期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
瘦素在海人酸诱导小鼠颞叶癫痫海马损伤中的作用 被引量:4
1
作者 冯杰 邓子辉 +4 位作者 张金英 薛辉 梁辰 李建华 颜光涛 《解放军医学院学报》 CAS 2015年第4期388-392,共5页
目的探讨瘦素(Leptin)与颞叶癫痫发生、发展过程的关系。方法外源Leptin注射C57BL/6J小鼠后,右侧海马微量注射200 ng海人酸(kainic acid,KA)诱导颞叶癫痫,记录小鼠癫痫评分,1周后观察小鼠海马病理变化,包括Western blot检测Bax的表达水... 目的探讨瘦素(Leptin)与颞叶癫痫发生、发展过程的关系。方法外源Leptin注射C57BL/6J小鼠后,右侧海马微量注射200 ng海人酸(kainic acid,KA)诱导颞叶癫痫,记录小鼠癫痫评分,1周后观察小鼠海马病理变化,包括Western blot检测Bax的表达水平,尼式染色(Nissl staining)观察海马Hilus区神经元丢失,免疫荧光检测Hilus区星形胶质细胞活化与增殖。结果在200 ng KA诱导的颞叶癫痫模型基础上,10 mg/kg外源Leptin预处理后,癫痫评分增加约52%,Bax表达水平升高约75%(P<0.05),海马Hilus区神经元丢失严重,星形胶质细胞过度活化。结论 Leptin增加了KA诱导的神经元凋亡,加重KA诱导的神经病理过程。 展开更多
关键词 瘦素 海人酸 颞叶癫痫 星形胶质细胞 神经元 海马hilus
下载PDF
Strategies of laparoscopic spleen-preserving splenic hilar lymph node dissection for advanced proximal gastric cancer 被引量:2
2
作者 Qi-Yue Chen Chang-Ming Huang +9 位作者 Chao-Hui Zheng Ping Li Jian-Wei Xie Jia-Bin Wang Jian-Xian Lin Jun Lu Long-Long Cao Mi Lin Ru-Hong Tu Zhi-Liang Hong 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2016年第6期402-406,共5页
For advanced proximal gastric cancer(GC),splenic hilar(No.10) lymph nodes(LN) are crucial links in lymphatic drainage.According to the 14^(th) edition of the Japanese GC treatment guidelines,a D2 lymphadenectomy is th... For advanced proximal gastric cancer(GC),splenic hilar(No.10) lymph nodes(LN) are crucial links in lymphatic drainage.According to the 14^(th) edition of the Japanese GC treatment guidelines,a D2 lymphadenectomy is the standard surgery for advanced GC,and No.10 LN should be dissected for advanced proximal GC.In recent years,the preservation of organ function and the use of minimally invasive technology are being accepted by an increasing number of clinicians.Laparoscopic spleenpreserving splenic hilar LN dissection has become more accepted and is gradually being used in operations.However,because of the complexity of splenic hilar anatomy,mastering the strategies for laparoscopic spleen-preserving splenic hilar LN dissection is critical for successfully completing the operation. 展开更多
关键词 Gastric neoplasm LAPAROSCOPIC SPLENIC hilus LYMPHADENECTOMY Strategy
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部