Effect of Ear-Acupoint Pressing and Ear Apex(HX6,7)Bloodletting on Haemorheology in Chloasma Patients with Gan Depression Pattern

Objective： To explore the therapeutical effect of ear-acupoint pressing combined with Ear Apex （HX6,7） bloodletting on haemorheology in chloasma patients with Gan （Liver） depression pattern. Methods： A total of 180 chloasma patients were randomly assigned to three groups, 60 cases in each. Patients in the ear- acupuncture （EA） group were treated with ear-acupoint pressing combined with Ear Apex（HX6,7） bloodletting; vitamins C and E were put into practice in the Western medicine （WM） group together with 0.025% tretinoin cream for local external application; patients in the placebo group were treated with urea-cream by external use, while 30 healthy volunteers were in the control group. After a treatment course of 2 months, the changes of haemorheology, injury skin area, colour score and symptom score before and after the treatment were observed. Results： There was no significant difference on whole blood reduced viscosity （high shear, medium shear, and low shear）, erythrocyte aggregation index, hematocrit, plasma viscosity among the four groups （F=2.65, P〉0.05）. Compared with those before treatment, the whole blood viscosity （high shear） and whole blood reduced viscosity （high shear） after treatment in the EA group, the WM group and the placebo group were with no statistical significance （P〉0.05）. The injury skin area and colour score after treatment were significantly lower than those before treatment in the EA group and the WM group （P〈0.05）, while there was no significant difference in placebo group （P〉0.05）. Clinical symptoms of the EA group were obviously improved after the 2-month treatment, which was significantly different compared with those before treatment （P〈0.05）, there was significant difference compared with those of WM group and placebo group （P〈0.05）. Conclusion： There was no significant difference on haemorheology index between healthy people and chloasma patients without angionosis, cerebrovascular disease, hematopathy, metabolic disease or any other organic disease. Ear-acupoint pressing combined with Ear Apex （HX6,7） bloodletting can effectively improve concurrent symptoms, lighten chloasma and lower chloasma area in patients accompanied by Gan depression.

Effect of Yizhikang Powder on Hemorheological Indexes in Dairy Cattle with Retained Placenta

[ Objective ] The aim of the research was to reveal the mechanism of Yizhikang powder treatment on dairy cattle with retained placenta from the hemorheological perspective. [ Method] Dairy cattle with retained placenta were treated with oral administration of Yizhikang powder. And their hemorheological indexes were measured and compared with the corresponding indicators of pre-administration group, healthy group, and control group （sick but untreated）.[ Result] There was large decrease amplitude in the indexes （whole blood viscosity, plasma viscosity, whole blood viscosity reduction viscosity, ESR, ESR equation K value, fibrinogen content, platelet aggregation rate, RBC deformability IF value） of treated dairy cattle with retained placenta. By t test, the indexes, except hematocrit, decreased significantly after treatment （P〈0.05） and reached the status of post partum healthy cows. The hemorheological indexes didn＇t change significantly in the control group before and after treatment. [ Conclusion] Yizhikang powder could significantly improve blood flow state and reduced the occurrence of qi stagnation and blood stasis in perinatal period.

Type 2 diabetic patients with non-alcoholic fatty liver disease exhibit significant haemorheological abnormalities

Haemorheological abnormalities have been described in diabetes mellitus,as well as in non-alcoholic fatty liver disease(NAFLD).However,the relationship between the changes in liver fat content and haemorheology is unknown.The current study aims to show the correlation between haemorheological parameters and intrahepatic lipid content(IHLC)in patients with type 2 diabetes.The serum biochemical markers,such as fasting plasma glucose(FPG),haemoglobin A1c(HbA1c),liver enzymes,lipid profiles,and haemorheological properties,were examined.IHLC was quantified using proton magnetic resonance spectroscopy(1 H-MRS)scanning of the liver.A significant correlation was observed between IHLC and whole blood viscosity at high,middle,and low shear rates.IHLC also positively correlated with haematocrit,the reduced whole blood viscosity at low and middle shear rates,and the erythrocyte aggregation index.Diabetic patients with NAFLD exhibited significant haemorheological abnormalities compared with patients without NAFLD.In summary,haemorheological disorders are linked to non-alcoholic fatty liver in type 2 diabetes.