Roux-en-Y gastric bypass surgery（RYGB） has been demonstrated to be successful for treating type-II diabetes2mellitus（T2DM） patients with a body mass index（BMI）,30 kg/m,but reports of RYGB for T2 DM patients with...Roux-en-Y gastric bypass surgery（RYGB） has been demonstrated to be successful for treating type-II diabetes2mellitus（T2DM） patients with a body mass index（BMI）,30 kg/m,but reports of RYGB for T2 DM patients with22 a BMI,28 kg/mare lacking.T2 DM patients with a BMI,28 kg/mwere prospectively recruited to participate in this study in four hospitals.The endpoint was T2 DM remission（defined by fasting blood glucose（FBG） level,110 mg/d L and hemoglobin（Hb）A1c level,6.0% at 12 months postoperatively）.Predictors of remission were investigated by univariate and multivariate analyses.Eighty-six patients were assessed.Eighty-five patients underwent RYGB,with one conversion to open surgery.We compared the values of various variables before and after2 surgery.The mean BMI decreased from 24.68±2.12 to 21.72±2.43 kg/m（P,0.001）.Fifty-eight（67.4%） patients were not treated by drugs or insulin after surgery,and 20 patients（23.3%） had complete remission of T2 DM at12 months after surgery with an acceptable number of complications.The mean Hb A1 c level in the remission group was significantly lower than that in the non-remission group.Patients with a higher weight,lower Hb A1 c level,higher C-peptide level,and higher FBG level were more likely to have T2 DM remission in multivariate2 analyses.In conclusion,RYGB was effective and safe for treating T2 DM patients with a BMI,28 kg/m.Complete remission can be predicted by cases having a higher weight,lower Hb A1 c level,higher C-peptide level,and higher FBG level.展开更多
目的探讨血糖和糖化血红蛋白检测在2型糖尿病诊断中的价值。方法对2015年1月—2016年1月在该院进行FPG、2 h PG、Hb A1c测定的135例2型糖尿病患者及110名健康者对比,分析检测结果。结果糖尿病组FPG(10.20±1.32)mmol/L、2 h PG(17.6...目的探讨血糖和糖化血红蛋白检测在2型糖尿病诊断中的价值。方法对2015年1月—2016年1月在该院进行FPG、2 h PG、Hb A1c测定的135例2型糖尿病患者及110名健康者对比,分析检测结果。结果糖尿病组FPG(10.20±1.32)mmol/L、2 h PG(17.65±3.07)mmol/L、Hb A1c(9.32±0.47)明显高于健康组(P<0.05);2 h PG、Hb A1c确诊率明显高于FPG(P<0.05)。结论血糖和Hb A1c是诊断2型糖尿病的重要指标,具有重要的临床价值。展开更多
文摘Roux-en-Y gastric bypass surgery（RYGB） has been demonstrated to be successful for treating type-II diabetes2mellitus（T2DM） patients with a body mass index（BMI）,30 kg/m,but reports of RYGB for T2 DM patients with22 a BMI,28 kg/mare lacking.T2 DM patients with a BMI,28 kg/mwere prospectively recruited to participate in this study in four hospitals.The endpoint was T2 DM remission（defined by fasting blood glucose（FBG） level,110 mg/d L and hemoglobin（Hb）A1c level,6.0% at 12 months postoperatively）.Predictors of remission were investigated by univariate and multivariate analyses.Eighty-six patients were assessed.Eighty-five patients underwent RYGB,with one conversion to open surgery.We compared the values of various variables before and after2 surgery.The mean BMI decreased from 24.68±2.12 to 21.72±2.43 kg/m（P,0.001）.Fifty-eight（67.4%） patients were not treated by drugs or insulin after surgery,and 20 patients（23.3%） had complete remission of T2 DM at12 months after surgery with an acceptable number of complications.The mean Hb A1 c level in the remission group was significantly lower than that in the non-remission group.Patients with a higher weight,lower Hb A1 c level,higher C-peptide level,and higher FBG level were more likely to have T2 DM remission in multivariate2 analyses.In conclusion,RYGB was effective and safe for treating T2 DM patients with a BMI,28 kg/m.Complete remission can be predicted by cases having a higher weight,lower Hb A1 c level,higher C-peptide level,and higher FBG level.
文摘目的探讨血糖和糖化血红蛋白检测在2型糖尿病诊断中的价值。方法对2015年1月—2016年1月在该院进行FPG、2 h PG、Hb A1c测定的135例2型糖尿病患者及110名健康者对比,分析检测结果。结果糖尿病组FPG(10.20±1.32)mmol/L、2 h PG(17.65±3.07)mmol/L、Hb A1c(9.32±0.47)明显高于健康组(P<0.05);2 h PG、Hb A1c确诊率明显高于FPG(P<0.05)。结论血糖和Hb A1c是诊断2型糖尿病的重要指标,具有重要的临床价值。
