Prenatal and postnatal period presents the highest prevalence of mental disorders in women's lives and depression is the most frequent one,affecting approximately one in every five mothers.The aggravating factor h...Prenatal and postnatal period presents the highest prevalence of mental disorders in women's lives and depression is the most frequent one,affecting approximately one in every five mothers.The aggravating factor here is that during this period psychiatric symptoms affect not only women's health and well-being but may also interfere in the infant's intra and extra-uterine development.Although the causes of the relationship between maternal mental disorders and possible risks to a child's health and development remain unknown,it is suspected that these risks may be related to the use of psychotropic drugs during pregnancy,to substance abuse and the mother's lifestyle.Moreover,after delivery,maternal mental disorders may also impair the ties of affection(bonding) with the newborn and the ma-ternal capacity of caring in the post-partum period thus increasing the risk for infant infection and malnutrition,impaired child growth that is expressed in low weight and height for age,and even behavioral problems and vulnerability to presenting mental disorders in adulthood.Generally speaking,research on this theme can be divided into the type of mental disorder analyzed: studies that research minor mental disorders during pregnancy such as depression and anxiety find an association between these maternal disorders and obstetric complications such as prematurity and low birth weight,whereas studies that evaluate severe maternal mental disorders such as schizophrenia and bipolar disorder have found not only an association with general obstetric complications as well as with congenital malformations and perinatal mortality.Therefore,the success of infant growth care programs also depends on the mother's mental well being.Such findings have led to the need for new public policies in the field of maternal-infant care geared toward the population of mothers.However,more research is necessary so as to confirm the association between all factors with greater scientific rigor.展开更多
<strong>Objective:</strong><span style="font-family:""><span style="font-family:Verdana;"> To present the results of a pilot study that evaluated the psycho-emotional w...<strong>Objective:</strong><span style="font-family:""><span style="font-family:Verdana;"> To present the results of a pilot study that evaluated the psycho-emotional well-being, and the perinatal results of a group of 44 women who attended a prenatal program that incorporates playful and educational activities, in a Child Development Center in Durango. Mexico. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A group of 44 women with informed consent participated for 28 weeks in the prenatal program. The condition of psycho-emotional well-being during the first and third trimesters and the perinatal results were analyzed with validated instruments. Physiological stress was also assessed with salivary cortisol in the same trimesters. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> More than 90% of the women evaluated their psycho-emotional condition as satisfactory and very satisfactory. The evaluation of anxiety in its Trait/State modalities placed the participants in the category of mild and moderate. Salivary cortisol showed values within a normal range. Perinatal results showed that 98% of deliveries were at term, 93% of newborns weighed more than 2500 grams, and 98% of newborns had an APGAR score of 9 at 5 minutes. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The results suggest that the incorporation of playful and educational actions to prenatal surveillance positively influenced the biopsychosocial condition of the pregnant woman and favorable perinatal outcomes.</span></span>展开更多
BACKGROUND Data that assess maternal and infant outcomes in hepatitis C virus(HCV)-infected mothers are limited.AIM To investigate the frequency of complications and the associated risk factors.METHODS We performed a ...BACKGROUND Data that assess maternal and infant outcomes in hepatitis C virus(HCV)-infected mothers are limited.AIM To investigate the frequency of complications and the associated risk factors.METHODS We performed a cohort study to compare pregnancy and fetal outcomes of HCVviremic mothers with those of healthy mothers.Risk factors were analyzed with logistic regression.RESULTS Among 112 consecutive HCV antibody-positive mothers screened,we enrolled 79 viremic mothers.We randomly selected 115 healthy mothers from the birth registry as the control.Compared to healthy mothers,HCV mothers had a significantly higher frequency of anemia[2.6%(3/115)vs 19.0%(15/79),P<0.001]during pregnancy,medical conditions that required caesarian section[27.8%(32/115)vs 48.1%(38/79),P=0.004],and nuchal cords[9.6%(11/115)vs 34.2%(27/79),P<0.001].In addition,the mean neonatal weight in the HCV group was significantly lower(3278.3±462.0 vs 3105.1±459.4 gms;P=0.006),and the mean head circumference was smaller(33.3±0.6 vs 33.1±0.7 cm;P=0.03).In a multivariate model,HCV-infected mothers were more likely to suffer anemia[adjusted odds ratio(OR):18.1,95%confidence interval(CI):4.3-76.6],require caesarian sections(adjusted OR:2.6,95%CI:1.4-4.9),and have nuchal cords(adjusted OR:5.6,95%CI:2.4-13.0).Their neonates were also more likely to have smaller head circumferences(adjusted OR:2.1,95%CI:1.1-4.3)and lower birth weights than the average(≤3250 gms)with an adjusted OR of 2.2(95%CI:1.2-4.0).The vertical transmission rate was 1%in HCV-infected mothers.CONCLUSION Maternal HCV infections may associate with pregnancy and obstetric complications.We demonstrated a previously unreported association between maternal HCV viremia and a smaller neonatal head circumference,suggesting fetal growth restriction.展开更多
目的:分析瘢痕子宫合并妊娠期甲状腺功能减退症(甲减)对妊娠结局与母婴健康状况的影响。方法:回顾性分析暨南大学附属顺德医院妇产科2021年2月-2022年2月收治的300例分娩产妇,其中瘢痕子宫合并妊娠期甲减孕产妇100例(A组)、单纯瘢痕子...目的:分析瘢痕子宫合并妊娠期甲状腺功能减退症(甲减)对妊娠结局与母婴健康状况的影响。方法:回顾性分析暨南大学附属顺德医院妇产科2021年2月-2022年2月收治的300例分娩产妇,其中瘢痕子宫合并妊娠期甲减孕产妇100例(A组)、单纯瘢痕子宫孕产妇100例(B组)、单纯妊娠期甲减孕产妇100例(C组),分析三组孕产妇的甲状腺功能、分娩结局及母婴结局。结果:A组游离四碘甲状腺原氨酸(FT4)、促甲状腺激素(TSH)、甲状腺过氧化物酶抗体(TPO-Ab)水平均高于C组、B组,且三组FT4、TSH、TPO-Ab水平对比,差异均有统计学意义(P<0.05)。A组住院时间、总产程时间均长于B组、C组,B组剖宫产率低于C组、A组,差异均有统计学意义(P<0.05)。B组胎儿宫内窘迫发生率、新生儿体重均低于C组、A组,A组新生儿出生后5 min Apgar评分低于B组、C组(P<0.05),B组妊娠期糖尿病、妊娠期高血压、贫血发病率均低于C组、A组,差异均有统计学意义(P<0.05)。结论:瘢痕子宫合并妊娠期甲减疾病不利于母婴健康,重点在于监测,防范风险。展开更多
基金Supported by Brazil Higher Education Consortia Program(CAPES).
文摘Prenatal and postnatal period presents the highest prevalence of mental disorders in women's lives and depression is the most frequent one,affecting approximately one in every five mothers.The aggravating factor here is that during this period psychiatric symptoms affect not only women's health and well-being but may also interfere in the infant's intra and extra-uterine development.Although the causes of the relationship between maternal mental disorders and possible risks to a child's health and development remain unknown,it is suspected that these risks may be related to the use of psychotropic drugs during pregnancy,to substance abuse and the mother's lifestyle.Moreover,after delivery,maternal mental disorders may also impair the ties of affection(bonding) with the newborn and the ma-ternal capacity of caring in the post-partum period thus increasing the risk for infant infection and malnutrition,impaired child growth that is expressed in low weight and height for age,and even behavioral problems and vulnerability to presenting mental disorders in adulthood.Generally speaking,research on this theme can be divided into the type of mental disorder analyzed: studies that research minor mental disorders during pregnancy such as depression and anxiety find an association between these maternal disorders and obstetric complications such as prematurity and low birth weight,whereas studies that evaluate severe maternal mental disorders such as schizophrenia and bipolar disorder have found not only an association with general obstetric complications as well as with congenital malformations and perinatal mortality.Therefore,the success of infant growth care programs also depends on the mother's mental well being.Such findings have led to the need for new public policies in the field of maternal-infant care geared toward the population of mothers.However,more research is necessary so as to confirm the association between all factors with greater scientific rigor.
文摘<strong>Objective:</strong><span style="font-family:""><span style="font-family:Verdana;"> To present the results of a pilot study that evaluated the psycho-emotional well-being, and the perinatal results of a group of 44 women who attended a prenatal program that incorporates playful and educational activities, in a Child Development Center in Durango. Mexico. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A group of 44 women with informed consent participated for 28 weeks in the prenatal program. The condition of psycho-emotional well-being during the first and third trimesters and the perinatal results were analyzed with validated instruments. Physiological stress was also assessed with salivary cortisol in the same trimesters. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> More than 90% of the women evaluated their psycho-emotional condition as satisfactory and very satisfactory. The evaluation of anxiety in its Trait/State modalities placed the participants in the category of mild and moderate. Salivary cortisol showed values within a normal range. Perinatal results showed that 98% of deliveries were at term, 93% of newborns weighed more than 2500 grams, and 98% of newborns had an APGAR score of 9 at 5 minutes. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The results suggest that the incorporation of playful and educational actions to prenatal surveillance positively influenced the biopsychosocial condition of the pregnant woman and favorable perinatal outcomes.</span></span>
基金Supported by The Ministry of Science and Technology of China for the National Five-Year Key Projects in Infectious Diseases,No. 2015ZX10004801
文摘BACKGROUND Data that assess maternal and infant outcomes in hepatitis C virus(HCV)-infected mothers are limited.AIM To investigate the frequency of complications and the associated risk factors.METHODS We performed a cohort study to compare pregnancy and fetal outcomes of HCVviremic mothers with those of healthy mothers.Risk factors were analyzed with logistic regression.RESULTS Among 112 consecutive HCV antibody-positive mothers screened,we enrolled 79 viremic mothers.We randomly selected 115 healthy mothers from the birth registry as the control.Compared to healthy mothers,HCV mothers had a significantly higher frequency of anemia[2.6%(3/115)vs 19.0%(15/79),P<0.001]during pregnancy,medical conditions that required caesarian section[27.8%(32/115)vs 48.1%(38/79),P=0.004],and nuchal cords[9.6%(11/115)vs 34.2%(27/79),P<0.001].In addition,the mean neonatal weight in the HCV group was significantly lower(3278.3±462.0 vs 3105.1±459.4 gms;P=0.006),and the mean head circumference was smaller(33.3±0.6 vs 33.1±0.7 cm;P=0.03).In a multivariate model,HCV-infected mothers were more likely to suffer anemia[adjusted odds ratio(OR):18.1,95%confidence interval(CI):4.3-76.6],require caesarian sections(adjusted OR:2.6,95%CI:1.4-4.9),and have nuchal cords(adjusted OR:5.6,95%CI:2.4-13.0).Their neonates were also more likely to have smaller head circumferences(adjusted OR:2.1,95%CI:1.1-4.3)and lower birth weights than the average(≤3250 gms)with an adjusted OR of 2.2(95%CI:1.2-4.0).The vertical transmission rate was 1%in HCV-infected mothers.CONCLUSION Maternal HCV infections may associate with pregnancy and obstetric complications.We demonstrated a previously unreported association between maternal HCV viremia and a smaller neonatal head circumference,suggesting fetal growth restriction.
文摘目的:分析瘢痕子宫合并妊娠期甲状腺功能减退症(甲减)对妊娠结局与母婴健康状况的影响。方法:回顾性分析暨南大学附属顺德医院妇产科2021年2月-2022年2月收治的300例分娩产妇,其中瘢痕子宫合并妊娠期甲减孕产妇100例(A组)、单纯瘢痕子宫孕产妇100例(B组)、单纯妊娠期甲减孕产妇100例(C组),分析三组孕产妇的甲状腺功能、分娩结局及母婴结局。结果:A组游离四碘甲状腺原氨酸(FT4)、促甲状腺激素(TSH)、甲状腺过氧化物酶抗体(TPO-Ab)水平均高于C组、B组,且三组FT4、TSH、TPO-Ab水平对比,差异均有统计学意义(P<0.05)。A组住院时间、总产程时间均长于B组、C组,B组剖宫产率低于C组、A组,差异均有统计学意义(P<0.05)。B组胎儿宫内窘迫发生率、新生儿体重均低于C组、A组,A组新生儿出生后5 min Apgar评分低于B组、C组(P<0.05),B组妊娠期糖尿病、妊娠期高血压、贫血发病率均低于C组、A组,差异均有统计学意义(P<0.05)。结论:瘢痕子宫合并妊娠期甲减疾病不利于母婴健康,重点在于监测,防范风险。
