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Synthesis of Hymecromone Derivatives Containing Chiral 1,1'-Bi-2-naphthyl Moiety for Dual-mode Molecular Switch
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作者 ZiXingSHAN ChunGuangXIAO 《Chinese Chemical Letters》 SCIE CAS CSCD 2004年第8期892-894,共3页
Some hymecromone derivatives containing chiral 1,1'-bi-2-naphthyl moiety were synthesized and their photodimerizations were investigated. It was found that fluorescence intensity and optical rotation of the new ch... Some hymecromone derivatives containing chiral 1,1'-bi-2-naphthyl moiety were synthesized and their photodimerizations were investigated. It was found that fluorescence intensity and optical rotation of the new chiral hymecromone derivatives could be regulated by light. This property has potential significance for developing a new type of dual-mode molecular switch. 展开更多
关键词 hymecromone chiral 1 1'-bi-2-naphthol PHOTODIMERIZATION molecular switch.
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Studies on the Inclusion Complex Reaction and Fluorescent Analytical Application of β- cyclodextrin with Hymecromone
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作者 LUO Zhao fu, SONG Wei, PAN Zu ting College of Chemistry and Environmental Science, Wuhan University, Wuhan 430072, China 《Wuhan University Journal of Natural Sciences》 CAS 1999年第4期473-476,共4页
The inclusion complex reaction condition and the mechanism of β cyclodextrin with hymecromone have been studied by fluorescent spectrum. The fluorescent intensity and the stability of the system can be qreatly i... The inclusion complex reaction condition and the mechanism of β cyclodextrin with hymecromone have been studied by fluorescent spectrum. The fluorescent intensity and the stability of the system can be qreatly increased in qiven condition, and the formation constant of the inclusion complex reaction has been determined too. The system can be applied to the determination of trace amounts of hymecromone, the maximum fluorescent intensity is obtained with excitation and emission wavelength at 362 nm and 452 nm, respectively. The linear range for hymecromone is 8.0×10 -9 mol·L -1 to 1.0×10 -5 mol·L -1 . The detection limit is 1.8×10 -9 mol·L -1 . A simple, rapid and highly sensitive fluorimetric method is proposed for the determination of hymecromone. The results obtained are in agreement with those given by an official method. 展开更多
关键词 Fluorescent spectra hymecromone β cyclodextrin inclusion complex
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Viral miRNA-mediated activation of hyaluronan production as a drug target against COVID-19 被引量:1
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作者 Shuai Yang Lu Chen +1 位作者 Ying Tong Wenqiang Yu 《Acta Pharmaceutica Sinica B》 SCIE CAS CSCD 2022年第7期3195-3197,共3页
The global coronavirus disease 2019(COVID-19)pandemic has caused more than 6.1 million deaths until March 24,2022,as reported by the World Health Organization(WHO).Recently,breakthrough infections have appeared in ind... The global coronavirus disease 2019(COVID-19)pandemic has caused more than 6.1 million deaths until March 24,2022,as reported by the World Health Organization(WHO).Recently,breakthrough infections have appeared in individuals fully vaccinated against SARS-Co V-2^(1),which could be attributed to the rapid mutation of the RNA virus2.Currently,following the Delta variant,the Omicron variant of SARS-Co V-2 is increasingly becoming the dominant epidemic strain in the world. 展开更多
关键词 COVID-19 Human Identical Sequences HYALURONAN hymecromone Antisense oligonucleotides
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