目的:探讨营养包(Ying Yang Bao,YYB)服用时长和频率与6~24月龄婴幼儿血红蛋白(Hemoglobin,Hb)水平和贫血率之间的阈值效应关系。方法:研究数据来自于早期儿童营养包干预长期营养健康作用评估项目。采用t检验和卡方检验比较连续变量和...目的:探讨营养包(Ying Yang Bao,YYB)服用时长和频率与6~24月龄婴幼儿血红蛋白(Hemoglobin,Hb)水平和贫血率之间的阈值效应关系。方法:研究数据来自于早期儿童营养包干预长期营养健康作用评估项目。采用t检验和卡方检验比较连续变量和分类变量的组间差异。采用限制性立方样条回归检验YYB服用时长和频率与儿童血红蛋白(Hb)水平和贫血率之间的非线性趋势,探索可能存在的阈值效应关系。结果:YYB服用时长与Hb水平和贫血率的非线性趋势检验P值分别为0.665和0.211,服用频率与Hb水平和贫血率的非线性趋势检验P值分别为0.110和0.157。YYB服用时长达到8.68个月时,Hb水平变化的斜率β=0,贫血发生风险的OR=1;YYB服用频率达5.6袋/周时,Hb水平变化的斜率β=0,服用频率达4.6袋/周时,贫血发生风险的OR=1。结论:YYB服用时长和频率与6~24月龄婴幼儿Hb水平和贫血率之间存在线性关联;改善Hb水平和贫血率的最低有效时长约为8.6个月,最低有效频率约为5~6袋/周。展开更多
目的分析影响择期手术患者贮存式自体血利用率的因素,探讨其在择期手术贮存式自体血采集中的指导意义。方法 2013年1-11月对本院106名贮存式自体输血(PABD)患者和97名未备自体血患者贮存式自体血的利用进行回顾性分析,分析术前Hb水平、...目的分析影响择期手术患者贮存式自体血利用率的因素,探讨其在择期手术贮存式自体血采集中的指导意义。方法 2013年1-11月对本院106名贮存式自体输血(PABD)患者和97名未备自体血患者贮存式自体血的利用进行回顾性分析,分析术前Hb水平、术中预计出血量、自体血回输率、异体血输注及人均输血量等,对PABD的利用效率进行分析讨论。结果 106名PABD患者中有101例(95.3%)自体血得以回输,其中77例患者(72.6%)术中仅输注自体血,26例(24.5%)因术中出血较多而又输注异体血;5例(4.7%)自体血未回输。当患者术前Hb水平>125 g/L时,术中实际出血量<800 m L时,PABD组总的输血率和输血量均大于对照组(P<0.05);出血量>800 m L时,2组患者总输血量没有差异,与术前Hb水平无关。结论患者术前Hb水平较高且术中出血量较少时,实施PABD增加了总的输血量和自体血的报废率,对异体血的节约作用有限。展开更多
Patients with chronic inflammatory bowel diseases (IBD) have long been considered at risk for viral hepatitis B. However, recent epidemiological studies have found similar prevalence, or even lower than in the general...Patients with chronic inflammatory bowel diseases (IBD) have long been considered at risk for viral hepatitis B. However, recent epidemiological studies have found similar prevalence, or even lower than in the general population. The objective of this work is to determine the prevalence of viral hepatitis B (HVB) during IBD, to determine the risk factors in the service of Hepato-gastroenterology of university hospital Hassan II-Fez, and of evaluate the impact on therapeutic management. PATIENTS AND METHODS: This is a retrospective study, spread over a period of 17 years and a half (January 2001-June 2017). All patients treated for IBD who are tested for Hbs Ag and anti Hbcwere included. The HVB DNA levels were tested in case of positivity of HbsAgor anti Hbc. Results: Over the study period, 755 patients were included. The average age of our patients was 35 years [14 - 87] with a sex-ratio H/F of 0.67. We had 391 cases (51.8%) of Crohn’s disease (CD) and 364 cases (48.2%) of ulcerative colitis (UC). Anti HBctest was positive in 1.98% of cases (N = 15). In these patients, HBsAg was positive in 1.19% of cases (N = 9). The prevalence of HVB was 2.55% in CD (N = 10) versus 1.37% in UC (N = 5). In our work, no history of surgery, digestive endoscopy or transfusion has been shown to be a risk factor for viral transmission. CONCLUSION: The prevalence of HVB in IBD is similar to that of the general population. The safety of blood transfusions and the improvement of asepsis probably explain these results. However, the risk of viral reactivation during HVB, sometimes fatal under immunosuppressive treatment, requires systematic screening.展开更多
文摘目的:探讨营养包(Ying Yang Bao,YYB)服用时长和频率与6~24月龄婴幼儿血红蛋白(Hemoglobin,Hb)水平和贫血率之间的阈值效应关系。方法:研究数据来自于早期儿童营养包干预长期营养健康作用评估项目。采用t检验和卡方检验比较连续变量和分类变量的组间差异。采用限制性立方样条回归检验YYB服用时长和频率与儿童血红蛋白(Hb)水平和贫血率之间的非线性趋势,探索可能存在的阈值效应关系。结果:YYB服用时长与Hb水平和贫血率的非线性趋势检验P值分别为0.665和0.211,服用频率与Hb水平和贫血率的非线性趋势检验P值分别为0.110和0.157。YYB服用时长达到8.68个月时,Hb水平变化的斜率β=0,贫血发生风险的OR=1;YYB服用频率达5.6袋/周时,Hb水平变化的斜率β=0,服用频率达4.6袋/周时,贫血发生风险的OR=1。结论:YYB服用时长和频率与6~24月龄婴幼儿Hb水平和贫血率之间存在线性关联;改善Hb水平和贫血率的最低有效时长约为8.6个月,最低有效频率约为5~6袋/周。
文摘目的分析影响择期手术患者贮存式自体血利用率的因素,探讨其在择期手术贮存式自体血采集中的指导意义。方法 2013年1-11月对本院106名贮存式自体输血(PABD)患者和97名未备自体血患者贮存式自体血的利用进行回顾性分析,分析术前Hb水平、术中预计出血量、自体血回输率、异体血输注及人均输血量等,对PABD的利用效率进行分析讨论。结果 106名PABD患者中有101例(95.3%)自体血得以回输,其中77例患者(72.6%)术中仅输注自体血,26例(24.5%)因术中出血较多而又输注异体血;5例(4.7%)自体血未回输。当患者术前Hb水平>125 g/L时,术中实际出血量<800 m L时,PABD组总的输血率和输血量均大于对照组(P<0.05);出血量>800 m L时,2组患者总输血量没有差异,与术前Hb水平无关。结论患者术前Hb水平较高且术中出血量较少时,实施PABD增加了总的输血量和自体血的报废率,对异体血的节约作用有限。
文摘Patients with chronic inflammatory bowel diseases (IBD) have long been considered at risk for viral hepatitis B. However, recent epidemiological studies have found similar prevalence, or even lower than in the general population. The objective of this work is to determine the prevalence of viral hepatitis B (HVB) during IBD, to determine the risk factors in the service of Hepato-gastroenterology of university hospital Hassan II-Fez, and of evaluate the impact on therapeutic management. PATIENTS AND METHODS: This is a retrospective study, spread over a period of 17 years and a half (January 2001-June 2017). All patients treated for IBD who are tested for Hbs Ag and anti Hbcwere included. The HVB DNA levels were tested in case of positivity of HbsAgor anti Hbc. Results: Over the study period, 755 patients were included. The average age of our patients was 35 years [14 - 87] with a sex-ratio H/F of 0.67. We had 391 cases (51.8%) of Crohn’s disease (CD) and 364 cases (48.2%) of ulcerative colitis (UC). Anti HBctest was positive in 1.98% of cases (N = 15). In these patients, HBsAg was positive in 1.19% of cases (N = 9). The prevalence of HVB was 2.55% in CD (N = 10) versus 1.37% in UC (N = 5). In our work, no history of surgery, digestive endoscopy or transfusion has been shown to be a risk factor for viral transmission. CONCLUSION: The prevalence of HVB in IBD is similar to that of the general population. The safety of blood transfusions and the improvement of asepsis probably explain these results. However, the risk of viral reactivation during HVB, sometimes fatal under immunosuppressive treatment, requires systematic screening.
