A serological survey conducted among 196 pregnant women resident in and around Maiduguri, an urban town in north eastern Nigeria showed that 33 (16.8%) were asymptomatic carriers of hepatitis B virus surface antigen (...A serological survey conducted among 196 pregnant women resident in and around Maiduguri, an urban town in north eastern Nigeria showed that 33 (16.8%) were asymptomatic carriers of hepatitis B virus surface antigen (HBsAg). They are within the age range of 14-40 years with mean (± SD) age of 24.7 (± 6.3). The women attend antenatal clinic at the State Specialist Hospital, a secondary health facility in Maiduguri, Borno state. The women are all heterosexuals. The distribution of HBsAg carrier rate according to age of women studied showed a significant (p = 0.0061) increase of the prevalence of HBsAg from 4 (8.7%) in the lower age group (39 years). According to the number of pregnancies, the prevalence of HBsAg infection increased significantly from 6 (9.2%) among primiparous to 13 (13.7%) and 14 (38.9%) among multiparous and grand multiparous respectively. The carrier rate of HBsAg infection among the pregnant women studied based on their duration of pregnancies and their social class showed no significant differences. However, according to the factors known to be commonly associated with the highest risk of transmission of HBV such as history of blood transfusion, Tribal marks/tattooing, use of sharps, sharing of articles, history of jaundice in the women and husbands, history of sexually transmitted infections (STIs) of the women and husbands and the type of marriage (monogamous or polygamous), number of sexual relationships per week, only the history of blood transfusion was significantly associated with HBsAg carrier rate (RR = 3.71., 95% Confidence Interval (C.I.), 1.89-7.30, p = 0.0078). The study confirms that pregnant women who attend antenatal clinic in this secondary health facility are at higher risk of being infected with the HBV, which could lead to both prenatal and post natal transmission to their newborns.展开更多
目的分析乙型肝炎（乙肝）疫苗（Hepatitis B Vaccine，HepB）广泛使用后，乙肝病毒表面抗原（HBsAg）在不同时期、不同人群的携带情况，为乙肝的预防控制提供依据。方法以全市≤18岁人群为调查对象，采用酶联免疫吸附试验检测人群中HB...目的分析乙型肝炎（乙肝）疫苗（Hepatitis B Vaccine，HepB）广泛使用后，乙肝病毒表面抗原（HBsAg）在不同时期、不同人群的携带情况，为乙肝的预防控制提供依据。方法以全市≤18岁人群为调查对象，采用酶联免疫吸附试验检测人群中HBsAg携带情况。结果2000年检测12847人，HBsAg阳性1097例，阳性率8．54％；2006年检测102699人，HBsAg阳性2399例，阳性率2．34％。随着2000年对全市1～18岁人群HepB查漏普种和世界银行贷款疾病控制项目计划免疫子项目HepB接种的实施，尤其是2002年HepB纳入免疫规划后，各个年龄段人群HepB接种率大幅度提高，经过6年时间≤18岁人群HBsAg阳性率下降72.59％，0～、4～、8～、12～、15～18岁人群HBsAg阳性率分别由2000年的3．76％、4．74％、5．59％、8．51％、12．58％下降到2006年的0．30％、1．39％、2．52％、3．03％、2．98％，各年龄段人群HBsAg阳性率下降非常显著。结论各年龄段人群中HBsAg阳性率的下降与HepB接种有直接关系，HepB对预防控制乙肝病毒感染效果明显，提示除做好新生儿HepB预防接种外，成人HepB接种应逐步加强。展开更多
文摘A serological survey conducted among 196 pregnant women resident in and around Maiduguri, an urban town in north eastern Nigeria showed that 33 (16.8%) were asymptomatic carriers of hepatitis B virus surface antigen (HBsAg). They are within the age range of 14-40 years with mean (± SD) age of 24.7 (± 6.3). The women attend antenatal clinic at the State Specialist Hospital, a secondary health facility in Maiduguri, Borno state. The women are all heterosexuals. The distribution of HBsAg carrier rate according to age of women studied showed a significant (p = 0.0061) increase of the prevalence of HBsAg from 4 (8.7%) in the lower age group (39 years). According to the number of pregnancies, the prevalence of HBsAg infection increased significantly from 6 (9.2%) among primiparous to 13 (13.7%) and 14 (38.9%) among multiparous and grand multiparous respectively. The carrier rate of HBsAg infection among the pregnant women studied based on their duration of pregnancies and their social class showed no significant differences. However, according to the factors known to be commonly associated with the highest risk of transmission of HBV such as history of blood transfusion, Tribal marks/tattooing, use of sharps, sharing of articles, history of jaundice in the women and husbands, history of sexually transmitted infections (STIs) of the women and husbands and the type of marriage (monogamous or polygamous), number of sexual relationships per week, only the history of blood transfusion was significantly associated with HBsAg carrier rate (RR = 3.71., 95% Confidence Interval (C.I.), 1.89-7.30, p = 0.0078). The study confirms that pregnant women who attend antenatal clinic in this secondary health facility are at higher risk of being infected with the HBV, which could lead to both prenatal and post natal transmission to their newborns.
文摘目的分析乙型肝炎（乙肝）疫苗（Hepatitis B Vaccine，HepB）广泛使用后，乙肝病毒表面抗原（HBsAg）在不同时期、不同人群的携带情况，为乙肝的预防控制提供依据。方法以全市≤18岁人群为调查对象，采用酶联免疫吸附试验检测人群中HBsAg携带情况。结果2000年检测12847人，HBsAg阳性1097例，阳性率8．54％；2006年检测102699人，HBsAg阳性2399例，阳性率2．34％。随着2000年对全市1～18岁人群HepB查漏普种和世界银行贷款疾病控制项目计划免疫子项目HepB接种的实施，尤其是2002年HepB纳入免疫规划后，各个年龄段人群HepB接种率大幅度提高，经过6年时间≤18岁人群HBsAg阳性率下降72.59％，0～、4～、8～、12～、15～18岁人群HBsAg阳性率分别由2000年的3．76％、4．74％、5．59％、8．51％、12．58％下降到2006年的0．30％、1．39％、2．52％、3．03％、2．98％，各年龄段人群HBsAg阳性率下降非常显著。结论各年龄段人群中HBsAg阳性率的下降与HepB接种有直接关系，HepB对预防控制乙肝病毒感染效果明显，提示除做好新生儿HepB预防接种外，成人HepB接种应逐步加强。
