The paper presents the coupling of artificial intelligence-AI and Object-oriented methodology applied for the construction of the model-based decision support system MBDSS.The MBDSS is designed for support the strate...The paper presents the coupling of artificial intelligence-AI and Object-oriented methodology applied for the construction of the model-based decision support system MBDSS.The MBDSS is designed for support the strategic decision making lead to the achievemellt of optimal path towardsmarket economy from the central planning situation in China. To meet user's various requirements,a series of innovations in software development have been carried out, such as system formalization with OBFRAMEs in an object-oriented paradigm for problem solving automation and techniques of modules intelligent cooperation, hybrid system of reasoning, connectionist framework utilization,etc. Integration technology has been highly emphasized and discussed in this article and an outlook to future software engineering is given in the conclusion section.展开更多
Phase analysis of titanium in steel has been carried out on thirty samples with different Ticontent from 0. 036 %-0. 204% . The various heat treatments for the samples are to anneal at 1050-1200 ℃ for a while ,follo...Phase analysis of titanium in steel has been carried out on thirty samples with different Ticontent from 0. 036 %-0. 204% . The various heat treatments for the samples are to anneal at 1050-1200 ℃ for a while ,followed by cooling at a rate of 1 . 10, 20 ℃/s ,respectively.It is achieved to separate and determine fine particle TiC ,coarse particle Ti_2CS and TiN ex-tracted from steel by controlling the oxidation potential and acidity of solutions.The results of quantrtative analysis of the individual phase show that 0. 09 %- 0. 13 % Ti-contentis enough to eliminate free nitrogen and transform MnS into Yi_2CS in steel effectively. In the case of0. 06 %- 0. 10 % Ti-content combined with annealing at 1050℃. and quick cooling at 20 ℃/s ,a prop-er amount of fine particle TiC can be precipitated and the rate of TiC (fine )/TiC (total )is high ,which arebeneficial to increase strength and toughness of steel. More Ti-content or cooling slowly will preciprtatemore coarse particle TiC which decreaces toughness severely. The proposed methods for quantitativephase analysis of titanium in steel are given in detail.展开更多
Hovenia acerba Lindl.(HA)was formerly used as a treatment for alcohol overdosing.To explore the mechanism of hepatoprotective effect of HA,the chemical components of Hovenia acerba Lindl.peduncles extract(HAPE)and Hov...Hovenia acerba Lindl.(HA)was formerly used as a treatment for alcohol overdosing.To explore the mechanism of hepatoprotective effect of HA,the chemical components of Hovenia acerba Lindl.peduncles extract(HAPE)and Hovenia acerba Lindl.seeds extract(HASE)were compared by UPLC-QTOF-MS.Moreover,the alcohol damage model of human normal hepatocytes(LO2)and male Kunming mice were used to measure their effects on alcoholic liver damage.Results showed that HASE had 32 kinds of phenolic compounds,and the main components were caffeic acid,vitexin-2′′-O-glucoside,ferulic acid hexoside,quercetin and its glycosides;HAPE had 24 kinds of phenolic compounds,and the main components were caffeic acid,kaempferol and chrysophano.The phenolic content of HASE(151.73±12.66 mg gallic acid equivalent per gram of dry weight)(mg GAE/g DW)was higher than that of HAPE(17.89±1.59 mg GAE/g DW).HASE and HAPE could increase the LO2 cell viability in the alcohol damage models.Moreover,the levels of triacylglycerol(TG),total cholesterol(TC),alanine aminotransferase(ALT),and aspartate aminotransferase(AST)were decreased,the activities of superoxide dismutase(SOD)and catalase(CAT)were increased,and the concentration of malondialdehyde(MDA)was decreased in both HASE and HAPE treated cell and mice groups.Results also showed that the concentration of reduced glutathione(GSH)and the activity of glutathione peroxidase(GSH-Px)were increased in mice.HASE and HAPE raised the mRNA expressions of nuclear factor erythroid-2 related factor 2(Nrf2)and activated antioxidant-related genes:heme oxygenase-1(HO-1),NADPH quinone acceptor oxidoreductase 1(NQO1),and glutamate-cysteine ligase modifier subunit(GCLM),and enhanced the expression of Nrf2 and HO-1 proteins.HASE and HAPE could also increase antioxidant activity by enhancing Nrf2-mediated inducible expression of HO-1 to protect hepatocytes from injury.Furthermore,HASE showed better liver protective effect than HAPE.This study demonstrated the protective benefits of Hovenia acerba Lindl.peduncles and seeds extracts on alcoholic liver injury.展开更多
文摘The paper presents the coupling of artificial intelligence-AI and Object-oriented methodology applied for the construction of the model-based decision support system MBDSS.The MBDSS is designed for support the strategic decision making lead to the achievemellt of optimal path towardsmarket economy from the central planning situation in China. To meet user's various requirements,a series of innovations in software development have been carried out, such as system formalization with OBFRAMEs in an object-oriented paradigm for problem solving automation and techniques of modules intelligent cooperation, hybrid system of reasoning, connectionist framework utilization,etc. Integration technology has been highly emphasized and discussed in this article and an outlook to future software engineering is given in the conclusion section.
文摘Phase analysis of titanium in steel has been carried out on thirty samples with different Ticontent from 0. 036 %-0. 204% . The various heat treatments for the samples are to anneal at 1050-1200 ℃ for a while ,followed by cooling at a rate of 1 . 10, 20 ℃/s ,respectively.It is achieved to separate and determine fine particle TiC ,coarse particle Ti_2CS and TiN ex-tracted from steel by controlling the oxidation potential and acidity of solutions.The results of quantrtative analysis of the individual phase show that 0. 09 %- 0. 13 % Ti-contentis enough to eliminate free nitrogen and transform MnS into Yi_2CS in steel effectively. In the case of0. 06 %- 0. 10 % Ti-content combined with annealing at 1050℃. and quick cooling at 20 ℃/s ,a prop-er amount of fine particle TiC can be precipitated and the rate of TiC (fine )/TiC (total )is high ,which arebeneficial to increase strength and toughness of steel. More Ti-content or cooling slowly will preciprtatemore coarse particle TiC which decreaces toughness severely. The proposed methods for quantitativephase analysis of titanium in steel are given in detail.
基金funded by the National Natural Science Foundation of China(Grant No.27964012)Double Thousand Plan of Jiangxi(jxsq2019201077).
文摘Hovenia acerba Lindl.(HA)was formerly used as a treatment for alcohol overdosing.To explore the mechanism of hepatoprotective effect of HA,the chemical components of Hovenia acerba Lindl.peduncles extract(HAPE)and Hovenia acerba Lindl.seeds extract(HASE)were compared by UPLC-QTOF-MS.Moreover,the alcohol damage model of human normal hepatocytes(LO2)and male Kunming mice were used to measure their effects on alcoholic liver damage.Results showed that HASE had 32 kinds of phenolic compounds,and the main components were caffeic acid,vitexin-2′′-O-glucoside,ferulic acid hexoside,quercetin and its glycosides;HAPE had 24 kinds of phenolic compounds,and the main components were caffeic acid,kaempferol and chrysophano.The phenolic content of HASE(151.73±12.66 mg gallic acid equivalent per gram of dry weight)(mg GAE/g DW)was higher than that of HAPE(17.89±1.59 mg GAE/g DW).HASE and HAPE could increase the LO2 cell viability in the alcohol damage models.Moreover,the levels of triacylglycerol(TG),total cholesterol(TC),alanine aminotransferase(ALT),and aspartate aminotransferase(AST)were decreased,the activities of superoxide dismutase(SOD)and catalase(CAT)were increased,and the concentration of malondialdehyde(MDA)was decreased in both HASE and HAPE treated cell and mice groups.Results also showed that the concentration of reduced glutathione(GSH)and the activity of glutathione peroxidase(GSH-Px)were increased in mice.HASE and HAPE raised the mRNA expressions of nuclear factor erythroid-2 related factor 2(Nrf2)and activated antioxidant-related genes:heme oxygenase-1(HO-1),NADPH quinone acceptor oxidoreductase 1(NQO1),and glutamate-cysteine ligase modifier subunit(GCLM),and enhanced the expression of Nrf2 and HO-1 proteins.HASE and HAPE could also increase antioxidant activity by enhancing Nrf2-mediated inducible expression of HO-1 to protect hepatocytes from injury.Furthermore,HASE showed better liver protective effect than HAPE.This study demonstrated the protective benefits of Hovenia acerba Lindl.peduncles and seeds extracts on alcoholic liver injury.
