As nonclassical nucleic acid structures,G-quadruplexes(G4s)not only play important roles in gene regulation and stability maintenance,but are also widely used in nanotechnology.Structural diversity is one of the main ...As nonclassical nucleic acid structures,G-quadruplexes(G4s)not only play important roles in gene regulation and stability maintenance,but are also widely used in nanotechnology.Structural diversity is one of the main factors explaining the popularity of G4s,but a comprehensive and integrated study of different factors determining G4 structural versatility is currently lacking.展开更多
基金supported in part by the National Natural Science Foundation of China(nos.21977045 and 21635005)the Fundamental Research Funds for the Central Universities(no.02051430210)+2 种基金the funds of Nanjing University(no.020514912216)project 21-23718S of the Czech Science Foundation(P.S.and J.S.)the project SYMBIT reg.number:CZ.02.1.01/0.0/0.0/15_003/0000477 financed by the ERDF(J.S.and J.-L.M.).
文摘As nonclassical nucleic acid structures,G-quadruplexes(G4s)not only play important roles in gene regulation and stability maintenance,but are also widely used in nanotechnology.Structural diversity is one of the main factors explaining the popularity of G4s,but a comprehensive and integrated study of different factors determining G4 structural versatility is currently lacking.