 m RNA的表达水平,最后对检测结果及BRMS评分进行统计分析。结果患者组血浆GRM-7 m RNA表达显著低于对照组(P<0.001);治疗1个月后,患者组血浆GRM-7m RNA的表达水平显著升高(P<0.001)。结论血浆GRM-7 m RNA的表达水平和双相障碍躁狂发作有关。展开更多
Applying the modeling method of Grey system and accumulated generating operation of reciprocal number for the problem of lower precision as well as lower adaptability in non-equidistant GM (1, 1) model, the calculatio...Applying the modeling method of Grey system and accumulated generating operation of reciprocal number for the problem of lower precision as well as lower adaptability in non-equidistant GM (1, 1) model, the calculation formulas were deduced and a non-equidistant GRM (1, 1) model generated by accumulated generating operation of reciprocal number was put forward .The grey GRM (1, 1) model can be used in non-equal interval & equal interval time series and has the characteristic of high precision as well as high adaptability. Example validates the practicability and reliability of the proposed model.展开更多
Aiming the problem of low accuracy during establishing grey model in which monotonically decreasing sequence data and traditional modeling methods are used, this paper applied the reciprocal accumulated generating and...Aiming the problem of low accuracy during establishing grey model in which monotonically decreasing sequence data and traditional modeling methods are used, this paper applied the reciprocal accumulated generating and the approach optimizing grey derivative which is based on three points to deduce the calculation formulas for model parameters, established grey GRM(1, 1) model based on reciprocal accumulated generating. It provides a new method for the grey modeling. The example validates the practicability and reliability of the proposed model.展开更多
文摘目的观察双相躁狂患者血浆中GRM-7 m RNA的表达水平的改变及与双相躁狂之间的关系。方法将105例双相障碍躁狂发作患者设为患者组,100例与患者组在年龄和性别上匹配的健康志愿者设为对照组。患者组常规应用碳酸锂治疗,观察1个月,患者组于入组时和治疗1个月时、对照组于入组时,分别评定BRMS量表并收集血浆,采用实时荧光定量PCR技术检测GRM-7 m RNA的表达水平,最后对检测结果及BRMS评分进行统计分析。结果患者组血浆GRM-7 m RNA表达显著低于对照组(P<0.001);治疗1个月后,患者组血浆GRM-7m RNA的表达水平显著升高(P<0.001)。结论血浆GRM-7 m RNA的表达水平和双相障碍躁狂发作有关。
文摘Applying the modeling method of Grey system and accumulated generating operation of reciprocal number for the problem of lower precision as well as lower adaptability in non-equidistant GM (1, 1) model, the calculation formulas were deduced and a non-equidistant GRM (1, 1) model generated by accumulated generating operation of reciprocal number was put forward .The grey GRM (1, 1) model can be used in non-equal interval & equal interval time series and has the characteristic of high precision as well as high adaptability. Example validates the practicability and reliability of the proposed model.
文摘Aiming the problem of low accuracy during establishing grey model in which monotonically decreasing sequence data and traditional modeling methods are used, this paper applied the reciprocal accumulated generating and the approach optimizing grey derivative which is based on three points to deduce the calculation formulas for model parameters, established grey GRM(1, 1) model based on reciprocal accumulated generating. It provides a new method for the grey modeling. The example validates the practicability and reliability of the proposed model.
