Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(G.vulgarix) Nees.Methods:G.vulgarix Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade a...Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(G.vulgarix) Nees.Methods:G.vulgarix Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers,sores,inflammation, dyspepsia,healing of wounds,etc.The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation(HRBC) method and in vivo method was estimated on the carrageenan induced paw oedima.Results:Both the methods showed significant anti-inflammatory property of the different extracts tested. Conclusions:The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.展开更多
Objective:To evaluate the anti-inflamattory activity of Thunnus alalunga by both in vitro and in vivo methods.Methods:Anti-inflammatory activity of the chloroform water extract of Thunnus alalunga was done by both in ...Objective:To evaluate the anti-inflamattory activity of Thunnus alalunga by both in vitro and in vivo methods.Methods:Anti-inflammatory activity of the chloroform water extract of Thunnus alalunga was done by both in vitro and in vivo methods.In vitro method was done by human red blood cells membrane stabilization method(HRBC).In vivo evaluation was estimated on Wister albino rats.Acute toxicity studies were done on the extract and no toxicity was reported.Results: The percentage protection exhibited by 300 mg/mL concentration was more when compared to the other ones.The 400 mg/mL concentration showed potent activity on comparison with the standard during in vivo evaluation.Conclusions:In both means of estimation the extract of Thunnus alalunga was found to possess significant anti-inflammatory activity.展开更多
文摘Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(G.vulgarix) Nees.Methods:G.vulgarix Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers,sores,inflammation, dyspepsia,healing of wounds,etc.The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation(HRBC) method and in vivo method was estimated on the carrageenan induced paw oedima.Results:Both the methods showed significant anti-inflammatory property of the different extracts tested. Conclusions:The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.
文摘Objective:To evaluate the anti-inflamattory activity of Thunnus alalunga by both in vitro and in vivo methods.Methods:Anti-inflammatory activity of the chloroform water extract of Thunnus alalunga was done by both in vitro and in vivo methods.In vitro method was done by human red blood cells membrane stabilization method(HRBC).In vivo evaluation was estimated on Wister albino rats.Acute toxicity studies were done on the extract and no toxicity was reported.Results: The percentage protection exhibited by 300 mg/mL concentration was more when compared to the other ones.The 400 mg/mL concentration showed potent activity on comparison with the standard during in vivo evaluation.Conclusions:In both means of estimation the extract of Thunnus alalunga was found to possess significant anti-inflammatory activity.
