It was proposed that park planning should be based on local economic development,should focus on the preservation of primitive ecological conditions and the application of low-carbon and energy-saving concepts.The pla...It was proposed that park planning should be based on local economic development,should focus on the preservation of primitive ecological conditions and the application of low-carbon and energy-saving concepts.The planning of Ancient Banyan Park in Mengshan County by following the principles of respecting local history and culture,improving functions and supporting facilities,human-centered,overall planning and all-around consideration,respecting characteristics of the local area(the planning site),satisfying operation requirements of the park,applying low-carbon and energy-saving concepts,and avoiding over-engineering,aimed at protecting natural images of the park,primitive history,culture and characteristics of the local area and providing a space for local residents' various activities.Modern aesthetic forms were combined,cultural connotation of natural environment stressed to build a landscape space system of the Ancient Banyan Park that matches well with environment of the planning site.The park was designed into 4 functional areas:sport area,fitness plaza area,garden recreational area and ancient banyan cultural area.Different functions of these subareas were taken into consideration to create conservation-minded garden landscapes which were both independent and unified.展开更多
With the continuous development of gold ore prospecting and exploration in recent years a new type of micro-disseminated gold deposits have been found in the regions of Southwest Guizhou Province and Northwest Guangxi...With the continuous development of gold ore prospecting and exploration in recent years a new type of micro-disseminated gold deposits have been found in the regions of Southwest Guizhou Province and Northwest Guangxi Zhuang Autonomous Region,with the orebodies directly occurring in diabase or in the contact zone between diabase and strata.The orebodies are strictly controlled by fault structures.The discovery of this type of gold deposits has brought about new prospects for gold ore prospecting in the Yunnan-Guizhou-Guangxi Golden Triangle region.From the preliminary analysis of the geological characteristics of the Qiaoxiang gold deposit in Wangmo County,in combination with the results of research work in the adjacent areas in recent years,this paper roughly described the geological characteristics and metallogenic conditions of this type of gold ore deposits with an attempt to make more and more geologists pay enough attention to this type of gold ore deposits,so as to promote gold ore prospecting in Guizhou Province to develop toward a variety of types of gold deposits in all round way.展开更多
Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from b...Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from both academia and industry.However,the extensive literature that exists on this topic does not address identifying the severity of actuator faults and focuses mainly on actuator fault detection and isolation.In addition,previous studies of actuator fault identification have not dealt with multiple concurrent faults in real time,especially when these are accompanied by sudden failures under dynamic conditions.This study develops component-level models for fault identification in four typical actuators used in high-bypass ratio turbofan engines under both dynamic and steady-state conditions and these are then integrated with the engine performance model developed by the authors.The research results reported here present a novel method of quantifying actuator faults using dynamic effect compensation.The maximum error for each actuator is less than0.06%and 0.07%,with average computational time of less than 0.0058 s and 0.0086 s for steady-state and transient cases,respectively.These results confirm that the proposed method can accurately and efficiently identify concurrent actuator fault for an engine operating under either transient or steady-state conditions,even in the case of a sudden malfunction.The research results emonstrate the potential benefit to emergency response capabilities by introducing this method of monitoring the health of aero engines.展开更多
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may...Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.展开更多
Federated learning(FL)is a distributed machine learning paradigm for edge cloud computing.FL can facilitate data-driven decision-making in tactical scenarios,effectively addressing both data volume and infrastructure ...Federated learning(FL)is a distributed machine learning paradigm for edge cloud computing.FL can facilitate data-driven decision-making in tactical scenarios,effectively addressing both data volume and infrastructure challenges in edge environments.However,the diversity of clients in edge cloud computing presents significant challenges for FL.Personalized federated learning(pFL)received considerable attention in recent years.One example of pFL involves exploiting the global and local information in the local model.Current pFL algorithms experience limitations such as slow convergence speed,catastrophic forgetting,and poor performance in complex tasks,which still have significant shortcomings compared to the centralized learning.To achieve high pFL performance,we propose FedCLCC:Federated Contrastive Learning and Conditional Computing.The core of FedCLCC is the use of contrastive learning and conditional computing.Contrastive learning determines the feature representation similarity to adjust the local model.Conditional computing separates the global and local information and feeds it to their corresponding heads for global and local handling.Our comprehensive experiments demonstrate that FedCLCC outperforms other state-of-the-art FL algorithms.展开更多
The focusing modified Korteweg-de Vries(mKdV)equation with multiple high-order poles under the nonzero boundary conditions is first investigated via developing a Riemann-Hilbert(RH)approach.We begin with the asymptoti...The focusing modified Korteweg-de Vries(mKdV)equation with multiple high-order poles under the nonzero boundary conditions is first investigated via developing a Riemann-Hilbert(RH)approach.We begin with the asymptotic property,symmetry and analyticity of the Jost solutions,and successfully construct the RH problem of the focusing mKdV equation.We solve the RH problem when 1/S_(11)(k)has a single highorder pole and multiple high-order poles.Furthermore,we derive the soliton solutions of the focusing mKdV equation which corresponding with a single high-order pole and multiple high-order poles,respectively.Finally,the dynamics of one-and two-soliton solutions are graphically discussed.展开更多
To realize carbon neutrality,there is an urgent need to develop sustainable,green energy systems(especially solar energy systems)owing to the environmental friendliness of solar energy,given the substantial greenhouse...To realize carbon neutrality,there is an urgent need to develop sustainable,green energy systems(especially solar energy systems)owing to the environmental friendliness of solar energy,given the substantial greenhouse gas emissions from fossil fuel-based power sources.When it comes to the evolution of intelligent green energy systems,Internet of Things(IoT)-based green-smart photovoltaic(PV)systems have been brought into the spotlight owing to their cutting-edge sensing and data-processing technologies.This review is focused on three critical segments of IoT-based green-smart PV systems.First,the climatic parameters and sensing technologies for IoT-based PV systems under extreme weather conditions are presented.Second,the methods for processing data from smart sensors are discussed,in order to realize health monitoring of PV systems under extreme environmental conditions.Third,the smart materials applied to sensors and the insulation materials used in PV backsheets are susceptible to aging,and these materials and their aging phenomena are highlighted in this review.This review also offers new perspectives for optimizing the current international standards for green energy systems using big data from IoT-based smart sensors.展开更多
Automated pavement condition survey is of critical importance to road network management.There are three primary tasks involved in pavement condition surveys,namely data collection,data processing and condition evalua...Automated pavement condition survey is of critical importance to road network management.There are three primary tasks involved in pavement condition surveys,namely data collection,data processing and condition evaluation.Artificial intelligence(AI)has achieved many breakthroughs in almost every aspect of modern technology over the past decade,and undoubtedly offers a more robust approach to automated pavement condition survey.This article aims to provide a comprehensive review on data collection systems,data processing algorithms and condition evaluation methods proposed between 2010 and 2023 for intelligent pavement condition survey.In particular,the data collection system includes AI-driven hardware devices and automated pavement data collection vehicles.The AI-driven hardware devices including right-of-way(ROW)cameras,ground penetrating radar(GPR)devices,light detection and ranging(LiDAR)devices,and advanced laser imaging systems,etc.These different hardware components can be selectively mounted on a vehicle to simultaneously collect multimedia information about the pavement.In addition,this article pays close attention to the application of artificial intelligence methods in detecting pavement distresses,measuring pavement roughness,identifying pavement rutting,analyzing skid resistance and evaluating structural strength of pavements.Based upon the analysis of a variety of the state-of-the-art artificial intelligence methodologies,remaining challenges and future needs with respect to intelligent pavement condition survey are discussed eventually.展开更多
Laminated composites are widely used in many engineering industries such as aircraft, spacecraft, boat hulls, racing car bodies, and storage tanks. We analyze the 3D deformations of a multilayered, linear elastic, ani...Laminated composites are widely used in many engineering industries such as aircraft, spacecraft, boat hulls, racing car bodies, and storage tanks. We analyze the 3D deformations of a multilayered, linear elastic, anisotropic rectangular plate subjected to arbitrary boundary conditions on one edge and simply supported on other edge. The rectangular laminate consists of anisotropic and homogeneous laminae of arbitrary thicknesses. This study presents the elastic analysis of laminated composite plates subjected to sinusoidal mechanical loading under arbitrary boundary conditions. Least square finite element solutions for displacements and stresses are investigated using a mathematical model, called a state-space model, which allows us to simultaneously solve for these field variables in the composite structure’s domain and ensure that continuity conditions are satisfied at layer interfaces. The governing equations are derived from this model using a numerical technique called the least-squares finite element method (LSFEM). These LSFEMs seek to minimize the squares of the governing equations and the associated side conditions residuals over the computational domain. The model is comprised of layerwise variables such as displacements, out-of-plane stresses, and in- plane strains, treated as independent variables. Numerical results are presented to demonstrate the response of the laminated composite plates under various arbitrary boundary conditions using LSFEM and compared with the 3D elasticity solution available in the literature.展开更多
Microseismic event location is one of the core parameters in microseismic monitoring,and the accuracy of localization will directly affect the effectiveness of engineering applications.However,limited by spatial facto...Microseismic event location is one of the core parameters in microseismic monitoring,and the accuracy of localization will directly affect the effectiveness of engineering applications.However,limited by spatial factors,the geometry of the sensor installation will be close to linear,which makes the localization equation suffer from the pathological problem,and the localization accuracy is greatly reduced.To address this problem,the reasons for the pathological problem are analyzed from the perspective of the objective function residuals and coefficient matrix.The pathological problem is caused by the combined effect of the poorer sensor array and data errors,and its residual isosurface shows a conical distribution,and as the residual value decreases,the apex of the isosurface gradually extends to the far side,and the localization results do not converge.For this reason,an improved regularized Newton downhill localization algorithm is proposed.In this method,firstly,the Newtonian downhill method is improved so that the magnitudes of the seismic source parameters are the same,and the condition number of the coefficient matrix is reduced;then,the L-curve method is used to calculate the regularization factor for the pathological equations,and the coefficient matrix is improved;finally,the pathological equations are regularized,and the seismic source coordinates are obtained by the improved Newtonian downhill method.The results of engineering applications show that compared with the traditional algorithm based on automatic of P-arrival picking,the number of effective microseismic events calculated by the proposed localization algorithm is increased by 194.7%,and the localization accuracy is substantially improved.The proposed algorithm reduces the problem of low accuracy of S-arrival picking and allows localization using only P-wave arrival.The method reduces the quality requirements of the data and significantly improves the utilization of microseismic events and positioning accuracy.展开更多
Dolichospermum spp.and Microcystis spp.are two common cyanobacteria that form blooms in the Changjiang(Yangtze)River basin,but the environmental conditions for their succession in large lakes are still unclear.Based o...Dolichospermum spp.and Microcystis spp.are two common cyanobacteria that form blooms in the Changjiang(Yangtze)River basin,but the environmental conditions for their succession in large lakes are still unclear.Based on daily monitoring data from Meiliang Bay in Taihu Lake from March to June,2016-2018,we studied the environmental conditions necessary for the succession of these two cyanobacteria.Results show that from March to June,the dominant genera of cyanobacteria experienced succession and co-dominated with Microcystis.The succession process included three stages.In StageⅠ,the biomass of Dolichospermum and Microcystis was similar(March),but Dolichospermum was dominant for most of the period.In StageⅡ,dominance alternated between Dolichospermum and Microcystis(April to mid-May).In StageⅢ,the biomass of Microcystis dominated(mid-May to June).In addition,temperature and nutrients across the three stages varied significantly.The average temperature increased continuously from 10.9 to 18.4,and to 24.2℃.The total nitrogen content decreased from 2.87 to 2.40,and to 1.86 mg/L.The total phosphorus content increased from 0.08 to 0.09,and to 0.12 mg/L.Correlation analysis revealed that Microcystis biomass was positively correlated with temperature and total phosphorus.Dolichospermum biomass was positively correlated with total nitrogen.Classification and regression tree displays that when the temperature was below 18.1℃,Dolichospermum dominated;above 18.1℃,Microcystis took over.Further analysis revealed that when temperature reached 18℃,the biomass of Microcystis increased exponentially,and the biomass of Dolichospermum exhibited a Gaussian distribution trend.This finding indicated that temperature was the key factor in the succession of Dolichospermum and Microcystis in nutrient-rich shallow lakes.As nitrogen and phosphorus concentrations decrease,the dominant species of cyanobacteria will diversify its development.The results of this study provide a foundation for risk prediction and control strategies for cyanobacterial blooms in lakes and reservoirs.展开更多
Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery...Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery after spinal cord injury remains unclear.In the present study,we established a rat model of spinal cord injury based on impact injury from a dropped weight and then intraperitoneally injected the rats with conditioned medium from human dental pulp stem cells.We found that the conditioned medium effectively promoted the recovery of sensory and motor functions in rats with spinal cord injury,decreased expression of the microglial pyroptosis markers NLRP3,GSDMD,caspase-1,and interleukin-1β,promoted axonal and myelin regeneration,and inhibited the formation of glial scars.In addition,in a lipopolysaccharide-induced BV2 microglia model,conditioned medium from human dental pulp stem cells protected cells from pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway.These results indicate that conditioned medium from human dental pulp stem cells can reduce microglial pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway,thereby promoting the recovery of neurological function after spinal cord injury.Therefore,conditioned medium from human dental pulp stem cells may become an alternative therapy for spinal cord injury.展开更多
We study the initial-boundary value problem of the Navier-Stokes equations for incompressible fluids in a general domain in R^n with compact and smooth boundary, subject to the kinematic and vorticity boundary conditi...We study the initial-boundary value problem of the Navier-Stokes equations for incompressible fluids in a general domain in R^n with compact and smooth boundary, subject to the kinematic and vorticity boundary conditions on the non-flat boundary. We observe that, under the nonhomogeneous boundary conditions, the pressure p can be still recovered by solving the Neumann problem for the Poisson equation. Then we establish the well-posedness of the unsteady Stokes equations and employ the solution to reduce our initial-boundary value problem into an initial-boundary value problem with absolute boundary conditions. Based on this, we first establish the well-posedness for an appropriate local linearized problem with the absolute boundary conditions and the initial condition (without the incompressibility condition), which establishes a velocity mapping. Then we develop apriori estimates for the velocity mapping, especially involving the Sobolev norm for the time-derivative of the mapping to deal with the complicated boundary conditions, which leads to the existence of the fixed point of the mapping and the existence of solutions to our initial-boundary value problem. Finally, we establish that, when the viscosity coefficient tends zero, the strong solutions of the initial-boundary value problem in R^n(n ≥ 3) with nonhomogeneous vorticity boundary condition converge in L^2 to the corresponding Euler equations satisfying the kinematic condition.展开更多
In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken a...In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken as the model inputs,which brings uncertainties to LSP results.This study aims to reveal the influence rules of the different proportional random errors in conditioning factors on the LSP un-certainties,and further explore a method which can effectively reduce the random errors in conditioning factors.The original conditioning factors are firstly used to construct original factors-based LSP models,and then different random errors of 5%,10%,15% and 20%are added to these original factors for con-structing relevant errors-based LSP models.Secondly,low-pass filter-based LSP models are constructed by eliminating the random errors using low-pass filter method.Thirdly,the Ruijin County of China with 370 landslides and 16 conditioning factors are used as study case.Three typical machine learning models,i.e.multilayer perceptron(MLP),support vector machine(SVM)and random forest(RF),are selected as LSP models.Finally,the LSP uncertainties are discussed and results show that:(1)The low-pass filter can effectively reduce the random errors in conditioning factors to decrease the LSP uncertainties.(2)With the proportions of random errors increasing from 5%to 20%,the LSP uncertainty increases continuously.(3)The original factors-based models are feasible for LSP in the absence of more accurate conditioning factors.(4)The influence degrees of two uncertainty issues,machine learning models and different proportions of random errors,on the LSP modeling are large and basically the same.(5)The Shapley values effectively explain the internal mechanism of machine learning model predicting landslide sus-ceptibility.In conclusion,greater proportion of random errors in conditioning factors results in higher LSP uncertainty,and low-pass filter can effectively reduce these random errors.展开更多
Copula functions have been widely used in stochastic simulation and prediction of streamflow.However,existing models are usually limited to single two-dimensional or three-dimensional copulas with the same bivariate b...Copula functions have been widely used in stochastic simulation and prediction of streamflow.However,existing models are usually limited to single two-dimensional or three-dimensional copulas with the same bivariate block for all months.To address this limitation,this study developed a mixed D-vine copula-based conditional quantile model that can capture temporal correlations.This model can generate streamflow by selecting different historical streamflow variables as the conditions for different months and by exploiting the conditional quantile functions of streamflows in different months with mixed D-vine copulas.The up-to-down sequential method,which couples the maximum weight approach with the Akaike information criteria and the maximum likelihood approach,was used to determine the structures of multivariate Dvine copulas.The developed model was used in a case study to synthesize the monthly streamflow at the Tangnaihai hydrological station,the inflow control station of the Longyangxia Reservoir in the Yellow River Basin.The results showed that the developed model outperformed the commonly used bivariate copula model in terms of the performance in simulating the seasonality and interannual variability of streamflow.This model provides useful information for water-related natural hazard risk assessment and integrated water resources management and utilization.展开更多
The Guanpo pegmatite field in the North Qinling orogenic belt(NQB),China,hosts the most abundant LCT pegmatites.However,their emplacement conditions and structural control remain unexplored.In this contribution,we inv...The Guanpo pegmatite field in the North Qinling orogenic belt(NQB),China,hosts the most abundant LCT pegmatites.However,their emplacement conditions and structural control remain unexplored.In this contribution,we investigated it combining pegmatite orientation measurement with oxygen isotope geothermometry and fluid inclusion study.The orientations of type A1 pegmatites(P_(f)<σ_(2))are predominantly influenced by P-and T-fractures due to simple shearing in Shiziping dextral thrust shear zone during D_(2)deformation,whereas type A2 pegmatites(contemporaneous with D_(4))are governed by hydraulic fractures aligned with S_(0)and S_(0+1)stemming from fluid pressure(P_(f)<σ_(2)).Additionally,type B pegmatites(P_(f)≤σ_(2))exhibit orientations shaped by en echelon extensional fractures in local ductile shear zones(contemporaneous with D_(3)).The albite-quartz oxygen isotope geothermometry and microthermometric analysis of fluid inclusions in elbaites from the latest pegmatites(including types B and A2)suggest that the crystallization P-T for late magmatic and hydrothermal stages are 527.5-559.2℃,320℃,3.1-3.6 kbar and 2.0 kbar,respectively.Our observations along with previous studies suggest that the genesis of the LCT pegmatites was a long-term,multi-stage event during early Paleozoic orogeny(including the collision stage)of the NQB,and was facilitated by various local fractures.展开更多
Crystallineγ-Ga_(2)O_(3)@rGO core-shell nanostructures are synthesized in gram scale,which are accomplished by a facile sonochemical strategy under ambient condition.They are composed of uniformγ-Ga_(2)O_(3)nanosphe...Crystallineγ-Ga_(2)O_(3)@rGO core-shell nanostructures are synthesized in gram scale,which are accomplished by a facile sonochemical strategy under ambient condition.They are composed of uniformγ-Ga_(2)O_(3)nanospheres encapsulated by reduced graphene oxide(rGO)nanolayers,and their formation is mainly attributed to the existed opposite zeta potential between the Ga_(2)O_(3)and rGO.The as-constructed lithium-ion batteries(LIBs)based on as-fabricatedγ-Ga_(2)O_(3)@rGO nanostructures deliver an initial discharge capacity of 1000 mAh g^(-1)at 100 mA g^(-1)and reversible capacity of 600 mAh g^(-1)under 500 mA g^(-1)after 1000 cycles,respectively,which are remarkably higher than those of pristineγ-Ga_(2)O_(3)with a much reduced lifetime of 100 cycles and much lower capacity.Ex situ XRD and XPS analyses demonstrate that the reversible LIBs storage is dominant by a conversion reaction and alloying mechanism,where the discharged product of liquid metal Ga exhibits self-healing ability,thus preventing the destroy of electrodes.Additionally,the rGO shell could act robustly as conductive network of the electrode for significantly improved conductivity,endowing the efficient Li storage behaviors.This work might provide some insight on mass production of advanced electrode materials under mild condition for energy storage and conversion applications.展开更多
In this article, we consider the structured condition numbers for LDU, factorization by using the modified matrix-vector approach and the differential calculus, which can be represented by sets of parameters. By setti...In this article, we consider the structured condition numbers for LDU, factorization by using the modified matrix-vector approach and the differential calculus, which can be represented by sets of parameters. By setting the specific norms and weight parameters, we present the expressions of the structured normwise, mixed, componentwise condition numbers and the corresponding results for unstructured ones. In addition, we investigate the statistical estimation of condition numbers of LDU factorization using the probabilistic spectral norm estimator and the small-sample statistical condition estimation method, and devise three algorithms. Finally, we compare the structured condition numbers with the corresponding unstructured ones in numerical experiments.展开更多
Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,nega...Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been recorded.Multiple conditioning regimens were extracted from various literature searches from databases like PubMed,Google scholar,EMBASE,and Cochrane.Conditioning regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning regimen.In multiple myeloma,the most effective regimen was high dose melphalan(MEL)given at a dose of 200/mg/m2.The comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+MEL regarding OS and BU+VP16 regarding LFS.In case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of recurrence.However,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and LFS.With respect to Hodgkin’s lymphoma,mitoxantrone(MITO)/MEL overtook carmustine,VP16,cytarabine,and MEL in view of PFS and vice versa regarding OS.Non-Hodgkin’s lymphoma patients were administered MITO(60 mg/m2)and MEL(180 mg/m2)which showed promising results.Lastly,amyloidosis was considered,and the regimen that proved to be competent was MEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases.展开更多
基金Supported by Scientific Research Program of Guangxi Provincial Department of Education(201010LX014)~~
文摘It was proposed that park planning should be based on local economic development,should focus on the preservation of primitive ecological conditions and the application of low-carbon and energy-saving concepts.The planning of Ancient Banyan Park in Mengshan County by following the principles of respecting local history and culture,improving functions and supporting facilities,human-centered,overall planning and all-around consideration,respecting characteristics of the local area(the planning site),satisfying operation requirements of the park,applying low-carbon and energy-saving concepts,and avoiding over-engineering,aimed at protecting natural images of the park,primitive history,culture and characteristics of the local area and providing a space for local residents' various activities.Modern aesthetic forms were combined,cultural connotation of natural environment stressed to build a landscape space system of the Ancient Banyan Park that matches well with environment of the planning site.The park was designed into 4 functional areas:sport area,fitness plaza area,garden recreational area and ancient banyan cultural area.Different functions of these subareas were taken into consideration to create conservation-minded garden landscapes which were both independent and unified.
文摘With the continuous development of gold ore prospecting and exploration in recent years a new type of micro-disseminated gold deposits have been found in the regions of Southwest Guizhou Province and Northwest Guangxi Zhuang Autonomous Region,with the orebodies directly occurring in diabase or in the contact zone between diabase and strata.The orebodies are strictly controlled by fault structures.The discovery of this type of gold deposits has brought about new prospects for gold ore prospecting in the Yunnan-Guizhou-Guangxi Golden Triangle region.From the preliminary analysis of the geological characteristics of the Qiaoxiang gold deposit in Wangmo County,in combination with the results of research work in the adjacent areas in recent years,this paper roughly described the geological characteristics and metallogenic conditions of this type of gold ore deposits with an attempt to make more and more geologists pay enough attention to this type of gold ore deposits,so as to promote gold ore prospecting in Guizhou Province to develop toward a variety of types of gold deposits in all round way.
基金support by the National Natural Science Foundation of China(Grant No.52402520)。
文摘Actuator faults can be critical in turbofan engines as they can lead to stall,surge,loss of thrust and failure of speed control.Thus,fault diagnosis of gas turbine actuators has attracted considerable attention,from both academia and industry.However,the extensive literature that exists on this topic does not address identifying the severity of actuator faults and focuses mainly on actuator fault detection and isolation.In addition,previous studies of actuator fault identification have not dealt with multiple concurrent faults in real time,especially when these are accompanied by sudden failures under dynamic conditions.This study develops component-level models for fault identification in four typical actuators used in high-bypass ratio turbofan engines under both dynamic and steady-state conditions and these are then integrated with the engine performance model developed by the authors.The research results reported here present a novel method of quantifying actuator faults using dynamic effect compensation.The maximum error for each actuator is less than0.06%and 0.07%,with average computational time of less than 0.0058 s and 0.0086 s for steady-state and transient cases,respectively.These results confirm that the proposed method can accurately and efficiently identify concurrent actuator fault for an engine operating under either transient or steady-state conditions,even in the case of a sudden malfunction.The research results emonstrate the potential benefit to emergency response capabilities by introducing this method of monitoring the health of aero engines.
基金supported partly by the National Natural Science Foundation of China,No.82071332the Chongqing Natural Science Foundation Joint Fund for Innovation and Development,No.CSTB2023NSCQ-LZX0041 (both to ZG)。
文摘Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.
基金supported by the Natural Science Foundation of Xinjiang Uygur Autonomous Region(Grant No.2022D01B 187)。
文摘Federated learning(FL)is a distributed machine learning paradigm for edge cloud computing.FL can facilitate data-driven decision-making in tactical scenarios,effectively addressing both data volume and infrastructure challenges in edge environments.However,the diversity of clients in edge cloud computing presents significant challenges for FL.Personalized federated learning(pFL)received considerable attention in recent years.One example of pFL involves exploiting the global and local information in the local model.Current pFL algorithms experience limitations such as slow convergence speed,catastrophic forgetting,and poor performance in complex tasks,which still have significant shortcomings compared to the centralized learning.To achieve high pFL performance,we propose FedCLCC:Federated Contrastive Learning and Conditional Computing.The core of FedCLCC is the use of contrastive learning and conditional computing.Contrastive learning determines the feature representation similarity to adjust the local model.Conditional computing separates the global and local information and feeds it to their corresponding heads for global and local handling.Our comprehensive experiments demonstrate that FedCLCC outperforms other state-of-the-art FL algorithms.
基金supported by the National Natural Science Foundation of China(Nos.12371255 and 11975306)the Natural Science Foundation of Jiangsu Province(No.BK20181351)+3 种基金the Six Talent Peaks Project in Jiangsu Province(No.JY-059)the 333 Project in Jiangsu Provincethe Fundamental Research Fund for the Central Universities(Nos.2019ZDPY07)the Graduate Innovation Program of China University of Mining and Technology(No.2022WLJCRCZL139).
文摘The focusing modified Korteweg-de Vries(mKdV)equation with multiple high-order poles under the nonzero boundary conditions is first investigated via developing a Riemann-Hilbert(RH)approach.We begin with the asymptotic property,symmetry and analyticity of the Jost solutions,and successfully construct the RH problem of the focusing mKdV equation.We solve the RH problem when 1/S_(11)(k)has a single highorder pole and multiple high-order poles.Furthermore,we derive the soliton solutions of the focusing mKdV equation which corresponding with a single high-order pole and multiple high-order poles,respectively.Finally,the dynamics of one-and two-soliton solutions are graphically discussed.
基金National Key R&D Program of China(Grant No.2023YFE0114600)The National Natural Science Foundation of China(NSFC)-(Grant No.52477029)+1 种基金Joint Laboratory of China-Morocco Green Energy and Advanced Materials,The Youth Innovation Team of Shaanxi Universities,The Xi’an City Science and Technology Project(No.23GXFW0070)Xi’an International Science and Technology Cooperation Base.
文摘To realize carbon neutrality,there is an urgent need to develop sustainable,green energy systems(especially solar energy systems)owing to the environmental friendliness of solar energy,given the substantial greenhouse gas emissions from fossil fuel-based power sources.When it comes to the evolution of intelligent green energy systems,Internet of Things(IoT)-based green-smart photovoltaic(PV)systems have been brought into the spotlight owing to their cutting-edge sensing and data-processing technologies.This review is focused on three critical segments of IoT-based green-smart PV systems.First,the climatic parameters and sensing technologies for IoT-based PV systems under extreme weather conditions are presented.Second,the methods for processing data from smart sensors are discussed,in order to realize health monitoring of PV systems under extreme environmental conditions.Third,the smart materials applied to sensors and the insulation materials used in PV backsheets are susceptible to aging,and these materials and their aging phenomena are highlighted in this review.This review also offers new perspectives for optimizing the current international standards for green energy systems using big data from IoT-based smart sensors.
基金the National Natural Science Foundation of China(grant no.51208419).
文摘Automated pavement condition survey is of critical importance to road network management.There are three primary tasks involved in pavement condition surveys,namely data collection,data processing and condition evaluation.Artificial intelligence(AI)has achieved many breakthroughs in almost every aspect of modern technology over the past decade,and undoubtedly offers a more robust approach to automated pavement condition survey.This article aims to provide a comprehensive review on data collection systems,data processing algorithms and condition evaluation methods proposed between 2010 and 2023 for intelligent pavement condition survey.In particular,the data collection system includes AI-driven hardware devices and automated pavement data collection vehicles.The AI-driven hardware devices including right-of-way(ROW)cameras,ground penetrating radar(GPR)devices,light detection and ranging(LiDAR)devices,and advanced laser imaging systems,etc.These different hardware components can be selectively mounted on a vehicle to simultaneously collect multimedia information about the pavement.In addition,this article pays close attention to the application of artificial intelligence methods in detecting pavement distresses,measuring pavement roughness,identifying pavement rutting,analyzing skid resistance and evaluating structural strength of pavements.Based upon the analysis of a variety of the state-of-the-art artificial intelligence methodologies,remaining challenges and future needs with respect to intelligent pavement condition survey are discussed eventually.
文摘Laminated composites are widely used in many engineering industries such as aircraft, spacecraft, boat hulls, racing car bodies, and storage tanks. We analyze the 3D deformations of a multilayered, linear elastic, anisotropic rectangular plate subjected to arbitrary boundary conditions on one edge and simply supported on other edge. The rectangular laminate consists of anisotropic and homogeneous laminae of arbitrary thicknesses. This study presents the elastic analysis of laminated composite plates subjected to sinusoidal mechanical loading under arbitrary boundary conditions. Least square finite element solutions for displacements and stresses are investigated using a mathematical model, called a state-space model, which allows us to simultaneously solve for these field variables in the composite structure’s domain and ensure that continuity conditions are satisfied at layer interfaces. The governing equations are derived from this model using a numerical technique called the least-squares finite element method (LSFEM). These LSFEMs seek to minimize the squares of the governing equations and the associated side conditions residuals over the computational domain. The model is comprised of layerwise variables such as displacements, out-of-plane stresses, and in- plane strains, treated as independent variables. Numerical results are presented to demonstrate the response of the laminated composite plates under various arbitrary boundary conditions using LSFEM and compared with the 3D elasticity solution available in the literature.
基金the financial support from the National Natural Science Foundation of China(Grant no.42077263).
文摘Microseismic event location is one of the core parameters in microseismic monitoring,and the accuracy of localization will directly affect the effectiveness of engineering applications.However,limited by spatial factors,the geometry of the sensor installation will be close to linear,which makes the localization equation suffer from the pathological problem,and the localization accuracy is greatly reduced.To address this problem,the reasons for the pathological problem are analyzed from the perspective of the objective function residuals and coefficient matrix.The pathological problem is caused by the combined effect of the poorer sensor array and data errors,and its residual isosurface shows a conical distribution,and as the residual value decreases,the apex of the isosurface gradually extends to the far side,and the localization results do not converge.For this reason,an improved regularized Newton downhill localization algorithm is proposed.In this method,firstly,the Newtonian downhill method is improved so that the magnitudes of the seismic source parameters are the same,and the condition number of the coefficient matrix is reduced;then,the L-curve method is used to calculate the regularization factor for the pathological equations,and the coefficient matrix is improved;finally,the pathological equations are regularized,and the seismic source coordinates are obtained by the improved Newtonian downhill method.The results of engineering applications show that compared with the traditional algorithm based on automatic of P-arrival picking,the number of effective microseismic events calculated by the proposed localization algorithm is increased by 194.7%,and the localization accuracy is substantially improved.The proposed algorithm reduces the problem of low accuracy of S-arrival picking and allows localization using only P-wave arrival.The method reduces the quality requirements of the data and significantly improves the utilization of microseismic events and positioning accuracy.
基金Supported by the National Natural Science Foundation of China(No.42007159)the Network Security and Informatization Project of Chinese Academy of Sciences(No.CAS-WX2021SF-050402)+2 种基金the Water Science and Technology Project of Jiangsu Province(No.2020004)the Key Project of Nanjing Institute of Geography and LimnologyChinese Academy of Sciences(No.NIGLAS2022GS03)。
文摘Dolichospermum spp.and Microcystis spp.are two common cyanobacteria that form blooms in the Changjiang(Yangtze)River basin,but the environmental conditions for their succession in large lakes are still unclear.Based on daily monitoring data from Meiliang Bay in Taihu Lake from March to June,2016-2018,we studied the environmental conditions necessary for the succession of these two cyanobacteria.Results show that from March to June,the dominant genera of cyanobacteria experienced succession and co-dominated with Microcystis.The succession process included three stages.In StageⅠ,the biomass of Dolichospermum and Microcystis was similar(March),but Dolichospermum was dominant for most of the period.In StageⅡ,dominance alternated between Dolichospermum and Microcystis(April to mid-May).In StageⅢ,the biomass of Microcystis dominated(mid-May to June).In addition,temperature and nutrients across the three stages varied significantly.The average temperature increased continuously from 10.9 to 18.4,and to 24.2℃.The total nitrogen content decreased from 2.87 to 2.40,and to 1.86 mg/L.The total phosphorus content increased from 0.08 to 0.09,and to 0.12 mg/L.Correlation analysis revealed that Microcystis biomass was positively correlated with temperature and total phosphorus.Dolichospermum biomass was positively correlated with total nitrogen.Classification and regression tree displays that when the temperature was below 18.1℃,Dolichospermum dominated;above 18.1℃,Microcystis took over.Further analysis revealed that when temperature reached 18℃,the biomass of Microcystis increased exponentially,and the biomass of Dolichospermum exhibited a Gaussian distribution trend.This finding indicated that temperature was the key factor in the succession of Dolichospermum and Microcystis in nutrient-rich shallow lakes.As nitrogen and phosphorus concentrations decrease,the dominant species of cyanobacteria will diversify its development.The results of this study provide a foundation for risk prediction and control strategies for cyanobacterial blooms in lakes and reservoirs.
基金supported by the Research Foundation of Technology Committee of Tongzhou District,No.KJ2019CX001(to SX).
文摘Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery after spinal cord injury remains unclear.In the present study,we established a rat model of spinal cord injury based on impact injury from a dropped weight and then intraperitoneally injected the rats with conditioned medium from human dental pulp stem cells.We found that the conditioned medium effectively promoted the recovery of sensory and motor functions in rats with spinal cord injury,decreased expression of the microglial pyroptosis markers NLRP3,GSDMD,caspase-1,and interleukin-1β,promoted axonal and myelin regeneration,and inhibited the formation of glial scars.In addition,in a lipopolysaccharide-induced BV2 microglia model,conditioned medium from human dental pulp stem cells protected cells from pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway.These results indicate that conditioned medium from human dental pulp stem cells can reduce microglial pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway,thereby promoting the recovery of neurological function after spinal cord injury.Therefore,conditioned medium from human dental pulp stem cells may become an alternative therapy for spinal cord injury.
基金supported in part by the National Science Foundation under Grants DMS-0807551, DMS-0720925, and DMS-0505473the Natural Science Foundationof China (10728101)supported in part by EPSRC grant EP/F029578/1
文摘We study the initial-boundary value problem of the Navier-Stokes equations for incompressible fluids in a general domain in R^n with compact and smooth boundary, subject to the kinematic and vorticity boundary conditions on the non-flat boundary. We observe that, under the nonhomogeneous boundary conditions, the pressure p can be still recovered by solving the Neumann problem for the Poisson equation. Then we establish the well-posedness of the unsteady Stokes equations and employ the solution to reduce our initial-boundary value problem into an initial-boundary value problem with absolute boundary conditions. Based on this, we first establish the well-posedness for an appropriate local linearized problem with the absolute boundary conditions and the initial condition (without the incompressibility condition), which establishes a velocity mapping. Then we develop apriori estimates for the velocity mapping, especially involving the Sobolev norm for the time-derivative of the mapping to deal with the complicated boundary conditions, which leads to the existence of the fixed point of the mapping and the existence of solutions to our initial-boundary value problem. Finally, we establish that, when the viscosity coefficient tends zero, the strong solutions of the initial-boundary value problem in R^n(n ≥ 3) with nonhomogeneous vorticity boundary condition converge in L^2 to the corresponding Euler equations satisfying the kinematic condition.
基金This work is funded by the National Natural Science Foundation of China(Grant Nos.42377164 and 52079062)the National Science Fund for Distinguished Young Scholars of China(Grant No.52222905).
文摘In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken as the model inputs,which brings uncertainties to LSP results.This study aims to reveal the influence rules of the different proportional random errors in conditioning factors on the LSP un-certainties,and further explore a method which can effectively reduce the random errors in conditioning factors.The original conditioning factors are firstly used to construct original factors-based LSP models,and then different random errors of 5%,10%,15% and 20%are added to these original factors for con-structing relevant errors-based LSP models.Secondly,low-pass filter-based LSP models are constructed by eliminating the random errors using low-pass filter method.Thirdly,the Ruijin County of China with 370 landslides and 16 conditioning factors are used as study case.Three typical machine learning models,i.e.multilayer perceptron(MLP),support vector machine(SVM)and random forest(RF),are selected as LSP models.Finally,the LSP uncertainties are discussed and results show that:(1)The low-pass filter can effectively reduce the random errors in conditioning factors to decrease the LSP uncertainties.(2)With the proportions of random errors increasing from 5%to 20%,the LSP uncertainty increases continuously.(3)The original factors-based models are feasible for LSP in the absence of more accurate conditioning factors.(4)The influence degrees of two uncertainty issues,machine learning models and different proportions of random errors,on the LSP modeling are large and basically the same.(5)The Shapley values effectively explain the internal mechanism of machine learning model predicting landslide sus-ceptibility.In conclusion,greater proportion of random errors in conditioning factors results in higher LSP uncertainty,and low-pass filter can effectively reduce these random errors.
基金supported by the National Natural Science Foundation of China(Grant No.52109010)the Postdoctoral Science Foundation of China(Grant No.2021M701047)the China National Postdoctoral Program for Innovative Talents(Grant No.BX20200113).
文摘Copula functions have been widely used in stochastic simulation and prediction of streamflow.However,existing models are usually limited to single two-dimensional or three-dimensional copulas with the same bivariate block for all months.To address this limitation,this study developed a mixed D-vine copula-based conditional quantile model that can capture temporal correlations.This model can generate streamflow by selecting different historical streamflow variables as the conditions for different months and by exploiting the conditional quantile functions of streamflows in different months with mixed D-vine copulas.The up-to-down sequential method,which couples the maximum weight approach with the Akaike information criteria and the maximum likelihood approach,was used to determine the structures of multivariate Dvine copulas.The developed model was used in a case study to synthesize the monthly streamflow at the Tangnaihai hydrological station,the inflow control station of the Longyangxia Reservoir in the Yellow River Basin.The results showed that the developed model outperformed the commonly used bivariate copula model in terms of the performance in simulating the seasonality and interannual variability of streamflow.This model provides useful information for water-related natural hazard risk assessment and integrated water resources management and utilization.
基金supported by the National Key R&D Program of China(Grant Nos.2021YFC2901902 and 2019YFC0605202)。
文摘The Guanpo pegmatite field in the North Qinling orogenic belt(NQB),China,hosts the most abundant LCT pegmatites.However,their emplacement conditions and structural control remain unexplored.In this contribution,we investigated it combining pegmatite orientation measurement with oxygen isotope geothermometry and fluid inclusion study.The orientations of type A1 pegmatites(P_(f)<σ_(2))are predominantly influenced by P-and T-fractures due to simple shearing in Shiziping dextral thrust shear zone during D_(2)deformation,whereas type A2 pegmatites(contemporaneous with D_(4))are governed by hydraulic fractures aligned with S_(0)and S_(0+1)stemming from fluid pressure(P_(f)<σ_(2)).Additionally,type B pegmatites(P_(f)≤σ_(2))exhibit orientations shaped by en echelon extensional fractures in local ductile shear zones(contemporaneous with D_(3)).The albite-quartz oxygen isotope geothermometry and microthermometric analysis of fluid inclusions in elbaites from the latest pegmatites(including types B and A2)suggest that the crystallization P-T for late magmatic and hydrothermal stages are 527.5-559.2℃,320℃,3.1-3.6 kbar and 2.0 kbar,respectively.Our observations along with previous studies suggest that the genesis of the LCT pegmatites was a long-term,multi-stage event during early Paleozoic orogeny(including the collision stage)of the NQB,and was facilitated by various local fractures.
基金supported by National Natural Science Foundation of China(NSFC,Grant No.51972178)Natural Science Foundation of Ningbo(2022J139)Ningbo Yongjiang Talent Introduction Programme(2022A-227-G)
文摘Crystallineγ-Ga_(2)O_(3)@rGO core-shell nanostructures are synthesized in gram scale,which are accomplished by a facile sonochemical strategy under ambient condition.They are composed of uniformγ-Ga_(2)O_(3)nanospheres encapsulated by reduced graphene oxide(rGO)nanolayers,and their formation is mainly attributed to the existed opposite zeta potential between the Ga_(2)O_(3)and rGO.The as-constructed lithium-ion batteries(LIBs)based on as-fabricatedγ-Ga_(2)O_(3)@rGO nanostructures deliver an initial discharge capacity of 1000 mAh g^(-1)at 100 mA g^(-1)and reversible capacity of 600 mAh g^(-1)under 500 mA g^(-1)after 1000 cycles,respectively,which are remarkably higher than those of pristineγ-Ga_(2)O_(3)with a much reduced lifetime of 100 cycles and much lower capacity.Ex situ XRD and XPS analyses demonstrate that the reversible LIBs storage is dominant by a conversion reaction and alloying mechanism,where the discharged product of liquid metal Ga exhibits self-healing ability,thus preventing the destroy of electrodes.Additionally,the rGO shell could act robustly as conductive network of the electrode for significantly improved conductivity,endowing the efficient Li storage behaviors.This work might provide some insight on mass production of advanced electrode materials under mild condition for energy storage and conversion applications.
基金Supported by the National Natural Science Foundation of China(11671060).
文摘In this article, we consider the structured condition numbers for LDU, factorization by using the modified matrix-vector approach and the differential calculus, which can be represented by sets of parameters. By setting the specific norms and weight parameters, we present the expressions of the structured normwise, mixed, componentwise condition numbers and the corresponding results for unstructured ones. In addition, we investigate the statistical estimation of condition numbers of LDU factorization using the probabilistic spectral norm estimator and the small-sample statistical condition estimation method, and devise three algorithms. Finally, we compare the structured condition numbers with the corresponding unstructured ones in numerical experiments.
文摘Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been recorded.Multiple conditioning regimens were extracted from various literature searches from databases like PubMed,Google scholar,EMBASE,and Cochrane.Conditioning regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning regimen.In multiple myeloma,the most effective regimen was high dose melphalan(MEL)given at a dose of 200/mg/m2.The comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+MEL regarding OS and BU+VP16 regarding LFS.In case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of recurrence.However,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and LFS.With respect to Hodgkin’s lymphoma,mitoxantrone(MITO)/MEL overtook carmustine,VP16,cytarabine,and MEL in view of PFS and vice versa regarding OS.Non-Hodgkin’s lymphoma patients were administered MITO(60 mg/m2)and MEL(180 mg/m2)which showed promising results.Lastly,amyloidosis was considered,and the regimen that proved to be competent was MEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases.